JP2005502061A5 - - Google Patents

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JP2005502061A5
JP2005502061A5 JP2003526515A JP2003526515A JP2005502061A5 JP 2005502061 A5 JP2005502061 A5 JP 2005502061A5 JP 2003526515 A JP2003526515 A JP 2003526515A JP 2003526515 A JP2003526515 A JP 2003526515A JP 2005502061 A5 JP2005502061 A5 JP 2005502061A5
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Japan
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particles
porous
group
hybrid
surface modifier
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JP2003526515A
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JP2005502061A (ja
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Priority claimed from US09/924,399 external-priority patent/US6686035B2/en
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JP2003526515A 2001-08-07 2002-08-07 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法 Pending JP2005502061A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/924,399 US6686035B2 (en) 1999-02-05 2001-08-07 Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
PCT/US2002/025250 WO2003022392A1 (en) 2001-08-07 2002-08-07 Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation

Related Child Applications (1)

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JP2008231653A Division JP4943396B2 (ja) 2001-08-07 2008-09-10 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法

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JP2005502061A JP2005502061A (ja) 2005-01-20
JP2005502061A5 true JP2005502061A5 (https=) 2006-01-05

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JP2003526515A Pending JP2005502061A (ja) 2001-08-07 2002-08-07 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法
JP2008231653A Expired - Fee Related JP4943396B2 (ja) 2001-08-07 2008-09-10 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法

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JP2008231653A Expired - Fee Related JP4943396B2 (ja) 2001-08-07 2008-09-10 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法

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US (5) US6686035B2 (https=)
EP (1) EP1450924A4 (https=)
JP (2) JP2005502061A (https=)
WO (1) WO2003022392A1 (https=)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7232520B1 (en) 1998-06-12 2007-06-19 Waters Investments Limited Ion exchange porous resins for solid phase extraction and chromatography
AU4437399A (en) * 1998-06-12 1999-12-30 Waters Investments Limited Novel ion exchange porous resins for solid phase extraction and chromatography
US6686035B2 (en) * 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
US6528167B2 (en) * 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
US20090056541A1 (en) * 2001-08-01 2009-03-05 Davison Dale A Method and apparatus for high resolution flash chromatography
US7250214B2 (en) * 2001-08-09 2007-07-31 Waters Investments Limited Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation
WO2003078159A1 (en) * 2002-03-13 2003-09-25 Regents Of The University Of Minnesota Silica-based materials and methods
US20040211724A1 (en) * 2002-10-01 2004-10-28 Gibson Gary L. Method of separating components in a sample using silane-treated silica filter media
US7264728B2 (en) * 2002-10-01 2007-09-04 Dow Corning Corporation Method of separating components in a sample using silane-treated silica filter media
WO2004041398A2 (en) * 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
JP4791352B2 (ja) 2003-02-07 2011-10-12 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフィーナノカラム用ポリマー固体支持体
US20060219636A1 (en) * 2003-02-10 2006-10-05 Waters Investments Limited Siloxane-immobilized particulate stationary phases for chromatographic separations and extractions
DE112004000906T5 (de) * 2003-05-28 2006-10-19 Waters Investments Ltd., New Castle Neue Nanoverbundstoffe und ihre Anwendung als Monolithsäulen
US20060035054A1 (en) * 2004-01-05 2006-02-16 Aspen Aerogels, Inc. High performance vacuum-sealed insulations
AU2005204368A1 (en) * 2004-01-06 2005-07-28 Aspen Aerogels, Inc. Ormosil aerogels containing silicon bonded linear polymers
EP1714195A2 (en) * 2004-01-06 2006-10-25 Aspen Aerogels Inc. Ormosil aerogels containing silicon bonded polymethacrylate
