JP2006506955A5 - - Google Patents
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- Publication number
- JP2006506955A5 JP2006506955A5 JP2004501459A JP2004501459A JP2006506955A5 JP 2006506955 A5 JP2006506955 A5 JP 2006506955A5 JP 2004501459 A JP2004501459 A JP 2004501459A JP 2004501459 A JP2004501459 A JP 2004501459A JP 2006506955 A5 JP2006506955 A5 JP 2006506955A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- cdr
- antibody molecule
- sequence shown
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0210121.0A GB0210121D0 (en) | 2002-05-02 | 2002-05-02 | Biological products |
| PCT/GB2003/001934 WO2003093320A2 (en) | 2002-05-02 | 2003-05-02 | Antibodies specific for human cd22 and their therapeuatic and digagnostic uses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009205660A Division JP5377173B2 (ja) | 2002-05-02 | 2009-09-07 | 生物学的製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006506955A JP2006506955A (ja) | 2006-03-02 |
| JP2006506955A5 true JP2006506955A5 (https=) | 2008-10-23 |
| JP4486494B2 JP4486494B2 (ja) | 2010-06-23 |
Family
ID=9935990
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004501459A Expired - Lifetime JP4486494B2 (ja) | 2002-05-02 | 2003-05-02 | 生物学的製剤 |
| JP2009205660A Expired - Lifetime JP5377173B2 (ja) | 2002-05-02 | 2009-09-07 | 生物学的製剤 |
| JP2013140245A Expired - Lifetime JP5920934B2 (ja) | 2002-05-02 | 2013-07-04 | 生物学的製剤 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009205660A Expired - Lifetime JP5377173B2 (ja) | 2002-05-02 | 2009-09-07 | 生物学的製剤 |
| JP2013140245A Expired - Lifetime JP5920934B2 (ja) | 2002-05-02 | 2013-07-04 | 生物学的製剤 |
Country Status (34)
| Country | Link |
|---|---|
| US (8) | US7355011B2 (https=) |
| EP (1) | EP1504035B9 (https=) |
| JP (3) | JP4486494B2 (https=) |
| KR (3) | KR101386376B1 (https=) |
| CN (3) | CN101134779B (https=) |
| AT (1) | ATE462729T3 (https=) |
| AU (1) | AU2003223007C1 (https=) |
| BE (1) | BE2017C068I2 (https=) |
| CA (1) | CA2484420C (https=) |
| CO (1) | CO5631451A2 (https=) |
| CY (3) | CY1110134T1 (https=) |
| DE (1) | DE60331910D1 (https=) |
| DK (1) | DK1504035T6 (https=) |
| EC (1) | ECSP045470A (https=) |
| ES (1) | ES2341708T7 (https=) |
| FR (1) | FR17C1062I2 (https=) |
| GB (1) | GB0210121D0 (https=) |
| HU (2) | HUS1700055I1 (https=) |
| IL (1) | IL164923A (https=) |
| LT (2) | LTC1504035I2 (https=) |
| LU (2) | LUC00057I2 (https=) |
| MX (1) | MXPA04010787A (https=) |
| NL (1) | NL300920I2 (https=) |
| NO (3) | NO336201B3 (https=) |
| NZ (1) | NZ536757A (https=) |
| PL (1) | PL218433B1 (https=) |
| PT (1) | PT1504035E (https=) |
| RU (1) | RU2342401C2 (https=) |
| SG (1) | SG161744A1 (https=) |
| SI (1) | SI1504035T1 (https=) |
| TW (1) | TWI324161B (https=) |
| UA (1) | UA92580C2 (https=) |
| WO (1) | WO2003093320A2 (https=) |
| ZA (1) | ZA200408851B (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2461351C (en) * | 2001-09-26 | 2014-08-05 | Ira H. Pastan | Mutated anti-cd22 antibodies with increased affinity to cd22-expressing leukemia cells |
| US20110045005A1 (en) | 2001-10-19 | 2011-02-24 | Craig Crowley | Compositions and methods for the treatment of tumor of hematopoietic origin |
