JP2005527605A5 - - Google Patents

Download PDF

Info

Publication number
JP2005527605A5
JP2005527605A5 JP2004504990A JP2004504990A JP2005527605A5 JP 2005527605 A5 JP2005527605 A5 JP 2005527605A5 JP 2004504990 A JP2004504990 A JP 2004504990A JP 2004504990 A JP2004504990 A JP 2004504990A JP 2005527605 A5 JP2005527605 A5 JP 2005527605A5
Authority
JP
Japan
Prior art keywords
composition
methyl
alkyl
compound
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004504990A
Other languages
English (en)
Japanese (ja)
Other versions
JP4615309B2 (ja
JP2005527605A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/015948 external-priority patent/WO2003096991A2/en
Publication of JP2005527605A publication Critical patent/JP2005527605A/ja
Publication of JP2005527605A5 publication Critical patent/JP2005527605A5/ja
Application granted granted Critical
Publication of JP4615309B2 publication Critical patent/JP4615309B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2004504990A 2002-05-17 2003-05-19 白内障および他の眼球疾患の進行の改善 Expired - Fee Related JP4615309B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38128702P 2002-05-17 2002-05-17
PCT/US2003/015948 WO2003096991A2 (en) 2002-05-17 2003-05-19 Amelioration of the development of cataracts and other opthalmic diseases

Publications (3)

Publication Number Publication Date
JP2005527605A JP2005527605A (ja) 2005-09-15
JP2005527605A5 true JP2005527605A5 (https=) 2006-06-29
JP4615309B2 JP4615309B2 (ja) 2011-01-19

Family

ID=29550095

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004504990A Expired - Fee Related JP4615309B2 (ja) 2002-05-17 2003-05-19 白内障および他の眼球疾患の進行の改善

Country Status (13)