DE112005000269T5 (de) * 2004-02-17 2007-01-25 Waters Investments Ltd., New Castle Poröse Hybridmonolithmaterialien mit von der Oberfläche entfernten organischen Gruppen
US7309426B2 (en) * 2004-04-23 2007-12-18 Agilent Technologies, Inc. Composition and method for high efficiency chromatography
US20060019084A1 (en) * 2004-07-23 2006-01-26 Pearson Laurence T Monolithic composition and method
DE112005001838B4 (de) * 2004-07-30 2018-11-29 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Poröse anorganische/organische Hybridmaterialien mit geordneten Domänen für chromatographische Auftrennungen, Verfahren für deren Herstellung sowie Auftrennvorrichtung und chromatographische Säule
US10773186B2 (en) 2004-07-30 2020-09-15 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
US7312175B2 (en) * 2004-08-18 2007-12-25 Battelle Energy Alliance, Llc Ion exchange materials, method of forming ion exchange materials, and methods of treating liquids
JP2008511537A (ja) * 2004-09-01 2008-04-17 アスペン エアロジェルス，インク． 真空封入された高性能断熱材
WO2006039507A2 (en) * 2004-10-01 2006-04-13 Phenomenex, Inc. Ph stable chromatographic media using templated multilayer organic/inorganic grafting
US9125968B2 (en) * 2005-03-30 2015-09-08 Boston Scientific Scimed, Inc. Polymeric/ceramic composite materials for use in medical devices
US20070014699A1 (en) 2005-06-23 2007-01-18 Beckman Coulter, Inc, Methods and apparatus for improving the sensitivity of capillary zone electrophoresis
US8008395B2 (en) * 2005-09-27 2011-08-30 Boston Scientific Scimed, Inc. Organic-inorganic hybrid particle material and polymer compositions containing same
US9440869B2 (en) 2005-09-30 2016-09-13 Abs Materials, Inc. Sol-gel derived compositions
US7790830B2 (en) * 2005-09-30 2010-09-07 Wootech, Ltd. Swellable sol-gels, methods of making, and use thereof
US20100113856A1 (en) * 2005-09-30 2010-05-06 Absorbent Materials Company Llc Apparatus and method for remediation of aqueous solutions
US8367793B2 (en) * 2005-09-30 2013-02-05 Abs Materials, Inc. Swellable materials and methods of use
US20100108612A1 (en) * 2005-09-30 2010-05-06 Absorbent Materials Company Llc Apparatus and method for removing small molecule organic pharmaceuticals from aqueous solutions
US9144784B2 (en) 2005-09-30 2015-09-29 Abs Materials Sorbent material and method for using the same
US20070089604A1 (en) * 2005-10-20 2007-04-26 Wu Chen Novel chromatographic stationary phase
US9308520B2 (en) 2005-12-16 2016-04-12 Akzo Nobel N.V. Silica based material
KR20070079867A (ko) * 2006-02-04 2007-08-08 삼성전자주식회사 유-무기 하이브리드 중합체 및 이를 포함하는 유기 절연체조성물
WO2007092827A2 (en) * 2006-02-08 2007-08-16 Waters Investments Limited Improved separation method
US7947579B2 (en) * 2006-02-13 2011-05-24 Stc.Unm Method of making dense, conformal, ultra-thin cap layers for nanoporous low-k ILD by plasma assisted atomic layer deposition
US8187678B2 (en) * 2006-02-13 2012-05-29 Stc.Unm Ultra-thin microporous/hybrid materials
JP4962490B2 (ja) * 2006-03-29 2012-06-27 ダイソー株式会社 修飾シリカゲル及びその利用
US9181486B2 (en) 2006-05-25 2015-11-10 Aspen Aerogels, Inc. Aerogel compositions with enhanced performance
WO2008035125A2 (en) * 2006-09-22 2008-03-27 Analytical Nano Technologies Limited Methods
DE102006058200A1 (de) * 2006-12-11 2008-06-12 Merck Patent Gmbh Redispergierbare oberflächenmodifizierte Partikel
JP2010515804A (ja) * 2007-01-12 2010-05-13 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフ分離用多孔質炭素−ヘテロ原子−ケイ素ハイブリッド無機／有機材料およびその調製のための方法
EP2150402A4 (en) * 2007-02-21 2013-07-10 Waters Technologies Corp POROUS INORGANIC / ORGANIC HYBRID PARTICLES WITH ORGANIC CONTENTS AND IMPROVED PORENEGOMETRY FOR CHROMATOGRAPHIC SEPARATIONS
WO2008140996A1 (en) 2007-05-08 2008-11-20 Waters Investments Limited Chromatographic and electrophoretic separation media and apparatus
EP2212319B1 (en) 2007-10-31 2018-07-18 Alseres Pharmaceuticals, Inc. Labeled iodinated tropane formulation
US8314201B2 (en) 2007-11-30 2012-11-20 The United States Of America As Represented By The Administration Of The National Aeronautics And Space Administration Highly porous ceramic oxide aerogels having improved flexibility
