PL378635A1 - N3 alkilowane pochodne benzoimidazolu jako inhibitory MEK - Google Patents

N3 alkilowane pochodne benzoimidazolu jako inhibitory MEK

Info

Publication number
PL378635A1
PL378635A1 PL378635A PL37863503A PL378635A1 PL 378635 A1 PL378635 A1 PL 378635A1 PL 378635 A PL378635 A PL 378635A PL 37863503 A PL37863503 A PL 37863503A PL 378635 A1 PL378635 A1 PL 378635A1
Authority
PL
Poland
Prior art keywords
benzimidazole derivatives
mek inhibitors
alkylated benzimidazole
alkylated
mek
Prior art date
Application number
PL378635A
Other languages
English (en)
Inventor
Eli M. Wallace
Joseph P. Lyssikatos
Brian T. Hurley
Allison L. Marlow
Original Assignee
Array Biopharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma, Inc. filed Critical Array Biopharma, Inc.
Publication of PL378635A1 publication Critical patent/PL378635A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL378635A 2002-03-13 2003-03-13 N3 alkilowane pochodne benzoimidazolu jako inhibitory MEK PL378635A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36416402P 2002-03-13 2002-03-13

Publications (1)

Publication Number Publication Date
PL378635A1 true PL378635A1 (pl) 2006-05-15

Family

ID=28041882

Family Applications (1)

Application Number Title Priority Date Filing Date
PL378635A PL378635A1 (pl) 2002-03-13 2003-03-13 N3 alkilowane pochodne benzoimidazolu jako inhibitory MEK

Country Status (18)

Country Link
US (2) US20030216460A1 (pl)
EP (1) EP1482944A4 (pl)
JP (1) JP2005526076A (pl)
KR (1) KR20040098013A (pl)
CN (1) CN1652792A (pl)
AR (1) AR038972A1 (pl)
AU (1) AU2003220202A1 (pl)
CA (1) CA2478534A1 (pl)
CO (1) CO5611145A2 (pl)
DO (1) DOP2003000614A (pl)
IL (1) IL163996A0 (pl)
MX (1) MXPA04008894A (pl)
PA (1) PA8569201A1 (pl)
PL (1) PL378635A1 (pl)
RU (1) RU2300528C2 (pl)
TW (1) TW200406203A (pl)
UA (1) UA76837C2 (pl)
WO (1) WO2003077855A2 (pl)

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Also Published As

Publication number Publication date
CO5611145A2 (es) 2006-02-28
EP1482944A4 (en) 2006-04-19
PA8569201A1 (es) 2004-05-21
CN1652792A (zh) 2005-08-10
MXPA04008894A (es) 2005-06-20
WO2003077855A2 (en) 2003-09-25
AR038972A1 (es) 2005-02-02
UA76837C2 (uk) 2006-09-15
CA2478534A1 (en) 2003-09-25
AU2003220202A1 (en) 2003-09-29
JP2005526076A (ja) 2005-09-02
RU2004127925A (ru) 2005-05-27
RU2300528C2 (ru) 2007-06-10
IL163996A0 (en) 2005-12-18
DOP2003000614A (es) 2009-09-30
EP1482944A2 (en) 2004-12-08
US20060106225A1 (en) 2006-05-18
US20030216460A1 (en) 2003-11-20
WO2003077855A3 (en) 2004-03-04
KR20040098013A (ko) 2004-11-18
TW200406203A (en) 2004-05-01

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