JP2005506367A5 - - Google Patents

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Publication number
JP2005506367A5
JP2005506367A5 JP2003537620A JP2003537620A JP2005506367A5 JP 2005506367 A5 JP2005506367 A5 JP 2005506367A5 JP 2003537620 A JP2003537620 A JP 2003537620A JP 2003537620 A JP2003537620 A JP 2003537620A JP 2005506367 A5 JP2005506367 A5 JP 2005506367A5
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JP
Japan
Prior art keywords
active substance
pain
weight
release
formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003537620A
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English (en)
Japanese (ja)
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JP2005506367A (ja
JP4758064B2 (ja
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Priority claimed from DE10152469A external-priority patent/DE10152469A1/de
Priority claimed from DE2002148309 external-priority patent/DE10248309A1/de
Application filed filed Critical
Priority claimed from PCT/EP2002/011809 external-priority patent/WO2003035053A1/de
Publication of JP2005506367A publication Critical patent/JP2005506367A/ja
Publication of JP2005506367A5 publication Critical patent/JP2005506367A5/ja
Application granted granted Critical
Publication of JP4758064B2 publication Critical patent/JP4758064B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2003537620A 2001-10-24 2002-10-22 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬 Expired - Lifetime JP4758064B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10152469A DE10152469A1 (de) 2001-10-24 2001-10-24 3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)phenol enthaltendes Arzneimittel mit verzögerter Wirkstofffreisetzung
DE10152469.2 2001-10-24
DE2002148309 DE10248309A1 (de) 2002-10-16 2002-10-16 3-(3- Dimethylamino-1-ethyl-2-methyl-propyl) phenol enthaltendes Arzeimittel mit verzögerter Wirkstofffreisetzung
DE10248309.4 2002-10-16
PCT/EP2002/011809 WO2003035053A1 (de) 2001-10-24 2002-10-22 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol enthaltendes arzneimittel mit verzögerter wirkstofffreisetzung

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010176084A Division JP2010280697A (ja) 2001-10-24 2010-08-05 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬

Publications (3)

Publication Number Publication Date
JP2005506367A JP2005506367A (ja) 2005-03-03
JP2005506367A5 true JP2005506367A5 (enExample) 2010-10-07
JP4758064B2 JP4758064B2 (ja) 2011-08-24

Family

ID=26010444

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003537620A Expired - Lifetime JP4758064B2 (ja) 2001-10-24 2002-10-22 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬
JP2010176084A Pending JP2010280697A (ja) 2001-10-24 2010-08-05 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010176084A Pending JP2010280697A (ja) 2001-10-24 2010-08-05 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬

Country Status (28)

Country Link
US (7) US20050058706A1 (enExample)
EP (1) EP1439829B1 (enExample)
JP (2) JP4758064B2 (enExample)
KR (1) KR100958045B1 (enExample)
CN (1) CN100402021C (enExample)
AR (1) AR036943A1 (enExample)
AT (1) ATE303802T1 (enExample)
AU (1) AU2002349001C1 (enExample)
BR (1) BRPI0213653B8 (enExample)
CA (1) CA2464578C (enExample)
CO (1) CO5570662A2 (enExample)
CY (1) CY2012022I2 (enExample)
DE (1) DE50204198D1 (enExample)
DK (1) DK1439829T3 (enExample)
EC (1) ECSP045102A (enExample)
ES (1) ES2248622T3 (enExample)
HU (1) HU230161B1 (enExample)
IL (2) IL161587A0 (enExample)
MX (1) MXPA04003742A (enExample)
MY (1) MY127797A (enExample)
NO (2) NO331896B1 (enExample)
NZ (1) NZ532999A (enExample)
PE (1) PE20030527A1 (enExample)
PL (1) PL216535B1 (enExample)
PT (1) PT1439829E (enExample)
SI (1) SI1439829T1 (enExample)
WO (2) WO2003035053A1 (enExample)
ZA (1) ZA200403928B (enExample)

