JP2005508505A5 - - Google Patents

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JP2005508505A5
JP2005508505A5 JP2003542649A JP2003542649A JP2005508505A5 JP 2005508505 A5 JP2005508505 A5 JP 2005508505A5 JP 2003542649 A JP2003542649 A JP 2003542649A JP 2003542649 A JP2003542649 A JP 2003542649A JP 2005508505 A5 JP2005508505 A5 JP 2005508505A5
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rna
panel
data set
gene expression
profile data
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JP2003542649A
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JP2005508505A (ja
JP5236856B2 (ja
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Priority claimed from PCT/US2002/036084 external-priority patent/WO2003040404A1/en
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JP2003542649A 2001-11-09 2002-11-08 遺伝子発現プロファイルを用いる病気の同定、観測及び治療及び生物学的状態の同定 Expired - Lifetime JP5236856B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US34821301P 2001-11-09 2001-11-09
US60/348,213 2001-11-09
US34088101P 2001-12-07 2001-12-07
US60/340,881 2001-12-07
US36963302P 2002-04-03 2002-04-03
US60/369,633 2002-04-03
US37699702P 2002-04-30 2002-04-30
US60/376,997 2002-04-30
PCT/US2002/036084 WO2003040404A1 (en) 2001-11-09 2002-11-08 Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles

Related Child Applications (1)

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JP2010254661A Division JP2011067214A (ja) 2001-11-09 2010-11-15 遺伝子発現プロファイルを用いる病気の同定、観測及び治療及び生物学的状態の同定

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JP2005508505A JP2005508505A (ja) 2005-03-31
JP2005508505A5 true JP2005508505A5 (enExample) 2013-04-18
JP5236856B2 JP5236856B2 (ja) 2013-07-17

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JP2003542649A Expired - Lifetime JP5236856B2 (ja) 2001-11-09 2002-11-08 遺伝子発現プロファイルを用いる病気の同定、観測及び治療及び生物学的状態の同定
JP2010254661A Withdrawn JP2011067214A (ja) 2001-11-09 2010-11-15 遺伝子発現プロファイルを用いる病気の同定、観測及び治療及び生物学的状態の同定

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JP2010254661A Withdrawn JP2011067214A (ja) 2001-11-09 2010-11-15 遺伝子発現プロファイルを用いる病気の同定、観測及び治療及び生物学的状態の同定

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US (4) US6964850B2 (enExample)
EP (1) EP1451340B1 (enExample)
JP (2) JP5236856B2 (enExample)
KR (1) KR20040064275A (enExample)
CN (2) CN1612936A (enExample)
CA (1) CA2466502A1 (enExample)
WO (1) WO2003040404A1 (enExample)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7473528B2 (en) 1999-01-06 2009-01-06 Genenews Inc. Method for the detection of Chagas disease related gene transcripts in blood
US6960439B2 (en) 1999-06-28 2005-11-01 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
US7026121B1 (en) 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7235358B2 (en) * 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US6964850B2 (en) 2001-11-09 2005-11-15 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
DE60327737D1 (de) * 2002-01-22 2009-07-09 Biomatera Inc Verfahren zur trocknung von biologisch abbaubaren polymeren
AU2003299503A1 (en) * 2002-05-16 2004-06-15 Vanderbilt University Method for predicting autoimmune diseases
MXPA05005073A (es) * 2002-11-12 2005-11-17 Becton Dickinson Co Diagnostico de la sepsis o sirs usando perfiles de biomarcadores.
MXPA05005072A (es) 2002-11-12 2005-07-22 Becton Dickinson Co Diagnostico de la sepsis o sirs usando perfiles de biomarcadores.
