JP4476623B2 - インスリン産生細胞移植片拒絶の処置または予防 - Google Patents
インスリン産生細胞移植片拒絶の処置または予防 Download PDFInfo
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- JP4476623B2 JP4476623B2 JP2003502981A JP2003502981A JP4476623B2 JP 4476623 B2 JP4476623 B2 JP 4476623B2 JP 2003502981 A JP2003502981 A JP 2003502981A JP 2003502981 A JP2003502981 A JP 2003502981A JP 4476623 B2 JP4476623 B2 JP 4476623B2
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- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29706901P | 2001-06-08 | 2001-06-08 | |
| PCT/EP2002/006278 WO2002100148A2 (en) | 2001-06-08 | 2002-06-07 | Treatment or prophylaxis of insulin-producing cell graft rejection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004534788A JP2004534788A (ja) | 2004-11-18 |
| JP2004534788A5 JP2004534788A5 (https=) | 2005-12-22 |
| JP4476623B2 true JP4476623B2 (ja) | 2010-06-09 |
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| JP2003502981A Expired - Fee Related JP4476623B2 (ja) | 2001-06-08 | 2002-06-07 | インスリン産生細胞移植片拒絶の処置または予防 |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US20030003099A1 (https=) |
| EP (1) | EP1429845B1 (https=) |
| JP (1) | JP4476623B2 (https=) |
| CN (1) | CN1524002A (https=) |
| AT (1) | ATE424893T1 (https=) |
| AU (1) | AU2002320828B2 (https=) |
| BR (1) | BR0209319A (https=) |
| CA (1) | CA2445605A1 (https=) |
| DE (1) | DE60231522D1 (https=) |
| ES (1) | ES2322442T3 (https=) |
| IL (1) | IL158384A0 (https=) |
| NO (1) | NO20035434D0 (https=) |
| NZ (1) | NZ529044A (https=) |
| PL (1) | PL364359A1 (https=) |
| PT (1) | PT1429845E (https=) |
| RU (1) | RU2003136730A (https=) |
| WO (1) | WO2002100148A2 (https=) |
| ZA (1) | ZA200307893B (https=) |
Families Citing this family (22)
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| JP4318921B2 (ja) * | 2001-02-22 | 2009-08-26 | ノバルティス アクチエンゲゼルシャフト | 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用 |
| EP2338511A3 (en) * | 2004-05-14 | 2012-07-25 | Alexion Pharmaceuticals, Inc. | Prolongation of survival of an allograft by inhibiting complement activity |
| US7781617B2 (en) * | 2004-07-16 | 2010-08-24 | Kyorin Pharmaceutical Co., Ltd | Effective use method of medicaments and method of preventing expression of side effect |
| KR20070085465A (ko) * | 2004-11-29 | 2007-08-27 | 노파르티스 아게 | Ｓ１ｐ 수용체 효능제의 투여 용법 |
| CA2595960A1 (en) * | 2005-02-08 | 2006-08-17 | Novartis Ag | Antilymphocyte antibody induction by combination of an s1p receptor agonist/modulator and of immunosuppressive drugs |
| US8778327B2 (en) * | 2005-05-11 | 2014-07-15 | Loma Linda University | Substances, compositions and methods for preventing and treating immune-mediated inflammatory disorders |
| US20090191218A1 (en) | 2005-05-11 | 2009-07-30 | Fengchun Li | DNA Vaccines And Methods For The Prevention Of Transplantation Rejection |
| WO2009114735A1 (en) * | 2008-03-12 | 2009-09-17 | Loma Linda University | Dna vaccines and methods for the prevention of transplantation rejection |
| BRPI0619894B8 (pt) * | 2005-12-15 | 2021-05-25 | Mitsubishi Tanabe Pharma Corp | composto de amina e composição farmacêutica |
| JP5722524B2 (ja) * | 2006-03-02 | 2015-05-20 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 補体活性を抑制することによる同種移植片の生存の延長 |