| US20040001828A1 (en) | 2002-02-21 | 2004-01-01 | Joseph Tuscano | Treatment methods using anti-CD22 antibodies |
| SI2371392T1 (sl) * | 2002-05-02 | 2015-10-30 | Wyeth Holdings Llc | Konjugati derivat-nosilec kaliheamicina |
| GB0210121D0 (en) * | 2002-05-02 | 2002-06-12 | Celltech R&D Ltd | Biological products |
| GB0312481D0 (en) | 2003-05-30 | 2003-07-09 | Celltech R&D Ltd | Antibodies |
| GT200500283A (es) * | 2004-10-08 | 2006-05-08 | Inmunoterapia de desordenes autoinmunes | |
| MX2007015476A (es) | 2005-06-14 | 2008-02-25 | Amgen Inc | Formulaciones de proteina autoamortiguadoras. |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| EP2650306A1 (en) * | 2006-03-06 | 2013-10-16 | Aeres Biomedical Limited | Humanized Anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
| CA2644906C (en) * | 2006-03-06 | 2016-05-10 | Medimmune, Inc. | Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
| ES2567402T3 (es) | 2006-05-30 | 2016-04-22 | Genentech, Inc. | Anticuerpos anti CD22, sus inmunoconjugados y usos de los mismos |
| KR101552735B1 (ko) | 2006-12-01 | 2015-09-14 | 메다렉스, 엘.엘.시. | 씨디22에 결합하는 인간 항체 및 이의 용도 |
| US8591889B2 (en) | 2008-04-04 | 2013-11-26 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human monoclonal antibodies specific for CD22 |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| US9238878B2 (en) | 2009-02-17 | 2016-01-19 | Redwood Bioscience, Inc. | Aldehyde-tagged protein-based drug carriers and methods of use |
| US8728730B2 (en) | 2009-09-03 | 2014-05-20 | Genentech, Inc. | Methods for treating, diagnosing, and monitoring rheumatoid arthritis |
| AU2012205301B2 (en) | 2011-01-14 | 2017-01-05 | Redwood Bioscience, Inc. | Aldehyde-tagged immunoglobulin polypeptides and method of use thereof |
| BR112013021725A2 (pt) | 2011-02-28 | 2016-11-01 | Genentech Inc | marcadores biológicos e métodos para prever resposta aos antagonistas de células b |
| EP2841459A4 (en) * | 2012-04-26 | 2016-04-13 | Bioatla Llc | ANTI-CD22 ANTIBODIES |
| HK1209768A1 (en) | 2012-07-03 | 2016-04-08 | Washington University | Antibodies to tau |
| KR102165464B1 (ko) | 2012-07-19 | 2020-10-14 | 레드우드 바이오사이언스 인코포레이티드 | Cd22에 대해 특이적인 항체 및 이들의 사용 방법 |
| CN104822705B (zh) | 2012-10-24 | 2019-07-12 | 美国卫生和人力服务部 | M971嵌合抗原受体 |
| CN103214578B (zh) * | 2013-05-10 | 2014-05-28 | 北京东方百泰生物科技有限公司 | 一种新型的人源化抗cd22抗体 |
| CN105828841A (zh) | 2013-11-04 | 2016-08-03 | 辉瑞大药厂 | 抗-efna4抗体-药物缀合物 |
| GB201409558D0 (en) | 2014-05-29 | 2014-07-16 | Ucb Biopharma Sprl | Method |
| TWI664190B (zh) | 2014-06-27 | 2019-07-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| GB201412659D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| MX2017012939A (es) * | 2015-04-08 | 2018-05-22 | Novartis Ag | Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19. |
| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201601077D0 (en) * | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| GB201601075D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies molecules |