US8258251B2 (en) * 2007-11-30 2012-09-04 The United States Of America, As Represented By The Administrator Of The National Aeronautics And Space Administration Highly porous ceramic oxide aerogels having improved flexibility
KR20100111681A (ko) * 2007-12-19 2010-10-15 쓰리엠 이노베이티브 프로퍼티즈 컴파니 정밀-성형된 다공성 입자
EP2247933B1 (en) * 2008-02-25 2019-11-06 Waters Technologies Corporation Methods for the determination of the presence and quantity of vitamin d analogs in samples
KR101259015B1 (ko) * 2008-02-29 2013-04-29 삼성전자주식회사 재생 방법 및 장치
WO2009126207A1 (en) * 2008-04-08 2009-10-15 Waters Technologies Corporation Composite materials containing nanoparticles and their use in chromatography
US8277883B2 (en) * 2008-06-13 2012-10-02 Agilent Technologies, Inc. Porous silica microspheres having organosilane modified surfaces
US8685283B2 (en) 2008-08-29 2014-04-01 Agilent Technologies, Inc. Superficially porous metal oxide particles, methods for making them, and separation devices using them
US8357628B2 (en) 2008-08-29 2013-01-22 Agilent Technologies, Inc. Inorganic/organic hybrid totally porous metal oxide particles, methods for making them and separation devices using them
US9284456B2 (en) 2008-08-29 2016-03-15 Agilent Technologies, Inc. Superficially porous metal oxide particles, methods for making them, and separation devices using them
BRPI1009421A2 (pt) * 2009-03-12 2016-03-01 Shiseido Co Ltd método para a fabricação de material de recheio, material de recheio e coluna
WO2010141426A1 (en) * 2009-06-01 2010-12-09 Waters Technologies Corporation Hybrid material for chromatographic separations
US11439977B2 (en) 2009-06-01 2022-09-13 Waters Technologies Corporation Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material
JP6125230B2 (ja) 2009-08-04 2017-05-10 ウオーターズ・テクノロジーズ・コーポレイシヨン イオン性修飾剤を含有する高純度クロマトグラフィー材料
US20130135610A1 (en) 2009-12-15 2013-05-30 Waters Technologies Corporation Device and methods for performing size exclusion chromatography
US20130012379A1 (en) * 2010-01-08 2013-01-10 Abs Materials, Inc. Modified sol-gel derived sorbent material and method for using the same
WO2011149041A1 (ja) 2010-05-27 2011-12-01 ダイセル化学工業株式会社 薄層クロマトグラフィーによる試料の検出方法、薄層クロマトグラフィープレート、及びその製造方法
US20130112605A1 (en) 2010-07-26 2013-05-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
WO2012112553A1 (en) 2011-02-14 2012-08-23 Dionex Corporation Nanometer size chemical modified materials and uses
JP6189752B2 (ja) 2011-02-16 2017-08-30 ウオーターズ・テクノロジーズ・コーポレイシヨン 固定化酵素反応器
US10258979B2 (en) 2011-05-20 2019-04-16 Waters Technologies Corporation Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof
CN102320819A (zh) * 2011-05-23 2012-01-18 江苏红旗环保工程有限公司 规整波纹陶瓷填料及其制备方法
AU2012290005A1 (en) * 2011-08-02 2014-02-20 Abs Materials, Inc. Sol-gel derived compositions
WO2013078450A1 (en) * 2011-11-23 2013-05-30 Momentive Performance Materials, Inc. Process for making organic-inorganic hybrid materials
EP2794621B1 (en) 2011-12-23 2018-09-26 Universiteit Gent Novel organosilica compounds
WO2013173501A2 (en) 2012-05-15 2013-11-21 Waters Technologies Corporation Chromatographic materials
EP2812091B1 (en) 2012-09-17 2021-03-10 W.R. Grace & CO. - CONN. Chromatography media and devices
US9610576B2 (en) 2012-09-27 2017-04-04 Agilent Technologies, Inc. Hydrolytically stable ion-exchange stationary phases and uses thereof
US9702856B2 (en) * 2012-10-03 2017-07-11 Waters Technologies Corporation System and method for rapid analysis of polymer additives
FR2998891B1 (fr) * 2012-11-30 2015-04-10 Commissariat Energie Atomique Procede pour preparer un verre a porosite bimodale, eventuellement fonctionnalise et ledit verre
RU2527217C1 (ru) * 2012-12-27 2014-08-27 Александр Валерианович Пастухов Способ получения полимер-неорганических композитных сорбентов
WO2014201033A1 (en) 2013-06-11 2014-12-18 Waters Technologies Corporation Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography
US9518960B2 (en) * 2013-10-02 2016-12-13 Waters Technologies Corporation System and method for rapid analysis of polycyclic aromatic hydrocarbons
US11092574B2 (en) 2013-12-24 2021-08-17 Waters Technologies Corporation Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
US10119944B2 (en) 2013-12-24 2018-11-06 Waters Technologies Corporation Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
