JP2004521097A - 有機化合物 - Google Patents

有機化合物 Download PDF

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Publication number
JP2004521097A
JP2004521097A JP2002550981A JP2002550981A JP2004521097A JP 2004521097 A JP2004521097 A JP 2004521097A JP 2002550981 A JP2002550981 A JP 2002550981A JP 2002550981 A JP2002550981 A JP 2002550981A JP 2004521097 A JP2004521097 A JP 2004521097A
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JP
Japan
Prior art keywords
halogen
alkyl
substituted
hydrogen
formula
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2002550981A
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English (en)
Japanese (ja)
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JP2004521097A5 (enExample
Inventor
ドユクレイ，ピエール
ブービエ，ジヤツク
Original Assignee
ノバルティス アクチエンゲゼルシャフト
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Application filed by ノバルティス アクチエンゲゼルシャフト filed Critical ノバルティス アクチエンゲゼルシャフト
Publication of JP2004521097A publication Critical patent/JP2004521097A/ja
Publication of JP2004521097A5 publication Critical patent/JP2004521097A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Paper (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2002550981A 2000-12-20 2001-12-18 有機化合物 Pending JP2004521097A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH24892000 2000-12-20
PCT/EP2001/014926 WO2002049641A2 (en) 2000-12-20 2001-12-18 Anti-endoparasitic amidoacetonitrils

Publications (2)

Publication Number Publication Date
JP2004521097A true JP2004521097A (ja) 2004-07-15
JP2004521097A5 JP2004521097A5 (enExample) 2005-05-26

Family

ID=4569596

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002550981A Pending JP2004521097A (ja) 2000-12-20 2001-12-18 有機化合物

Country Status (21)

Country Link
US (1) US7700656B2 (enExample)
EP (1) EP1392281B1 (enExample)
JP (1) JP2004521097A (enExample)
KR (1) KR100850252B1 (enExample)
CN (1) CN1531426A (enExample)
AR (1) AR035523A1 (enExample)
AT (1) ATE354360T1 (enExample)
AU (2) AU2002234588B2 (enExample)
BR (1) BR0116326A (enExample)
CA (1) CA2432388C (enExample)
CY (1) CY1106509T1 (enExample)
DE (1) DE60126838T2 (enExample)
DK (1) DK1392281T3 (enExample)
ES (1) ES2281453T3 (enExample)
MX (1) MXPA03005701A (enExample)
NZ (1) NZ526538A (enExample)
PT (1) PT1392281E (enExample)
RU (1) RU2286775C2 (enExample)
TW (1) TWI292712B (enExample)
WO (1) WO2002049641A2 (enExample)
ZA (1) ZA200304331B (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006043654A1 (ja) * 2004-10-22 2006-04-27 Nihon Nohyaku Co., Ltd. アセトニトリル誘導体及び有害生物防除剤並びにその使用方法
JP2008501761A (ja) * 2004-06-10 2008-01-24 ノバルティス アクチエンゲゼルシャフト アミノアセトニトリル誘導体及び温血動物上の寄生虫を駆除するためのこれらの使用
JP2008518997A (ja) * 2004-11-09 2008-06-05 ノバルティス アクチエンゲゼルシャフト アミドアセトニトリル化合物のラセミ体からのアミドアセトニトリル化合物の鏡像異性体の調製方法
JP2010518067A (ja) * 2007-02-09 2010-05-27 ファイザー・リミテッド 抗寄生虫剤
JP2010519249A (ja) * 2007-02-21 2010-06-03 ファイザー・リミテッド ベンゾフラン抗寄生虫剤
JP2012506441A (ja) * 2008-10-21 2012-03-15 メリアル リミテッド チオアミド化合物、その製造方法及び使用方法
JP2016094448A (ja) * 2012-02-14 2016-05-26 日本曹達株式会社 アリールオキシ酢酸アミド化合物および有害生物防除剤
JP2016523280A (ja) * 2013-07-01 2016-08-08 ウニヴェルズィテート チューリッヒ ２−シアノ−２−アミノベンゾエート−プロピル有機金属誘導体及びそれらの駆虫薬としての用途
JP2016531841A (ja) * 2013-09-13 2016-10-13 日本農薬株式会社 アミノアセトニトリル化合物を有効成分として含有する抗癌剤
JP2018513835A (ja) * 2015-02-24 2018-05-31 ピットニー ファーマシューティカル ピーティーワイ リミテッド アミノアセトニトリル化合物を有効成分とする抗癌剤