| KR102783230B1 (ko) | 2015-11-09 | 2025-03-19 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 항-cd22 항체-메이탄신 콘쥬게이트 및 그것의 사용 방법 |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| GB201521382D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521391D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521383D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl And Ucb Celltech | Method |
| GB201521393D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| AU2017257504A1 (en) | 2016-04-26 | 2018-10-25 | R.P. Scherer Technologies, Llc | Antibody conjugates and methods of making and using the same |
| GB201610512D0 (en) | 2016-06-16 | 2016-08-03 | Autolus Ltd | Chimeric antigen receptor |
| AU2017345490B2 (en) | 2016-10-21 | 2022-07-07 | Amgen Inc. | Pharmaceutical formulations and methods of making the same |
| CN112888709B (zh) | 2018-03-30 | 2024-10-29 | 优瑞科生物技术公司 | 标靶cd22的构建体和其用途 |
| US12448453B2 (en) * | 2020-04-02 | 2025-10-21 | Nanjing IASO Biotechnology Co., Ltd. | Fully human anti-human CD22 chimeric antigen receptor and application thereof |
| US20230331840A1 (en) * | 2020-08-27 | 2023-10-19 | Fapon Biotherapy Inc. | Cd22 antibody and application thereof |
| WO2022262783A1 (zh) * | 2021-06-16 | 2022-12-22 | 西安宇繁生物科技有限责任公司 | 抗cd22的全人源抗体或其抗原结合片段及其制备方法和应用 |
| JP2024534148A (ja) * | 2021-08-27 | 2024-09-18 | ペプトロン インコーポレイテッド | 新規抗muc1抗体およびその用途 |
| CN116217727B (zh) * | 2021-12-06 | 2025-04-29 | 重庆精准生物技术有限公司 | 靶向cd22的抗原结合片段和单链抗体及其应用 |
| US20240166705A1 (en) | 2022-11-07 | 2024-05-23 | Xencor, Inc. | Il18-fc fusion proteins |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957362A (en) * | 1972-10-02 | 1976-05-18 | Corneal Sciences, Inc. | Hydrogels and articles made therefrom |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5134075A (en) * | 1989-02-17 | 1992-07-28 | Oncogen Limited Partnership | Monoclonal antibody to novel antigen associated with human tumors |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| ES2264239T3 (es) * | 1990-06-27 | 2006-12-16 | Princeton University | Complejo de proteinas p53/p90'. |
| EP0531472B1 (en) * | 1991-03-06 | 2003-08-13 | MERCK PATENT GmbH | Humanized monoclonal antibodies |
| US5714350A (en) * | 1992-03-09 | 1998-02-03 | Protein Design Labs, Inc. | Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region |
| US5686072A (en) | 1992-06-17 | 1997-11-11 | Board Of Regents, The University Of Texas | Epitope-specific monoclonal antibodies and immunotoxins and uses thereof |
| US5714340A (en) * | 1992-12-22 | 1998-02-03 | Johnson & Johnson Clinical Diagnostics, Inc. | Immunoassay elements having a receptor zone |
| US6180377B1 (en) * | 1993-06-16 | 2001-01-30 | Celltech Therapeutics Limited | Humanized antibodies |
| US5436265A (en) * | 1993-11-12 | 1995-07-25 | Merck Frosst Canada, Inc. | 1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents |
| US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| EP0804237B8 (en) | 1994-01-25 | 2006-11-08 | Elan Pharmaceuticals, Inc. | Humanized antibodies against leukocyte adhesion molecule vla-4 |
| EP0705903B2 (en) | 1994-08-12 | 2009-08-12 | The University of Utah Research Foundation | Mutations in the 17q-linked breast and ovarian cancer susceptibility gene |
| ES2251723T3 (es) * | 1994-08-12 | 2006-05-01 | Immunomedics, Inc. | Inmunoconjugados y anticuerpos humanizados especificos para linfoma de celulas b y celulas de leucemia. |
