CA2445605A1 - Treatment or prophylaxis of insulin-producing cell graft rejection - Google Patents
Treatment or prophylaxis of insulin-producing cell graft rejection Download PDFInfo
- Publication number
- CA2445605A1 CA2445605A1 CA002445605A CA2445605A CA2445605A1 CA 2445605 A1 CA2445605 A1 CA 2445605A1 CA 002445605 A CA002445605 A CA 002445605A CA 2445605 A CA2445605 A CA 2445605A CA 2445605 A1 CA2445605 A1 CA 2445605A1
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- CA
- Canada
- Prior art keywords
- insulin
- antibody
- combination according
- receptor
- producing cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29706901P | 2001-06-08 | 2001-06-08 | |
| US60/297,069 | 2001-06-08 | ||
| PCT/EP2002/006278 WO2002100148A2 (en) | 2001-06-08 | 2002-06-07 | Treatment or prophylaxis of insulin-producing cell graft rejection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2445605A1 true CA2445605A1 (en) | 2002-12-19 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002445605A Abandoned CA2445605A1 (en) | 2001-06-08 | 2002-06-07 | Treatment or prophylaxis of insulin-producing cell graft rejection |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US20030003099A1 (https=) |
| EP (1) | EP1429845B1 (https=) |
| JP (1) | JP4476623B2 (https=) |
| CN (1) | CN1524002A (https=) |
| AT (1) | ATE424893T1 (https=) |
| AU (1) | AU2002320828B2 (https=) |
| BR (1) | BR0209319A (https=) |
| CA (1) | CA2445605A1 (https=) |
| DE (1) | DE60231522D1 (https=) |
| ES (1) | ES2322442T3 (https=) |
| IL (1) | IL158384A0 (https=) |
| NO (1) | NO20035434D0 (https=) |
| NZ (1) | NZ529044A (https=) |
| PL (1) | PL364359A1 (https=) |
| PT (1) | PT1429845E (https=) |
| RU (1) | RU2003136730A (https=) |
| WO (1) | WO2002100148A2 (https=) |
| ZA (1) | ZA200307893B (https=) |
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| ES2267993T3 (es) * | 2001-02-22 | 2007-03-16 | Novartis Ag | Uso de agentes de migracion acelerada de linfocitos para la fabricacion de un medicamento para el tratamiento de la funcion retardada del injerto. |
| ES2528362T3 (es) * | 2004-05-14 | 2015-02-09 | Alexion Pharmaceuticals, Inc. | Prolongación de la supervivencia de un aloinjerto por inhibición de la actividad del complemento |
| CN101014329B (zh) * | 2004-07-16 | 2010-09-08 | 杏林制药株式会社 | 用于对器官或组织的移植的排异反应或骨髓移植的移植物抗宿主反应预防或治疗的药物组合物 |
| KR20140095109A (ko) * | 2004-11-29 | 2014-07-31 | 노파르티스 아게 | Ｓ１ｐ 수용체 효능제의 투여 용법 |
| US20080206240A1 (en) * | 2005-02-08 | 2008-08-28 | Shreeram Aradhye | Antilymphocyte Antibody Induction |
| US20090191218A1 (en) | 2005-05-11 | 2009-07-30 | Fengchun Li | DNA Vaccines And Methods For The Prevention Of Transplantation Rejection |
| DE602006015373D1 (de) * | 2005-05-11 | 2010-08-19 | Univ Loma Linda | Zusammensetzungen und Verfahren zur Prävention und Behandlung von immunvermittelten Entzündungskrankheiten |
| KR101346527B1 (ko) * | 2005-12-15 | 2013-12-31 | 미쓰비시 타나베 파마 코퍼레이션 | 아민 화합물 및 그 의약 용도 |
| RS53864B1 (sr) * | 2006-03-02 | 2015-08-31 | Alexion Pharmaceuticals, Inc. | Produžavanje preživljavanja alografta inhibiranjem aktivnosti komplementa |
| EP2069375B1 (en) * | 2006-09-28 | 2012-03-28 | Loma Linda University | Apoptotic cell-mediated transfection of mammalian cells with interfering RNA |
| WO2009099174A1 (ja) | 2008-02-07 | 2009-08-13 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤 |
| EP3332801B1 (en) * | 2008-03-12 | 2023-09-13 | Loma Linda University | Dna vaccines and methods for the prevention of transplantation rejection |
| HUE033168T2 (en) | 2008-03-17 | 2017-11-28 | Actelion Pharmaceuticals Ltd | Dosage regimen for selective SIP1 receptor agonist |
| CA2743232C (en) * | 2008-11-11 | 2015-12-29 | Novartis Ag | Crystalline forms of fingolimod hcl |
| MX2011004924A (es) * | 2008-11-11 | 2011-05-30 | Novartis Ag | Sales de fingolimod. |
| EP2455876A3 (en) * | 2009-06-30 | 2013-01-30 | Lifescan Scotland Limited | System and method for diabetes management |
