IL161428A0 - Oligoamine derivatives, methods for the production thereof and pharmaceutical compositions containing the same - Google Patents

Oligoamine derivatives, methods for the production thereof and pharmaceutical compositions containing the same

Info

Publication number
IL161428A0
IL161428A0 IL16142802A IL16142802A IL161428A0 IL 161428 A0 IL161428 A0 IL 161428A0 IL 16142802 A IL16142802 A IL 16142802A IL 16142802 A IL16142802 A IL 16142802A IL 161428 A0 IL161428 A0 IL 161428A0
Authority
IL
Israel
Prior art keywords
production
methods
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL16142802A
Other languages
English (en)
Original Assignee
Slil Biomedical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Slil Biomedical Corp filed Critical Slil Biomedical Corp
Publication of IL161428A0 publication Critical patent/IL161428A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/18—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
IL16142802A 2001-10-16 2002-10-16 Oligoamine derivatives, methods for the production thereof and pharmaceutical compositions containing the same IL161428A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32998201P 2001-10-16 2001-10-16
PCT/US2002/032932 WO2003033455A1 (en) 2001-10-16 2002-10-16 Oligoamine compounds and derivatives thereof for cancer therapy

Publications (1)

Publication Number Publication Date
IL161428A0 true IL161428A0 (en) 2004-09-27

Family

ID=23287844

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16142802A IL161428A0 (en) 2001-10-16 2002-10-16 Oligoamine derivatives, methods for the production thereof and pharmaceutical compositions containing the same

Country Status (7)