CA2505921A1 (en) 2002-11-12 2004-05-27 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
CA2506066A1 (en) * 2002-11-15 2004-06-03 Genomic Health, Inc. Gene expression profiling of egfr positive cancer
AU2003303238B2 (en) * 2002-12-19 2010-07-22 Life Technologies Corporation Identification, monitoring and treatment of infectious disease and characterization of inflammatory conditions related to infectious disease using gene expression profiles
US20040231909A1 (en) * 2003-01-15 2004-11-25 Tai-Yang Luh Motorized vehicle having forward and backward differential structure
WO2004071572A2 (en) * 2003-02-06 2004-08-26 Genomic Health, Inc. Gene expression markers for response to egfr inhibitor drugs
US20080014579A1 (en) * 2003-02-11 2008-01-17 Affymetrix, Inc. Gene expression profiling in colon cancers
CA2516553C (en) * 2003-02-20 2013-04-16 Genomic Health, Inc. Use of intronic rna to measure gene expression
US7892745B2 (en) 2003-04-24 2011-02-22 Xdx, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
CA2527321A1 (en) * 2003-05-30 2004-12-23 Genomic Health, Inc. Gene expression markers for response to egfr inhibitor drugs
WO2005039382A2 (en) * 2003-06-24 2005-05-06 Genomic Health Prediction of likelihood of cancer recurrence
WO2005007892A1 (en) * 2003-07-03 2005-01-27 Gentron, Llc Methods and systems for diagnosis of non-cenral nervous system (cns) diseases in cns samples
EP1644858B1 (en) 2003-07-10 2017-12-06 Genomic Health, Inc. Expression profile algorithm and test for cancer prognosis
EP2128270B1 (en) 2003-08-08 2012-10-03 Genenews Inc. Osteoarthritis biomarkers and uses thereof
AU2004284434A1 (en) * 2003-10-16 2005-05-06 Genomic Health, Inc. qRT-PCR assay system for gene expression profiling
JP4718490B2 (ja) * 2003-12-23 2011-07-06 ジェノミック ヘルス, インコーポレイテッド フラグメント化rnaの全般的増幅
CA2848463A1 (en) 2004-04-09 2005-10-27 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
US7645575B2 (en) * 2004-09-08 2010-01-12 Xdx, Inc. Genes useful for diagnosing and monitoring inflammation related disorders
CA3061785A1 (en) 2004-11-05 2006-05-18 Genomic Health, Inc. Predicting response to chemotherapy using gene expression markers
JP4939425B2 (ja) * 2004-11-05 2012-05-23 ジェノミック ヘルス, インコーポレイテッド 乳癌の治療反応の予後および予測の分子指標
US20060157647A1 (en) * 2005-01-18 2006-07-20 Becton, Dickinson And Company Multidimensional liquid chromatography/spectrometry
BRPI0609302A2 (pt) 2005-04-15 2011-10-11 Becton Dickinson Co métodos para prever o desenvolvimento de sepse e para diagnosticar sepse em um indivìduo a ser testado, microarranjo, kit para prever o desenvolvimento de sepse em um indivìduo a ser testado, produto de programa de computador, computador, sistema de computador para determinar se um indivìduo é susceptìvel de desenvolver sepse, sinal digital embutido em uma onda portadora, e, interface gráfica de usuário para determinar se um indivìduo é susceptìvel de desenvolver sepse
WO2006133399A1 (en) 2005-06-08 2006-12-14 Hitachi Chemical Research Center, Inc. METHOD FOR PREDICTING IMMUNE RESPONSE TO NEOPLASTIC DISEASE BASED ON mRNA EXPRESSION PROFILE IN NEOPLASTIC CELLS AND STIMULATED LEUKOCYTES
JP5024583B2 (ja) * 2005-09-14 2012-09-12 ソニー株式会社 情報処理装置および情報処理方法、情報処理システム、プログラム、並びに、記録媒体