Country Link
US (3) US7442711B2 (https=)
EP (1) EP1507826A4 (https=)
JP (1) JP4615309B2 (https=)
KR (1) KR20060013632A (https=)
CN (1) CN100469776C (https=)
AU (1) AU2003243282B2 (https=)
BR (1) BR0310057A (https=)
CA (1) CA2484512C (https=)
IL (1) IL164639A (https=)
MX (1) MXPA04011416A (https=)
NO (1) NO20045483L (https=)
WO (1) WO2003096991A2 (https=)
ZA (1) ZA200408449B (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060013632A (ko) * 2002-05-17 2006-02-13 오쎄라 파마슈티걸즈, 인크. 백내장 및 다른 안질환 발병의 개선
US20040057983A1 (en) 2002-09-25 2004-03-25 David Schmidt Biomolecular wearable apparatus
AU2003300471A1 (en) * 2003-01-03 2004-08-10 Eric F. Bernstein Methods for treating ocular diseases
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
US7589107B2 (en) * 2003-05-19 2009-09-15 Othera Holding, Inc. Amelioration of vitrectomy-induced cataracts
EP1689354A4 (en) * 2003-11-20 2010-07-14 Othera Holding Inc REDUCTION OF CATARACTS, MACULAR GENERATION AND OTHER EYES DISEASES
CA2546042A1 (en) * 2003-11-20 2005-06-09 Othera Pharmaceuticals, Inc. Amelioration of macular degeneration and other ophthalmic diseases
US20080312283A1 (en) * 2005-05-26 2008-12-18 Othera Pharmaceuticals, Inc. Use of Hydroxylamine Derivates for Inhibiting Vitrectomy-Induced Cataracts
US20070197599A1 (en) * 2006-02-02 2007-08-23 Matier William L Hydroxylamines and derivatives as anti-angiogenic agents
US20070203190A1 (en) * 2006-02-22 2007-08-30 Ghanshyam Patil Hydroxylamines and derivatives for the inhibition of complement activation
US20070197593A1 (en) * 2006-02-22 2007-08-23 Matier William L Hydroxylamines and derivatives for treatment of inflammatory conditions of the liver
CA2678363A1 (en) * 2007-02-16 2008-08-21 Othera Holding, Inc. Drug resistance reversal in neoplastic disease
BRPI0807571A2 (pt) 2007-02-22 2014-07-01 Othera Holding Inc Compostos de hidroxilamina e métodos de seu uso
EP2217589A4 (en) * 2007-11-28 2012-02-22 Revision Therapeutics Inc MODULATORS OF OCULAR OXIDATIVE STRESS
US8602961B2 (en) 2008-05-15 2013-12-10 Lifewave Products Llc Apparatus and method of stimulating elevation of glutathione levels in a subject
WO2011059474A1 (en) 2009-10-30 2011-05-19 Nestec S.A. Methods for maintaining eye health and ameliorating opthalmic maladies in canines
US8778969B2 (en) 2009-11-07 2014-07-15 Peter H Proctor Nitrone, nitroso, and nitroxide spintraps and spin labels and their hydroxylamines
EP2397474A1 (de) * 2010-06-17 2011-12-21 Construction Research & Technology GmbH 2-Oxo-1,3-dioxolan-4-carbonsäureester, ihre Herstellung und Verwendung
US9012647B2 (en) 2011-04-07 2015-04-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nitroxide modified non-steroidal anti-inflammatory compounds and uses thereof in the treatment and prevention of diseases or disorders
EP2514800B2 (de) 2011-04-21 2018-03-07 Merck Patent GmbH Verbindungen und flüssigkristallines Medium
JP6072067B2 (ja) * 2011-12-22 2017-02-01 コンストラクション リサーチ アンド テクノロジー ゲーエムベーハーＣｏｎｓｔｒｕｃｔｉｏｎ Ｒｅｓｅａｒｃｈ ＆ Ｔｅｃｈｎｏｌｏｇｙ ＧｍｂＨ ２−オキソ−１，３−ジオキソラン−４−カルボキサミド、その製造方法および使用
CN102584683B (zh) * 2012-02-29 2014-12-24 中国人民解放军第四军医大学 Tempol类衍生物的合成及辐射防护作用
EP2818465A1 (en) * 2013-06-26 2014-12-31 Construction Research & Technology GmbH 2-Oxo-1,3-dioxolane-4-acyl halides, their preparation and use
US9314457B2 (en) 2014-06-19 2016-04-19 The University Of Utah Research Foundation Methods of treating and preventing vascular instability diseases
CN116963727A (zh) * 2020-11-13 2023-10-27 普莱克斯医药公司 用于治疗眼部病症的药剂
PL441664A1 (pl) * 2022-07-07 2024-01-08 Uniwersytet Warszawski Nitroksylowa pochodna polifenolu, sposoby jej wytwarzania oraz jej zastosowanie