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DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
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DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE102004020220A1 (de) * 2004-04-22 2005-11-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
US20070048228A1 (en) * 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
PT1612203E (pt) * 2004-06-28 2007-08-20 Gruenenthal Gmbh ''formas cristalinas de cloridrato de (-) - (1r,2r) - 3 -(3-dimetilamino-l-etil - 2 - metilpropil) fenol''
DE102004032103A1 (de) * 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
WO2006002886A1 (de) * 2004-07-01 2006-01-12 Grünenthal GmbH Gegen missbrauch gesicherte, orale darreichungsform enthaltend (1r, 2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
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HRP20110271T1 (hr) * 2006-04-28 2011-05-31 Grnenthal Gmbh Farmaceutska kombinacija koja sadrži 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol i nsaid (nesteroidni antiinflamatorni lijek)
CN101091725A (zh) * 2006-06-23 2007-12-26 天津天士力制药股份有限公司 一种中药颗粒及其制备方法
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
DE102007011485A1 (de) * 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
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DE102007019417A1 (de) * 2007-04-23 2008-11-13 Grünenthal GmbH Tapentadol zur Schmerzbehandlung bei Arthrose
CA2706596A1 (en) * 2007-11-23 2009-05-28 Protect Pharmaceutical Corporation Tapentadol compositions
SI2240431T1 (sl) * 2007-12-07 2017-05-31 Gruenenthal Gmbh Kristalinične modifikacije (1R,2R)-3-(3-dimetilamino-1-etil-2-metil-propil)-fenola
WO2009092601A1 (en) * 2008-01-25 2009-07-30 Grünenthal GmbH Pharmaceutical dosage form
NZ588863A (en) 2008-05-09 2012-08-31 Gruenenthal Chemie Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
MX2011004455A (es) 2008-10-30 2011-05-25 Gruenenthal Gmbh Formas de dosificacion del tapentadol novedosas y potentes.
JP5667183B2 (ja) 2009-07-22 2015-02-12 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 加熱溶融押出成型した制御放出性投与剤型
ES2718688T3 (es) 2009-07-22 2019-07-03 Gruenenthal Gmbh Forma de dosificación resistente a la manipulación para opioides sensibles a la oxidación
CN102821757B (zh) * 2010-02-03 2016-01-20 格吕伦塔尔有限公司 通过挤出机制备粉末状药物组合物
JP5905872B2 (ja) * 2010-04-07 2016-04-20 ルピン・リミテッド タペンタドールの制御放出医薬組成物
EP2566461A2 (de) * 2010-05-05 2013-03-13 Ratiopharm GmbH Festes tapentadol in nicht-kristalliner form
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RS55009B1 (sr) 2010-06-30 2016-11-30 Gruenenthal Gmbh Tapentadol za upotrebu u lečenju sindroma nervoznih creva
ES2860676T3 (es) 2010-07-23 2021-10-05 Gruenenthal Gmbh Sales o cocristales de 3- (3-dimetilamino-1-etil-2-metil-propil) -fenol
US9636303B2 (en) 2010-09-02 2017-05-02 Gruenenthal Gmbh Tamper resistant dosage form comprising an anionic polymer
CN103269688A (zh) 2010-09-02 2013-08-28 格吕伦塔尔有限公司 包含无机盐的抗破碎剂型
HUE037491T2 (hu) 2011-03-04 2018-09-28 Gruenenthal Gmbh Félszilárd vizes, tapentadolt tartalmazó gyógyszerkészítmény
KR101970468B1 (ko) 2011-03-04 2019-04-19 그뤼넨탈 게엠베하 타펜타돌의 비경구 투여
RS60267B1 (sr) 2011-03-04 2020-06-30 Gruenenthal Gmbh Vodena farmaceutska formulacija tapentadola za oralnu primenu
PL2694050T3 (pl) 2011-04-05 2020-03-31 Grünenthal GmbH Tapentadol do stosowania w leczeniu bólu związanego z nerwobólami nerwu trójdzielnego
DK2694049T3 (da) 2011-04-05 2019-01-02 Gruenenthal Gmbh Tapentadol til forebyggelse af kronificering af smerte
HUE049308T2 (hu) 2011-04-29 2020-09-28 Gruenenthal Gmbh Tapentadol alkalmazása depresszió és szorongás megelõzésére és kezelésére
JP6038138B2 (ja) * 2011-07-29 2016-12-07 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 3−[(1s,2s)−3−(ジメチルアミノ)−1−エチル−2−メチルプロピル]フェノールのくも膜下投与または硬膜外投与
EP2736495B1 (en) 2011-07-29 2017-08-23 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
NO2736497T3 (enExample) 2011-07-29 2018-01-20
EP2606879A1 (en) 2011-12-21 2013-06-26 Hexal AG Multiple unit pellet tablet formulation comprising an opioid
MX356421B (es) 2012-02-28 2018-05-29 Gruenenthal Gmbh Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
TR201815502T4 (tr) 2012-04-18 2018-11-21 Gruenenthal Gmbh Kurcalama veya dirençli ve doz boşalımına dirençli farmasötik dozaj formu.
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
MX2015016254A (es) 2013-05-29 2016-04-20 Gruenenthal Gmbh Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal.
US10154966B2 (en) 2013-05-29 2018-12-18 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
EP2808319A1 (en) 2013-05-31 2014-12-03 Arevipharma GmbH 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex
CN105682643B (zh) 2013-07-12 2019-12-13 格吕伦塔尔有限公司 含有乙烯-醋酸乙烯酯聚合物的防篡改剂型
EP2845625A1 (en) 2013-09-04 2015-03-11 Grünenthal GmbH Tapentadol for use in the treatment of fibromyalgia and chronic fatigue syndrome
WO2015071248A1 (en) 2013-11-15 2015-05-21 Synthon B.V. Abuse-proofed extended release pharmaceutical composition comprising tapentadol
JP6480936B2 (ja) 2013-11-26 2019-03-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング クライオミリングによる粉末状医薬組成物の調製
EP2942054A1 (en) * 2014-05-09 2015-11-11 G.L. Pharma GmbH Slow-release pharmaceutical formulation
EP3142646A1 (en) 2014-05-12 2017-03-22 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
JP2017516789A (ja) 2014-05-26 2017-06-22 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エタノール過量放出に対して防護されている多粒子
EP3273953B1 (en) 2015-03-27 2019-01-02 Grünenthal GmbH Stable formulation for parenteral administration of tapentadol
HK1246173A1 (zh) 2015-04-24 2018-09-07 Grünenthal GmbH 具有立即释放和对溶剂萃取的抗性的抗篡改剂型
US10842750B2 (en) 2015-09-10 2020-11-24 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
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WO2018153947A1 (en) 2017-02-23 2018-08-30 Grünenthal GmbH Tapentadol as local anesthetic
US20180369151A1 (en) * 2017-05-29 2018-12-27 Grünenthal GmbH Multiparticulate oral dosage form providing prolonged release of tapentadol
AU2020100441B4 (en) * 2020-03-02 2020-06-18 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
AU2020100442B4 (en) * 2020-03-02 2020-06-18 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
HRP20240081T1 (hr) * 2020-03-02 2024-05-24 Grünenthal GmbH Oblik doziranja koji pruža produljeno oslobađanje soli tapentadol-fosforne kiseline
PE20230105A1 (es) 2020-03-02 2023-01-25 Gruenenthal Chemie Forma de dosificacion que proporciona liberacion prolongada de sal de acido fosforico de tapentadol
EP3875079A1 (en) * 2020-03-02 2021-09-08 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
EP4121013B1 (en) 2020-03-16 2025-01-15 Grünenthal GmbH Scored tablet comprising tapentadol
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