Country Link
US (3) US20030130356A1 (xx)
EP (1) EP1436246A1 (xx)
JP (1) JP2005506354A (xx)
AU (2) AU2002340224B2 (xx)
CA (1) CA2463771A1 (xx)
IL (1) IL161428A0 (xx)
WO (1) WO2003033455A1 (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1177197B1 (en) * 1999-04-30 2006-08-09 Cellgate, Inc. Polyamines and their use in therapy
JP2002543163A (ja) * 1999-04-30 2002-12-17 スリル バイオメディカル コーポレイション 癌および前立腺疾患のための治療としての結合体
CA2463771A1 (en) * 2001-10-16 2003-04-24 Slil Biomedical Corporation Oligoamine compounds and derivatives thereof for cancer therapy
EP1453787A1 (en) 2001-12-07 2004-09-08 SLIL Biomedical Corporation Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
AU2003279756A1 (en) * 2002-06-26 2004-01-19 Cellgate, Inc. Porphyrin-polyamine conjugates for cancer therapy
US7095075B2 (en) * 2003-07-01 2006-08-22 Micron Technology, Inc. Apparatus and method for split transistor memory having improved endurance
US7241654B2 (en) * 2003-12-17 2007-07-10 Micron Technology, Inc. Vertical NROM NAND flash memory array
US7075146B2 (en) * 2004-02-24 2006-07-11 Micron Technology, Inc. 4F2 EEPROM NROM memory arrays with vertical devices
CA2583110A1 (en) * 2004-10-04 2006-04-20 Cellgate, Inc. Polyamine analogs as therapeutic agents for ocular diseases
US20090143456A1 (en) * 2005-02-11 2009-06-04 Marton Laurence J Polyamine Analogs as Modulators of Cell Migration and Cell Motility
WO2007106554A2 (en) * 2006-03-14 2007-09-20 Progen Pharmaceuticals, Inc. Treatment and prevention of vascular hyperplasia using polyamine and polyamine analog compounds
IL187247A0 (en) * 2007-11-08 2008-12-29 Hadasit Med Res Service Novel synthetic analogs of sphingolipids
FR2932088B1 (fr) * 2008-06-06 2013-04-05 Lvmh Rech Utilisation d'un extrait de lepechinia caulescens comme agent cosmetique, et composition cosmetique le contenant
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
JP6807831B2 (ja) 2014-05-21 2021-01-06 エントラーダ セラピューティクス，インコーポレイテッド 細胞膜透過性ペプチド、並びにこの作製方法及び使用方法
US10456443B2 (en) 2014-08-27 2019-10-29 Ohio State Innovation Foundation Peptidyl calcineurin inhibitors
US11576946B2 (en) 2018-01-29 2023-02-14 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-NFAT interaction
EP3755351A4 (en) 2018-02-22 2021-11-24 Entrada Therapeutics, Inc. COMPOSITIONS AND TREATMENT METHODS FOR MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2440724A (en) * 1944-10-27 1948-05-04 Commercial Solvents Corp Nu-substituted, 2-butene-1, 4-diamines, and process for preparing
US4013507A (en) * 1973-09-18 1977-03-22 California Institute Of Technology Ionene polymers for selectively inhibiting the vitro growth of malignant cells
US3956502A (en) * 1974-09-04 1976-05-11 Nalco Chemical Company Polyamine alcohols as microbiocides
PL109855B1 (en) 1977-12-12 1980-06-30 Bath for electro-galvanizing and polishing
US4661509A (en) * 1982-09-28 1987-04-28 Gordon Arnold Z Methods for treating leukopenia
US4551550A (en) * 1983-12-06 1985-11-05 Merrell Dow Pharmaceuticals Inc. N-2,3-Butadienyl-1,4-butanediamine derivatives
CA1247598A (en) * 1984-12-27 1988-12-28 Harry J. Andress, Jr. Compounds containing amide linkages from mono-and polycarboxylic acids in the same molecule and lubricants and fuels containing same
CS252771B1 (cs) * 1986-01-20 1987-10-15 Josef Urbanek Reakční produkty vyšších nasycených a/nebo nenasycených karboxylových kyselin s polytopickými aminy
US4889851A (en) * 1986-11-21 1989-12-26 Fujisawa Pharmaceutical Co, Ltd. Benzothiadiazine compounds, and pharmaceutical composition comprising the same
US5091576A (en) * 1986-12-02 1992-02-25 University Of Florida Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
US5677351A (en) * 1986-12-02 1997-10-14 University Of Florida Research Foundation, Inc. Sterically hindered tetraamines and method for their production
US5342945A (en) * 1986-12-02 1994-08-30 University Of Florida Research Foundation, Inc. Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
US6184232B1 (en) * 1986-12-02 2001-02-06 University Of Florida Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment
US5393757A (en) * 1986-12-02 1995-02-28 University Of Florida Polyamines and anti-diarrheal and gastrointestinal anti-spasmodic pharmaceutical compositions and methods of treatment
USRE38417E1 (en) * 1986-12-02 2004-02-03 University Of Florida Research Foundation, Inc. Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
US5654484A (en) * 1987-10-08 1997-08-05 Merrell Pharmaceuticals Inc. Polyamine derivatives as antineoplastic agents
US4868219A (en) * 1988-04-07 1989-09-19 Thornfeldt Carl R Treatment of skin diseases with aliphatic amines