KR20090003178A (ko) * 2006-01-11 2009-01-09 게노믹 헬쓰, 인코포레이티드 직장결장암 예후에 대한 유전자 발현 마커
WO2007123772A2 (en) 2006-03-31 2007-11-01 Genomic Health, Inc. Genes involved in estrogen metabolism
WO2009070442A2 (en) 2007-11-14 2009-06-04 Hitachi Chemical Co. Ltd. Fc receptor-mediated tumor necrosis factor superfamily mrna expression in peripheral blood leukocytes
ATE518011T1 (de) 2006-04-07 2011-08-15 Hitachi Chemical Co Ltd Erhöhte expression von t- zellenrezeptorvermittelter tumornekrosefaktorsuperfamilie und chemokin-mrna in peripheren blut leukozyten bei patienten mit morbus& xa;crohn
EP2021988A2 (en) * 2006-05-10 2009-02-11 Koninklijke Philips Electronics N.V. Transforming measurement data for classification learning
CA2652239A1 (en) * 2006-05-16 2007-11-29 Source Mdx Assessment of effect of an agent on a human biological condition using rodent gene expression panels
JP5470848B2 (ja) * 2006-08-04 2014-04-16 味の素株式会社 肺癌の評価方法、肺癌評価装置、肺癌評価方法、肺癌評価システム、肺癌評価プログラム、記録媒体、および、情報通信端末装置
WO2008021431A2 (en) 2006-08-14 2008-02-21 Xdx, Inc. Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders
EP2102367A2 (en) 2006-11-09 2009-09-23 XDX, Inc. Methods for diagnosing and monitoring the status of systemic lupus erythematosus
US20090104605A1 (en) * 2006-12-14 2009-04-23 Gary Siuzdak Diagnosis of sepsis
EP2103940A4 (en) * 2006-12-21 2013-04-24 Ajinomoto Kk METHOD, APPARATUS, METHOD, SYSTEM AND SOFTWARE FOR ASSESSING BREAST CANCER, AND RECORDING MEDIUM
JPWO2008075664A1 (ja) * 2006-12-21 2010-04-15 味の素株式会社 癌の評価方法、ならびに癌評価装置、癌評価方法、癌評価システム、癌評価プログラムおよび記録媒体
EP2096439A4 (en) 2006-12-21 2011-01-05 Ajinomoto Kk METHOD, APPARATUS, METHOD, SYSTEM AND SOFTWARE FOR EVALUATING COLORECTAL CANCER, AND RECORDING MEDIUM
US20090117562A1 (en) 2007-04-09 2009-05-07 Valerie Wailin Hu Method and kit for diagnosing Autism using gene expression profiling
ES2417148T3 (es) 2007-06-08 2013-08-06 Genentech, Inc. Marcadores de expresión génica de la resistencia tumoral al tratamiento con inhibidor de HER2
US9551033B2 (en) 2007-06-08 2017-01-24 Genentech, Inc. Gene expression markers of tumor resistance to HER2 inhibitor treatment
WO2008154532A1 (en) * 2007-06-11 2008-12-18 California Pacific Medical Center Method and kit for dynamic gene expression monitoring
US8068994B2 (en) * 2007-07-27 2011-11-29 Wayne State University Method for analyzing biological networks
JP2011511271A (ja) * 2008-01-25 2011-04-07 サイトテック ラブズ リミテッド ライアビリティ カンパニー 腫瘍原性、腫瘍進行、および処置効率の査定のためのアッセイシステム
KR101272207B1 (ko) * 2008-02-06 2013-06-07 아지노모토 가부시키가이샤 위암의 평가 방법, 및 위암 평가 장치, 위암 평가 방법, 위암 평가 시스템, 위암 평가 프로그램 및 기록 매체
WO2009123737A2 (en) 2008-04-03 2009-10-08 Becton, Dickinson And Company Advanced detection of sepsis
US7776522B2 (en) * 2008-04-24 2010-08-17 Becton, Dickinson And Company Methods for diagnosing oncogenic human papillomavirus (HPV)
EP2294216A4 (en) 2008-05-14 2011-11-23 Dermtech Int DIAGNOSIS OF MELANOMA AND SOLAR LENTIGO BY ANALYSIS OF NUCLEIC ACIDS
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
JP5754136B2 (ja) * 2008-06-20 2015-07-29 味の素株式会社 女性生殖器癌の評価方法、女性生殖器癌評価装置、女性生殖器癌評価方法、女性生殖器癌評価プログラム、記録媒体、女性生殖器癌評価システム、および情報通信端末装置
JP5754137B2 (ja) 2008-06-20 2015-07-29 味の素株式会社 前立腺癌の評価方法、前立腺癌評価装置、前立腺癌評価方法、前立腺癌評価プログラム、記録媒体、前立腺癌評価システム、および情報通信端末装置