| EP2489729B1 (en) * | 2006-09-28 | 2015-02-25 | Loma Linda University | Apoptotic cell-mediated transfection of mammalian cells with interfering RNA |
| TW200946105A (en) | 2008-02-07 | 2009-11-16 | Kyorin Seiyaku Kk | Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient |
| PL2278960T5 (pl) | 2008-03-17 | 2020-06-29 | Actelion Pharmaceuticals Ltd. | Schemat dawkowania dla selektywnego agonisty receptora sip1 |
| JP2012508215A (ja) * | 2008-11-11 | 2012-04-05 | ノバルティス アーゲー | 有機化合物 |
| PT2356090T (pt) * | 2008-11-11 | 2017-10-16 | Novartis Ag | Formas cristalinas de fingolimod, hcl |
| JP5654587B2 (ja) * | 2009-06-30 | 2015-01-14 | ライフスキャン・インコーポレイテッドＬｉｆｅｓｃａｎ，Ｉｎｃ． | 基礎インスリン療法を算出する分析物試験方法及び装置 |
| BRPI1015133A2 (pt) * | 2009-06-30 | 2016-04-19 | Lifescan Scotland Ltd | sistemas para o gerenciamento de diabetes e métodos |
| BR112012007134A2 (pt) * | 2009-09-29 | 2016-08-23 | Lifescan Scotland Ltd | dispositivo e método de teste de analito para controle de diabetes |
| US9563743B2 (en) * | 2010-02-25 | 2017-02-07 | Lifescan Scotland Limited | Analyte testing method and system with high and low blood glucose trends notification |
| DK2758074T3 (da) | 2011-09-23 | 2020-07-27 | Univ Loma Linda | Bakteriestammer der udtrykker methylasegener og anvendelser deraf |
| US11680273B2 (en) | 2011-09-23 | 2023-06-20 | Loma Linda University | Treatment of autoimmune diseases |
| CN114306643A (zh) * | 2021-11-30 | 2022-04-12 | 中国科学院昆明动物研究所 | 一种恒河猴免疫抑制模型的构建方法及在car-t细胞植活上的应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69321823T2 (de) * | 1992-10-21 | 1999-06-02 | Taito Co., Ltd., Tokio/Tokyo | 2-amino-1, 3- propandiolverbindung und immunosuppressium |
| US5679546A (en) * | 1993-09-24 | 1997-10-21 | Cytomed, Inc. | Chimeric proteins which block complement activation |
| CA2184356A1 (en) * | 1994-03-03 | 1995-09-08 | Russell P. Rother | Terminal complement inhibitor fusion genes and proteins |
| GB9624038D0 (en) * | 1996-11-19 | 1997-01-08 | Sandoz Ltd | Organic compounds |
| JPH1180026A (ja) * | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
| JP4318921B2 (ja) * | 2001-02-22 | 2009-08-26 | ノバルティス アクチエンゲゼルシャフト | 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用 |
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Also Published As
| Publication number | Publication date |
|---|---|
| PL364359A1 (en) | 2004-12-13 |
| EP1429845A2 (en) | 2004-06-23 |
| WO2002100148A3 (en) | 2004-04-22 |
| DE60231522D1 (de) | 2009-04-23 |
| WO2002100148A2 (en) | 2002-12-19 |
| US20030003099A1 (en) | 2003-01-02 |
| PT1429845E (pt) | 2009-06-15 |
| US20080199465A1 (en) | 2008-08-21 |
| CA2445605A1 (en) | 2002-12-19 |
| ES2322442T3 (es) | 2009-06-22 |
| NZ529044A (en) | 2008-03-28 |
| US20060153842A1 (en) | 2006-07-13 |
| EP1429845B1 (en) | 2009-03-11 |
| IL158384A0 (en) | 2004-05-12 |
| RU2003136730A (ru) | 2005-05-20 |
| NO20035434D0 (no) | 2003-12-05 |
| US20110236382A1 (en) | 2011-09-29 |
| ATE424893T1 (de) | 2009-03-15 |
| JP2004534788A (ja) | 2004-11-18 |
| AU2002320828B2 (en) | 2006-02-02 |
| ZA200307893B (en) | 2004-09-06 |
| BR0209319A (pt) | 2004-07-20 |
| US20140093502A1 (en) | 2014-04-03 |
| CN1524002A (zh) | 2004-08-25 |
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