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR035531A1 (es) * 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
AR036054A1 (es) * 2001-06-15 2004-08-04 Novartis Ag Uso de compuestos de aminoacetonitrilo para el control de plagas, una composicion y un proceso para dicho control y una composicion farmaceutica contra parasitos
WO2003004474A1 (en) * 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
AR037746A1 (es) * 2001-12-06 2004-12-01 Novartis Ag Compuestos derivados de amidoacetonitrilo, un procedimiento para su preparacion, un procedimiento para la preparacion de compuestos intermediarios, una composicion para combatir parasitos, un procedimiento para combatir dichos parasitos, y el empleo de dichos derivados para la preparacion de una com
AR039020A1 (es) * 2002-03-21 2005-02-02 Novartis Ag Compuestos de aminoacetonitrilo
TW200400932A (en) * 2002-06-19 2004-01-16 Novartis Ag Organic compounds
AR042420A1 (es) 2002-09-11 2005-06-22 Novartis Ag Benzotriazolil- aminoacetonitril compuestos, proceso para su preparacion, metodo y uso de los mismos en el control de endo- y ecto-parasitos dentro y sobre ganado productor de sangre caliente y animales domesticos y plantas, y en la preparacion de una composicion farmaceutica
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
EP1910278A1 (en) * 2005-07-25 2008-04-16 Novartis AG Amidonitrile compounds
DE102006025874A1 (de) 2006-06-02 2007-12-06 Bayer Cropscience Ag Alkoxyalkyl-substituierte cyclische Ketoenole
WO2008062005A1 (en) * 2006-11-24 2008-05-29 Novartis Ag The use of aminoacetonitril compounds in the control of endoparasites in warm- blood animals.
KR101472649B1 (ko) 2007-05-15 2014-12-16 메리얼 리미티드 아릴로아졸-2-일 시아노에틸아미노 화합물, 이의 제조방법 및 이의 사용방법
RS58508B1 (sr) 2008-11-14 2019-04-30 Merial Inc Enantiomerno obogaćena paraziticidalna jedinjenja ariloazol-2-il cijanoetilamino
UY33282A (es) * 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
ES2625990T3 (es) * 2011-03-02 2017-07-21 The University Of Tokyo Agente de control de endoparásitos
AR088984A1 (es) * 2011-11-25 2014-07-23 Bayer Ip Gmbh Aril y/o heteroaril carboxamidas utiles como endoparasiticidas en animales o seres humanos
US9790176B2 (en) 2012-08-06 2017-10-17 Pitney Pharmaceuticals Pty Limited Compounds for the treatment of mTOR pathway related diseases
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
EP3235815A1 (de) 2016-04-19 2017-10-25 Philipps-Universität Marburg Wirkstoffe gegen parasitäre helminthen

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1520925A (fr) * 1966-04-22 1968-04-12 Abbott Lab Nouveaux benzoylamino-nitriles
US3457294A (en) * 1966-04-22 1969-07-22 Abbott Lab N-(substituted-benzoyl) aminoaceto- and aminopropionitriles
US4515731A (en) * 1975-08-25 1985-05-07 Monsanto Company Asymmetric catalysis
GB8517279D0 (en) * 1985-07-08 1985-08-14 Ici Plc Benzamide derivatives
JP2994182B2 (ja) * 1992-07-23 1999-12-27 石原産業株式会社 アミド系化合物又はその塩、それらの製造方法及びそれらを含有する有害動物防除剤
US6239077B1 (en) * 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
AR035531A1 (es) * 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
EP1390344B1 (en) * 2001-05-15 2006-12-27 Novartis AG Benzamidoacetonitrile derivatives and their use as antiparasitics
AR036054A1 (es) * 2001-06-15 2004-08-04 Novartis Ag Uso de compuestos de aminoacetonitrilo para el control de plagas, una composicion y un proceso para dicho control y una composicion farmaceutica contra parasitos
WO2003004474A1 (en) * 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
AR038156A1 (es) * 2002-01-21 2004-12-29 Novartis Ag Compuestos de amidoacetonitrilo, proceso para su preparacion, composicion para controlar los parasitos, y uso de estos compuestos para preparar una composicion farmaceutica

