JP2004520290A5 - - Google Patents

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Publication number
JP2004520290A5
JP2004520290A5 JP2002546515A JP2002546515A JP2004520290A5 JP 2004520290 A5 JP2004520290 A5 JP 2004520290A5 JP 2002546515 A JP2002546515 A JP 2002546515A JP 2002546515 A JP2002546515 A JP 2002546515A JP 2004520290 A5 JP2004520290 A5 JP 2004520290A5
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JP
Japan
Prior art keywords
compound
pharmaceutically acceptable
acceptable salt
condition
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2002546515A
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English (en)
Japanese (ja)
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JP4177101B2 (ja
JP2004520290A (ja
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Publication date
Priority claimed from SE0004458A external-priority patent/SE0004458D0/xx
Priority claimed from SE0100965A external-priority patent/SE0100965D0/xx
Priority claimed from SE0101239A external-priority patent/SE0101239D0/xx
Priority claimed from SE0102921A external-priority patent/SE0102921D0/xx
Application filed filed Critical
Priority claimed from PCT/SE2001/002657 external-priority patent/WO2002044145A1/en
Publication of JP2004520290A publication Critical patent/JP2004520290A/ja
Publication of JP2004520290A5 publication Critical patent/JP2004520290A5/ja
Application granted granted Critical
Publication of JP4177101B2 publication Critical patent/JP4177101B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002546515A 2000-12-01 2001-11-30 新規マンデル酸誘導体とそれらのトロンビン阻害剤としての使用 Expired - Fee Related JP4177101B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE0004458A SE0004458D0 (sv) 2000-12-01 2000-12-01 Pharmaceutically useful compounds
SE0100965A SE0100965D0 (sv) 2001-03-19 2001-03-19 Pharmaceutically-useful compounds
SE0101239A SE0101239D0 (sv) 2001-04-06 2001-04-06 Pharmaceutically useful compounds
SE0102921A SE0102921D0 (sv) 2001-08-30 2001-08-30 Pharmaceutically useful compounds
PCT/SE2001/002657 WO2002044145A1 (en) 2000-12-01 2001-11-30 New mandelic acid derivatives and their use as throbin inhibitors

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2008006608A Division JP2008156362A (ja) 2000-12-01 2008-01-16 新規マンデル酸誘導体とそれらのトロンビン阻害剤としての使用
JP2008006611A Division JP2008138009A (ja) 2000-12-01 2008-01-16 新規マンデル酸誘導体とそれらのトロンビン阻害剤としての使用

Publications (3)

Publication Number Publication Date
JP2004520290A JP2004520290A (ja) 2004-07-08
JP2004520290A5 true JP2004520290A5 (https=) 2008-03-06
JP4177101B2 JP4177101B2 (ja) 2008-11-05

Family

ID=27484527

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2002546515A Expired - Fee Related JP4177101B2 (ja) 2000-12-01 2001-11-30 新規マンデル酸誘導体とそれらのトロンビン阻害剤としての使用
JP2008006611A Pending JP2008138009A (ja) 2000-12-01 2008-01-16 新規マンデル酸誘導体とそれらのトロンビン阻害剤としての使用
JP2008006608A Pending JP2008156362A (ja) 2000-12-01 2008-01-16 新規マンデル酸誘導体とそれらのトロンビン阻害剤としての使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2008006611A Pending JP2008138009A (ja) 2000-12-01 2008-01-16 新規マンデル酸誘導体とそれらのトロンビン阻害剤としての使用
JP2008006608A Pending JP2008156362A (ja) 2000-12-01 2008-01-16 新規マンデル酸誘導体とそれらのトロンビン阻害剤としての使用

Country Status (29)

Country Link
US (4) US20070218136A1 (https=)
EP (2) EP1347955B1 (https=)
JP (3) JP4177101B2 (https=)
KR (4) KR100914537B1 (https=)
CN (1) CN1291975C (https=)
AR (2) AR035216A1 (https=)
AT (1) ATE461171T1 (https=)
AU (2) AU2007203509A1 (https=)
BG (1) BG66261B1 (https=)
BR (1) BR0115861A (https=)
CA (1) CA2436220C (https=)
CY (1) CY1113487T1 (https=)
CZ (1) CZ303708B6 (https=)
DE (1) DE60141603D1 (https=)
DK (1) DK1347955T3 (https=)
EE (1) EE05382B1 (https=)
ES (1) ES2341318T3 (https=)
HU (1) HU228814B1 (https=)
IL (1) IL156096A0 (https=)
IS (1) IS2755B (https=)
MX (1) MXPA03004794A (https=)
MY (1) MY136133A (https=)
NO (3) NO325228B1 (https=)
NZ (1) NZ526205A (https=)
PL (1) PL207045B1 (https=)
PT (1) PT1347955E (https=)
SI (1) SI1347955T1 (https=)
SK (1) SK287692B6 (https=)
WO (1) WO2002044145A1 (https=)

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TW201319068A (zh) 2011-08-05 2013-05-16 必治妥美雅史谷比公司 作為ｘｉａ因子抑制劑之環狀ｐ１接合劑
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JP6033319B2 (ja) 2011-10-14 2016-11-30 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 第ＸＩａ因子阻害剤としての置換テトラヒドロイソキノリン化合物
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NO2760821T3 (https=) 2014-01-31 2018-03-10
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NO2721243T3 (https=) 2014-10-01 2018-10-20
ES2762987T3 (es) 2015-06-19 2020-05-26 Bristol Myers Squibb Co Macrociclos de diamida como inhibidores del factor XIA
CN114874222B (zh) 2015-07-29 2025-06-06 百时美施贵宝公司 携带非芳族p2,基团的因子xia新大环
KR102697816B1 (ko) 2015-08-05 2024-08-21 브리스톨-마이어스 스큅 컴퍼니 신규 치환된 글리신 유도된 fxia 억제제
CN105294520A (zh) * 2015-11-23 2016-02-03 大连九信生物化工科技有限公司 一种2-（2’,2’-二氟乙氧基）-6-三氟甲基苯基丙基硫醚的合成工艺
KR20180117156A (ko) 2016-03-02 2018-10-26 브리스톨-마이어스 스큅 컴퍼니 인자 XIa 억제 활성을 갖는 디아미드 마크로사이클
CN106674085B (zh) * 2016-12-20 2020-06-23 苏州汉德创宏生化科技有限公司 N-1,3-二氟异丙基-4-氨基哌啶类化合物的合成方法
JP2022509019A (ja) 2018-11-05 2022-01-20 シンジェンタ パーティシペーションズ アーゲー 殺有害生物的に活性なアゾール－アミド化合物
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