Family Cites Families (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3936456A (en) 1972-03-24 1976-02-03 Ciby-Geigy Corporation Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby
US4014335A (en) 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
NL188266C (nl) 1975-07-29 1992-05-18 Merck & Co Inc Werkwijze ter bereiding van een oogheelkundig inplantaat.
US4287175A (en) 1978-06-22 1981-09-01 Merck & Co., Inc. Contact lens wetting agents
JPS5899449A (ja) 1981-12-09 1983-06-13 Sanyo Chem Ind Ltd カチオン性ビニルモノマ−の安定化法
US4404302A (en) 1982-05-27 1983-09-13 Ferro Corporation Acylated hindered hexahydropyrimidines and their use as light stabilizing agents
US4590231A (en) 1983-10-11 1986-05-20 Ciba-Geigy Corporation Polyolefin compositions stabilized against degradation using hydroxylamine derivatives
EP0163696B1 (en) 1983-11-14 1992-11-25 Columbia Laboratories, Inc. Use of a bioadhesive
US5225196A (en) 1983-11-14 1993-07-06 Columbia Laboratories, Inc. Bioadhesive compositions and methods of treatment therewith
US4983392A (en) 1983-11-14 1991-01-08 Bio-Mimetics, Inc. Bioadhesive compositions and methods of treatment therewith
EP0157738B1 (de) 1984-03-22 1989-04-19 Ciba-Geigy Ag Verfahren zur Herstellung von Nitroxylen sterisch gehinderter Amine
US4691015A (en) 1984-07-23 1987-09-01 Ciba-Geigy Corporation Hydroxylamines derived from hindered amines
US5209927A (en) 1985-01-23 1993-05-11 Alcon Laboratories, Inc. Ophthalmic solution
US4668699A (en) 1985-08-05 1987-05-26 Merck & Co., Inc. Novel HMG-CoA reductase inhibitors
US4883658A (en) 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4804539A (en) 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
JPS6385547A (ja) 1986-09-29 1988-04-16 Fuji Photo Film Co Ltd ハロゲン化銀カラ−写真感光材料
US4818537A (en) 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
FR2608045B1 (fr) 1986-12-12 1990-03-02 Chauvin Laboratoires Utilisation d'inhibiteurs de xanthine- oxydase, de piegeurs de radicaux libres oxygenes et de chelateurs du fer pour la fabrication d'une composition pharmaceutique destinee au traitement du glaucome et compositions pharmaceutiques destinees au traitement du glaucome
US5278151A (en) 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US4914088A (en) 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
EP0309401B2 (en) 1987-09-21 2002-06-05 Ciba Specialty Chemicals Holding Inc. Stabilization of coatings with N-hydroxy hindered amines
EP0309400B1 (en) 1987-09-21 1994-03-02 Ciba-Geigy Ag N-acyloxy hindered amine stabilizers
DE3801790A1 (de) 1988-01-22 1989-07-27 Resart Ihm Ag Kunststoffmaterial mit hoher uv-durchlaessigkeit, verfahren zu dessen herstellung und dessen verwendung
DE58907159D1 (de) 1988-06-14 1994-04-14 Ciba Geigy Verfahren zum fotochemischen Stabilisieren von ungefärbten und gefärbten Polypropylenfasern.
US5073278A (en) 1988-07-18 1991-12-17 Ciba-Geigy Corporation Lubricant composition
US5004770A (en) 1988-10-19 1991-04-02 Ciba-Geigy Corporation Polymeric substrates stabilized with N-substituted hindered amines
US4927891A (en) 1988-11-23 1990-05-22 Pennwalt Corporation Polymer bound light stabilizer coating resins
US5030243A (en) 1989-01-05 1991-07-09 Ciba-Geigy Corporation Process for the photochemical stabilization of undyed and dyeable artificial leather with a sterically hindered amine
DE4000551A1 (de) 1989-01-13 1990-07-19 Ciba Geigy Ag Verfahren zum fotochemischen stabilisieren von gefaerbter wolle
US5145893A (en) * 1989-03-21 1992-09-08 Ciba-Geigy Corporation Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers
US5075104A (en) 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
JPH0331342A (ja) 1989-06-28 1991-02-12 Mitsubishi Petrochem Co Ltd ポリオレフィン樹脂組成物
EP0432089B1 (de) 1989-11-08 1996-09-04 Ciba-Geigy Ag Schmierstoffzusammensetzungen
DK0787492T3 (da) 1990-03-16 2004-02-02 Us Secretary United States Dep Anvendelse af nitroxider og oxazolidiner til beskyttelse mod ioniserende stråling og oxidativt stress
ZA912797B (en) 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
EP0459148B1 (en) 1990-05-29 1996-01-03 Ocular Research Of Boston Inc. Dry eye treatment composition
EP0467850B1 (en) 1990-07-20 1995-09-06 Ciba-Geigy Ag Stabilized monomer compositions