EP2331707A4 (en) * 2008-08-28 2012-06-06 Dermtech Int DETERMINATION OF THE AGING RANGE OF SKIN SAMPLE
US8748103B2 (en) 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US9528160B2 (en) 2008-11-07 2016-12-27 Adaptive Biotechnolgies Corp. Rare clonotypes and uses thereof
US9365901B2 (en) 2008-11-07 2016-06-14 Adaptive Biotechnologies Corp. Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
US8628927B2 (en) 2008-11-07 2014-01-14 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US9506119B2 (en) 2008-11-07 2016-11-29 Adaptive Biotechnologies Corp. Method of sequence determination using sequence tags
US8691510B2 (en) 2008-11-07 2014-04-08 Sequenta, Inc. Sequence analysis of complex amplicons
GB2483810B (en) 2008-11-07 2012-09-05 Sequenta Inc Methods for correlating clonotypes with diseases in a population
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
PT2387627E (pt) 2009-01-15 2016-06-03 Adaptive Biotechnologies Corp Determinação do perfil de imunidade adaptativa e métodos de geração de anticorpos monoclonais
WO2010127322A1 (en) * 2009-05-01 2010-11-04 Genomic Health Inc. Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy
JP2012531202A (ja) 2009-06-25 2012-12-10 フレッド ハチンソン キャンサー リサーチ センター 適応免疫を測定する方法
US9043160B1 (en) 2009-11-09 2015-05-26 Sequenta, Inc. Method of determining clonotypes and clonotype profiles
CN103237901B (zh) 2010-03-01 2016-08-03 卡里斯生命科学瑞士控股有限责任公司 用于治疗诊断的生物标志物
CA2795776A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers for disease
JP5755326B2 (ja) 2010-06-11 2015-07-29 日立化成株式会社 腎機能の特徴を決定する方法
WO2011156734A2 (en) * 2010-06-11 2011-12-15 Hitachi Chemical Co., Ltd. Method of characterizing vascular diseases
MX338883B (es) 2010-07-27 2016-05-04 Genomic Health Inc Metodo para usar expresion de gen para determinar el pronostico de cancer de prostata.
WO2012021714A2 (en) * 2010-08-12 2012-02-16 William Marsh Rice University Biomarker signatures for wellness testing
US10011876B2 (en) 2010-11-23 2018-07-03 Krisani Biosciences Pvt. Ltd Method and system for prognosis and treatment of diseases using portfolio of genes
US20140032125A1 (en) * 2011-02-12 2014-01-30 Siemens Healthcare Diagnostics Inc. Environment and Method for Rapid Analysis of Genomic Sequence Data
WO2012170037A1 (en) 2011-06-10 2012-12-13 Hitachi Chemical Co., Ltd. Vesicle capturing devices and methods for using same
US10385475B2 (en) 2011-09-12 2019-08-20 Adaptive Biotechnologies Corp. Random array sequencing of low-complexity libraries
EP2768982A4 (en) 2011-10-21 2015-06-03 Adaptive Biotechnologies Corp QUANTIFICATION OF ADAPTIVE IMMUNOCELL GENOMES IN A COMPLEX MIX OF CELLS
ES2926726T3 (es) 2011-11-14 2022-10-27 Aushon Biosystems Inc Sistemas y métodos para mejorar la consistencia del rendimiento de un ensayo
AU2012347460B2 (en) 2011-12-09 2017-05-25 Adaptive Biotechnologies Corporation Diagnosis of lymphoid malignancies and minimal residual disease detection
US9499865B2 (en) 2011-12-13 2016-11-22 Adaptive Biotechnologies Corp. Detection and measurement of tissue-infiltrating lymphocytes
SG11201404390WA (en) 2012-01-31 2014-08-28 Genomic Health Inc Gene expression profile algorithm and test for determining prognosis of prostate cancer
