NO20050569L - Fremgangsmate for behandling av alvorlig hjertesvikt og medikament for dette - Google Patents
Fremgangsmate for behandling av alvorlig hjertesvikt og medikament for detteInfo
- Publication number
- NO20050569L NO20050569L NO20050569A NO20050569A NO20050569L NO 20050569 L NO20050569 L NO 20050569L NO 20050569 A NO20050569 A NO 20050569A NO 20050569 A NO20050569 A NO 20050569A NO 20050569 L NO20050569 L NO 20050569L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- heart failure
- severe heart
- drug
- procedure
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Sammendrag Fremgangsmåte for behandling av alvorlig hjertesvikt, som omfatter å administrere til en pasient en effektiv mengde av en benzazepinforbindelse (1): hvor R1 er H eller halogen, R2 er OH eller -NR5R6 (R5 og R6 er H eller lavere alkyl), R3 er H, halogen, lavere alkyl eller lavere alkoksy, R4 er halogen, lavere alkyl eller lavere alkoksy, eller et salt derav, og et farmasøytisk preparat som inneholder benzazepinforbindelsen (1) eller et salt derav, og anvendelse av forbindelsen (1) eller et salt derav til fremstilling av et medikament for behandling av alvorlig hjertesvikt.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44887803P | 2003-02-24 | 2003-02-24 | |
PCT/JP2004/002085 WO2004073716A1 (en) | 2003-02-24 | 2004-02-23 | Method for treating severe heart failure and medicament therefor |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20050569D0 NO20050569D0 (no) | 2005-02-02 |
NO20050569L true NO20050569L (no) | 2005-11-22 |
NO335369B1 NO335369B1 (no) | 2014-12-01 |
Family
ID=32908667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20050569A NO335369B1 (no) | 2003-02-24 | 2005-02-02 | Anvendelse av en bestemt benzazepin-forbindelse eller et farmasøytisk akseptabelt salt derav for fremstilling av et medikament egnet for behandling av alvorlig hjertesvikt, og medikament derav |
Country Status (24)
Country | Link |
---|---|
US (2) | US7423032B2 (no) |
EP (2) | EP1596868B1 (no) |
JP (2) | JP4771937B2 (no) |
KR (1) | KR100706727B1 (no) |
CN (1) | CN100577171C (no) |
AR (1) | AR043259A1 (no) |
AT (1) | ATE411803T1 (no) |
AU (2) | AU2004212842B9 (no) |
BR (1) | BRPI0405657A (no) |
CA (1) | CA2493475A1 (no) |
CY (1) | CY1108583T1 (no) |
DE (1) | DE602004017283D1 (no) |
DK (1) | DK1596868T3 (no) |
ES (1) | ES2315640T3 (no) |
HK (1) | HK1084037A1 (no) |
MX (1) | MXPA05001623A (no) |
MY (1) | MY143740A (no) |
NO (1) | NO335369B1 (no) |
PL (2) | PL218069B1 (no) |
PT (1) | PT1596868E (no) |
RU (2) | RU2346689C2 (no) |
SI (1) | SI1596868T1 (no) |
TW (1) | TWI322689B (no) |
WO (1) | WO2004073716A1 (no) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7468390B2 (en) * | 2002-01-17 | 2008-12-23 | Novartis Ag | Methods of treatment and pharmaceutical composition |
TWI322689B (en) * | 2003-02-24 | 2010-04-01 | Otsuka Pharma Co Ltd | Method for treating severe heart failure and medicament therefor |
DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
PL1968990T3 (pl) | 2005-12-27 | 2015-06-30 | Otsuka Pharma Co Ltd | Rozpuszczalny w wodzie związek benzoazepinowy i jego kompozycja farmaceutyczna |
JP5076327B2 (ja) * | 2006-02-01 | 2012-11-21 | 味の素株式会社 | 分岐鎖アミノ酸の心不全適応 |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
NZ581126A (en) * | 2007-05-15 | 2012-04-27 | Otsuka Pharma Co Ltd | Methods for using vasopressin antagonists with anthracycline chemotherapy agents to reduce cardiotoxicity and/or improve survival |
TWI405574B (zh) * | 2007-06-21 | 2013-08-21 | Otsuka Pharma Co Ltd | 藥學固體製劑及其製造方法 |
WO2011104269A1 (en) | 2008-02-26 | 2011-09-01 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
WO2011147849A1 (en) | 2010-05-25 | 2011-12-01 | Jenavalve Technology Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
JP5477413B2 (ja) * | 2012-04-24 | 2014-04-23 | 味の素株式会社 | 分岐鎖アミノ酸の心不全適応 |
JP6563394B2 (ja) | 2013-08-30 | 2019-08-21 | イェーナヴァルヴ テクノロジー インコーポレイテッド | 人工弁のための径方向に折り畳み自在のフレーム及び当該フレームを製造するための方法 |
WO2016177562A1 (en) | 2015-05-01 | 2016-11-10 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
EP4183371A1 (en) | 2016-05-13 | 2023-05-24 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
