TR201900306T4 - Mek inhibitörlerini kullanma yöntemleri. - Google Patents

Mek inhibitörlerini kullanma yöntemleri. Download PDF

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Publication number
TR201900306T4
TR201900306T4 TR2019/00306T TR201900306T TR201900306T4 TR 201900306 T4 TR201900306 T4 TR 201900306T4 TR 2019/00306 T TR2019/00306 T TR 2019/00306T TR 201900306 T TR201900306 T TR 201900306T TR 201900306 T4 TR201900306 T4 TR 201900306T4
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TR
Turkey
Prior art keywords
methods
mek inhibitors
solvate
administering
compound
Prior art date
Application number
TR2019/00306T
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English (en)
Inventor
Lamb Peter
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of TR201900306T4 publication Critical patent/TR201900306T4/tr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Mevcut buluş, diğer kanser tedavileri ile kombinasyon halinde, Formül I'in bir bileşiğini veya bunun farmasötik olarak kabul edilebilir bir tuzunu veya solvatını uygulayarak kanseri tedavi etme yöntemleri sağlar.
TR2019/00306T 2006-12-14 2007-12-14 Mek inhibitörlerini kullanma yöntemleri. TR201900306T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87541206P 2006-12-14 2006-12-14

Publications (1)

Publication Number Publication Date
TR201900306T4 true TR201900306T4 (tr) 2019-02-21

Family

ID=39322626

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/00306T TR201900306T4 (tr) 2006-12-14 2007-12-14 Mek inhibitörlerini kullanma yöntemleri.

Country Status (11)

Country Link
US (1) US7999006B2 (tr)
EP (1) EP2101759B1 (tr)
JP (2) JP5311673B2 (tr)
CN (3) CN111643496A (tr)
AU (1) AU2007334402B2 (tr)
CA (1) CA2671982C (tr)
ES (1) ES2703723T3 (tr)
HK (1) HK1218256A1 (tr)
PL (1) PL2101759T3 (tr)
TR (1) TR201900306T4 (tr)
WO (1) WO2008076415A1 (tr)

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JP2010513288A (ja) 2010-04-30
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US20080166359A1 (en) 2008-07-10
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CA2671982C (en) 2016-01-26
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