IL161428A0 - Oligoamine derivatives, methods for the production thereof and pharmaceutical compositions containing the same - Google Patents
Oligoamine derivatives, methods for the production thereof and pharmaceutical compositions containing the sameInfo
- Publication number
- IL161428A0 IL161428A0 IL16142802A IL16142802A IL161428A0 IL 161428 A0 IL161428 A0 IL 161428A0 IL 16142802 A IL16142802 A IL 16142802A IL 16142802 A IL16142802 A IL 16142802A IL 161428 A0 IL161428 A0 IL 161428A0
- Authority
- IL
- Israel
- Prior art keywords
- production
- methods
- same
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/18—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32998201P | 2001-10-16 | 2001-10-16 | |
PCT/US2002/032932 WO2003033455A1 (fr) | 2001-10-16 | 2002-10-16 | Composes oligoamine et leurs derives pour le traitement des cancers |
Publications (1)
Publication Number | Publication Date |
---|---|
IL161428A0 true IL161428A0 (en) | 2004-09-27 |
Family
ID=23287844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16142802A IL161428A0 (en) | 2001-10-16 | 2002-10-16 | Oligoamine derivatives, methods for the production thereof and pharmaceutical compositions containing the same |
Country Status (7)
Country | Link |
---|---|
US (3) | US20030130356A1 (fr) |
EP (1) | EP1436246A1 (fr) |
JP (1) | JP2005506354A (fr) |
AU (2) | AU2002340224B2 (fr) |
CA (1) | CA2463771A1 (fr) |
IL (1) | IL161428A0 (fr) |
WO (1) | WO2003033455A1 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4679900A (en) * | 1999-04-30 | 2000-11-17 | Slil Biomedical Corporation | Conformationally restricted polyamine analogs as disease therapies |
JP2002543163A (ja) * | 1999-04-30 | 2002-12-17 | スリル バイオメディカル コーポレイション | 癌および前立腺疾患のための治療としての結合体 |
EP1436246A1 (fr) * | 2001-10-16 | 2004-07-14 | SLIL Biomedical Corporation | Composes oligoamine et leurs derives pour le traitement des cancers |
EP1453787A1 (fr) * | 2001-12-07 | 2004-09-08 | SLIL Biomedical Corporation | Polyamines substituees par un cycloalkyle pour le traitement du cancer, et procedes de synthese de celles-ci |
US7026347B2 (en) * | 2002-06-26 | 2006-04-11 | Cellgate, Inc. | Porphyrin-polyamine conjugates for cancer therapy |
US7095075B2 (en) * | 2003-07-01 | 2006-08-22 | Micron Technology, Inc. | Apparatus and method for split transistor memory having improved endurance |
US7241654B2 (en) * | 2003-12-17 | 2007-07-10 | Micron Technology, Inc. | Vertical NROM NAND flash memory array |
US7075146B2 (en) * | 2004-02-24 | 2006-07-11 | Micron Technology, Inc. | 4F2 EEPROM NROM memory arrays with vertical devices |
WO2006041805A1 (fr) * | 2004-10-04 | 2006-04-20 | Cellgate, Inc. | Analogues de polyamine comme agents therapeutiques pour maladies oculaires |
WO2006086773A2 (fr) * | 2005-02-11 | 2006-08-17 | Cellgate, Inc. | Analogues de polyamine en tant que modulateurs de la migration cellulaire et de la motilite cellulaire |
WO2007106554A2 (fr) * | 2006-03-14 | 2007-09-20 | Progen Pharmaceuticals, Inc. | Traitement et prevention d'hyperplasie vasculaire utilisant de la polyamine et des composes d'analogues de polyamine |
IL187247A0 (en) * | 2007-11-08 | 2008-12-29 | Hadasit Med Res Service | Novel synthetic analogs of sphingolipids |
FR2932088B1 (fr) * | 2008-06-06 | 2013-04-05 | Lvmh Rech | Utilisation d'un extrait de lepechinia caulescens comme agent cosmetique, et composition cosmetique le contenant |
