KR20040064275A - 유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인 - Google Patents
유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인 Download PDFInfo
- Publication number
- KR20040064275A KR20040064275A KR10-2004-7007103A KR20047007103A KR20040064275A KR 20040064275 A KR20040064275 A KR 20040064275A KR 20047007103 A KR20047007103 A KR 20047007103A KR 20040064275 A KR20040064275 A KR 20040064275A
- Authority
- KR
- South Korea
- Prior art keywords
- data set
- panel
- gene expression
- profile data
- components
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34821301P | 2001-11-09 | 2001-11-09 | |
| US60/348,213 | 2001-11-09 | ||
| US34088101P | 2001-12-07 | 2001-12-07 | |
| US60/340,881 | 2001-12-07 | ||
| US36963302P | 2002-04-03 | 2002-04-03 | |
| US60/369,633 | 2002-04-03 | ||
| US37699702P | 2002-04-30 | 2002-04-30 | |
| US60/376,997 | 2002-04-30 | ||
| PCT/US2002/036084 WO2003040404A1 (en) | 2001-11-09 | 2002-11-08 | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20040064275A true KR20040064275A (ko) | 2004-07-16 |
Family
ID=27502635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR10-2004-7007103A Ceased KR20040064275A (ko) | 2001-11-09 | 2002-11-08 | 유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US6964850B2 (enExample) |
| EP (1) | EP1451340B1 (enExample) |
| JP (2) | JP5236856B2 (enExample) |
| KR (1) | KR20040064275A (enExample) |
| CN (2) | CN1612936A (enExample) |
| CA (1) | CA2466502A1 (enExample) |
| WO (1) | WO2003040404A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017086675A1 (ko) * | 2015-11-19 | 2017-05-26 | 연세대학교 산학협력단 | 대사 이상 질환 진단 장치 및 그 방법 |
| KR20200038660A (ko) * | 2018-10-04 | 2020-04-14 | 사회복지법인 삼성생명공익재단 | 바이오마커의 선별 방법 및 이를 이용한 암의 진단을 위한 정보제공방법 |
Families Citing this family (134)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7473528B2 (en) | 1999-01-06 | 2009-01-06 | Genenews Inc. | Method for the detection of Chagas disease related gene transcripts in blood |
| US6960439B2 (en) | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US6905827B2 (en) | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US7026121B1 (en) | 2001-06-08 | 2006-04-11 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| JP5236856B2 (ja) | 2001-11-09 | 2013-07-17 | ライフ テクノロジーズ コーポレーション | 遺伝子発現プロファイルを用いる病気の同定、観測及び治療及び生物学的状態の同定 |
| WO2003062438A1 (en) * | 2002-01-22 | 2003-07-31 | Biomatera Inc. | Method of drying biodegradable polymers |
| JP2006503587A (ja) * | 2002-05-16 | 2006-02-02 | バンダービルト・ユニバーシティ | 自己免疫疾患の予測方法 |
| MXPA05005073A (es) * | 2002-11-12 | 2005-11-17 | Becton Dickinson Co | Diagnostico de la sepsis o sirs usando perfiles de biomarcadores. |
| CA2505921A1 (en) | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| AU2003291484A1 (en) | 2002-11-12 | 2004-06-03 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| EP1570080A4 (en) | 2002-11-15 | 2006-03-01 | Genomic Health Inc | GENE EXPRESSION PROFILING OF EGFR-POSITIVE CANCER DISEASE |
| JP2006510382A (ja) * | 2002-12-19 | 2006-03-30 | ソース プレシジョン メディスン, インコーポレイテッド | 遺伝子発現プロフィールを用いる、感染症の同定、モニタリング、および処置、ならびに感染症に関連する炎症状態の特徴付け |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| CA2515096A1 (en) * | 2003-02-06 | 2004-08-26 | Genomic Health, Inc. | Gene expression markers for response to egfr inhibitor drugs |
| US20080014579A1 (en) * | 2003-02-11 | 2008-01-17 | Affymetrix, Inc. | Gene expression profiling in colon cancers |
| EP1597391B1 (en) * | 2003-02-20 | 2008-10-29 | Genomic Health, Inc. | Use of intronic rna to measure gene expression |
| US7892745B2 (en) | 2003-04-24 | 2011-02-22 | Xdx, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| WO2004111273A2 (en) * | 2003-05-30 | 2004-12-23 | Genomic Health, Inc. | Gene expression markers for response to egfr inhibitor drugs |
