JP2005526076A5 - - Google Patents

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Publication number
JP2005526076A5
JP2005526076A5 JP2003575909A JP2003575909A JP2005526076A5 JP 2005526076 A5 JP2005526076 A5 JP 2005526076A5 JP 2003575909 A JP2003575909 A JP 2003575909A JP 2003575909 A JP2003575909 A JP 2003575909A JP 2005526076 A5 JP2005526076 A5 JP 2005526076A5
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JP
Japan
Prior art keywords
heteroaryl
aryl
heterocyclyl
alkyl
arylalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003575909A
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English (en)
Japanese (ja)
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JP2005526076A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/007565 external-priority patent/WO2003077855A2/en
Publication of JP2005526076A publication Critical patent/JP2005526076A/ja
Publication of JP2005526076A5 publication Critical patent/JP2005526076A5/ja
Pending legal-status Critical Current

Links

JP2003575909A 2002-03-13 2003-03-13 Mek阻害剤としてのn3アルキル化ベンズイミダゾール誘導体 Pending JP2005526076A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36416402P 2002-03-13 2002-03-13
PCT/US2003/007565 WO2003077855A2 (en) 2002-03-13 2003-03-13 N3 alkylated benzimidazole derivatives as mek inhibitors

Publications (2)

Publication Number Publication Date
JP2005526076A JP2005526076A (ja) 2005-09-02
JP2005526076A5 true JP2005526076A5 (enExample) 2006-03-23

Family

ID=28041882

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003575909A Pending JP2005526076A (ja) 2002-03-13 2003-03-13 Mek阻害剤としてのn3アルキル化ベンズイミダゾール誘導体

Country Status (18)

Country Link
US (2) US20030216460A1 (enExample)
EP (1) EP1482944A4 (enExample)
JP (1) JP2005526076A (enExample)
KR (1) KR20040098013A (enExample)
CN (1) CN1652792A (enExample)
AR (1) AR038972A1 (enExample)
AU (1) AU2003220202A1 (enExample)
CA (1) CA2478534A1 (enExample)
CO (1) CO5611145A2 (enExample)
DO (1) DOP2003000614A (enExample)
IL (1) IL163996A0 (enExample)
MX (1) MXPA04008894A (enExample)
PA (1) PA8569201A1 (enExample)
PL (1) PL378635A1 (enExample)
RU (1) RU2300528C2 (enExample)
TW (1) TW200406203A (enExample)
UA (1) UA76837C2 (enExample)
WO (1) WO2003077855A2 (enExample)

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JP5311673B2 (ja) 2006-12-14 2013-10-09 エグゼリクシス, インコーポレイテッド Mek阻害剤の使用方法
JO2985B1 (ar) 2006-12-20 2016-09-05 Takeda Pharmaceuticals Co مثبطات كينازmapk/erk
WO2008157179A2 (en) 2007-06-12 2008-12-24 Genentech, Inc. N-substituted azaindoles and methods of use
US9409886B2 (en) 2007-07-05 2016-08-09 Array Biopharma Inc. Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
AR067413A1 (es) 2007-07-05 2009-10-07 Genentech Inc Compuestos heterociclicos que contienen ciclopenta[d]pirimidina inhibidores de proteinquinasas akt, composiciones farmaceuticas que los contienen, metodo de preparacion y uso de las mismas para el tratamiento de enfermedades hiperproliferativas, tales como cancer
US8846683B2 (en) 2007-07-05 2014-09-30 Array Biopharma, Inc. Pyrimidyl cyclopentanes as Akt protein kinase inhibitors
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GB0714384D0 (en) 2007-07-23 2007-09-05 Ucb Pharma Sa theraputic agents
CA2705452C (en) 2007-11-12 2016-05-31 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors
PL2231662T3 (pl) 2007-12-19 2011-11-30 Genentech Inc 8-anilinoimidazopirydyny oraz ich zastosowanie jako czynników przeciwnowotworowych i/lub przeciwzapalnych
EP2690101B1 (en) 2007-12-19 2015-06-24 Genentech, Inc. 5-Anilinoimidazopyridines and Methods of Use
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MX2010007546A (es) 2008-01-09 2010-09-30 Array Biopharma Inc Pirimidil ciclopentanos hidroxilados en forma de inhibidores de akt proteína quinasa.
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UA107183C2 (uk) 2008-08-04 2014-12-10 Феніламіно-ізонікотинамідні сполуки, їх застосування, фармацевтична композиція, що їх містить, та спосіб лікування гіперпроліферативних захворювань
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CN103038364A (zh) 2010-03-09 2013-04-10 达纳-法伯癌症研究所公司 诊断和治疗具有或发展对于第一种癌症治疗的抗性的患者中的癌症的方法
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