CN113861268A (zh) | 2014-05-21 | 2021-12-31 | 恩特拉达治疗学股份有限公司 | 细胞穿透肽及其制备和使用方法 |
US10815276B2 (en) | 2014-05-21 | 2020-10-27 | Entrada Therapeutics, Inc. | Cell penetrating peptides and methods of making and using thereof |
WO2016033368A1 (fr) | 2014-08-27 | 2016-03-03 | Ohio State Innovation Foundation | Inhibiteurs améliorés de la peptidyl-calcineurine |
US11576946B2 (en) | 2018-01-29 | 2023-02-14 | Ohio State Innovation Foundation | Peptidyl inhibitors of calcineurin-NFAT interaction |
WO2019165183A1 (fr) | 2018-02-22 | 2019-08-29 | Entrada Therapeutics, Inc. | Compositions et méthodes de traitement de l'encéphalopathie mitochondriale neurogastro-intestinale |
Family Cites Families (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2440724A (en) | 1944-10-27 | 1948-05-04 | Commercial Solvents Corp | Nu-substituted, 2-butene-1, 4-diamines, and process for preparing |
US4013507A (en) | 1973-09-18 | 1977-03-22 | California Institute Of Technology | Ionene polymers for selectively inhibiting the vitro growth of malignant cells |
US3956502A (en) | 1974-09-04 | 1976-05-11 | Nalco Chemical Company | Polyamine alcohols as microbiocides |
PL109855B1 (en) | 1977-12-12 | 1980-06-30 | Bath for electro-galvanizing and polishing | |
US4661509A (en) | 1982-09-28 | 1987-04-28 | Gordon Arnold Z | Methods for treating leukopenia |
US4551550A (en) | 1983-12-06 | 1985-11-05 | Merrell Dow Pharmaceuticals Inc. | N-2,3-Butadienyl-1,4-butanediamine derivatives |
CA1247598A (fr) * | 1984-12-27 | 1988-12-28 | Harry J. Andress, Jr. | Compose derives d'acides mono- et polycarboxyliques renfermant des liaison amides dans la meme molecule; lubrifiants et combustibles qui en contiennent |
CS252771B1 (cs) * | 1986-01-20 | 1987-10-15 | Josef Urbanek | Reakční produkty vyšších nasycených a/nebo nenasycených karboxylových kyselin s polytopickými aminy |
US4889851A (en) | 1986-11-21 | 1989-12-26 | Fujisawa Pharmaceutical Co, Ltd. | Benzothiadiazine compounds, and pharmaceutical composition comprising the same |
US6184232B1 (en) | 1986-12-02 | 2001-02-06 | University Of Florida | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment |
US5342945A (en) | 1986-12-02 | 1994-08-30 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5091576A (en) | 1986-12-02 | 1992-02-25 | University Of Florida | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
USRE38417E1 (en) | 1986-12-02 | 2004-02-03 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5677351A (en) | 1986-12-02 | 1997-10-14 | University Of Florida Research Foundation, Inc. | Sterically hindered tetraamines and method for their production |
US5393757A (en) | 1986-12-02 | 1995-02-28 | University Of Florida | Polyamines and anti-diarrheal and gastrointestinal anti-spasmodic pharmaceutical compositions and methods of treatment |
US5654484A (en) | 1987-10-08 | 1997-08-05 | Merrell Pharmaceuticals Inc. | Polyamine derivatives as antineoplastic agents |
US4868219A (en) | 1988-04-07 | 1989-09-19 | Thornfeldt Carl R | Treatment of skin diseases with aliphatic amines |
CA2011367C (fr) | 1988-08-30 | 1997-07-08 | Henry Ashjian | Produits de reaction d'alkenylsuccinimides avec des acides ethylenediaminecarboxyliques comme detergents de carburant |
US5719193A (en) | 1989-05-23 | 1998-02-17 | Merrell Pharmaceuticals, Inc. | Method of potentiating cell-mediated immunity utilizing polyamine derivatives |
