JP2005526076A5 - - Google Patents

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Publication number
JP2005526076A5
JP2005526076A5 JP2003575909A JP2003575909A JP2005526076A5 JP 2005526076 A5 JP2005526076 A5 JP 2005526076A5 JP 2003575909 A JP2003575909 A JP 2003575909A JP 2003575909 A JP2003575909 A JP 2003575909A JP 2005526076 A5 JP2005526076 A5 JP 2005526076A5
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JP
Japan
Prior art keywords
heteroaryl
aryl
heterocyclyl
alkyl
arylalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003575909A
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English (en)
Japanese (ja)
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JP2005526076A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/007565 external-priority patent/WO2003077855A2/en
Publication of JP2005526076A publication Critical patent/JP2005526076A/ja
Publication of JP2005526076A5 publication Critical patent/JP2005526076A5/ja
Pending legal-status Critical Current

Links

JP2003575909A 2002-03-13 2003-03-13 Mek阻害剤としてのn3アルキル化ベンズイミダゾール誘導体 Pending JP2005526076A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36416402P 2002-03-13 2002-03-13
PCT/US2003/007565 WO2003077855A2 (en) 2002-03-13 2003-03-13 N3 alkylated benzimidazole derivatives as mek inhibitors

Publications (2)

Publication Number Publication Date
JP2005526076A JP2005526076A (ja) 2005-09-02
JP2005526076A5 true JP2005526076A5 (enExample) 2006-03-23

Family

ID=28041882

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003575909A Pending JP2005526076A (ja) 2002-03-13 2003-03-13 Mek阻害剤としてのn3アルキル化ベンズイミダゾール誘導体

Country Status (18)

Country Link
US (2) US20030216460A1 (enExample)
EP (1) EP1482944A4 (enExample)
JP (1) JP2005526076A (enExample)
KR (1) KR20040098013A (enExample)
CN (1) CN1652792A (enExample)
AR (1) AR038972A1 (enExample)
AU (1) AU2003220202A1 (enExample)
CA (1) CA2478534A1 (enExample)
CO (1) CO5611145A2 (enExample)
DO (1) DOP2003000614A (enExample)
IL (1) IL163996A0 (enExample)
MX (1) MXPA04008894A (enExample)
PA (1) PA8569201A1 (enExample)
PL (1) PL378635A1 (enExample)
RU (1) RU2300528C2 (enExample)
TW (1) TW200406203A (enExample)
UA (1) UA76837C2 (enExample)
WO (1) WO2003077855A2 (enExample)

Families Citing this family (74)

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JP5311673B2 (ja) 2006-12-14 2013-10-09 エグゼリクシス, インコーポレイテッド Mek阻害剤の使用方法
JO2985B1 (ar) 2006-12-20 2016-09-05 Takeda Pharmaceuticals Co مثبطات كينازmapk/erk
WO2008157179A2 (en) 2007-06-12 2008-12-24 Genentech, Inc. N-substituted azaindoles and methods of use
CN101801955B (zh) 2007-07-05 2013-05-08 阵列生物制药公司 作为akt蛋白激酶抑制剂的嘧啶基环戊烷
US9409886B2 (en) 2007-07-05 2016-08-09 Array Biopharma Inc. Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
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US8022057B2 (en) 2007-11-12 2011-09-20 Takeda Pharmaceutical Company Limited MAPK/ERK kinase inhibitors
NZ586802A (en) * 2007-12-19 2012-03-30 Genentech Inc Imidazo[1,5-a]pyridine and imidazo[1,5-a]pyrazine derivatives for the treatment of inflammatory diseases
CA2704125A1 (en) 2007-12-19 2009-07-09 Genentech, Inc. 8-anilinoimidazopyridines and their use as anti-cancer and/or anti-inflammatory agents
US8486963B2 (en) 2007-12-21 2013-07-16 Genentech, Inc. Azaindolizines and methods of use
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CN102137843A (zh) 2008-07-01 2011-07-27 健泰科生物技术公司 作为mek激酶抑制剂的异吲哚酮衍生物及其使用方法
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CN111646946A (zh) * 2017-11-14 2020-09-11 深圳市塔吉瑞生物医药有限公司 一种取代的苯并咪唑化合物及包含该化合物的组合物
AU2020242287A1 (en) 2019-03-21 2021-09-02 INSERM (Institut National de la Santé et de la Recherche Médicale) A Dbait molecule in combination with kinase inhibitor for the treatment of cancer
KR20220098759A (ko) 2019-11-08 2022-07-12 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 키나제 억제제에 대해 내성을 획득한 암의 치료 방법
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
JP2024521788A (ja) 2021-05-27 2024-06-04 ミラティ セラピューティクス, インコーポレイテッド 併用療法
TW202342018A (zh) 2022-03-04 2023-11-01 美商奇奈特生物製藥公司 Mek激酶抑制劑
WO2025073765A1 (en) 2023-10-03 2025-04-10 Institut National de la Santé et de la Recherche Médicale Methods of prognosis and treatment of patients suffering from melanoma

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