| DK3170906T3 (en) | 2003-06-24 | 2018-11-05 | Genomic Health Inc | PREDICTION OF THE LIKELI REVENUE OF CANCER |
| WO2005007892A1 (en) * | 2003-07-03 | 2005-01-27 | Gentron, Llc | Methods and systems for diagnosis of non-cenral nervous system (cns) diseases in cns samples |
| DK1644858T3 (da) | 2003-07-10 | 2018-01-22 | Genomic Health Inc | Funktionel beklædning med mindst et yderlag og en indermembran. |
| WO2005014795A2 (en) | 2003-08-08 | 2005-02-17 | Genenews Inc. | Osteoarthritis biomarkers and uses thereof |
| AU2004284434A1 (en) * | 2003-10-16 | 2005-05-06 | Genomic Health, Inc. | qRT-PCR assay system for gene expression profiling |
| EP1699936B1 (en) * | 2003-12-23 | 2011-02-09 | Genomic Health, Inc. | Universal amplification of fragmented rna |
| CA2848463A1 (en) | 2004-04-09 | 2005-10-27 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| US7645575B2 (en) | 2004-09-08 | 2010-01-12 | Xdx, Inc. | Genes useful for diagnosing and monitoring inflammation related disorders |
| US7622251B2 (en) * | 2004-11-05 | 2009-11-24 | Genomic Health, Inc. | Molecular indicators of breast cancer prognosis and prediction of treatment response |
| EP1836629B1 (en) | 2004-11-05 | 2020-03-04 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| US20060157647A1 (en) * | 2005-01-18 | 2006-07-20 | Becton, Dickinson And Company | Multidimensional liquid chromatography/spectrometry |
| WO2006113529A2 (en) | 2005-04-15 | 2006-10-26 | Becton, Dickinson And Company | Diagnosis of sepsis |
| ATE510929T1 (de) | 2005-06-08 | 2011-06-15 | Hitachi Chemical Res Ct Inc | Verfahren zur vorhersage einer immunantwort auf eine tumorerkrankung auf der grundlage eines mrna-expressionsprofils in tumorzellen und stimulierten leukozyten |
| JP5024583B2 (ja) * | 2005-09-14 | 2012-09-12 | ソニー株式会社 | 情報処理装置および情報処理方法、情報処理システム、プログラム、並びに、記録媒体 |
| NZ593225A (en) * | 2006-01-11 | 2012-10-26 | Genomic Health Inc | Gene expression markers (CMYC and Ki-67) for colorectal cancer prognosis |
| US7888019B2 (en) | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| EP2005175B1 (en) * | 2006-04-07 | 2011-07-27 | Hitachi Chemical Company, Ltd. | Enhanced t cell receptor-mediated tumor necrosis factor superfamily and chemokine mrna expression in peripheral blood leukocytes in patients with crohn's disease |
| EP2021988A2 (en) * | 2006-05-10 | 2009-02-11 | Koninklijke Philips Electronics N.V. | Transforming measurement data for classification learning |
| AU2007254206A1 (en) * | 2006-05-16 | 2007-11-29 | Source Mdx | Assessment of effect of an agent on a human biological condition using rodent gene expression panels |
| WO2008016111A1 (fr) * | 2006-08-04 | 2008-02-07 | Ajinomoto Co., Inc. | Procédé permettant d'évaluer un cancer du poumon, dispositif d'évaluation d'un cancer du poumon, procédé d'évaluation d'un cancer du poumon, système d'évaluation d'un cancer du poumon, programme d'évaluation d' |
| WO2008021431A2 (en) | 2006-08-14 | 2008-02-21 | Xdx, Inc. | Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders |
| US8148067B2 (en) | 2006-11-09 | 2012-04-03 | Xdx, Inc. | Methods for diagnosing and monitoring the status of systemic lupus erythematosus |
| US20090104605A1 (en) * | 2006-12-14 | 2009-04-23 | Gary Siuzdak | Diagnosis of sepsis |
| JP5746810B2 (ja) * | 2006-12-21 | 2015-07-08 | 味の素株式会社 | 乳癌の評価方法、ならびに乳癌評価装置、乳癌評価方法、乳癌評価システム、乳癌評価プログラムおよび記録媒体 |
| WO2008075664A1 (ja) * | 2006-12-21 | 2008-06-26 | Ajinomoto Co., Inc. | 癌の評価方法、ならびに癌評価装置、癌評価方法、癌評価システム、癌評価プログラムおよび記録媒体 |
| WO2008075663A1 (ja) | 2006-12-21 | 2008-06-26 | Ajinomoto Co., Inc. | 大腸癌の評価方法、ならびに大腸癌評価装置、大腸癌評価方法、大腸癌評価システム、大腸癌評価プログラムおよび記録媒体 |
| US20090117562A1 (en) | 2007-04-09 | 2009-05-07 | Valerie Wailin Hu | Method and kit for diagnosing Autism using gene expression profiling |