US5283367A (en) | 1989-08-30 | 1994-02-01 | Ciba-Geigy Corporation | Substituted 1,4-diamino-2-butene stabilizers |
JP3007391B2 (ja) | 1990-08-13 | 2000-02-07 | 花王株式会社 | 新規第4級アンモニウム化合物 |
GB9111794D0 (en) | 1991-05-31 | 1991-07-24 | Robins David J | Antifungal compounds |
CZ39994A3 (en) | 1991-08-23 | 1994-11-16 | Pfizer | Synthetic aryl polyamines representing antagonists of excitation amino acid neurotransmitters, process of their preparation and use |
US5185369A (en) | 1991-08-23 | 1993-02-09 | Pfizer Inc. | Synthetic heteroaryl polyamines as excitatory amino acid neurotransmitter antagonists |
US5242684A (en) | 1991-10-25 | 1993-09-07 | Isp Investments Inc. | Antimicrobial, low toxicity, non-irritating composition comprising a blend of bis-quaternary ammonium compounds coprecipitated with a copolymer of vinylpyrrolidone and an acrylamido or vinyl quaternary ammonium monomer |
US6051611A (en) | 1991-11-08 | 2000-04-18 | Alcon Laboratories, Inc. | Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobias |
US5512597A (en) | 1991-11-08 | 1996-04-30 | Alcon Laboratories, Inc. | Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials |
US5530092A (en) | 1992-01-13 | 1996-06-25 | Dsm N.V. | Dendritic macromolecule and the preparation thereof |
GB9220921D0 (en) | 1992-10-05 | 1992-11-18 | Merrell Dow Pharma | Polyamine derivatives as anticytomegaloviral agents |
DE4306152A1 (de) | 1993-02-27 | 1994-09-01 | Hoechst Ag | Positiv arbeitendes strahlungsempfindliches Gemisch und damit hergestelltes Aufzeichnungsmaterial |
US5451347A (en) | 1993-06-24 | 1995-09-19 | Lumigen, Inc. | Methods and compositions providing enhanced chemiluminescence from chemiluminescent compounds using dicationic surfactants |
US5541230A (en) | 1993-11-05 | 1996-07-30 | Us Health | Therapeutic polyamines |
CA2155095A1 (fr) | 1993-12-27 | 1995-07-06 | Jorg Frei | Composes amino insatures destines a etre utilises en tant qu'agents anticancer et antiprotozoose |
DE4403039A1 (de) | 1994-01-28 | 1995-08-03 | Schering Ag | Oktaazamakrocyclen, deren Metallkomplexe, Verfahren zu deren Herstellung, diese Komplexe enthaltende Mittel sowie deren Verwendung in Diagnostik und Therapie |
DK0741756T3 (da) | 1994-01-28 | 1999-02-22 | Dsm Nv | Dendritisk makromolekyle og fremgangsmåde til fremstilling heraf |
JPH07228589A (ja) | 1994-02-16 | 1995-08-29 | Fuji Photo Film Co Ltd | リン酸エステル誘導体およびそれを含有するハロゲン化銀写真感光材料 |
JPH07277964A (ja) | 1994-04-08 | 1995-10-24 | Nippon Kayaku Co Ltd | 抗腫瘍剤 |
JP3805364B2 (ja) | 1994-11-12 | 2006-08-02 | ビーエーエスエフ アクチェンゲゼルシャフト | 少なくとも3個のシアノ基を有する化合物からのアミンの製造法 |
FR2729852A1 (fr) | 1995-01-30 | 1996-08-02 | Oreal | Composition reductrice comprenant un acide amine basique et un polymere cationique |
EP0752465A1 (fr) | 1995-06-01 | 1997-01-08 | The Procter & Gamble Company | Bétaine esters pour administration des alcools |
EP0761680A3 (fr) | 1995-09-12 | 1999-05-06 | Ono Pharmaceutical Co., Ltd. | Composés de tétrazole ayant une activité inhibante d'enzyme convertissant l'Interleukine-1bêta |
US5869715A (en) | 1995-09-27 | 1999-02-09 | The Reagents Of The University Of California | Polyfunctional cationic cytofectins |
US5886051A (en) | 1995-11-08 | 1999-03-23 | University Of Florida Research Foundation, Inc. | Methods and compositions for the treatment of neurodegeneration |
US6126964A (en) | 1996-01-04 | 2000-10-03 | Mirus Corporation | Process of making a compound by forming a polymer from a template drug |