JP6302847B2 (ja) 2012-03-05 2018-03-28 アダプティヴ バイオテクノロジーズ コーポレーション 頻度が一致したサブユニットからの、対をなす免疫受容体鎖の決定
ES2711156T3 (es) 2012-05-08 2019-04-30 Adaptive Biotechnologies Corp Método para medir y calibrar el sesgo de amplificación en reacciones de PCR multiplexadas
JP6219934B2 (ja) 2012-05-22 2017-10-25 バーグ エルエルシー 薬物誘発毒性マーカーを同定するための照合による細胞に基づくアッセイ
FR2993282B1 (fr) * 2012-07-13 2017-11-10 Expanscience Lab Procede d'identification de marqueurs moleculaires de la peau d'enfant
EP2895861A4 (en) * 2012-09-12 2016-06-22 Berg Llc USE OF MARKERS FOR THE IDENTIFICATION OF CARDIOTOXIC AGENTS
WO2014043581A1 (en) * 2012-09-14 2014-03-20 Life Technologies Corporation Methods and systems for a digital pcr experiment designer
EP2904111B1 (en) 2012-10-01 2017-12-06 Adaptive Biotechnologies Corporation Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization
EP3639841B1 (en) 2013-03-27 2023-09-06 Cedars-Sinai Medical Center Treating fibrosis by inhibiting tl1a
DE212013000295U1 (de) 2013-05-06 2016-02-02 Hitachi Chemical Co. America, Ltd. Vorrichtungen zum Einfangen von Zielmolekülen
US9708657B2 (en) 2013-07-01 2017-07-18 Adaptive Biotechnologies Corp. Method for generating clonotype profiles using sequence tags
EP3022295A4 (en) 2013-07-19 2017-03-01 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
JP6703479B2 (ja) 2013-12-16 2020-06-03 フィリップ モリス プロダクツ エス アー 個人の喫煙ステータスを予測するためのシステムおよび方法
CA2935720A1 (en) * 2014-01-16 2015-07-23 Illumina, Inc. Gene expression panel for prognosis of prostate cancer recurrence
US11578373B2 (en) 2019-03-26 2023-02-14 Dermtech, Inc. Gene classifiers and uses thereof in skin cancers
US20170292149A1 (en) 2014-03-05 2017-10-12 Adaptive Biotechnologies Corporation Methods using randomer-containing synthetic molecules
US10066265B2 (en) 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
ES2777529T3 (es) 2014-04-17 2020-08-05 Adaptive Biotechnologies Corp Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células
EP3172564A4 (en) * 2014-07-18 2018-06-27 Genova Diagnostics, Inc. Use of an evidence-based, translational algorithm to, inter alia, assess biomarkers
WO2016069886A1 (en) 2014-10-29 2016-05-06 Adaptive Biotechnologies Corporation Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
US10266895B2 (en) 2014-11-05 2019-04-23 Hitachi Chemical Company Ltd. Exosomes and microvesicles in intestinal luminal fluids and stool and use of same for the assessment of inflammatory bowel disease
WO2016077537A1 (en) 2014-11-12 2016-05-19 Hitachi Chemical Co., Ltd. Method and device for diagnosing organ injury
US10246701B2 (en) 2014-11-14 2019-04-02 Adaptive Biotechnologies Corp. Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
CA2968543C (en) 2014-11-25 2024-04-02 Adaptive Biotechnologies Corporation Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
WO2016138122A1 (en) 2015-02-24 2016-09-01 Adaptive Biotechnologies Corp. Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
WO2016161273A1 (en) 2015-04-01 2016-10-06 Adaptive Biotechnologies Corp. Method of identifying human compatible t cell receptors specific for an antigenic target
CN108271422A (zh) 2015-06-25 2018-07-10 株式会社国际电气通信基础技术研究所 基于器官间串扰系统的预测装置及预测程序
