|
US20030176437A1
(en)
|
2001-08-31 |
2003-09-18 |
D.M. Watterson |
Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
|
|
DE102004010207A1
(de)
|
2004-03-02 |
2005-09-15 |
Aventis Pharma S.A. |
Neue 4-Benzimidazol-2-yl-pyridazin-3-on-Derivate
|
|
DE102004010194A1
(de)
*
|
2004-03-02 |
2005-10-13 |
Aventis Pharma Deutschland Gmbh |
4-Benzimidazol-2-yl-pyridazin-3-on-Derivate, ihre Herstellung und Verwendung in Arzneimitteln
|
|
EP1604988A1
(en)
|
2004-05-18 |
2005-12-14 |
Sanofi-Aventis Deutschland GmbH |
Pyridazinone derivatives, methods for producing them and their use as pharmaceuticals
|
|
EP1598348A1
(en)
|
2004-05-18 |
2005-11-23 |
Aventis Pharma Deutschland GmbH |
Novel pyridazinone derivatives as inhibitors of CDK2
|
|
MX2007003327A
(es)
|
2004-09-20 |
2007-06-05 |
Xenon Pharmaceuticals Inc |
Derivados heterociclicos, y su uso como mediadores de estearoil-coa desaturasa.
|
|
MX2007003332A
(es)
|
2004-09-20 |
2007-06-05 |
Xenon Pharmaceuticals Inc |
Derivados heterociclicos y su uso como inhibidores de estearoil-coa-desaturasa.
|
|
JP4958786B2
(ja)
|
2004-09-20 |
2012-06-20 |
ゼノン・ファーマシューティカルズ・インコーポレイテッド |
複素環誘導体および治療薬としてのそれらの使用
|
|
MX2007003319A
(es)
|
2004-09-20 |
2007-06-05 |
Xenon Pharmaceuticals Inc |
Derivados heterociclicos y su uso como agentes terapeuticos.
|
|
EP2269610A3
(en)
|
2004-09-20 |
2011-03-09 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
|
|
EP1799667B1
(en)
|
2004-09-20 |
2013-03-20 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as therapeutic agents
|
|
EP2289510A1
(en)
|
2004-09-20 |
2011-03-02 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
|
|
EP1812408B1
(en)
|
2004-11-02 |
2013-10-09 |
Northwestern University |
Pyridazine compounds, compositions and methods
|
|
WO2006050359A2
(en)
|
2004-11-02 |
2006-05-11 |
Northwestern University |
Pyridazine compounds and methods
|
|
BRPI0611187A2
(pt)
|
2005-06-03 |
2010-08-24 |
Xenon Pharmaceuticals Inc |
derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
|
|
EP2258359A3
(en)
|
2005-08-26 |
2011-04-06 |
Braincells, Inc. |
Neurogenesis by muscarinic receptor modulation with sabcomelin
|
|
JP2009506069A
(ja)
|
2005-08-26 |
2009-02-12 |
ブレインセルス,インコーポレイティド |
ムスカリン性受容体調節による神経発生
|
|
US7985756B2
(en)
|
2005-10-21 |
2011-07-26 |
Braincells Inc. |
Modulation of neurogenesis by PDE inhibition
|
|
WO2007053596A1
(en)
|
2005-10-31 |
2007-05-10 |
Braincells, Inc. |
Gaba receptor mediated modulation of neurogenesis
|
|
US20100216734A1
(en)
|
2006-03-08 |
2010-08-26 |
Braincells, Inc. |
Modulation of neurogenesis by nootropic agents
|
|
WO2007127474A2
(en)
*
|
2006-04-28 |
2007-11-08 |
Northwestern University |
Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
|
|
BRPI0710938A2
(pt)
|
2006-04-28 |
2012-06-26 |
Univ Northwestern |
formulações contendo compostos de piridazina para o tratamento de doenças neuroinflamatórias
|
|
WO2007127475A2
(en)
*
|
2006-04-28 |
2007-11-08 |
Northwestern University |
Pyridazines for demyelinating diseases and neuropathic pain
|
|
WO2007134136A2
(en)
|
2006-05-09 |
2007-11-22 |
Braincells, Inc. |
Neurogenesis by modulating angiotensin
|
|
BRPI0715160A2
(pt)
|
2006-08-08 |
2013-06-11 |
Sanofi Aventis |
imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
|
|
US20100184806A1
(en)
|
2006-09-19 |
2010-07-22 |
Braincells, Inc. |
Modulation of neurogenesis by ppar agents