US5962533A (en) * | 1996-02-06 | 1999-10-05 | University Of Florida Research Foundation, Inc. | Hydroxy polyamines |
JP3939355B2 (ja) | 1996-02-07 | 2007-07-04 | バックマン・ラボラトリーズ・インターナショナル・インコーポレーテッド | イオネンポリマーおよびドデシルアミン塩を含有する相乗的殺菌剤組成物ならびにその使用方法 |
DE19621510A1 (de) | 1996-05-29 | 1997-12-04 | Basf Ag | Dendritische stickstoffhaltige organische Verbindungen mit planar-chiralen oder axial-chiralen Endgruppen, ihre Herstellung und Verwendung |
US6034129A (en) | 1996-06-24 | 2000-03-07 | Geltex Pharmaceuticals, Inc. | Ionic polymers as anti-infective agents |
DE19625982A1 (de) | 1996-06-28 | 1998-01-02 | Wella Ag | Kosmetisches Mittel zur Haarbehandlung mit Dendrimeren |
US5866016A (en) | 1997-07-01 | 1999-02-02 | Buckman Laboratories International, Inc. | Methods and compositions for controlling biofouling using combinations of an ionene polymer and a salt of dodecylamine |
US5958397A (en) | 1996-07-22 | 1999-09-28 | Schering-Plough Healthcare Products, Inc. | Method and composition for protecting against jellyfish stings |
US5906996A (en) | 1996-08-21 | 1999-05-25 | Murphy; Michael A. | Tetramine treatment of neurological disorders |
WO1998010766A1 (fr) | 1996-09-13 | 1998-03-19 | University Of Florida Research Foundation, Inc. | PROCEDE INHIBANT LA BIOSYNTHESE DE L'EIf5A |
WO1998017747A1 (fr) | 1996-10-22 | 1998-04-30 | Tonen Corporation | Composition d'huile lubrifiante pour transmissions automatiques |
US6235794B1 (en) | 1997-04-03 | 2001-05-22 | University Of Florida | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment |
US6307102B1 (en) | 1997-10-15 | 2001-10-23 | Tosoh Corporation | Amine catalyst for producing polyurethane and polyisocyanurate |
US6046282A (en) | 1998-01-06 | 2000-04-04 | Air Products And Chemicals, Inc. | Reactive diluents for polyamidoamine epoxy curatives |
CA2321200A1 (fr) | 1998-02-27 | 1999-09-02 | Dnavec Research Inc. | Compositions pour transporter des substances chargees negativement |
JP3996274B2 (ja) | 1998-07-07 | 2007-10-24 | 電気化学工業株式会社 | モノビニルアセチレンの製造方法 |
US6531512B1 (en) | 1998-07-31 | 2003-03-11 | Health Research Inc. | Method of treating cancer in patients having a deficiency in p53 tumor suppressor gene |
AU1180300A (en) | 1998-11-16 | 2000-06-05 | Rohto Pharmaceutical Co., Ltd. | Liquid ophthalmic preparations |
JP3747355B2 (ja) | 1998-12-21 | 2006-02-22 | 独立行政法人理化学研究所 | 鎖状ポリアミン系化合物及びポリアミン系抗ガン剤 |
US6649587B1 (en) | 1999-04-30 | 2003-11-18 | Slil Biomedical Corporation | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
JP2002543163A (ja) | 1999-04-30 | 2002-12-17 | スリル バイオメディカル コーポレイション | 癌および前立腺疾患のための治療としての結合体 |
US6673890B1 (en) | 1999-07-16 | 2004-01-06 | Basf Aktiengesellschaft | Zwitterionic polyamines and process for their production |
GB9920107D0 (en) | 1999-08-26 | 1999-10-27 | Avecia Ltd | Fluidising agents |
JP2001131449A (ja) | 1999-11-01 | 2001-05-15 | Matsushita Electric Ind Co Ltd | インクジェット記録用インク |
FR2802817B1 (fr) | 1999-12-23 | 2002-10-11 | Centre Nat Rech Scient | Nouveaux inhibiteurs de glycosidases et leurs applications pharmacologiques, notamment pour traiter le diabete |
ATE361744T1 (de) | 2000-01-10 | 2007-06-15 | Zetetic Res Inc | Verwendung einer pharmazeutischen zusammensetzung enthaltend zwei quaternäre ammoniumverbindungen und eine organometal-verbindung zur behandlung von viralen und fungalen infekten und krankheiten |