US20150224473A1 (en) 2014-02-07 2015-08-13 Thermo Electron Manufacturing Limited Chromatographic material and methods for the synthesis thereof
PL3137209T3 (pl) 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego
KR102566292B1 (ko) 2015-06-05 2023-08-10 더블유.알. 그레이스 앤드 캄파니-콘. 흡착성 바이오프로세싱 정화제와 이의 제조 및 사용 방법
JP6857604B2 (ja) * 2015-08-25 2021-04-14 昭和電工株式会社 液体クロマトグラフィー用カラム及びそれを備えた液体クロマトグラフ装置
EP3377110B1 (en) 2015-11-20 2021-01-06 AbbVie Deutschland GmbH & Co. KG Nanoparticles based on optionally alkoxylated poly(alkyl cyanoacrylates) having a defined degree of polymerization
US20190015815A1 (en) 2016-03-06 2019-01-17 Waters Technologies Corporation Superficially porous materials comprising a coated core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
US10434496B2 (en) 2016-03-29 2019-10-08 Agilent Technologies, Inc. Superficially porous particles with dual pore structure and methods for making the same
US10501432B2 (en) 2016-04-01 2019-12-10 Waters Technologies Corporation Chiral separation of Δ8-THC, Δ9-THC, and related enantiomers using CO2-based chromatography
JP7005515B2 (ja) 2016-04-24 2022-02-10 ウオーターズ・テクノロジーズ・コーポレイシヨン 荷電表面逆相クロマトグラフィ材料による両親媒性強塩基性部分で修飾されたグリカンの分析方法
US10618920B2 (en) * 2016-06-03 2020-04-14 Agilent Technologies, Inc. Functionalized particles having modified phases
US11280766B2 (en) 2016-07-28 2022-03-22 Waters Technologies Corporation Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis
US11092577B2 (en) 2017-03-08 2021-08-17 Waters Technologies Corporation Polar pesticide determination using chromatography
US9925515B1 (en) * 2017-03-24 2018-03-27 The Florida International University Board Of Trustees Alkyl functionalized porous silica liquid chromatographic stationary phases and solid phase extraction sorbents
US11709156B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved analytical analysis
US11709155B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US12181452B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US12180581B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US20190126241A1 (en) 2017-09-26 2019-05-02 Waters Technologies Corporation High purity chromatographic materials comprising an ionizable modifier for retention of acidic analytes
WO2019067632A1 (en) 2017-09-26 2019-04-04 Waters Technologies Corporation LIQUID CHROMATOGRAPHY SEPARATION OF GLUCIDIC TAUTOMERS
CN112261976A (zh) 2018-06-12 2021-01-22 沃特世科技公司 生物分子的尺寸排阻色谱法
EP3821238B1 (en) 2018-07-11 2022-08-31 Waters Technologies Corporation Chromatographic system and method for trap-elute mixed mode chromatography
US11307183B2 (en) 2018-07-18 2022-04-19 Waters Technologies Corporation Methods for determination of polar pesticides by chromatography
EP4509831A3 (en) 2018-07-27 2025-03-19 Waters Technologies Corporation Liquid chromatography/mass spectrometry methods for the analysis of polar molecules
US11376561B2 (en) 2018-10-02 2022-07-05 Waters Technologies Corporation Sorbent particles for sample treatment
KR102716678B1 (ko) * 2019-05-15 2024-10-15 주식회사 엘지화학 산화방지제의 고속 분리 및 분석을 위한 방법 및 시스템
US20210138361A1 (en) 2019-11-07 2021-05-13 Waters Technologies Corporation Materials and methods for mixed mode, anion exchange reversed phase liquid chromatography
EP4070102A1 (en) 2019-12-05 2022-10-12 Waters Technologies Corporation Polyphosphonic acids for improving recovery and minimizing system loss
CN111036526B (zh) * 2019-12-31 2022-04-29 丹阳双峰玻璃有限公司 一种安全覆硅胶膜玻璃奶瓶生产工艺
US11918936B2 (en) 2020-01-17 2024-03-05 Waters Technologies Corporation Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding
EP4121203A1 (en) 2020-03-20 2023-01-25 Restek Corporation Spike particles, superficially porous spike particles, chromatographic separation devices, and processes for forming spike particles
US11951417B2 (en) 2020-04-15 2024-04-09 Waters Technologies Corporation SEC performance enhancing conditioning and storage solvents containing low levels of buffer and salt
US12332224B2 (en) 2020-04-15 2025-06-17 Waters Technolgies Corporation Guard column configurations for size exclusion chromatography separations
US11964874B2 (en) 2020-06-09 2024-04-23 Agilent Technologies, Inc. Etched non-porous particles and method of producing thereof