| US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
| CA3006428A1 (en) | 2007-06-08 | 2008-12-18 | Genentech, Inc. | Gene expression markers of tumor resistance to her2 inhibitor treatment |
| WO2008154532A1 (en) * | 2007-06-11 | 2008-12-18 | California Pacific Medical Center | Method and kit for dynamic gene expression monitoring |
| US8068994B2 (en) * | 2007-07-27 | 2011-11-29 | Wayne State University | Method for analyzing biological networks |
| EP2209919A4 (en) | 2007-11-14 | 2011-04-13 | Hitachi Chemical Co Ltd | ENHANCED EXPRESSION OF FC RECEPTOR TUMOR NECROSIS NECROSIS FACTOR SUPERFAMILY IN THE PERIFERIC BLOOD LEUKOCYTES |
| US10365279B2 (en) | 2008-01-25 | 2019-07-30 | Berg Llc | Assay system for the assessment of oncogenicity, tumor progression, and treatment efficacy |
| KR101272207B1 (ko) * | 2008-02-06 | 2013-06-07 | 아지노모토 가부시키가이샤 | 위암의 평가 방법, 및 위암 평가 장치, 위암 평가 방법, 위암 평가 시스템, 위암 평가 프로그램 및 기록 매체 |
| WO2009123737A2 (en) | 2008-04-03 | 2009-10-08 | Becton, Dickinson And Company | Advanced detection of sepsis |
| US7776522B2 (en) * | 2008-04-24 | 2010-08-17 | Becton, Dickinson And Company | Methods for diagnosing oncogenic human papillomavirus (HPV) |
| EP2626437A3 (en) | 2008-05-14 | 2013-12-11 | Dermtech International | Diagnosis of melanoma and solar lentigo by nucleic acid analysis |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
| JP5754136B2 (ja) * | 2008-06-20 | 2015-07-29 | 味の素株式会社 | 女性生殖器癌の評価方法、女性生殖器癌評価装置、女性生殖器癌評価方法、女性生殖器癌評価プログラム、記録媒体、女性生殖器癌評価システム、および情報通信端末装置 |
| CN102066946B (zh) | 2008-06-20 | 2016-08-31 | 味之素株式会社 | 前列腺疾病的评价方法 |
| US20100086501A1 (en) * | 2008-08-28 | 2010-04-08 | Dermtech International | Determining Age Ranges of Skin Samples |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US8691510B2 (en) | 2008-11-07 | 2014-04-08 | Sequenta, Inc. | Sequence analysis of complex amplicons |
| GB2467704B (en) * | 2008-11-07 | 2011-08-24 | Mlc Dx Inc | A method for determining a profile of recombined DNA sequences in T-cells and/or B-cells |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| WO2010062960A2 (en) | 2008-11-26 | 2010-06-03 | Cedars-Sinai Medical Center | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE |
| US9580752B2 (en) | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
| PL2387627T3 (pl) | 2009-01-15 | 2016-10-31 | Profilowanie odporności adaptacyjnej i wytwarzanie przeciwciał monoklonalnych | |
| US10179936B2 (en) * | 2009-05-01 | 2019-01-15 | Genomic Health, Inc. | Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy |
| KR20120044941A (ko) | 2009-06-25 | 2012-05-08 | 프레드 헛친슨 켄서 리서치 센터 | 적응 면역의 측정방법 |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| CA2791905A1 (en) | 2010-03-01 | 2011-09-09 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Biomarkers for theranostics |
| CA2795776A1 (en) | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers for disease |
| WO2011156763A1 (en) | 2010-06-11 | 2011-12-15 | Hitachi Chemical Co., Ltd. | Methods for characterizing kidney function |
| WO2011156734A2 (en) * | 2010-06-11 | 2011-12-15 | Hitachi Chemical Co., Ltd. | Method of characterizing vascular diseases |
| JP2013532482A (ja) | 2010-07-27 | 2013-08-19 | ジェノミック ヘルス, インコーポレイテッド | 遺伝子発現を用いた前立腺癌の予後を定量化する方法 |
| WO2012021714A2 (en) * | 2010-08-12 | 2012-02-16 | William Marsh Rice University | Biomarker signatures for wellness testing |
| SG190867A1 (en) | 2010-11-23 | 2013-07-31 | Krisani Biosciences P Ltd | Method and system for prognosis and treatment of diseases using portfolio of genes |
| WO2012109435A1 (en) * | 2011-02-12 | 2012-08-16 | Siemens Healthcare Diagnostics Inc | Environment and method for analysis of genetic sequence data |