JP6867959B2 (ja) * 2015-07-13 2021-05-12 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 病院環境における感染の追跡
WO2017040520A1 (en) 2015-08-31 2017-03-09 Hitachi Chemical Co., Ltd. Molecular methods for assessing urothelial disease
CN105279397B (zh) * 2015-10-26 2017-12-19 华东交通大学 一种识别蛋白质相互作用网络中关键蛋白质的方法
KR101795662B1 (ko) * 2015-11-19 2017-11-13 연세대학교 산학협력단 대사 이상 질환 진단 장치 및 그 방법
JP7082945B2 (ja) 2016-03-17 2022-06-09 シーダーズ―シナイ メディカル センター Rnaset2により炎症性腸疾患を診断する方法
JP6432962B2 (ja) 2016-03-29 2018-12-05 株式会社国際電気通信基礎技術研究所 腎機能低下、慢性腎疾患及び腎不全からなる群から選択される少なくとも一種の疾患を予防、又は治療するための有効成分の候補物質のスクリーニング方法
JP6332780B2 (ja) 2016-03-29 2018-05-30 株式会社国際電気通信基礎技術研究所 医薬組成物又は食品組成物、及び有効成分の体内での効果の評価方法
US10607720B2 (en) 2016-05-11 2020-03-31 International Business Machines Corporation Associating gene expression data with a disease name
US10428325B1 (en) 2016-09-21 2019-10-01 Adaptive Biotechnologies Corporation Identification of antigen-specific B cell receptors
CN106709267A (zh) * 2017-01-25 2017-05-24 武汉贝纳科技服务有限公司 数据获取方法及装置
CN107058521B (zh) * 2017-03-17 2019-12-27 中国科学院北京基因组研究所 一种检测人体免疫状态的检测系统
JPWO2019066044A1 (ja) 2017-09-29 2020-12-10 ファーマバイオ株式会社 標準化発現量を利用した再生医療製品等の品質管理の手法
US11254980B1 (en) 2017-11-29 2022-02-22 Adaptive Biotechnologies Corporation Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
US11976332B2 (en) 2018-02-14 2024-05-07 Dermtech, Inc. Gene classifiers and uses thereof in non-melanoma skin cancers
EP3762506A4 (en) * 2018-02-21 2022-03-23 Edifice Health, Inc. METHOD OF MEASURING AGING DUE TO CHRONIC SYSTEMIC INFLAMMATION
EP3765853B1 (en) * 2018-03-13 2024-05-01 Creatv Microtech, Inc. Methods for monitoring treatment response and disease progression in subjects using circulating cells
WO2019193241A1 (en) * 2018-04-03 2019-10-10 Nokia Technologies Oy Use of band combination index for definition of carrier aggregation configurations
KR102170726B1 (ko) * 2018-10-04 2020-10-27 사회복지법인 삼성생명공익재단 바이오마커의 선별 방법 및 이를 이용한 암의 진단을 위한 정보제공방법
KR102875526B1 (ko) * 2019-03-26 2025-10-22 제이에프이 스틸 가부시키가이샤 프로세스 상태 감시 장치 및 프로세스 상태 감시 방법
US20230003719A1 (en) * 2019-12-13 2023-01-05 Janssen Biotech, Inc. Materials and methods for inflammatory molecular markers
US20250230502A1 (en) * 2022-03-30 2025-07-17 National Cancer Center Ifi16 mutant gene as a marker for risk prediction, diagnosis or prognosis of chronic liver disease and uses thereof
CN118298911B (zh) * 2024-04-12 2024-11-22 中山大学孙逸仙纪念医院 一种多部位慢性疼痛潜在治疗靶点确定系统

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5580722A (en) * 1989-07-18 1996-12-03 Oncogene Science, Inc. Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease
US5569601A (en) * 1990-12-07 1996-10-29 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Human dopamine receptor and its uses
US6114114A (en) 1992-07-17 2000-09-05 Incyte Pharmaceuticals, Inc. Comparative gene transcript analysis
JP3509100B2 (ja) * 1993-01-21 2004-03-22 プレジデント アンド フェローズ オブ ハーバード カレッジ 哺乳動物のストレスプロモーターを利用する化合物の毒性測定方法および診断用キット
US5643765A (en) 1993-04-06 1997-07-01 University Of Rochester Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
DK0695361T4 (da) * 1993-04-21 2010-03-22 Univ Edinburgh Ekspression af heterologe gener ifølge en målekspressionsprofil