| US5714586A (en) * | 1995-06-07 | 1998-02-03 | American Cyanamid Company | Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates |
| US5712374A (en) * | 1995-06-07 | 1998-01-27 | American Cyanamid Company | Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates |
| US7147851B1 (en) * | 1996-08-15 | 2006-12-12 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with α4β7 integrin |
| CA2270288A1 (en) * | 1996-11-01 | 1998-05-14 | Smithkline Beecham Corporation | Human monoclonal antibodies |
| US20020141990A1 (en) * | 1996-11-01 | 2002-10-03 | Smithkline Beecham Corporation | Anti-RSV human monoclonal antibodies |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| EP0970227B1 (en) | 1997-03-20 | 2008-01-09 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Recombinant antibodies and immunoconjugates targeted to cd-22 bearing cells and tumors |
| US6183744B1 (en) | 1997-03-24 | 2001-02-06 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| EP0999853B1 (en) | 1997-06-13 | 2003-01-02 | Genentech, Inc. | Stabilized antibody formulation |
| AT408613B (de) * | 1998-06-17 | 2002-01-25 | Immuno Ag | Pharmazeutisches faktor vii-präparat |
| KR100345463B1 (ko) * | 1998-11-19 | 2003-01-08 | 주)녹십자 | B형간염바이러스의표면항원프리-s1에대한인간화항체및이의제조방법 |
| CA2375912C (en) * | 1999-06-09 | 2014-03-11 | Immunomedics, Inc. | Immunotherapy of autoimmune disorders using antibodies which target b-cells |
| PT1232392E (pt) * | 1999-10-12 | 2003-08-29 | Connex Ges Optimierung Von For | Processo melhorado para deteccao nas fezes de bacterias do genero helicobacter resistentes ao acido |
| US20010046496A1 (en) * | 2000-04-14 | 2001-11-29 | Brettman Lee R. | Method of administering an antibody |
| GB0013810D0 (en) * | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| SG136804A1 (en) * | 2000-07-12 | 2007-11-29 | Idec Pharma Corp | Treatment of b cell malignancies using combination of b cell depleting antibody and immune modulating antibody related applications |
| CN1205479C (zh) * | 2000-10-31 | 2005-06-08 | 杨梦甦 | 免疫学诊断蛋白芯片制备方法 |
| GB0210121D0 (en) * | 2002-05-02 | 2002-06-12 | Celltech R&D Ltd | Biological products |
| SI2371392T1 (sl) | 2002-05-02 | 2015-10-30 | Wyeth Holdings Llc | Konjugati derivat-nosilec kaliheamicina |
| EP2650306A1 (en) * | 2006-03-06 | 2013-10-16 | Aeres Biomedical Limited | Humanized Anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
-
2002
- 2002-05-02 GB GBGB0210121.0A patent/GB0210121D0/en not_active Ceased
-
2003
- 2003-05-02 DK DK03718974.3T patent/DK1504035T6/en active
- 2003-05-02 RU RU2004135103/13A patent/RU2342401C2/ru active
- 2003-05-02 PL PL373277A patent/PL218433B1/pl unknown
- 2003-05-02 SG SG200608406-5A patent/SG161744A1/en unknown
- 2003-05-02 KR KR1020127025129A patent/KR101386376B1/ko not_active Expired - Lifetime
- 2003-05-02 CN CN2007100852904A patent/CN101134779B/zh not_active Expired - Lifetime
- 2003-05-02 EP EP03718974.3A patent/EP1504035B9/en not_active Expired - Lifetime
- 2003-05-02 DE DE60331910T patent/DE60331910D1/de not_active Expired - Lifetime
- 2003-05-02 CN CN201310021287.1A patent/CN103172742B/zh not_active Expired - Lifetime