KR100193146B1 (ko) * 1990-07-20 1999-06-15 월터 클리웨인, 한스-피터 위트린 안정화된 단량체 조성물
US5290888A (en) 1990-07-20 1994-03-01 Ciba-Geigy Corporation Process for stabilizing ethylenically unsaturated compounds and stabilized monomer compositions
JPH04166930A (ja) 1990-10-31 1992-06-12 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
US5475013A (en) 1990-11-19 1995-12-12 Monsanto Company Retroviral protease inhibitors
FR2670517B1 (fr) 1990-12-13 1993-04-09 Normandie Const Meca Element de franchissement pour le franchissement d'obstacles.
CA2058823A1 (en) 1991-01-08 1992-07-09 Rolf Schumacher Lubricant compositions
JP2681424B2 (ja) 1991-04-12 1997-11-26 富士写真フイルム株式会社 ハロゲン化銀カラー写真感光材料
IT1246779B (it) 1991-04-12 1994-11-26 Ciba Geigy Spa Composti piperidinici atti all'impiego come stabilizzanti per materiali organici.
US5399473A (en) 1991-04-12 1995-03-21 Fuji Photo Film Company, Ltd. Silver halide color photographic material
ES2101994T3 (es) 1992-04-08 1997-07-16 Ciba Geigy Ag Antioxidantes liquidos como estabilizadores.
DE4327297B4 (de) 1992-08-17 2007-05-24 Clariant Finance (Bvi) Ltd. Verwendung von Piperidinverbindungen
TW237471B (https=) 1992-09-03 1995-01-01 Ciba Geigy
JPH06172592A (ja) 1992-12-09 1994-06-21 Sumitomo Chem Co Ltd カーボンブラック含有ポリオレフィン系樹脂組成物
US5707643A (en) 1993-02-26 1998-01-13 Santen Pharmaceutical Co., Ltd. Biodegradable scleral plug
CH688878B5 (de) 1993-04-06 1998-11-13 Ciba Geigy Ag Handelsformen von sterisch gehindertem Amin und deren Verwendung.
IT1270975B (it) 1993-06-03 1997-05-26 Ciba Geigy Spa Composti piperidin-triazinici atti all'impiego come stabilizzanti allaluce, al calore e alla ossidazione per materiali organici
DE4320444A1 (de) 1993-06-21 1994-12-22 Agfa Gevaert Ag Farbfotografisches Aufzeichnungsmaterial
IT1264946B1 (it) 1993-07-16 1996-10-17 Ciba Geigy Spa Derivati del 2,2,6,6-tetrametil-4-piperidinolo utili come stabilizzanti alla luce ed all'ossidazione per materiali organici.
IT1264817B1 (it) 1993-07-28 1996-10-10 Ciba Geigy Spa Derivati di polialchil-4-piperidinoli atti all'impderivati di polialchil-4-piperidinoli atti all'impiego come stabilizzanti per materiali organici iego come stabilizzanti per materiali organici
EP0638616A1 (de) 1993-08-13 1995-02-15 Ciba-Geigy Ag Pigmentsalze
CA2131047A1 (en) 1993-09-01 1995-03-02 Takashi Sanada Thermoplastic resin composition
GB9318846D0 (en) 1993-09-10 1993-10-27 Sandoz Ltd Improvements in or relating to organic compounds
TW327185B (en) 1993-09-20 1998-02-21 Ciba Sc Holding Ag Liquid antioxidants
WO1995017900A1 (en) 1993-12-30 1995-07-06 Arcturus Pharmaceutical Corporation Methods for the treatment of the central nervous system or eye involving pathogenic oxidation pathways
DE59505941D1 (de) 1994-01-19 1999-06-24 Ciba Geigy Ag Stabilisieren von Leder gegen thermische und photochemische Zersetzung
US5466233A (en) 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
DE69425287T2 (de) 1994-11-15 2001-03-15 Moreno Paolini N-hydroxypiperidine als superoxid-radikalfänger
US5725493A (en) 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US5518732A (en) 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
IT1273607B (it) 1995-04-26 1997-07-08 Ciba Geigy Spa Combinazione di stabilizzanti per polimeri sintetici organici
US5699182A (en) 1995-05-25 1997-12-16 Xytronyx, Inc. Light fatigue resistant photochromic formulations
TW416970B (en) 1995-05-31 2001-01-01 Ciba Sc Holding Ag Carrier-bound light stabilizers and antioxidants as fillers and stabilizers
US5718922A (en) 1995-05-31 1998-02-17 Schepens Eye Research Institute, Inc. Intravitreal microsphere drug delivery and method of preparation
US6469057B1 (en) * 1995-06-02 2002-10-22 Mcw Research Foundation, Inc. Methods for in vivo reduction of free radical levels and compositions useful therefor
US5869079A (en) 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
DE19530468A1 (de) 1995-08-18 1997-02-20 Sandoz Ag Verwendung von Piperidinverbindungen
JPH0952975A (ja) 1995-08-18 1997-02-25 Clariant Internatl Ltd 顔料の安定化方法及びこの方法に用いる組成物
EP0761466B1 (en) 1995-08-30 1999-08-04 Eastman Kodak Company Stabilised dye-donor element for use in thermal dye transfer
US5821374A (en) 1995-11-21 1998-10-13 Hoffmann-La Roche Inc. Process for the oxidation of alcohols