CA2011367C (en) * 1988-08-30 1997-07-08 Henry Ashjian Reaction products of alkenyl succinimides with ethylenediamine carboxy acids as fuel detergents
US5719193A (en) * 1989-05-23 1998-02-17 Merrell Pharmaceuticals, Inc. Method of potentiating cell-mediated immunity utilizing polyamine derivatives
US5283367A (en) * 1989-08-30 1994-02-01 Ciba-Geigy Corporation Substituted 1,4-diamino-2-butene stabilizers
JP3007391B2 (ja) * 1990-08-13 2000-02-07 花王株式会社 新規第４級アンモニウム化合物
GB9111794D0 (en) * 1991-05-31 1991-07-24 Robins David J Antifungal compounds
BR9206403A (pt) 1991-08-23 1994-12-27 Pfizer Aril-poliaminas sintéticas como antagonistas de neurotransmissores aminoácidos excitadores
US5185369A (en) * 1991-08-23 1993-02-09 Pfizer Inc. Synthetic heteroaryl polyamines as excitatory amino acid neurotransmitter antagonists
US5242684A (en) * 1991-10-25 1993-09-07 Isp Investments Inc. Antimicrobial, low toxicity, non-irritating composition comprising a blend of bis-quaternary ammonium compounds coprecipitated with a copolymer of vinylpyrrolidone and an acrylamido or vinyl quaternary ammonium monomer
US5512597A (en) * 1991-11-08 1996-04-30 Alcon Laboratories, Inc. Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials
US6051611A (en) * 1991-11-08 2000-04-18 Alcon Laboratories, Inc. Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobias
US5530092A (en) * 1992-01-13 1996-06-25 Dsm N.V. Dendritic macromolecule and the preparation thereof
GB9220921D0 (en) 1992-10-05 1992-11-18 Merrell Dow Pharma Polyamine derivatives as anticytomegaloviral agents
DE4306152A1 (de) * 1993-02-27 1994-09-01 Hoechst Ag Positiv arbeitendes strahlungsempfindliches Gemisch und damit hergestelltes Aufzeichnungsmaterial
US5451347A (en) * 1993-06-24 1995-09-19 Lumigen, Inc. Methods and compositions providing enhanced chemiluminescence from chemiluminescent compounds using dicationic surfactants
US5541230A (en) * 1993-11-05 1996-07-30 Us Health Therapeutic polyamines
DK0686143T3 (da) 1993-12-27 1999-05-17 Novartis Ag Umættede aminoforbindelser som middel mod cancer og mod protozoer
DE4403039A1 (de) 1994-01-28 1995-08-03 Schering Ag Oktaazamakrocyclen, deren Metallkomplexe, Verfahren zu deren Herstellung, diese Komplexe enthaltende Mittel sowie deren Verwendung in Diagnostik und Therapie
WO1995020619A1 (en) * 1994-01-28 1995-08-03 Dsm N.V. Dendritic macromolecule and a process for the preparation thereof
JPH07228589A (ja) 1994-02-16 1995-08-29 Fuji Photo Film Co Ltd リン酸エステル誘導体およびそれを含有するハロゲン化銀写真感光材料
JPH07277964A (ja) 1994-04-08 1995-10-24 Nippon Kayaku Co Ltd 抗腫瘍剤
DE59505727D1 (de) * 1994-11-12 1999-05-27 Basf Ag Verfahren zur herstellung von aminen aus verbindungen mit mindestens 3 cyanogruppen
FR2729852A1 (fr) * 1995-01-30 1996-08-02 Oreal Composition reductrice comprenant un acide amine basique et un polymere cationique
EP0752465A1 (en) 1995-06-01 1997-01-08 The Procter & Gamble Company Betaine esters for delivery of alcohols
EP0761680A3 (en) * 1995-09-12 1999-05-06 Ono Pharmaceutical Co., Ltd. Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity
US5869715A (en) * 1995-09-27 1999-02-09 The Reagents Of The University Of California Polyfunctional cationic cytofectins
US5886051A (en) * 1995-11-08 1999-03-23 University Of Florida Research Foundation, Inc. Methods and compositions for the treatment of neurodegeneration
US6126964A (en) * 1996-01-04 2000-10-03 Mirus Corporation Process of making a compound by forming a polymer from a template drug
US5962533A (en) * 1996-02-06 1999-10-05 University Of Florida Research Foundation, Inc. Hydroxy polyamines
JP3939355B2 (ja) * 1996-02-07 2007-07-04 バックマン・ラボラトリーズ・インターナショナル・インコーポレーテッド イオネンポリマーおよびドデシルアミン塩を含有する相乗的殺菌剤組成物ならびにその使用方法
DE19621510A1 (de) * 1996-05-29 1997-12-04 Basf Ag Dendritische stickstoffhaltige organische Verbindungen mit planar-chiralen oder axial-chiralen Endgruppen, ihre Herstellung und Verwendung
US6034129A (en) * 1996-06-24 2000-03-07 Geltex Pharmaceuticals, Inc. Ionic polymers as anti-infective agents
DE19625982A1 (de) * 1996-06-28 1998-01-02 Wella Ag Kosmetisches Mittel zur Haarbehandlung mit Dendrimeren
US5866016A (en) * 1997-07-01 1999-02-02 Buckman Laboratories International, Inc. Methods and compositions for controlling biofouling using combinations of an ionene polymer and a salt of dodecylamine
US5958397A (en) * 1996-07-22 1999-09-28 Schering-Plough Healthcare Products, Inc. Method and composition for protecting against jellyfish stings
US5906996A (en) * 1996-08-21 1999-05-25 Murphy; Michael A. Tetramine treatment of neurological disorders
