JP2004534788A5 - - Google Patents

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Publication number
JP2004534788A5
JP2004534788A5 JP2003502981A JP2003502981A JP2004534788A5 JP 2004534788 A5 JP2004534788 A5 JP 2004534788A5 JP 2003502981 A JP2003502981 A JP 2003502981A JP 2003502981 A JP2003502981 A JP 2003502981A JP 2004534788 A5 JP2004534788 A5 JP 2004534788A5
Authority
JP
Japan
Prior art keywords
combination
optionally substituted
macrocyclic lactone
receptor
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003502981A
Other languages
English (en)
Japanese (ja)
Other versions
JP4476623B2 (ja
JP2004534788A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2002/006278 external-priority patent/WO2002100148A2/en
Publication of JP2004534788A publication Critical patent/JP2004534788A/ja
Publication of JP2004534788A5 publication Critical patent/JP2004534788A5/ja
Application granted granted Critical
Publication of JP4476623B2 publication Critical patent/JP4476623B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2003502981A 2001-06-08 2002-06-07 インスリン産生細胞移植片拒絶の処置または予防 Expired - Fee Related JP4476623B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29706901P 2001-06-08 2001-06-08
PCT/EP2002/006278 WO2002100148A2 (en) 2001-06-08 2002-06-07 Treatment or prophylaxis of insulin-producing cell graft rejection

Publications (3)

Publication Number Publication Date
JP2004534788A JP2004534788A (ja) 2004-11-18
JP2004534788A5 true JP2004534788A5 (https=) 2005-12-22
JP4476623B2 JP4476623B2 (ja) 2010-06-09

Family

ID=23144725

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003502981A Expired - Fee Related JP4476623B2 (ja) 2001-06-08 2002-06-07 インスリン産生細胞移植片拒絶の処置または予防

Country Status (18)

Country Link
US (5) US20030003099A1 (https=)
EP (1) EP1429845B1 (https=)
JP (1) JP4476623B2 (https=)
CN (1) CN1524002A (https=)
AT (1) ATE424893T1 (https=)
AU (1) AU2002320828B2 (https=)
BR (1) BR0209319A (https=)
CA (1) CA2445605A1 (https=)
DE (1) DE60231522D1 (https=)
ES (1) ES2322442T3 (https=)
IL (1) IL158384A0 (https=)
NO (1) NO20035434D0 (https=)
NZ (1) NZ529044A (https=)
PL (1) PL364359A1 (https=)
PT (1) PT1429845E (https=)
RU (1) RU2003136730A (https=)
WO (1) WO2002100148A2 (https=)
ZA (1) ZA200307893B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4318921B2 (ja) * 2001-02-22 2009-08-26 ノバルティス アクチエンゲゼルシャフト 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用
EP2338511A3 (en) * 2004-05-14 2012-07-25 Alexion Pharmaceuticals, Inc. Prolongation of survival of an allograft by inhibiting complement activity
US7781617B2 (en) * 2004-07-16 2010-08-24 Kyorin Pharmaceutical Co., Ltd Effective use method of medicaments and method of preventing expression of side effect
KR20070085465A (ko) * 2004-11-29 2007-08-27 노파르티스 아게 S1p 수용체 효능제의 투여 용법
CA2595960A1 (en) * 2005-02-08 2006-08-17 Novartis Ag Antilymphocyte antibody induction by combination of an s1p receptor agonist/modulator and of immunosuppressive drugs
US8778327B2 (en) * 2005-05-11 2014-07-15 Loma Linda University Substances, compositions and methods for preventing and treating immune-mediated inflammatory disorders
US20090191218A1 (en) 2005-05-11 2009-07-30 Fengchun Li DNA Vaccines And Methods For The Prevention Of Transplantation Rejection
WO2009114735A1 (en) * 2008-03-12 2009-09-17 Loma Linda University Dna vaccines and methods for the prevention of transplantation rejection
BRPI0619894B8 (pt) * 2005-12-15 2021-05-25 Mitsubishi Tanabe Pharma Corp composto de amina e composição farmacêutica
JP5722524B2 (ja) * 2006-03-02 2015-05-20 アレクシオン ファーマシューティカルズ, インコーポレイテッド 補体活性を抑制することによる同種移植片の生存の延長
EP2489729B1 (en) * 2006-09-28 2015-02-25 Loma Linda University Apoptotic cell-mediated transfection of mammalian cells with interfering RNA
TW200946105A (en) 2008-02-07 2009-11-16 Kyorin Seiyaku Kk Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient
PL2278960T5 (pl) 2008-03-17 2020-06-29 Actelion Pharmaceuticals Ltd. Schemat dawkowania dla selektywnego agonisty receptora sip1
JP2012508215A (ja) * 2008-11-11 2012-04-05 ノバルティス アーゲー 有機化合物
PT2356090T (pt) * 2008-11-11 2017-10-16 Novartis Ag Formas cristalinas de fingolimod, hcl
JP5654587B2 (ja) * 2009-06-30 2015-01-14 ライフスキャン・インコーポレイテッドLifescan,Inc. 基礎インスリン療法を算出する分析物試験方法及び装置
BRPI1015133A2 (pt) * 2009-06-30 2016-04-19 Lifescan Scotland Ltd sistemas para o gerenciamento de diabetes e métodos
BR112012007134A2 (pt) * 2009-09-29 2016-08-23 Lifescan Scotland Ltd dispositivo e método de teste de analito para controle de diabetes
US9563743B2 (en) * 2010-02-25 2017-02-07 Lifescan Scotland Limited Analyte testing method and system with high and low blood glucose trends notification
DK2758074T3 (da) 2011-09-23 2020-07-27 Univ Loma Linda Bakteriestammer der udtrykker methylasegener og anvendelser deraf
US11680273B2 (en) 2011-09-23 2023-06-20 Loma Linda University Treatment of autoimmune diseases
CN114306643A (zh) * 2021-11-30 2022-04-12 中国科学院昆明动物研究所 一种恒河猴免疫抑制模型的构建方法及在car-t细胞植活上的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69321823T2 (de) * 1992-10-21 1999-06-02 Taito Co., Ltd., Tokio/Tokyo 2-amino-1, 3- propandiolverbindung und immunosuppressium
US5679546A (en) * 1993-09-24 1997-10-21 Cytomed, Inc. Chimeric proteins which block complement activation
CA2184356A1 (en) * 1994-03-03 1995-09-08 Russell P. Rother Terminal complement inhibitor fusion genes and proteins
GB9624038D0 (en) * 1996-11-19 1997-01-08 Sandoz Ltd Organic compounds
JPH1180026A (ja) * 1997-09-02 1999-03-23 Yoshitomi Pharmaceut Ind Ltd 新規免疫抑制剤、その使用方法およびその同定方法
JP4318921B2 (ja) * 2001-02-22 2009-08-26 ノバルティス アクチエンゲゼルシャフト 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用

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