US6309823B1 (en) * 1993-10-26 2001-10-30 Affymetrix, Inc. Arrays of nucleic acid probes for analyzing biotransformation genes and methods of using the same
US7625697B2 (en) * 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US5506145A (en) * 1994-12-02 1996-04-09 Bull; Brian S. Determination of an individual's inflammation index from whole blood fibrinogen and hematocrit or hemoglobin measurements
US5693646A (en) * 1994-12-22 1997-12-02 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
US5968770A (en) * 1995-02-10 1999-10-19 Millennium Pharmaceuticals, Inc. Compositions and methods for the treatment and diagnosis of cardiovascular disease using rchd523 as a target
US6022683A (en) * 1996-12-16 2000-02-08 Nova Molecular Inc. Methods for assessing the prognosis of a patient with a neurodegenerative disease
US5866330A (en) * 1995-09-12 1999-02-02 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
US5922184A (en) 1997-07-21 1999-07-13 Bio-Rad Laboratories, Inc. Computer-directed detection of paraproteins
FR2775984B1 (fr) 1998-03-11 2006-09-15 Bioscreen Therapeutics Sa Criblage differentiel qualitatif
EP0910666B1 (en) 1996-05-02 2006-08-09 Applera Corporation Quantitation of rna transcripts using genomic dna as the internal amplification competitor
US5955269A (en) * 1996-06-20 1999-09-21 Rutgers, The State University Of New Jersey Methods of screening foods for nutraceuticals
US6146828A (en) * 1996-08-14 2000-11-14 Exact Laboratories, Inc. Methods for detecting differences in RNA expression levels and uses therefor
EP0960214A4 (en) 1996-12-06 2004-08-04 Urocor Inc Diagnosis of disease status on HAnd from mRNA profiles
JPH10261029A (ja) 1996-12-16 1998-09-29 Nissho Corp アルツハイマー病生涯罹病性の予測システム
US5968784A (en) * 1997-01-15 1999-10-19 Chugai Pharmaceutical Co., Ltd. Method for analyzing quantitative expression of genes
US6165709A (en) * 1997-02-28 2000-12-26 Fred Hutchinson Cancer Research Center Methods for drug target screening
US5994076A (en) * 1997-05-21 1999-11-30 Clontech Laboratories, Inc. Methods of assaying differential expression
AU9217198A (en) 1997-09-03 1999-03-22 Oncormed Method for predicting prognosis and treatment response for genetically based abnormalities
DE69829402T2 (de) 1997-10-31 2006-04-13 Affymetrix, Inc. (a Delaware Corp.), Santa Clara Expressionsprofile in adulten und fötalen organen
JP3784162B2 (ja) 1998-01-14 2006-06-07 株式会社日立製作所 Dna断片分析法
PT1068528E (pt) 1998-02-25 2006-12-29 Us Gov Health & Human Serv Método e aparato para reparar uma série para o estabelecimento rápido de perfis moleculares
JP2002512046A (ja) 1998-04-23 2002-04-23 ジェネンテック・インコーポレーテッド 遺伝子発現の定量的分析
EP1075485A4 (en) 1998-05-05 2004-12-15 Gene Logic Inc METHOD FOR STUDYING MODIFICATIONS OF GENE EXPRESSION IN T CELLS
US6232065B1 (en) * 1998-05-06 2001-05-15 Case Western Reserve University Analysis of gene family expression
US6324479B1 (en) * 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
JP2002514804A (ja) 1998-05-12 2002-05-21 ロゼッタ インファーマティクス, インコーポレーテッド 遺伝子発現分析のための数値化方法、システムおよび装置
US6218122B1 (en) * 1998-06-19 2001-04-17 Rosetta Inpharmatics, Inc. Methods of monitoring disease states and therapies using gene expression profiles
US6132969A (en) * 1998-06-19 2000-10-17 Rosetta Inpharmatics, Inc. Methods for testing biological network models