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008501761A (ja) * 2004-06-10 2008-01-24 ノバルティス アクチエンゲゼルシャフト アミノアセトニトリル誘導体及び温血動物上の寄生虫を駆除するためのこれらの使用
WO2006043654A1 (ja) * 2004-10-22 2006-04-27 Nihon Nohyaku Co., Ltd. アセトニトリル誘導体及び有害生物防除剤並びにその使用方法
JP2008518997A (ja) * 2004-11-09 2008-06-05 ノバルティス アクチエンゲゼルシャフト アミドアセトニトリル化合物のラセミ体からのアミドアセトニトリル化合物の鏡像異性体の調製方法
JP2010518067A (ja) * 2007-02-09 2010-05-27 ファイザー・リミテッド 抗寄生虫剤
JP2010519249A (ja) * 2007-02-21 2010-06-03 ファイザー・リミテッド ベンゾフラン抗寄生虫剤
JP2012506441A (ja) * 2008-10-21 2012-03-15 メリアル リミテッド チオアミド化合物、その製造方法及び使用方法
JP2016094448A (ja) * 2012-02-14 2016-05-26 日本曹達株式会社 アリールオキシ酢酸アミド化合物および有害生物防除剤
JP2016523280A (ja) * 2013-07-01 2016-08-08 ウニヴェルズィテート チューリッヒ ２−シアノ−２−アミノベンゾエート−プロピル有機金属誘導体及びそれらの駆虫薬としての用途
JP2016531841A (ja) * 2013-09-13 2016-10-13 日本農薬株式会社 アミノアセトニトリル化合物を有効成分として含有する抗癌剤
AU2014319290B2 (en) * 2013-09-13 2019-07-18 Pitney Pharmaceuticals Pty Limited Anticancer agent comprising aminoacetonitrile compound as active ingredient
JP2018513835A (ja) * 2015-02-24 2018-05-31 ピットニー ファーマシューティカル ピーティーワイ リミテッド アミノアセトニトリル化合物を有効成分とする抗癌剤

Also Published As

Publication number Publication date
DE60126838T2 (de) 2007-11-08
US7700656B2 (en) 2010-04-20
US20040082624A1 (en) 2004-04-29
ATE354360T1 (de) 2007-03-15
CY1106509T1 (el) 2012-01-25
DK1392281T3 (da) 2007-06-11
WO2002049641A2 (en) 2002-06-27
MXPA03005701A (es) 2003-10-06
PT1392281E (pt) 2007-05-31
DE60126838D1 (de) 2007-04-05
AU2002234588B2 (en) 2005-03-24
BR0116326A (pt) 2004-07-06
AU3458802A (en) 2002-07-01
CN1531426A (zh) 2004-09-22
CA2432388A1 (en) 2002-06-27
CA2432388C (en) 2010-06-08
EP1392281A2 (en) 2004-03-03
TWI292712B (en) 2008-01-21
RU2003122196A (ru) 2005-03-20
KR20030061414A (ko) 2003-07-18
KR100850252B1 (ko) 2008-08-04
ZA200304331B (en) 2004-04-28
ES2281453T3 (es) 2007-10-01
WO2002049641A3 (en) 2003-12-04
NZ526538A (en) 2005-12-23
AR035523A1 (es) 2004-06-02
EP1392281B1 (en) 2007-02-21
RU2286775C2 (ru) 2006-11-10

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