| JP5823031B2 (ja) | 2011-06-10 | 2015-11-25 | 日立化成株式会社 | 小胞捕捉デバイスおよびそれを用いるための方法 |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| CA2853088C (en) | 2011-10-21 | 2018-03-13 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| US11130136B2 (en) | 2011-11-14 | 2021-09-28 | Aushon Biosystems, Inc. | Systems and methods to enhance consistency of assay performance |
| ES2867924T3 (es) | 2011-12-09 | 2021-10-21 | Adaptive Biotechnologies Corp | Diagnóstico de tumores malignos linfoides y detección de enfermedad residual mínima |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| EP2809812A4 (en) | 2012-01-31 | 2016-01-27 | Genomic Health Inc | GENE EXPRESSION PROFILE ALGORITHM AND PROSTATE CANCER PROGNOSTIC DETERMINATION TEST |
| ES2662128T3 (es) | 2012-03-05 | 2018-04-05 | Adaptive Biotechnologies Corporation | Determinación de cadenas de receptor inmunitario emparejadas a partir de la frecuencia de subunidades coincidentes |
| JP5756247B1 (ja) | 2012-05-08 | 2015-07-29 | アダプティブ バイオテクノロジーズ コーポレイション | マルチプレックスpcr反応における増幅バイアスを測定し校正する組成物及び方法 |
| CN107449921A (zh) | 2012-05-22 | 2017-12-08 | 博格有限责任公司 | 用于鉴别药物诱导毒性标志物的基于细胞的探询式分析 |
| FR2993282B1 (fr) * | 2012-07-13 | 2017-11-10 | Expanscience Lab | Procede d'identification de marqueurs moleculaires de la peau d'enfant |
| EP2895861A4 (en) | 2012-09-12 | 2016-06-22 | Berg Llc | USE OF MARKERS FOR THE IDENTIFICATION OF CARDIOTOXIC AGENTS |
| EP4044188A1 (en) * | 2012-09-14 | 2022-08-17 | Life Technologies Corporation | Methods and systems for a digital pcr experiment designer |
| ES2660027T3 (es) | 2012-10-01 | 2018-03-20 | Adaptive Biotechnologies Corporation | Evaluación de la inmunocompetencia por la diversidad de los receptores de inmunidad adaptativa y caracterización de la clonalidad |
| WO2015160439A2 (en) | 2014-04-17 | 2015-10-22 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| US10633449B2 (en) | 2013-03-27 | 2020-04-28 | Cedars-Sinai Medical Center | Treatment and reversal of fibrosis and inflammation by inhibition of the TL1A-DR3 signaling pathway |
| JP6297676B2 (ja) | 2013-05-06 | 2018-03-20 | 日立化成株式会社 | 標的分子を捕捉するためのデバイス及び方法 |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| EP3022295A4 (en) | 2013-07-19 | 2017-03-01 | Cedars-Sinai Medical Center | Signature of tl1a (tnfsf15) signaling pathway |
| EP3084664B8 (en) * | 2013-12-16 | 2020-06-17 | Philip Morris Products S.a.s. | Systems and methods for predicting a smoking status of an individual |
| CN105917008B (zh) * | 2014-01-16 | 2020-11-27 | 启迪公司 | 用于前列腺癌复发的预后的基因表达面板 |
| EP3114240B1 (en) | 2014-03-05 | 2019-07-24 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| AU2015289434A1 (en) * | 2014-07-18 | 2017-02-02 | Genova Diagnostics, Inc. | Use of an evidence-based, translational algorithm to, inter alia, assess biomarkers |
| AU2015339191A1 (en) | 2014-10-29 | 2017-05-18 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10266895B2 (en) | 2014-11-05 | 2019-04-23 | Hitachi Chemical Company Ltd. | Exosomes and microvesicles in intestinal luminal fluids and stool and use of same for the assessment of inflammatory bowel disease |
| EP3218521B1 (en) | 2014-11-12 | 2019-12-25 | Hitachi Chemical Co., Ltd. | Method for diagnosing organ injury |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| AU2015353581A1 (en) | 2014-11-25 | 2017-06-15 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| WO2016138122A1 (en) | 2015-02-24 | 2016-09-01 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
| EP3277294B1 (en) | 2015-04-01 | 2024-05-15 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
| CN108271422A (zh) | 2015-06-25 | 2018-07-10 | 株式会社国际电气通信基础技术研究所 | 基于器官间串扰系统的预测装置及预测程序 |
| US10902936B2 (en) * | 2015-07-13 | 2021-01-26 | Koninklijke Philips N.V. | Tracking infections in hospital environments |