US6001853A (en) 1996-01-26 1999-12-14 The United States Of America As Represented By The Department Of Health And Human Services Hydroxylamine compositions for the prevention or retardation of cataracts
GB9607565D0 (en) 1996-04-12 1996-06-12 Clariant Int Ltd Stabilizer composition
DE69705040T2 (de) 1996-04-12 2001-09-20 Clariant Finance (Bvi) Ltd., Road Town Stabilisation von polyolefinen
DE19618197A1 (de) 1996-05-07 1997-11-13 Hoechst Ag Neue sterisch gehinderte Piperidinderivate als Lichtschutzmittel für Polymere
JPH1045777A (ja) 1996-07-29 1998-02-17 Sakai Chem Ind Co Ltd 新規な有機リン化合物及びその用途
JPH1045778A (ja) 1996-07-29 1998-02-17 Sakai Chem Ind Co Ltd 新規なヒンダードアミン塩及びその用途
DE69722441T2 (de) 1996-12-19 2004-08-19 Exxonmobil Chemical Patents Inc., Baytown Verfahren zur schmelverarbeitung von amin enthaltendem polyethylen
KR20000069479A (ko) 1996-12-20 2000-11-25 시바 스폐셜티 케미칼스 홀딩 인코포레이티드 고형 기재 재료상에 고정된 에스테르 교환 반응 촉매
EP0895474A4 (en) * 1997-01-29 2003-03-05 A Glenn Braswell LIQUID EYE DROP COMPOSITION
US5981584A (en) 1997-02-06 1999-11-09 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
JPH10220381A (ja) 1997-02-07 1998-08-18 Matsushita Refrig Co Ltd 密閉型圧縮機
JPH10219140A (ja) 1997-02-07 1998-08-18 Nippon Nsc Ltd 耐候性塗料用樹脂エマルション
DE19816681A1 (de) 1997-04-18 1998-10-22 Ciba Geigy Ag Azidhaltige Stabilisatoren
IT1291599B1 (it) 1997-04-18 1999-01-11 Great Lakes Chemical Italia Composti appartenenti alla classe delle enammine e loro utilizzo come antiossidanti per polimeri organici
IT1302988B1 (it) 1997-05-08 2000-10-18 Great Lakes Chemical Italia Polimeri organici stabilizzati alla luce
RU2223985C2 (ru) 1997-07-23 2004-02-20 Циба Спешиалти Кемикалз Холдинг Инк. Ингибирование пожелтения целлюлозы и бумаги с использованием нитроксидов и других совместно вводимых добавок
DE19735255B4 (de) 1997-08-14 2007-08-23 Clariant Produkte (Deutschland) Gmbh Synergistisches Stabilisatorgemisch auf Basis von Polyalkyl-1-oxa-diazaspirodecan-Verbindungen und dessen Verwendung
US5902598A (en) 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
FR2773165B1 (fr) 1997-12-26 2001-06-08 Rhodia Chimie Sa Stabilisation des moules en elastomere silicone
FR2773320B1 (fr) 1998-01-05 2000-03-03 Optisinvest Dispositif pour le transfert intraoculaire de produits actifs par iontophorese
DE19804910A1 (de) 1998-02-07 1999-08-12 Clariant Gmbh Polyolefin-Formmasse zur Herstellung von kalandrierten Folien/Platten
IT1298452B1 (it) 1998-02-26 2000-01-10 Great Lakes Chemical Italia Composizioni fotocromatiche dotate di resistenza a fatica alla luce ed articoli fotocromatici che le contengono
TWI224995B (en) 1998-03-19 2004-12-11 Ciba Sc Holding Ag Stabilization of wood substrates
US6149925A (en) * 1998-11-05 2000-11-21 Color Access, Inc. Topical compositions for enhancing glutathione production
AU3119100A (en) 1998-12-17 2000-07-03 Alcon Laboratories, Inc. Methods for the prevention and treatment of post-surgical complications
US6410045B1 (en) 1999-02-22 2002-06-25 Clyde Lewis Schultz Drug delivery system for antiglaucomatous medication
EP1156809B1 (en) 1999-03-01 2005-12-07 Vista Scientific LLC Mucin containing ophthalmic preparations
US6429194B1 (en) 1999-03-01 2002-08-06 Vista Scientific Llc Mucin containing ophthalmic preparation
JP3527435B2 (ja) 1999-05-21 2004-05-17 ユニ・チャーム株式会社 使い捨ておむつ
TW514581B (en) 1999-09-02 2002-12-21 Ciba Sc Holding Ag A method of protecting wood against light-induced degradation by treatment with an impregnation which penetrates the surface of the wood
US6331313B1 (en) 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
US20010036943A1 (en) * 2000-04-07 2001-11-01 Coe Jotham W. Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US20030109566A1 (en) 2000-06-29 2003-06-12 Tomiya Mano Remedial agent for optic nerve disease and the like
IT1320080B1 (it) 2000-10-25 2003-11-18 Giuliani Spa Composizione per uso farmaceutico o dietetico.
JP4594727B2 (ja) * 2002-05-02 2010-12-08 チバ ホールディング インコーポレーテッド 安定化ボディケア製品、家庭用品、織物材料及び織物
KR20060013632A (ko) 2002-05-17 2006-02-13 오쎄라 파마슈티걸즈, 인크. 백내장 및 다른 안질환 발병의 개선
US7825134B2 (en) 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
JP4288302B1 (ja) 2008-01-18 2009-07-01 トモデータサービス有限会社 位置検出装置および位置検出プログラム並びに施設図面データ

