JP2005508159A5 - - Google Patents
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- Publication number
- JP2005508159A5 JP2005508159A5 JP2003527091A JP2003527091A JP2005508159A5 JP 2005508159 A5 JP2005508159 A5 JP 2005508159A5 JP 2003527091 A JP2003527091 A JP 2003527091A JP 2003527091 A JP2003527091 A JP 2003527091A JP 2005508159 A5 JP2005508159 A5 JP 2005508159A5
- Authority
- JP
- Japan
- Prior art keywords
- alphavirus
- structural protein
- recombinant dna
- cells
- population
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000710929 Alphavirus Species 0.000 claims description 51
- 101710172711 Structural protein Proteins 0.000 claims description 36
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 18
- 108020004511 Recombinant DNA Proteins 0.000 claims description 18
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims description 14
- 108091026890 Coding region Proteins 0.000 claims description 14
- 101710132906 Structural polyprotein Proteins 0.000 claims description 8
- 108091027544 Subgenomic mRNA Proteins 0.000 claims description 7
- 230000010076 replication Effects 0.000 claims description 6
- 230000035897 transcription Effects 0.000 claims description 6
- 238000013518 transcription Methods 0.000 claims description 6
- 108020004414 DNA Proteins 0.000 claims description 3
- 238000000034 method Methods 0.000 claims 18
- 102000053602 DNA Human genes 0.000 claims 15
- 210000004027 cell Anatomy 0.000 claims 15
- 108010087302 Viral Structural Proteins Proteins 0.000 claims 10
- 208000015181 infectious disease Diseases 0.000 claims 8
- 230000002458 infectious effect Effects 0.000 claims 8
- 239000002245 particle Substances 0.000 claims 8
- 206010066919 Epidemic polyarthritis Diseases 0.000 claims 5
- 241000710942 Ross River virus Species 0.000 claims 5
- 230000002950 deficient Effects 0.000 claims 5
- 230000010474 transient expression Effects 0.000 claims 5
- 210000002443 helper t lymphocyte Anatomy 0.000 claims 4
- 230000035772 mutation Effects 0.000 claims 4
- 230000002238 attenuated effect Effects 0.000 claims 3
- 238000004520 electroporation Methods 0.000 claims 3
- 238000004806 packaging method and process Methods 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 230000006798 recombination Effects 0.000 claims 1
- 238000005215 recombination Methods 0.000 claims 1
- 230000001052 transient effect Effects 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
- 230000003362 replicative effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31772201P | 2001-09-06 | 2001-09-06 | |
| US60/317,722 | 2001-09-06 | ||
| PCT/US2002/028610 WO2003023026A1 (en) | 2001-09-06 | 2002-09-06 | Alphavirus replicon vector systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005508159A JP2005508159A (ja) | 2005-03-31 |
| JP2005508159A5 true JP2005508159A5 (enExample) | 2011-01-20 |
| JP4790984B2 JP4790984B2 (ja) | 2011-10-12 |
Family
ID=23234980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003527091A Expired - Lifetime JP4790984B2 (ja) | 2001-09-06 | 2002-09-06 | アルファウイルスレプリコンベクター系 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7045335B2 (enExample) |
| EP (1) | EP1432791B2 (enExample) |
| JP (1) | JP4790984B2 (enExample) |
| AT (1) | ATE437222T1 (enExample) |
| AU (1) | AU2002327614B2 (enExample) |
| CA (1) | CA2460269C (enExample) |
| DE (1) | DE60233061D1 (enExample) |
| ES (1) | ES2330202T5 (enExample) |
| WO (1) | WO2003023026A1 (enExample) |
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-
2002
- 2002-09-06 US US10/237,302 patent/US7045335B2/en not_active Expired - Lifetime
- 2002-09-06 AU AU2002327614A patent/AU2002327614B2/en not_active Expired
- 2002-09-06 CA CA2460269A patent/CA2460269C/en not_active Expired - Lifetime
- 2002-09-06 ES ES02763613.3T patent/ES2330202T5/es not_active Expired - Lifetime
- 2002-09-06 AT AT02763613T patent/ATE437222T1/de not_active IP Right Cessation
- 2002-09-06 JP JP2003527091A patent/JP4790984B2/ja not_active Expired - Lifetime
- 2002-09-06 DE DE60233061T patent/DE60233061D1/de not_active Expired - Lifetime
- 2002-09-06 WO PCT/US2002/028610 patent/WO2003023026A1/en not_active Ceased
- 2002-09-06 EP EP02763613.3A patent/EP1432791B2/en not_active Expired - Lifetime
-
2006
- 2006-03-16 US US11/376,901 patent/US7425337B2/en not_active Expired - Lifetime
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