EP4182460A1 (en) 2020-07-14 2023-05-24 Waters Technologies Corporation Kits and methods useful for separating oligonucleotides from matrix components
WO2022061035A1 (en) 2020-09-16 2022-03-24 Waters Technologies Corporation Improved size exclusion chromatography utilizing low concentration amino acids in size exclusion chromatography mobile phase
CN116209517A (zh) 2020-09-16 2023-06-02 沃特世科技公司 具有羟基封端的peg键合和甲氧基封端的peg表面改性的基于二氧化硅的颗粒
US12352734B2 (en) 2020-09-24 2025-07-08 Waters Technologies Corporation Chromatographic hardware improvements for separation of reactive molecules
CN116322921B (zh) 2020-10-16 2026-04-21 沃特世科技公司 包括用于尺寸排阻色谱法的亲水性非离子涂层的改进装置
CA3207750A1 (en) 2020-12-11 2022-06-16 Genentech, Inc. Methods for determining the relative distribution of glucuronidation, iduronidation, and galacturonidation of polypeptides
CN117222480A (zh) * 2021-04-29 2023-12-12 沃特世科技公司 水解稳定的两性离子色谱材料
CN117396754A (zh) 2021-06-04 2024-01-12 沃特世科技公司 核酸组分化合物在两性离子固定相上的分离
WO2023026258A1 (en) 2021-08-26 2023-03-02 Waters Technologies Corporation Core-shell particles with organic polymer cores
US12551864B2 (en) 2021-11-19 2026-02-17 Waters Technologies Corporation Double surface modified porous material with minimized nonspecific interaction
EP4479156A1 (en) 2022-02-19 2024-12-25 Waters Technologies Corporation Novel size exclusion chromatography column technologies for analysis of crispr molecules
US12478949B2 (en) 2022-08-26 2025-11-25 Waters Technologies Corporation Composite particles with non-porous hybrid organic-inorganic material
WO2024042373A1 (en) 2022-08-26 2024-02-29 Waters Technologies Corporation Core-shell particles having a non-porous core and a porous shell
CN119744199A (zh) 2022-08-26 2025-04-01 沃特世科技公司 无孔杂化涂覆聚合物颗粒
WO2024042372A1 (en) 2022-08-26 2024-02-29 Waters Technologies Corporation Bonded hybrid polymer non-porous particles and their use for bioseparations
US20240139713A1 (en) 2022-10-31 2024-05-02 Waters Technologies Corporation Multi-component surface chemistry to eliminate retention loss in reversed-phase liquid chromatography
CN120513126A (zh) 2023-01-11 2025-08-19 沃特世科技公司 用于固相萃取的双足硅烷结合的吸附剂及其用于寡核苷酸萃取的用途
US20240241095A1 (en) * 2023-01-12 2024-07-18 Agilent Technologies, Inc. Chromatography column for the separation of surfactants
WO2024178406A2 (en) * 2023-02-25 2024-08-29 Chrom6 Technologies, LLC Carbon microsphere chromatographic material
CN121127312A (zh) 2023-05-05 2025-12-12 沃特世科技公司 用于亲和色谱的蛋白a/g颗粒及其使用方法
US20250270538A1 (en) 2024-02-28 2025-08-28 Waters Technologies Corporation Methods for the separation of nucleic acids with slalom chromatography
US20250283860A1 (en) 2024-03-08 2025-09-11 Waters Technologies Corporation Methods for chromatographic characterization of lipid nanoparticle compositions
US20250298009A1 (en) 2024-03-22 2025-09-25 Waters Technologies Corporation Methods for characterizing lipid nanoparticle compositions
US20250327777A1 (en) 2024-04-19 2025-10-23 Waters Technologies Corporation Dextran improves the sizing analysis of lipid nanoparticles during size exclusion chromatography analysis
WO2025250776A1 (en) * 2024-05-29 2025-12-04 Advanced Materials Technologies, Inc. A ph stable chromatographic material and method of producing the same
WO2025255028A1 (en) 2024-06-03 2025-12-11 Amgen Inc. High-throughput liquid chromatography-mass spectrometry-based peptide mapping

Family Cites Families (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US127177A (en) * 1872-05-28 Improvement in swivels for rock and well boring machines
US3935299A (en) 1972-05-11 1976-01-27 Andrei Vladimirovich Kiselev Process for preparation of wide-pore adsorbent for use in chromatography
DE2236862C2 (de) 1972-07-27 1974-09-05 Istvan Prof. Dr. 6600 Saarbruecken Halasz Sorptionsmittel für die Chromatographie
DE2357184A1 (de) 1973-11-16 1975-05-22 Merck Patent Gmbh Verfahren zur herstellung von organisch modifizierten siliciumdioxiden
US4029583A (en) * 1975-02-28 1977-06-14 Purdue Research Foundation Chromatographic supports and methods and apparatus for preparing the same
CS179184B1 (en) 1975-07-25 1977-10-31 Stanislav Vozka Method for preparation of precisely spherical particles of silica gel with controlled size and controled size pores.