WO2018138658A1 (en) | 2017-01-27 | 2018-08-02 | Jenavalve Technology, Inc. | Heart valve mimicry |
CN110174474B (zh) * | 2019-05-24 | 2022-02-18 | 石家庄四药有限公司 | 复方电解质注射液(ⅱ)中l-苹果酸异构体的检测方法 |
CN112121051B (zh) * | 2020-09-30 | 2021-06-18 | 郑州大学 | 莫扎伐坦在制备抗消化道肿瘤药物中的应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5753677A (en) * | 1989-10-20 | 1998-05-19 | Otsuka Pharmaceutical Co., Ltd. | Benzoheterocyclic compounds |
DE69026708T2 (de) | 1989-10-20 | 1997-04-03 | Otsuka Pharma Co Ltd | Benzoheterozyklische verbindungen |
US5258510A (en) | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
TW249201B (no) | 1992-07-02 | 1995-06-11 | Otsuka Pharma Co Ltd | |
JPH0680641A (ja) | 1992-09-01 | 1994-03-22 | Otsuka Pharmaceut Co Ltd | 光学活性な5−ヒドロキシベンゾアゼピン誘導体の製造法 |
TW354762B (en) | 1993-02-23 | 1999-03-21 | Otsuka Pharma Co Ltd | Agent for prophylaxis or treatment of cataract |
JP2694319B2 (ja) | 1993-12-24 | 1997-12-24 | 大塚製薬株式会社 | 抗潰瘍剤 |
JP3002766B2 (ja) * | 1994-12-09 | 2000-01-24 | 大塚製薬株式会社 | 脳浮腫治療剤 |
JPH10120592A (ja) | 1996-10-22 | 1998-05-12 | Otsuka Pharmaceut Co Ltd | メニエール病乃至メニエール症候群治療剤 |
JP4210355B2 (ja) * | 1997-07-03 | 2009-01-14 | 大塚製薬株式会社 | 固形製剤組成物 |
ES2272341T3 (es) | 2000-01-26 | 2007-05-01 | Astellas Pharma Inc. | Combinaciones de inhibidores de enzima y de antagonistas. |
US20030103983A1 (en) * | 2002-05-09 | 2003-06-05 | Pressler Milton Lethan | Ace inhibitor-vasopressin antagonist combinations |
US20030008860A1 (en) * | 2002-05-09 | 2003-01-09 | Bakker-Arkema Rebecca Guggemos | Treatment of congestive heart failure |
ES2288899T3 (es) * | 2000-10-04 | 2008-02-01 | Astellas Pharma Inc. | Uso de un antagonista de vasopresina tal como conivaptan en la fabricacion de un medicamento para el tratamiento de la hipertension pulmonar. |
TWI322689B (en) * | 2003-02-24 | 2010-04-01 | Otsuka Pharma Co Ltd | Method for treating severe heart failure and medicament therefor |
-
2004
- 2004-02-05 TW TW093102582A patent/TWI322689B/zh not_active IP Right Cessation
- 2004-02-17 MY MYPI20040510A patent/MY143740A/en unknown
- 2004-02-23 RU RU2005102110/14A patent/RU2346689C2/ru active
- 2004-02-23 SI SI200430894T patent/SI1596868T1/sl unknown
- 2004-02-23 JP JP2006502681A patent/JP4771937B2/ja not_active Expired - Lifetime
- 2004-02-23 PL PL373432A patent/PL218069B1/pl unknown
- 2004-02-23 CA CA002493475A patent/CA2493475A1/en not_active Abandoned
- 2004-02-23 WO PCT/JP2004/002085 patent/WO2004073716A1/en active Application Filing
- 2004-02-23 EP EP04713672A patent/EP1596868B1/en not_active Expired - Lifetime
- 2004-02-23 CN CN200480000735A patent/CN100577171C/zh not_active Expired - Lifetime
- 2004-02-23 ES ES04713672T patent/ES2315640T3/es not_active Expired - Lifetime
- 2004-02-23 PL PL404315A patent/PL404315A1/pl unknown
- 2004-02-23 AR ARP040100557A patent/AR043259A1/es unknown
- 2004-02-23 KR KR1020057002579A patent/KR100706727B1/ko active IP Right Grant
- 2004-02-23 DE DE602004017283T patent/DE602004017283D1/de not_active Expired - Lifetime
- 2004-02-23 DK DK04713672T patent/DK1596868T3/da active
- 2004-02-23 AU AU2004212842A patent/AU2004212842B9/en not_active Expired
- 2004-02-23 BR BR0405657-4A patent/BRPI0405657A/pt not_active Application Discontinuation
- 2004-02-23 US US10/523,020 patent/US7423032B2/en active Active
- 2004-02-23 AT AT04713672T patent/ATE411803T1/de active
- 2004-02-23 MX MXPA05001623A patent/MXPA05001623A/es active IP Right Grant
- 2004-02-23 PT PT04713672T patent/PT1596868E/pt unknown
- 2004-02-23 EP EP08162362A patent/EP2000142A1/en not_active Withdrawn
-
2005
- 2005-02-02 NO NO20050569A patent/NO335369B1/no unknown
-
2006
- 2006-04-12 HK HK06104485.8A patent/HK1084037A1/xx not_active IP Right Cessation
-
2008
- 2008-05-05 US US12/149,578 patent/US7749993B2/en not_active Expired - Lifetime
- 2008-08-15 RU RU2008133654/14A patent/RU2008133654A/ru not_active Application Discontinuation
- 2008-11-20 CY CY20081101341T patent/CY1108583T1/el unknown
-
2009
- 2009-03-19 AU AU2009201109A patent/AU2009201109A1/en not_active Abandoned
-
2011
- 2011-03-07 JP JP2011049403A patent/JP2011148806A/ja active Pending
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