| JP5654587B2 (ja) * | 2009-06-30 | 2015-01-14 | ライフスキャン・インコーポレイテッドＬｉｆｅｓｃａｎ，Ｉｎｃ． | 基礎インスリン療法を算出する分析物試験方法及び装置 |
| ES2631610T3 (es) * | 2009-09-29 | 2017-09-01 | Lifescan Scotland Limited | Dispositivo y método de ensayo de analito para la gestión de la diabetes |
| WO2011106029A1 (en) * | 2010-02-25 | 2011-09-01 | Lifescan Scotland Limited | Analyte testing method and system with high and low blood glucose trends notification |
| US11680273B2 (en) | 2011-09-23 | 2023-06-20 | Loma Linda University | Treatment of autoimmune diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5604229A (en) * | 1992-10-21 | 1997-02-18 | Yoshitomi Pharmaceutical Industries, Ltd. | 2-amino-1,3-propanediol compound and immunosuppressant |
| US5679546A (en) * | 1993-09-24 | 1997-10-21 | Cytomed, Inc. | Chimeric proteins which block complement activation |
| WO1995023512A1 (en) * | 1994-03-03 | 1995-09-08 | Alexion Pharmaceuticals, Inc. | Terminal complement inhibitor fusion genes and proteins |
| GB9624038D0 (en) * | 1996-11-19 | 1997-01-08 | Sandoz Ltd | Organic compounds |
| JPH1180026A (ja) * | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
| ES2267993T3 (es) * | 2001-02-22 | 2007-03-16 | Novartis Ag | Uso de agentes de migracion acelerada de linfocitos para la fabricacion de un medicamento para el tratamiento de la funcion retardada del injerto. |
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- 2002-06-07 ES ES02754637T patent/ES2322442T3/es not_active Expired - Lifetime
- 2002-06-07 WO PCT/EP2002/006278 patent/WO2002100148A2/en not_active Ceased
- 2002-06-07 CA CA002445605A patent/CA2445605A1/en not_active Abandoned
- 2002-06-07 IL IL15838402A patent/IL158384A0/xx unknown
- 2002-06-07 PL PL02364359A patent/PL364359A1/xx not_active Application Discontinuation
- 2002-06-07 RU RU2003136730/15A patent/RU2003136730A/ru not_active Application Discontinuation
- 2002-06-07 PT PT02754637T patent/PT1429845E/pt unknown
- 2002-06-07 AT AT02754637T patent/ATE424893T1/de active
- 2002-06-07 AU AU2002320828A patent/AU2002320828B2/en not_active Ceased
- 2002-06-07 CN CNA028098498A patent/CN1524002A/zh active Pending
- 2002-06-07 DE DE60231522T patent/DE60231522D1/de not_active Expired - Lifetime
- 2002-06-07 NZ NZ529044A patent/NZ529044A/en unknown
- 2002-06-07 BR BR0209319-7A patent/BR0209319A/pt not_active IP Right Cessation
- 2002-06-07 US US10/164,755 patent/US20030003099A1/en not_active Abandoned
- 2002-06-07 EP EP02754637A patent/EP1429845B1/en not_active Expired - Lifetime
- 2002-06-07 JP JP2003502981A patent/JP4476623B2/ja not_active Expired - Fee Related
-
2003
- 2003-10-09 ZA ZA200307893A patent/ZA200307893B/en unknown
- 2003-12-05 NO NO20035434A patent/NO20035434D0/no not_active Application Discontinuation
-
2006
- 2006-03-09 US US11/372,383 patent/US20060153842A1/en not_active Abandoned
-
2008
- 2008-04-22 US US12/107,726 patent/US20080199465A1/en not_active Abandoned
-
2011
- 2011-06-06 US US13/154,106 patent/US20110236382A1/en not_active Abandoned
-
2013
- 2013-12-05 US US14/098,179 patent/US20140093502A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL364359A1 (en) | 2004-12-13 |
| US20060153842A1 (en) | 2006-07-13 |
| EP1429845A2 (en) | 2004-06-23 |
| NZ529044A (en) | 2008-03-28 |
| JP4476623B2 (ja) | 2010-06-09 |
| RU2003136730A (ru) | 2005-05-20 |
| US20080199465A1 (en) | 2008-08-21 |
| EP1429845B1 (en) | 2009-03-11 |
| DE60231522D1 (de) | 2009-04-23 |
| AU2002320828B2 (en) | 2006-02-02 |
| US20110236382A1 (en) | 2011-09-29 |
| US20140093502A1 (en) | 2014-04-03 |
| WO2002100148A3 (en) | 2004-04-22 |
| US20030003099A1 (en) | 2003-01-02 |
| IL158384A0 (en) | 2004-05-12 |
| WO2002100148A2 (en) | 2002-12-19 |
| ZA200307893B (en) | 2004-09-06 |
| CN1524002A (zh) | 2004-08-25 |
| ATE424893T1 (de) | 2009-03-15 |
| PT1429845E (pt) | 2009-06-15 |
| ES2322442T3 (es) | 2009-06-22 |
| BR0209319A (pt) | 2004-07-20 |
| NO20035434D0 (no) | 2003-12-05 |
| JP2004534788A (ja) | 2004-11-18 |
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