DE2642032C2 (de) 1976-09-18 1987-04-30 Rupprecht, Herbert, Prof. Dr., 8400 Regensburg Verfahren zur Inkorporierung von Wirkstoffen in siliciumdioxidhaltige Trägermaterialien und eine siliciumdioxidhaltige Zubereitung
FR2464967A1 (fr) * 1979-09-07 1981-03-20 Rhone Poulenc Ind Preparation de resines echangeuses d'anions par bromation de polymeres vinylaromatiques
US4324689A (en) * 1980-02-26 1982-04-13 Shah Ramesh M High carbon content chromatographic packing and method for making same
US4334118A (en) * 1981-06-01 1982-06-08 Chevron Research Solid phosphoric acid catalyzed olefin polymerization process
JPS58120525A (ja) 1982-01-05 1983-07-18 Asahi Glass Co Ltd 珪酸塩中空球の製造方法
JPS5954619A (ja) 1982-09-24 1984-03-29 Asahi Glass Co Ltd 珪酸塩粒状体の製造方法
US4724207A (en) 1984-02-02 1988-02-09 Cuno Incorporated Modified siliceous chromatographic supports
JPS60257358A (ja) * 1984-06-05 1985-12-19 Daicel Chem Ind Ltd 分離用充填剤
US5177128A (en) * 1985-07-10 1993-01-05 Sequa Chemicals, Inc. Paper coating composition
DE3616133A1 (de) 1985-09-25 1987-11-19 Merck Patent Gmbh Kugelfoermige sio(pfeil abwaerts)2(pfeil abwaerts)-partikel
US5108595A (en) 1985-11-01 1992-04-28 E. I. Du Pont De Nemours And Company Porous silica microspheres having silanol-enriched and silanized surfaces
GB8618322D0 (en) 1986-07-28 1986-09-03 3I Res Expl Ltd Bonded chromotographic stationary phase
US5256386A (en) 1987-06-29 1993-10-26 Eka Nobel Ab Method for preparation of silica particles
US4889632A (en) * 1987-12-10 1989-12-26 Ceskoslovenska Akademie Ved Macroporous polymeric membranes for the separation of polymers and a method of their application
EP0386926A3 (en) 1989-03-02 1991-12-18 Supelco, Inc. Silica gel supports suitable for chromatographic separations
US5403908A (en) * 1989-10-06 1995-04-04 Idemitsu Kosan Company, Limited Aryl styrene-based copolymer
US6022902A (en) * 1989-10-31 2000-02-08 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Porous article with surface functionality and method for preparing same
US4983369A (en) 1989-11-22 1991-01-08 Allied-Signal Inc. Process for forming highly uniform silica spheres
US5068387A (en) 1989-12-01 1991-11-26 Dow Corning Corporation Production of organofunctional alkoxysilanes
JP2874297B2 (ja) 1989-12-18 1999-03-24 東ソー株式会社 逆相クロマトグラフィー用充填剤及びその製造方法
US5271833A (en) * 1990-03-22 1993-12-21 Regents Of The University Of Minnesota Polymer-coated carbon-clad inorganic oxide particles
JP2646150B2 (ja) 1990-08-27 1997-08-25 出光興産 株式会社 撥水性シリカゾルおよびその製造方法
JPH0617476B2 (ja) * 1990-09-04 1994-03-09 工業技術院長 有機基修飾シリカ粒子、その製造方法および該粒子をフィラーとする樹脂組成物
JPH04210227A (ja) * 1990-12-10 1992-07-31 Res Dev Corp Of Japan 細孔構造を制御した有機シリカ多孔体及びシリカ多孔体の製造方法
US5071565A (en) 1991-02-04 1991-12-10 Iowa State University Research Foundation, Inc. Modified resins for solid-phase extraction
JP3168006B2 (ja) * 1991-10-21 2001-05-21 コーネル・リサーチ・フアウンデーシヨン・インコーポレーテツド マクロ細孔ポリマー媒体が備わっているカラム
US5734020A (en) 1991-11-20 1998-03-31 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5565142A (en) 1992-04-01 1996-10-15 Deshpande; Ravindra Preparation of high porosity xerogels by chemical surface modification.