- 2003-05-02 JP JP2004501459A patent/JP4486494B2/ja not_active Expired - Lifetime
- 2003-05-02 PT PT03718974T patent/PT1504035E/pt unknown
- 2003-05-02 AU AU2003223007A patent/AU2003223007C1/en active Active
- 2003-05-02 SI SI200331804T patent/SI1504035T1/sl unknown
- 2003-05-02 AT AT03718974T patent/ATE462729T3/de unknown
- 2003-05-02 CN CNB038150433A patent/CN100384878C/zh not_active Expired - Lifetime
- 2003-05-02 CA CA2484420A patent/CA2484420C/en not_active Expired - Lifetime
- 2003-05-02 KR KR1020107027192A patent/KR101238970B1/ko not_active Expired - Lifetime
- 2003-05-02 TW TW092112182A patent/TWI324161B/zh not_active IP Right Cessation
- 2003-05-02 KR KR1020047017615A patent/KR101156796B1/ko not_active Expired - Lifetime
- 2003-05-02 UA UA20041209866A patent/UA92580C2/ru unknown
- 2003-05-02 ES ES03718974.3T patent/ES2341708T7/es active Active
- 2003-05-02 US US10/428,408 patent/US7355011B2/en not_active Expired - Lifetime
- 2003-05-02 MX MXPA04010787A patent/MXPA04010787A/es active IP Right Grant
- 2003-05-02 WO PCT/GB2003/001934 patent/WO2003093320A2/en not_active Ceased
- 2003-05-02 NZ NZ536757A patent/NZ536757A/en not_active IP Right Cessation
-
2004
- 2004-10-28 IL IL164923A patent/IL164923A/en active IP Right Grant
- 2004-11-02 ZA ZA2004/08851A patent/ZA200408851B/en unknown
- 2004-11-02 NO NO20044742A patent/NO336201B3/no not_active IP Right Cessation
- 2004-11-30 CO CO04120665A patent/CO5631451A2/es active IP Right Grant
- 2004-12-02 EC EC2004005470A patent/ECSP045470A/es unknown
-
2006
- 2006-09-11 US US11/519,585 patent/US20070059307A1/en not_active Abandoned
-
2008
- 2008-09-23 US US12/235,724 patent/US7919606B2/en not_active Expired - Lifetime
-
2009
- 2009-09-07 JP JP2009205660A patent/JP5377173B2/ja not_active Expired - Lifetime
-
2010
- 2010-06-03 CY CY20101100492T patent/CY1110134T1/el unknown
-
2011
- 2011-03-16 US US13/049,087 patent/US8895714B2/en not_active Expired - Lifetime
-
2012
- 2012-07-13 US US13/548,542 patent/US20120302739A1/en not_active Abandoned
-
2013
- 2013-07-04 JP JP2013140245A patent/JP5920934B2/ja not_active Expired - Lifetime
-
2016
- 2016-03-14 US US15/069,078 patent/US20160326247A1/en not_active Abandoned
-
2017
- 2017-01-27 US US15/417,973 patent/US20170145114A1/en not_active Abandoned
- 2017-12-20 CY CY2017046C patent/CY2017046I2/el unknown
- 2017-12-21 LT LTPA2017044C patent/LTC1504035I2/lt unknown
- 2017-12-21 NL NL300920C patent/NL300920I2/nl unknown
- 2017-12-21 NO NO2017068C patent/NO2017068I1/no unknown
- 2017-12-21 LU LU00057C patent/LUC00057I2/en unknown
- 2017-12-21 CY CY2017045C patent/CY2017045I1/el unknown
- 2017-12-21 FR FR17C1062C patent/FR17C1062I2/fr active Active
- 2017-12-21 LT LTPA2017043C patent/LTPA2017043I1/lt unknown
- 2017-12-21 BE BE2017C068C patent/BE2017C068I2/nl unknown
- 2017-12-21 LU LU00058C patent/LUC00058I2/en unknown
- 2017-12-21 NO NO2017069C patent/NO2017069I1/no unknown
- 2017-12-22 HU HUS1700055C patent/HUS1700055I1/hu unknown
- 2017-12-22 HU HUS1700056C patent/HUS1700056I1/hu unknown
-
2021
- 2021-01-19 US US17/151,911 patent/US20210371547A1/en not_active Abandoned
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