| US11028443B2 (en) | 2015-08-31 | 2021-06-08 | Showa Denko Materials Co., Ltd. | Molecular methods for assessing urothelial disease |
| CN105279397B (zh) * | 2015-10-26 | 2017-12-19 | 华东交通大学 | 一种识别蛋白质相互作用网络中关键蛋白质的方法 |
| WO2017161342A1 (en) | 2016-03-17 | 2017-09-21 | Cedars-Sinai Medical Center | Methods of diagnosing inflammatory bowel disease through rnaset2 |
| WO2017170610A1 (ja) | 2016-03-29 | 2017-10-05 | 株式会社国際電気通信基礎技術研究所 | 腎機能低下、慢性腎疾患及び腎不全からなる群から選択される少なくとも一種の疾患を予防、又は治療するための有効成分の候補物質のスクリーニング方法 |
| JP6332780B2 (ja) | 2016-03-29 | 2018-05-30 | 株式会社国際電気通信基礎技術研究所 | 医薬組成物又は食品組成物、及び有効成分の体内での効果の評価方法 |
| US10607720B2 (en) | 2016-05-11 | 2020-03-31 | International Business Machines Corporation | Associating gene expression data with a disease name |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| CN106709267A (zh) * | 2017-01-25 | 2017-05-24 | 武汉贝纳科技服务有限公司 | 数据获取方法及装置 |
| CN107058521B (zh) * | 2017-03-17 | 2019-12-27 | 中国科学院北京基因组研究所 | 一种检测人体免疫状态的检测系统 |
| US12152274B2 (en) | 2017-09-29 | 2024-11-26 | Pharmabio Corporation | Quality management method for regeneration medical product or the like by using standardized expression amount |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| EP3752645A4 (en) | 2018-02-14 | 2022-04-13 | Dermtech, Inc. | Novel gene classifiers and uses thereof in non-melanoma skin cancers |
| WO2019165145A1 (en) * | 2018-02-21 | 2019-08-29 | Iuve, Inc. | Method for measuring systemic chronic inflammaging |
| AU2019235771B2 (en) * | 2018-03-13 | 2025-03-13 | Creatv Microtech, Inc. | Methods for monitoring treatment response and disease progression in subjects using circulating cells |
| WO2019193241A1 (en) * | 2018-04-03 | 2019-10-10 | Nokia Technologies Oy | Use of band combination index for definition of carrier aggregation configurations |
| JP2022524641A (ja) | 2019-03-26 | 2022-05-09 | ダームテック,インク. | 皮膚癌における新規な遺伝子分類子とその使用 |
| KR20210124438A (ko) | 2019-03-26 | 2021-10-14 | 제이에프이 스틸 가부시키가이샤 | 프로세스 상태 감시 장치 및 프로세스 상태 감시 방법 |
| US20230003719A1 (en) * | 2019-12-13 | 2023-01-05 | Janssen Biotech, Inc. | Materials and methods for inflammatory molecular markers |
| WO2023191555A1 (ko) * | 2022-03-30 | 2023-10-05 | 국립암센터 | 만성 간질환 위험도 예측, 진단 또는 예후 예측용 마커로서 ifi16 돌연변이 유전자 및 이의 용도 |
| CN118298911B (zh) * | 2024-04-12 | 2024-11-22 | 中山大学孙逸仙纪念医院 | 一种多部位慢性疼痛潜在治疗靶点确定系统 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5800992A (en) * | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5580722A (en) * | 1989-07-18 | 1996-12-03 | Oncogene Science, Inc. | Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease |
| US5569601A (en) * | 1990-12-07 | 1996-10-29 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | Human dopamine receptor and its uses |
| US6114114A (en) | 1992-07-17 | 2000-09-05 | Incyte Pharmaceuticals, Inc. | Comparative gene transcript analysis |
| ATE160178T1 (de) * | 1993-01-21 | 1997-11-15 | Harvard College | Verfahren und diagnostische kits unter verwendung von säuger-stresspromotoren zur bestimmung der toxizität einer verbindung |
| US5643765A (en) | 1993-04-06 | 1997-07-01 | University Of Rochester | Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction |
| DK0695361T4 (da) * | 1993-04-21 | 2010-03-22 | Univ Edinburgh | Ekspression af heterologe gener ifølge en målekspressionsprofil |
| US6309823B1 (en) * | 1993-10-26 | 2001-10-30 | Affymetrix, Inc. | Arrays of nucleic acid probes for analyzing biotransformation genes and methods of using the same |
| US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
| US5506145A (en) * | 1994-12-02 | 1996-04-09 | Bull; Brian S. | Determination of an individual's inflammation index from whole blood fibrinogen and hematocrit or hemoglobin measurements |