AU733866B2 (en) * 1996-09-13 2001-05-31 University Of Florida Research Foundation, Inc. Method of inhibiting biosynthesis of EIf5A
EP0889112A1 (en) 1996-10-22 1999-01-07 Tonen Corporation Lubricating oil composition for automatic transmissions
US6235794B1 (en) * 1997-04-03 2001-05-22 University Of Florida Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment
US6307102B1 (en) * 1997-10-15 2001-10-23 Tosoh Corporation Amine catalyst for producing polyurethane and polyisocyanurate
US6046282A (en) * 1998-01-06 2000-04-04 Air Products And Chemicals, Inc. Reactive diluents for polyamidoamine epoxy curatives
WO1999043752A1 (fr) * 1998-02-27 1999-09-02 Dnavec Research Inc. Compositions pour transporter des substances chargees negativement
JP3996274B2 (ja) 1998-07-07 2007-10-24 電気化学工業株式会社 モノビニルアセチレンの製造方法
US6531512B1 (en) * 1998-07-31 2003-03-11 Health Research Inc. Method of treating cancer in patients having a deficiency in p53 tumor suppressor gene
EP1050304A1 (en) * 1998-11-16 2000-11-08 Rohto Pharmaceutical Co., Ltd. Liquid ophthalmic preparations
JP3747355B2 (ja) * 1998-12-21 2006-02-22 独立行政法人理化学研究所 鎖状ポリアミン系化合物及びポリアミン系抗ガン剤
US6649587B1 (en) * 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
JP2002543163A (ja) * 1999-04-30 2002-12-17 スリル バイオメディカル コーポレイション 癌および前立腺疾患のための治療としての結合体
US6673890B1 (en) * 1999-07-16 2004-01-06 Basf Aktiengesellschaft Zwitterionic polyamines and process for their production
GB9920107D0 (en) * 1999-08-26 1999-10-27 Avecia Ltd Fluidising agents
JP2001131449A (ja) 1999-11-01 2001-05-15 Matsushita Electric Ind Co Ltd インクジェット記録用インク
FR2802817B1 (fr) * 1999-12-23 2002-10-11 Centre Nat Rech Scient Nouveaux inhibiteurs de glycosidases et leurs applications pharmacologiques, notamment pour traiter le diabete
DE60128407T2 (de) * 2000-01-10 2008-01-10 Zetetic Research, Inc., Coconut Creek Verwendung einer pharmazeutischen zusammensetzung enthaltend zwei quaternäre ammoniumverbindungen und eine organometal-verbindung zur behandlung von viralen und fungalen infekten und krankheiten
US6444707B1 (en) * 2000-08-22 2002-09-03 West Agro Topically applied hoof treatment composition and concentrate
EP1318801B1 (en) * 2000-09-19 2009-03-11 Dermal Therapy (Barbados) Inc. Topical analgesic compositions containing aliphatic polyamines and methods of using same
US6545181B1 (en) * 2000-10-24 2003-04-08 Pilot Chemical Holdings, Inc. Demulsifying compound and a method of breaking or inhibiting emulsions
AU2002235126A1 (en) * 2000-11-08 2002-05-21 Slil Biomedical Corporation Novel polyamine analog-amino acid conjugates useful as anticancer agents
US7754765B2 (en) * 2000-12-01 2010-07-13 Radical Vision Therapeutics Inc Copper chelators for treating ocular inflammation
DE60132494T2 (de) * 2000-12-01 2008-12-24 Radical Vision Therapeutics Inc. Kupferchelatbildner zur behandlung von augenentzündungen
US6399662B1 (en) * 2000-12-13 2002-06-04 University Of Florida Method and composition for the treatment of diarrhea and gastrointestinal spasms
US6635679B2 (en) * 2001-05-14 2003-10-21 Akzo Nobel N.V. Methods and compositions for inactivating viruses
US6713653B2 (en) * 2001-08-24 2004-03-30 E. I. Du Pont De Nemours And Company Polyamines and polymers made therewith
CA2463771A1 (en) * 2001-10-16 2003-04-24 Slil Biomedical Corporation Oligoamine compounds and derivatives thereof for cancer therapy
US6458795B1 (en) * 2001-11-15 2002-10-01 University Of Florida Method and composition for treatment of irritable bowel disease
JP2005510524A (ja) * 2001-11-16 2005-04-21 アルス・セラピー・デベロツプメント・フアンデーシヨン・インコーポレーテツド ポリアミン経路の調節による神経変性障害の治療
US20050027016A1 (en) * 2002-02-07 2005-02-03 Fahl Kathleen L Polyamine compounds and compositions for use in conjection with cancer therapy
US6881732B2 (en) * 2002-06-13 2005-04-19 Chelator Llc Neuroprotection and cardioprotection afforded by chelators with high affinity and specificity for cations of first transition series elements
US7189865B2 (en) * 2002-07-23 2007-03-13 Attenuon, Llc Thiomolybdate analogues and uses thereof
US20040019043A1 (en) * 2002-07-23 2004-01-29 Dimitri Coucouvanis Thiomolybdate analogues and uses thereof

Also Published As

Publication number Publication date
WO2003033455A1 (en) 2003-04-24
JP2005506354A (ja) 2005-03-03
US20050080144A1 (en) 2005-04-14
AU2002340224B2 (en) 2008-11-27
CA2463771A1 (en) 2003-04-24
AU2009200639A1 (en) 2009-03-12
EP1436246A1 (en) 2004-07-14
US20090124832A1 (en) 2009-05-14
US20030130356A1 (en) 2003-07-10
US7491849B2 (en) 2009-02-17

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