Similar Documents

Publication Publication Date Title
JP2005527605A5 (https=)
RU2002124873A (ru) Глюкопиранозилоксибензилбензольные производные, лекарственные композиции, содержащие эти производные, и промежуточные соединения для получения указанных производных
RU2006133898A (ru) Производные бензимидазола и его применение
RU2011103741A (ru) Композиции и способы лечения заболевания сетчатки
CA2590261A1 (en) Aminopyrazine analogs for treating glaucoma and other rho kinase-mediated diseases and conditions
JP2022527556A5 (https=)
WO2015117024A1 (en) Novel therapeutics for the treatment of glaucoma
CN103249400B (zh) 用于治疗青光眼和高眼压症的腺苷a1激动剂
JP2010514733A5 (https=)
NO20092764L (no) Isosorbid mononitrat derivater for behandling av okular hypertensjon
JP2007527417A5 (https=)
ATE366107T1 (de) Verwendung von sulfodehydroabietinsäure zur behandlung entzündlicher darmerkrankungen
EP4205742A1 (en) Composition for treating coronavirus-19 infection, comprising phenanthroindolizidine and phenanthroquinolizidine alkaloid derivative, optical isomer thereof, or pharmaceutically acceptable salt thereof as active ingredient
JP2003206241A5 (https=)
RU2007101238A (ru) Пептидные агонисты вазопрессинового рецептора
ES2210018T3 (es) Antagonistas de 5ht-2 para regular la presion intraocular y tratar el glaucoma.
US10537579B2 (en) Rejection reaction suppressant
RU2004102398A (ru) Производные бензо[g]хинолина для лечения глаукомы и близорукости
RU2004129767A (ru) Хинолиновые производные
WO2020041344A4 (en) Methods and compositions for drugs to treat ophthalmic diseases
EP4353226A1 (en) Pharmaceutical composition for preventing or treating degenerative eye diseases
RU2019118904A (ru) Распределение в глазу и фармакокинетика композиций лифитеграста
JP2020511437A5 (https=)
JP5224625B2 (ja) 眼科手術において眼圧を制御するための組成物
JP2013513606A (ja) プロスタグランジンアゴニストのプロドラッグの安定した水性組成物およびその使用方法