WO1993023333A1 (en) 1992-05-20 1993-11-25 E.I. Du Pont De Nemours And Company Process for making inorganic gels
JP3440486B2 (ja) 1992-06-19 2003-08-25 旭硝子株式会社 球状シリカの製造方法
US5298833A (en) * 1992-06-22 1994-03-29 Copytele, Inc. Black electrophoretic particles for an electrophoretic image display
US5374755A (en) 1992-07-17 1994-12-20 Millipore Corporation Liquid chromatography stationary phases with reduced silanol interactions
US5378790A (en) * 1992-09-16 1995-01-03 E. I. Du Pont De Nemours & Co. Single component inorganic/organic network materials and precursors thereof
US5498678A (en) 1992-12-21 1996-03-12 Rohm And Haas Company Suspension polymerization process for water-soluble monomers
EP0710219B1 (en) 1993-07-19 1997-12-10 MERCK PATENT GmbH Inorganic porous material and process for making same
US5425930A (en) 1993-09-17 1995-06-20 Alliedsignal Inc. Process for forming large silica spheres by low temperature nucleation
JPH07113011A (ja) * 1993-10-18 1995-05-02 Nippon Sheet Glass Co Ltd 多孔質体及びこれを充填材とするカラム及びこれらの製造方法
EP0652245B2 (en) * 1993-11-05 2005-02-09 Shin-Etsu Chemical Co., Ltd. Process for preparing organic functional group-containing organopolysiloxanes, organopolysiloxanes obtained by the process and mercapto group and alkoxy group-containing organopolysiloxanes and preparation thereof
JP2893104B2 (ja) 1994-03-14 1999-05-17 直弘 曽我 有機官能基の結合した無機系多孔質体の製造方法
US5728457A (en) * 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
US5868966A (en) * 1995-03-30 1999-02-09 Drexel University Electroactive inorganic organic hybrid materials
US5637135A (en) 1995-06-26 1997-06-10 Capillary Technology Corporation Chromatographic stationary phases and adsorbents from hybrid organic-inorganic sol-gels
US5667674A (en) * 1996-01-11 1997-09-16 Minnesota Mining And Manufacturing Company Adsorption medium and method of preparing same
JP3818689B2 (ja) 1996-01-16 2006-09-06 富士写真フイルム株式会社 コロイド状シリカをコアとし、有機ポリマーをシェルとするコア／シェル状複合粒子の水性分散物及びその製造方法
US5869152A (en) 1996-03-01 1999-02-09 The Research Foundation Of State University Of New York Silica materials
JPH09278485A (ja) 1996-04-11 1997-10-28 Tosoh Corp 耐アルカリ性球状ガラスとその製造方法
US5965202A (en) 1996-05-02 1999-10-12 Lucent Technologies, Inc. Hybrid inorganic-organic composite for use as an interlayer dielectric
US6313219B1 (en) * 1996-05-02 2001-11-06 Lucent Technologies, Inc. Method for hybrid inorganic/organic composite materials
US5853886A (en) * 1996-06-17 1998-12-29 Claytec, Inc. Hybrid nanocomposites comprising layered inorganic material and methods of preparation
AU7533696A (en) * 1996-12-13 1998-06-18 Ciba-Geigy Ag New materials
DE69716126T2 (de) * 1996-12-26 2003-06-05 Merck Patent Gmbh Anorganisches, poröses material und verfahren zu dessen herstellung
US5976479A (en) 1996-12-30 1999-11-02 Uop Llc Hydrothermal process for preparing a unimodal large pore silica
US5935429A (en) 1997-01-03 1999-08-10 Bio-Rad Laboratories, Inc. Chromatography columns with continuous beds formed in situ from aqueous solutions
EP0963414B1 (de) 1997-02-25 2012-07-25 Bayer MaterialScience AG Organisch-anorganische hybridmaterialien
US6380266B1 (en) * 1997-06-13 2002-04-30 California Institute Of Technology Amorphous silica having discrete voids and spatially organized functionalities formed therein
ATE478732T1 (de) 1997-06-18 2010-09-15 Merck Patent Gmbh Verwendung monolithischer sorbentien für präparative chromatographische trennverfahren
US6027643A (en) * 1997-09-04 2000-02-22 Dionex Corporation Ion chromatographic method and apparatus using a combined suppressor and eluent generator