| US5693647A (en) * | 1994-12-22 | 1997-12-02 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| US5968770A (en) * | 1995-02-10 | 1999-10-19 | Millennium Pharmaceuticals, Inc. | Compositions and methods for the treatment and diagnosis of cardiovascular disease using rchd523 as a target |
| US6022683A (en) * | 1996-12-16 | 2000-02-08 | Nova Molecular Inc. | Methods for assessing the prognosis of a patient with a neurodegenerative disease |
| US5866330A (en) * | 1995-09-12 | 1999-02-02 | The Johns Hopkins University School Of Medicine | Method for serial analysis of gene expression |
| US5922184A (en) | 1997-07-21 | 1999-07-13 | Bio-Rad Laboratories, Inc. | Computer-directed detection of paraproteins |
| FR2775984B1 (fr) | 1998-03-11 | 2006-09-15 | Bioscreen Therapeutics Sa | Criblage differentiel qualitatif |
| WO1997041261A1 (en) | 1996-05-02 | 1997-11-06 | Immunological Associates Of Denver | Quantitation of rna transcripts using genomic dna as the internal amplification competitor |
| US5955269A (en) * | 1996-06-20 | 1999-09-21 | Rutgers, The State University Of New Jersey | Methods of screening foods for nutraceuticals |
| US6146828A (en) * | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
| WO1998024935A1 (en) | 1996-12-06 | 1998-06-11 | Urocor, Inc. | Diagnosis of disease state using mrna profiles |
| JPH10261029A (ja) | 1996-12-16 | 1998-09-29 | Nissho Corp | アルツハイマー病生涯罹病性の予測システム |
| US5968784A (en) | 1997-01-15 | 1999-10-19 | Chugai Pharmaceutical Co., Ltd. | Method for analyzing quantitative expression of genes |
| US6165709A (en) * | 1997-02-28 | 2000-12-26 | Fred Hutchinson Cancer Research Center | Methods for drug target screening |
| US5994076A (en) * | 1997-05-21 | 1999-11-30 | Clontech Laboratories, Inc. | Methods of assaying differential expression |
| AU9217198A (en) | 1997-09-03 | 1999-03-22 | Oncormed | Method for predicting prognosis and treatment response for genetically based abnormalities |
| JP2001521753A (ja) | 1997-10-31 | 2001-11-13 | アフィメトリックス インコーポレイテッド | 成人臓器及び胎児臓器中の発現プロフィール |
| JP3784162B2 (ja) | 1998-01-14 | 2006-06-07 | 株式会社日立製作所 | Dna断片分析法 |
| ES2272057T3 (es) | 1998-02-25 | 2007-04-16 | The United States Government As Represented By The Department Of Health And Human Services | Metodo y aparato para realizar una disposicion para la determinacion rapida de perfiles moleculares. |
| EP1071824A2 (en) | 1998-04-23 | 2001-01-31 | Genentech, Inc. | Quantitative analysis of gene expression |
| WO1999057130A1 (en) | 1998-05-05 | 1999-11-11 | Gene Logic, Inc. | A process to study changes in gene expression in t lymphocytes |
| US6232065B1 (en) * | 1998-05-06 | 2001-05-15 | Case Western Reserve University | Analysis of gene family expression |
| US6324479B1 (en) * | 1998-05-08 | 2001-11-27 | Rosetta Impharmatics, Inc. | Methods of determining protein activity levels using gene expression profiles |
| IL139567A0 (en) | 1998-05-12 | 2002-02-10 | Rosetta Inpharmatics Inc | Quantitative methods, systems and apparatuses for gene expression analysis |
| US6218122B1 (en) * | 1998-06-19 | 2001-04-17 | Rosetta Inpharmatics, Inc. | Methods of monitoring disease states and therapies using gene expression profiles |
| US6132969A (en) * | 1998-06-19 | 2000-10-17 | Rosetta Inpharmatics, Inc. | Methods for testing biological network models |
| AU755334C (en) | 1998-08-25 | 2004-02-26 | University Of Washington | Rapid quantitative analysis of proteins or protein function in complex mixtures |
| US6185561B1 (en) * | 1998-09-17 | 2001-02-06 | Affymetrix, Inc. | Method and apparatus for providing and expression data mining database |