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
CN101537006B
(zh)
|
2008-03-18 |
2012-06-06 |
中国科学院上海药物研究所 |
哒嗪酮类化合物在制备抗肿瘤药物中的用途
|
|
US9212146B2
(en)
|
2008-03-18 |
2015-12-15 |
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences |
Substituted pyridazinones for the treatment of tumors
|
|
WO2010003624A2
(en)
|
2008-07-09 |
2010-01-14 |
Sanofi-Aventis |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
WO2010099217A1
(en)
|
2009-02-25 |
2010-09-02 |
Braincells, Inc. |
Modulation of neurogenesis using d-cycloserine combinations
|
|
AU2012203023C1
(en)
*
|
2009-03-02 |
2013-11-07 |
Novartis Ag |
N-(hetero)aryl, 2- (hetero)aryl-substituted acetamides for use as Wnt signaling modulators
|
|
UA103918C2
(en)
*
|
2009-03-02 |
2013-12-10 |
Айерем Элелси |
N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
|
|
DK2470552T3
(en)
|
2009-08-26 |
2014-02-17 |
Sanofi Sa |
NOVEL, CRYSTALLINE, heteroaromatic FLUORGLYCOSIDHYDRATER, MEDICINES COVERING THESE COMPOUNDS AND THEIR USE
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8933024B2
(en)
|
2010-06-18 |
2015-01-13 |
Sanofi |
Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
UY33469A
(es)
|
2010-06-29 |
2012-01-31 |
Irm Llc Y Novartis Ag |
Composiciones y metodos para modular la via de señalizacion de wnt
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
EP2766349B1
(de)
|
2011-03-08 |
2016-06-01 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8710050B2
(en)
|
2011-03-08 |
2014-04-29 |
Sanofi |
Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
WO2012120050A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2012120056A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8809325B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
|
|
WO2012120058A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2012120054A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
GB201201100D0
(en)
*
|
2012-01-20 |
2012-03-07 |
Medical Res Council |
Polypeptides and methods
|
|
DK3290407T3
(da)
|
2013-10-18 |
2020-03-23 |
Celgene Quanticel Res Inc |
Bromodomæneinhibitorer
|
|
WO2015127137A1
(en)
*
|
2014-02-19 |
2015-08-27 |
Aldea Pharmaceuticals, Inc. |
Mitochondrial aldehyde dehydrogenase 2 (aldh2) binding polycyclic amides and their use for the treatment of cancer
|
|
EA201892666A1
(ru)
*
|
2016-05-25 |
2019-08-30 |
Байер Фарма Акциенгезельшафт |
3-оксо-2,6-дифенил-2,3-дигидропиридазин-4-карбоксамиды
|
|
CN116531380B
(zh)
*
|
2017-02-09 |
2025-11-07 |
拜耳股份公司 |
用于治疗癌症的2-杂芳基-3-氧代-2,3-二氢哒嗪-4-甲酰胺
|
|
US11459312B2
(en)
|
2017-11-21 |
2022-10-04 |
Bayer Aktiengesellschaft |
Sulphur substituted 3-oxo-2,3-dihydropyridazine-4-carboxamides
|
|
AU2019318209B2
(en)
|
2018-08-10 |
2025-09-25 |
Diapin Therapeutics, Llc |
Tri-peptides and treatment of metabolic, cardiovascular and inflammatory disorders
|
|
CN111533697B
(zh)
*
|
2020-05-07 |
2023-03-31 |
成都大学 |
4-氨基哒嗪酮类化合物及其制备方法
|
|
CN111533735A
(zh)
*
|
2020-05-08 |
2020-08-14 |
张建蒙 |
氧代二氢哒嗪噻唑类衍生物及其在抗肿瘤药物中的应用
|
|
CN111393374A
(zh)
*
|
2020-05-08 |
2020-07-10 |
张建蒙 |
氧代二氢哒嗪类衍生物及其在抗肿瘤药物中的应用
|
|
WO2022113003A1
(en)
|
2020-11-27 |
2022-06-02 |
Rhizen Pharmaceuticals Ag |
Cdk inhibitors
|
|
WO2022149057A1
(en)
|
2021-01-05 |
2022-07-14 |
Rhizen Pharmaceuticals Ag |
Cdk inhibitors
|
|
AU2022271290A1
(en)
|
2021-05-07 |
2023-11-23 |
Kymera Therapeutics, Inc. |
Cdk2 degraders and uses thereof
|