US6136187A (en) * 1997-12-09 2000-10-24 The Board Of Trustees Of The Leland Stanford Junior University Separation column containing porous matrix and method of packing column
WO1999037705A1 (en) 1997-12-09 1999-07-29 The Regents Of The University Of California Block polymer processing for mesostructured inorganic oxide materials
DE19756831A1 (de) * 1997-12-19 1999-07-01 Wacker Chemie Gmbh Siliciumdioxid, das an seiner Oberfläche teil- oder vollständig silylierte Polykieselsäureketten trägt
US6281257B1 (en) * 1998-04-27 2001-08-28 The Regents Of The University Of Michigan Porous composite materials
JP3899733B2 (ja) * 1998-07-03 2007-03-28 株式会社豊田中央研究所 多孔材料及び多孔材料の製造方法
JP3953649B2 (ja) * 1998-07-17 2007-08-08 オリヱント化学工業株式会社 有機−無機ハイブリッド成分傾斜高分子材料、及びその製造方法
US6210570B1 (en) * 1998-08-21 2001-04-03 Agilent Technologies, Inc. Monolithic silica column
US6090477A (en) * 1998-09-11 2000-07-18 Ut-Battelle, Llc Gas storage carbon with enhanced thermal conductivity
US6238565B1 (en) * 1998-09-16 2001-05-29 Varian, Inc. Monolithic matrix for separating bio-organic molecules
DE19856000A1 (de) * 1998-12-04 2000-06-15 Bayer Ag Hybridlack-Zubereitung
US6686035B2 (en) * 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
EP1733786B1 (en) 1999-02-05 2010-04-14 Waters Technologies Corporation Porous hybrid particles for chromatographic separations
US6227304B1 (en) * 1999-03-01 2001-05-08 Case Corporation Upper hitch link
JP4214203B2 (ja) 1999-05-18 2009-01-28 オリヱント化学工業株式会社 有機−無機複合材料およびその製造方法
US20060194919A1 (en) * 1999-08-04 2006-08-31 Lichtenhan Joseph D Porosity control with polyhedral oligomeric silsesquioxanes
US6649083B1 (en) 1999-08-12 2003-11-18 Board Of Trustees Of Michigan State University Combined porous organic and inorganic oxide materials prepared by non-ionic surfactant templating route
SE9903223L (sv) 1999-09-09 2001-05-08 Ericsson Telefon Ab L M Förfarande och anordning i telekommunikationssystem
US6251280B1 (en) * 1999-09-15 2001-06-26 University Of Tennessee Research Corporation Imprint-coating synthesis of selective functionalized ordered mesoporous sorbents for separation and sensors
JP4525879B2 (ja) * 1999-10-14 2010-08-18 戸田工業株式会社 多孔性機能粉体及びその製造法
EP1197998A3 (en) * 2000-10-10 2005-12-21 Shipley Company LLC Antireflective porogens
US6528167B2 (en) 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
US7250214B2 (en) * 2001-08-09 2007-07-31 Waters Investments Limited Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation
WO2004041398A2 (en) 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
DE112005000269T5 (de) 2004-02-17 2007-01-25 Waters Investments Ltd., New Castle Poröse Hybridmonolithmaterialien mit von der Oberfläche entfernten organischen Gruppen
DE112005001838B4 (de) 2004-07-30 2018-11-29 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Poröse anorganische/organische Hybridmaterialien mit geordneten Domänen für chromatographische Auftrennungen, Verfahren für deren Herstellung sowie Auftrennvorrichtung und chromatographische Säule
US7439272B2 (en) * 2004-12-20 2008-10-21 Varian, Inc. Ultraporous sol gel monoliths
JP2010515804A (ja) 2007-01-12 2010-05-13 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフ分離用多孔質炭素−ヘテロ原子−ケイ素ハイブリッド無機／有機材料およびその調製のための方法
EP2150402A4 (en) 2007-02-21 2013-07-10 Waters Technologies Corp POROUS INORGANIC / ORGANIC HYBRID PARTICLES WITH ORGANIC CONTENTS AND IMPROVED PORENEGOMETRY FOR CHROMATOGRAPHIC SEPARATIONS

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