| US6245517B1 (en) * | 1998-09-29 | 2001-06-12 | The United States Of America As Represented By The Department Of Health And Human Services | Ratio-based decisions and the quantitative analysis of cDNA micro-array images |
| US20010055760A1 (en) | 1998-10-13 | 2001-12-27 | Alex Chenchik | Nucleic acid arrays |
| US6203987B1 (en) * | 1998-10-27 | 2001-03-20 | Rosetta Inpharmatics, Inc. | Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns |
| DK1058739T3 (da) | 1998-11-05 | 2006-10-09 | Ortho Mcneil Pharm Inc | Fremgangsmåde til dannelse af genekspressionsprofiler |
| US6222093B1 (en) * | 1998-12-28 | 2001-04-24 | Rosetta Inpharmatics, Inc. | Methods for determining therapeutic index from gene expression profiles |
| WO2000058728A1 (fr) * | 1999-03-26 | 2000-10-05 | Uno, Akitane | Moyen d'examen precoce de tumeur maligne |
| WO2000066259A1 (en) * | 1999-05-05 | 2000-11-09 | Ut-Battelle, Llc | Method and apparatus for combinatorial chemistry |
| EP1630709B1 (en) | 1999-05-25 | 2009-09-16 | Aventis Pharmaceuticals Inc. | Mathematical analysis for the estimation of changes in the level of gene expression |
| AU784233B2 (en) * | 1999-06-28 | 2006-02-23 | Life Technologies Corporation | Systems and methods for characterizing a biological condition or agent using calibrated gene expression profiles |
| AU6533700A (en) | 1999-08-09 | 2001-03-05 | Affymetrix, Inc. | Methods of gene expression monitoring |
| WO2001012851A2 (en) | 1999-08-12 | 2001-02-22 | Wisconsin Alumni Research Foundation | Identification of genetic markers of biological age and metabolism |
| WO2001020998A1 (en) | 1999-09-24 | 2001-03-29 | Linden Technologies, Inc. | Drug discovery using gene expression profiling |
| US6505125B1 (en) | 1999-09-28 | 2003-01-07 | Affymetrix, Inc. | Methods and computer software products for multiple probe gene expression analysis |
| WO2001027321A2 (en) | 1999-10-13 | 2001-04-19 | Plant Research International B.V. | Method for detecting differences in gene expression of wild type plants and genetically modified plants |
| US6607885B1 (en) | 1999-10-15 | 2003-08-19 | E. I. Du Pont De Nemours And Company | Method for high-density microarray medicated gene expression profiling |
| EP1287162A2 (en) | 1999-10-21 | 2003-03-05 | Case Western Reserve University | Gene expression profiling of inflammatory bowel disease |
| AU1349801A (en) | 1999-10-26 | 2001-05-08 | Digital Gene Technologies, Inc. | Regulation of gene expression by neuroleptic agents |
| AU1466001A (en) | 1999-11-05 | 2001-05-14 | Phase-1 Molecular Toxicology | Methods of determining individual hypersensitivity to an agent |
| US6248535B1 (en) | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| WO2001075159A2 (en) * | 2000-03-31 | 2001-10-11 | Sir Mortimer B. Davis Jewish General Hospital | Microchip arrays of regulatory genes |
| US7384736B2 (en) * | 2001-09-06 | 2008-06-10 | Decode Genetics Ehf. | Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease |
| JP5236856B2 (ja) | 2001-11-09 | 2013-07-17 | ライフ テクノロジーズ コーポレーション | 遺伝子発現プロファイルを用いる病気の同定、観測及び治療及び生物学的状態の同定 |
-
2002
- 2002-11-08 JP JP2003542649A patent/JP5236856B2/ja not_active Expired - Lifetime
- 2002-11-08 CN CNA02826908XA patent/CN1612936A/zh active Pending
- 2002-11-08 CA CA002466502A patent/CA2466502A1/en not_active Abandoned
- 2002-11-08 US US10/291,856 patent/US6964850B2/en not_active Expired - Lifetime
- 2002-11-08 EP EP02792239.2A patent/EP1451340B1/en not_active Expired - Lifetime
- 2002-11-08 KR KR10-2004-7007103A patent/KR20040064275A/ko not_active Ceased
- 2002-11-08 CN CN2011102265910A patent/CN102402650A/zh active Pending
- 2002-11-08 WO PCT/US2002/036084 patent/WO2003040404A1/en not_active Ceased
-
2005
- 2005-06-22 US US11/158,504 patent/US20050287576A1/en not_active Abandoned
-
2009
- 2009-10-30 US US12/609,578 patent/US8055452B2/en not_active Expired - Fee Related