US6444707B1 (en) | 2000-08-22 | 2002-09-03 | West Agro | Topically applied hoof treatment composition and concentrate |
CA2422531C (fr) | 2000-09-19 | 2011-03-08 | Dermal Therapy (Barbados) Inc. | Compositions analgesiques topiques contenant des polyamines aliphatiques et modalites d'utilisation |
US6545181B1 (en) | 2000-10-24 | 2003-04-08 | Pilot Chemical Holdings, Inc. | Demulsifying compound and a method of breaking or inhibiting emulsions |
JP2004513136A (ja) | 2000-11-08 | 2004-04-30 | スリル バイオメディカル コーポレーション | 抗癌剤として有用な新規ポリアミンアナログ−アミノ酸結合体 |
US7754765B2 (en) | 2000-12-01 | 2010-07-13 | Radical Vision Therapeutics Inc | Copper chelators for treating ocular inflammation |
DE60132494T2 (de) | 2000-12-01 | 2008-12-24 | Radical Vision Therapeutics Inc. | Kupferchelatbildner zur behandlung von augenentzündungen |
US6399662B1 (en) | 2000-12-13 | 2002-06-04 | University Of Florida | Method and composition for the treatment of diarrhea and gastrointestinal spasms |
US6635679B2 (en) | 2001-05-14 | 2003-10-21 | Akzo Nobel N.V. | Methods and compositions for inactivating viruses |
US6713653B2 (en) | 2001-08-24 | 2004-03-30 | E. I. Du Pont De Nemours And Company | Polyamines and polymers made therewith |
EP1436246A1 (fr) | 2001-10-16 | 2004-07-14 | SLIL Biomedical Corporation | Composes oligoamine et leurs derives pour le traitement des cancers |
US6458795B1 (en) | 2001-11-15 | 2002-10-01 | University Of Florida | Method and composition for treatment of irritable bowel disease |
JP2005510524A (ja) | 2001-11-16 | 2005-04-21 | アルス・セラピー・デベロツプメント・フアンデーシヨン・インコーポレーテツド | ポリアミン経路の調節による神経変性障害の治療 |
AU2003210883A1 (en) | 2002-02-07 | 2003-09-02 | Wisconsin Alumni Research Foundation | Polyamine compounds and compositions for use in conjunction with cancer therapy |
US6881732B2 (en) | 2002-06-13 | 2005-04-19 | Chelator Llc | Neuroprotection and cardioprotection afforded by chelators with high affinity and specificity for cations of first transition series elements |
US20040019043A1 (en) | 2002-07-23 | 2004-01-29 | Dimitri Coucouvanis | Thiomolybdate analogues and uses thereof |
US7189865B2 (en) | 2002-07-23 | 2007-03-13 | Attenuon, Llc | Thiomolybdate analogues and uses thereof |
-
2002
- 2002-10-16 EP EP02778572A patent/EP1436246A1/fr not_active Withdrawn
- 2002-10-16 US US10/272,269 patent/US20030130356A1/en not_active Abandoned
- 2002-10-16 JP JP2003536196A patent/JP2005506354A/ja active Pending
- 2002-10-16 CA CA002463771A patent/CA2463771A1/fr not_active Abandoned
- 2002-10-16 WO PCT/US2002/032932 patent/WO2003033455A1/fr active Application Filing
- 2002-10-16 IL IL16142802A patent/IL161428A0/xx unknown
- 2002-10-16 AU AU2002340224A patent/AU2002340224B2/en not_active Ceased
-
2004
- 2004-10-01 US US10/957,105 patent/US7491849B2/en not_active Expired - Fee Related
-
2009
- 2009-01-21 US US12/357,323 patent/US20090124832A1/en not_active Abandoned
- 2009-02-18 AU AU2009200639A patent/AU2009200639A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2002340224B2 (en) | 2008-11-27 |
AU2009200639A1 (en) | 2009-03-12 |
US7491849B2 (en) | 2009-02-17 |
EP1436246A1 (fr) | 2004-07-14 |
WO2003033455A1 (fr) | 2003-04-24 |
US20090124832A1 (en) | 2009-05-14 |
JP2005506354A (ja) | 2005-03-03 |
CA2463771A1 (fr) | 2003-04-24 |
US20050080144A1 (en) | 2005-04-14 |
US20030130356A1 (en) | 2003-07-10 |
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