JP2020511437A5 - - Google Patents
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- Publication number
- JP2020511437A5 JP2020511437A5 JP2019547971A JP2019547971A JP2020511437A5 JP 2020511437 A5 JP2020511437 A5 JP 2020511437A5 JP 2019547971 A JP2019547971 A JP 2019547971A JP 2019547971 A JP2019547971 A JP 2019547971A JP 2020511437 A5 JP2020511437 A5 JP 2020511437A5
- Authority
- JP
- Japan
- Prior art keywords
- chemical formula
- compound represented
- substituted
- unsubstituted
- eye disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 claims 10
- 208000030533 eye disease Diseases 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 229910052736 halogen Inorganic materials 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 238000011282 treatment Methods 0.000 claims 4
- 229920000609 methyl cellulose Polymers 0.000 claims 3
- 239000001923 methylcellulose Substances 0.000 claims 3
- 235000010981 methylcellulose Nutrition 0.000 claims 3
- 238000011321 prophylaxis Methods 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 208000010412 Glaucoma Diseases 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000005843 halogen group Chemical group 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical group O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 claims 2
- 230000004410 intraocular pressure Effects 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 208000022873 Ocular disease Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020170035224A KR101805400B1 (ko) | 2017-03-21 | 2017-03-21 | 아데노신 유도체를 포함하는 녹내장 예방 및 치료용 약학적 조성물 |
| KR10-2017-0035224 | 2017-03-21 | ||
| PCT/KR2018/003274 WO2018174549A1 (ko) | 2017-03-21 | 2018-03-21 | 아데노신 유도체를 포함하는 녹내장 예방 및 치료용 약학적 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020511437A JP2020511437A (ja) | 2020-04-16 |
| JP2020511437A5 true JP2020511437A5 (https=) | 2020-05-28 |
| JP6821050B2 JP6821050B2 (ja) | 2021-01-27 |
Family
ID=60920336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019547971A Active JP6821050B2 (ja) | 2017-03-21 | 2018-03-21 | アデノシン誘導体を含む緑内障の予防及び治療用薬学的組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11185556B2 (https=) |
| EP (1) | EP3603647B1 (https=) |
| JP (1) | JP6821050B2 (https=) |
| KR (1) | KR101805400B1 (https=) |
| CN (1) | CN110381955A (https=) |
| AU (1) | AU2018238996B2 (https=) |
| CA (2) | CA3057277C (https=) |
| WO (1) | WO2018174549A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101805400B1 (ko) | 2017-03-21 | 2017-12-07 | 퓨쳐메디신 주식회사 | 아데노신 유도체를 포함하는 녹내장 예방 및 치료용 약학적 조성물 |
| KR102007640B1 (ko) | 2017-11-29 | 2019-08-07 | 퓨쳐메디신 주식회사 | 아데노신 유도체를 포함하는 망막 질환 또는 시신경 질환 예방 및 치료용 약학적 조성물 |
| CN116350649A (zh) * | 2021-12-28 | 2023-06-30 | 未来制药有限公司 | 预防和/或治疗胆管炎或由其引起的肝疾病的药物组合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2009003750A (es) | 2006-10-06 | 2009-06-18 | Univ Pennsylvania | Suministro eficiente de antagonistas del receptor de adenosina a3 de especies cruzadas, para reducir la presion intraocular. |
| WO2008108508A1 (en) * | 2007-03-07 | 2008-09-12 | Fm Therapeutics Co., Ltd. | Adenosine derivatives, method for the synthesis thereof, and the pharmaceutical compositions for the prevention and treatment of the inflammatory diseases containing the same as an active ingredient |
| WO2012125400A1 (en) * | 2011-03-14 | 2012-09-20 | Acorn Biomedical, Inc. | Compositions and methods using adenosine a3 receptor antagonists for the treatment of inflammatory eye diseases |
| KR101805400B1 (ko) * | 2017-03-21 | 2017-12-07 | 퓨쳐메디신 주식회사 | 아데노신 유도체를 포함하는 녹내장 예방 및 치료용 약학적 조성물 |
| KR101820909B1 (ko) * | 2017-07-07 | 2018-01-23 | 퓨쳐메디신 주식회사 | 아데노신 유도체를 포함하는 만성신장질환 예방 및 치료용 약학적 조성물 |
-
2017
- 2017-03-21 KR KR1020170035224A patent/KR101805400B1/ko active Active
-
2018
- 2018-03-21 CA CA3057277A patent/CA3057277C/en active Active
- 2018-03-21 CN CN201880015381.7A patent/CN110381955A/zh active Pending
- 2018-03-21 EP EP18771758.2A patent/EP3603647B1/en active Active
- 2018-03-21 JP JP2019547971A patent/JP6821050B2/ja active Active
- 2018-03-21 CA CA3159836A patent/CA3159836C/en active Active
- 2018-03-21 AU AU2018238996A patent/AU2018238996B2/en active Active
- 2018-03-21 US US16/492,938 patent/US11185556B2/en active Active
- 2018-03-21 WO PCT/KR2018/003274 patent/WO2018174549A1/ko not_active Ceased
-
2021
- 2021-08-26 US US17/458,231 patent/US12083140B2/en active Active
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