ATE253126T1 (de) 1998-08-25 2003-11-15 Univ Washington Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
US6185561B1 (en) * 1998-09-17 2001-02-06 Affymetrix, Inc. Method and apparatus for providing and expression data mining database
US6245517B1 (en) * 1998-09-29 2001-06-12 The United States Of America As Represented By The Department Of Health And Human Services Ratio-based decisions and the quantitative analysis of cDNA micro-array images
US20010055760A1 (en) 1998-10-13 2001-12-27 Alex Chenchik Nucleic acid arrays
US6203987B1 (en) * 1998-10-27 2001-03-20 Rosetta Inpharmatics, Inc. Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
AU777624B2 (en) 1998-11-05 2004-10-21 Ortho-Mcneil Pharmaceutical, Inc. Method for generating gene expression profiles
US6222093B1 (en) * 1998-12-28 2001-04-24 Rosetta Inpharmatics, Inc. Methods for determining therapeutic index from gene expression profiles
WO2000058728A1 (fr) * 1999-03-26 2000-10-05 Uno, Akitane Moyen d'examen precoce de tumeur maligne
WO2000066259A1 (en) * 1999-05-05 2000-11-09 Ut-Battelle, Llc Method and apparatus for combinatorial chemistry
DK1630709T3 (da) 1999-05-25 2009-12-07 Aventis Pharma Inc Matematisk analyse til estimering af ændringer i niveauet af reportergen
DK1198585T3 (da) * 1999-06-28 2007-10-15 Source Precision Medicine Inc Fremgangsmåde til karakterisering af en biologisk tilstand ved anvendelse af kalibrerede genudtrykkelsesprofiler
AU6533700A (en) 1999-08-09 2001-03-05 Affymetrix, Inc. Methods of gene expression monitoring
CA2381777C (en) 1999-08-12 2011-10-04 Wisconsin Alumni Research Foundation Identification of genetic markers of biological age and metabolism
WO2001020998A1 (en) 1999-09-24 2001-03-29 Linden Technologies, Inc. Drug discovery using gene expression profiling
US6505125B1 (en) 1999-09-28 2003-01-07 Affymetrix, Inc. Methods and computer software products for multiple probe gene expression analysis
AU1179001A (en) 1999-10-13 2001-04-23 Plant Research International B.V. Method for detecting differences in gene expression between wild type plants andnewly developed plants
US6607885B1 (en) 1999-10-15 2003-08-19 E. I. Du Pont De Nemours And Company Method for high-density microarray medicated gene expression profiling
EP1287162A2 (en) 1999-10-21 2003-03-05 Case Western Reserve University Gene expression profiling of inflammatory bowel disease
MXPA02004241A (es) 1999-10-26 2002-10-17 Digital Gene Tech Inc Regulacion de la expresion de genes por agentes neurolepticos.
AU1466001A (en) 1999-11-05 2001-05-14 Phase-1 Molecular Toxicology Methods of determining individual hypersensitivity to an agent
US6248535B1 (en) 1999-12-20 2001-06-19 University Of Southern California Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
WO2001075162A2 (en) * 2000-03-31 2001-10-11 University Of Louisville Research Foundation, Inc. Microarrays to screen regulatory genes
US7384736B2 (en) * 2001-09-06 2008-06-10 Decode Genetics Ehf. Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease
US6964850B2 (en) 2001-11-09 2005-11-15 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles

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