-
2010
- 2010-11-15 JP JP2010254661A patent/JP2011067214A/ja not_active Withdrawn
-
2011
- 2011-09-21 US US13/239,070 patent/US8718946B2/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017086675A1 (ko) * | 2015-11-19 | 2017-05-26 | 연세대학교 산학협력단 | 대사 이상 질환 진단 장치 및 그 방법 |
| KR20200038660A (ko) * | 2018-10-04 | 2020-04-14 | 사회복지법인 삼성생명공익재단 | 바이오마커의 선별 방법 및 이를 이용한 암의 진단을 위한 정보제공방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| US8055452B2 (en) | 2011-11-08 |
| JP2005508505A (ja) | 2005-03-31 |
| US8718946B2 (en) | 2014-05-06 |
| CA2466502A1 (en) | 2003-05-15 |
| EP1451340B1 (en) | 2014-01-08 |
| JP2011067214A (ja) | 2011-04-07 |
| US20120077199A1 (en) | 2012-03-29 |
| EP1451340A1 (en) | 2004-09-01 |
| EP1451340A4 (en) | 2007-04-11 |
| CN102402650A (zh) | 2012-04-04 |
| US20030219771A1 (en) | 2003-11-27 |
| US20050287576A1 (en) | 2005-12-29 |
| CN1612936A (zh) | 2005-05-04 |
| JP5236856B2 (ja) | 2013-07-17 |
| US20100086935A1 (en) | 2010-04-08 |
| US6964850B2 (en) | 2005-11-15 |
| WO2003040404A1 (en) | 2003-05-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6960439B2 (en) | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles | |
| US6964850B2 (en) | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles | |
| US20180060481A1 (en) | Identification, monitoring and treatment of infectious disease and characterization of inflammatory conditions related to infectious disease using gene expression profiles | |
| US7935482B2 (en) | Gene expression profiling for identification monitoring and treatment of rheumatoid arthritis | |
| Grigoriadis et al. | Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data | |
| US20030229455A1 (en) | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles | |
| Reka et al. | Epithelial–mesenchymal transition-associated secretory phenotype predicts survival in lung cancer patients | |
| JP2005508505A5 (enExample) | ||
| Raeber et al. | Interleukin-2 immunotherapy reveals human regulatory T cell subsets with distinct functional and tissue-homing characteristics | |
| JP2022513038A (ja) | チューブリン結合薬を使用する癌の治療方法 | |
| Xie et al. | Comparisons of gene expression in normal, lesional, and non‐lesional psoriatic skin using DNA microarray techniques | |
| AU2003303238B2 (en) | Identification, monitoring and treatment of infectious disease and characterization of inflammatory conditions related to infectious disease using gene expression profiles | |
| Tao et al. | Differential gene expression profiles of whole lesions from patients with oral lichen planus | |
| Mozooni et al. | The Relationship Between Serum and Tissue Levels of IL-13 and TYK2 in Colorectal Cancer Patients | |
| US20110092390A1 (en) | Assessment of effect of an agent on a human biological condition using rodent gene expression panels | |
| Ranti et al. | Elevated HLA-E and NKG2A as a consequence of chronic immune activation defines resistance to M. bovis BCG immunotherapy in Non-Muscle-Invasive Bladder Cancer | |
| Quan et al. | Bioinformatics Analysis of C3 and CXCR4 act as Potential Prognostic Biomarkers in Clear Cell Renal Cell Carcinoma (ccRCC) | |
| Hinchcliff et al. | Molecular stratification by gene expression as a paradigm for precision medicine in systemic sclerosis | |
| Sweeney | A Systems Biology Approach to Link Nuclear Factor Kappa B Activation with Lethal Prostate Cancer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20040510 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20071108 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20090930 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20100531 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20090930 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |