JP2005506354A - 癌治療のためのオリゴアミン化合物およびその誘導体 - Google Patents

癌治療のためのオリゴアミン化合物およびその誘導体 Download PDF

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Publication number
JP2005506354A
JP2005506354A JP2003536196A JP2003536196A JP2005506354A JP 2005506354 A JP2005506354 A JP 2005506354A JP 2003536196 A JP2003536196 A JP 2003536196A JP 2003536196 A JP2003536196 A JP 2003536196A JP 2005506354 A JP2005506354 A JP 2005506354A
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compound
chohch
group
another embodiment
butyl
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JP2005506354A5 (fr
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ベンジャミン フライドマン，
アルドニア エル． バラシナス，
アンドレイ ブイ． ブロックヒン，
ヒラク エス． バス，
ロウレンス ジェイ． マートン，
ベノドハー ケイ． レディー，
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スリル バイオメディカル コーポレイション
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Publication of JP2005506354A publication Critical patent/JP2005506354A/ja
Publication of JP2005506354A5 publication Critical patent/JP2005506354A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/18—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2003536196A 2001-10-16 2002-10-16 癌治療のためのオリゴアミン化合物およびその誘導体 Pending JP2005506354A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32998201P 2001-10-16 2001-10-16
PCT/US2002/032932 WO2003033455A1 (fr) 2001-10-16 2002-10-16 Composes oligoamine et leurs derives pour le traitement des cancers

Publications (2)

Publication Number Publication Date
JP2005506354A true JP2005506354A (ja) 2005-03-03
JP2005506354A5 JP2005506354A5 (fr) 2009-01-15

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Family Applications (1)

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JP2003536196A Pending JP2005506354A (ja) 2001-10-16 2002-10-16 癌治療のためのオリゴアミン化合物およびその誘導体

Country Status (7)

Country Link
US (3) US20030130356A1 (fr)
EP (1) EP1436246A1 (fr)
JP (1) JP2005506354A (fr)
AU (2) AU2002340224B2 (fr)
CA (1) CA2463771A1 (fr)
IL (1) IL161428A0 (fr)
WO (1) WO2003033455A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011503050A (ja) * 2007-11-08 2011-01-27 イッサム リサーチ ディべロップメント カンパニー オブ ザ ヘブライ ユニバーシティー オブ エルサレム，リミテッド スフィンゴリピドの新規合成アナログ

Families Citing this family (17)

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AU4679900A (en) * 1999-04-30 2000-11-17 Slil Biomedical Corporation Conformationally restricted polyamine analogs as disease therapies
JP2002543163A (ja) * 1999-04-30 2002-12-17 スリル バイオメディカル コーポレイション 癌および前立腺疾患のための治療としての結合体
EP1436246A1 (fr) * 2001-10-16 2004-07-14 SLIL Biomedical Corporation Composes oligoamine et leurs derives pour le traitement des cancers
EP1453787A1 (fr) * 2001-12-07 2004-09-08 SLIL Biomedical Corporation Polyamines substituees par un cycloalkyle pour le traitement du cancer, et procedes de synthese de celles-ci
US7026347B2 (en) * 2002-06-26 2006-04-11 Cellgate, Inc. Porphyrin-polyamine conjugates for cancer therapy
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US7075146B2 (en) * 2004-02-24 2006-07-11 Micron Technology, Inc. 4F2 EEPROM NROM memory arrays with vertical devices
WO2006041805A1 (fr) * 2004-10-04 2006-04-20 Cellgate, Inc. Analogues de polyamine comme agents therapeutiques pour maladies oculaires
WO2006086773A2 (fr) * 2005-02-11 2006-08-17 Cellgate, Inc. Analogues de polyamine en tant que modulateurs de la migration cellulaire et de la motilite cellulaire
WO2007106554A2 (fr) * 2006-03-14 2007-09-20 Progen Pharmaceuticals, Inc. Traitement et prevention d'hyperplasie vasculaire utilisant de la polyamine et des composes d'analogues de polyamine
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US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
WO2016033368A1 (fr) 2014-08-27 2016-03-03 Ohio State Innovation Foundation Inhibiteurs améliorés de la peptidyl-calcineurine
US11576946B2 (en) 2018-01-29 2023-02-14 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-NFAT interaction
WO2019165183A1 (fr) 2018-02-22 2019-08-29 Entrada Therapeutics, Inc. Compositions et méthodes de traitement de l'encéphalopathie mitochondriale neurogastro-intestinale

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JP2011503050A (ja) * 2007-11-08 2011-01-27 イッサム リサーチ ディべロップメント カンパニー オブ ザ ヘブライ ユニバーシティー オブ エルサレム，リミテッド スフィンゴリピドの新規合成アナログ

Also Published As

Publication number Publication date
AU2002340224B2 (en) 2008-11-27
AU2009200639A1 (en) 2009-03-12
US7491849B2 (en) 2009-02-17
EP1436246A1 (fr) 2004-07-14
WO2003033455A1 (fr) 2003-04-24
US20090124832A1 (en) 2009-05-14
IL161428A0 (en) 2004-09-27
CA2463771A1 (fr) 2003-04-24
US20050080144A1 (en) 2005-04-14
US20030130356A1 (en) 2003-07-10

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