NO20050569L - Fremgangsmate for behandling av alvorlig hjertesvikt og medikament for dette - Google Patents

Fremgangsmate for behandling av alvorlig hjertesvikt og medikament for dette

Info

Publication number
NO20050569L
NO20050569L NO20050569A NO20050569A NO20050569L NO 20050569 L NO20050569 L NO 20050569L NO 20050569 A NO20050569 A NO 20050569A NO 20050569 A NO20050569 A NO 20050569A NO 20050569 L NO20050569 L NO 20050569L
Authority
NO
Norway
Prior art keywords
treatment
heart failure
severe heart
drug
procedure
Prior art date
Application number
NO20050569A
Other languages
English (en)
Other versions
NO20050569D0 (no
NO335369B1 (no
Inventor
Atsushi Ozaki
Yosuke Maki
Osamu Sato
Yoshitaka Yamamura
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32908667&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20050569(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO20050569D0 publication Critical patent/NO20050569D0/no
Publication of NO20050569L publication Critical patent/NO20050569L/no
Publication of NO335369B1 publication Critical patent/NO335369B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Sammendrag Fremgangsmåte for behandling av alvorlig hjertesvikt, som omfatter å administrere til en pasient en effektiv mengde av en benzazepinforbindelse (1): hvor R1 er H eller halogen, R2 er OH eller -NR5R6 (R5 og R6 er H eller lavere alkyl), R3 er H, halogen, lavere alkyl eller lavere alkoksy, R4 er halogen, lavere alkyl eller lavere alkoksy, eller et salt derav, og et farmasøytisk preparat som inneholder benzazepinforbindelsen (1) eller et salt derav, og anvendelse av forbindelsen (1) eller et salt derav til fremstilling av et medikament for behandling av alvorlig hjertesvikt.
NO20050569A 2003-02-24 2005-02-02 Anvendelse av en bestemt benzazepin-forbindelse eller et farmasøytisk akseptabelt salt derav for fremstilling av et medikament egnet for behandling av alvorlig hjertesvikt, og medikament derav NO335369B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44887803P 2003-02-24 2003-02-24
PCT/JP2004/002085 WO2004073716A1 (en) 2003-02-24 2004-02-23 Method for treating severe heart failure and medicament therefor

Publications (3)

Publication Number Publication Date
NO20050569D0 NO20050569D0 (no) 2005-02-02
NO20050569L true NO20050569L (no) 2005-11-22
NO335369B1 NO335369B1 (no) 2014-12-01

Family

ID=32908667

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050569A NO335369B1 (no) 2003-02-24 2005-02-02 Anvendelse av en bestemt benzazepin-forbindelse eller et farmasøytisk akseptabelt salt derav for fremstilling av et medikament egnet for behandling av alvorlig hjertesvikt, og medikament derav

Country Status (24)

Country Link
US (2) US7423032B2 (no)
EP (2) EP2000142A1 (no)
JP (2) JP4771937B2 (no)
KR (1) KR100706727B1 (no)
CN (1) CN100577171C (no)
AR (1) AR043259A1 (no)
AT (1) ATE411803T1 (no)
AU (2) AU2004212842B9 (no)
BR (1) BRPI0405657A (no)
CA (1) CA2493475A1 (no)
CY (1) CY1108583T1 (no)
DE (1) DE602004017283D1 (no)
DK (1) DK1596868T3 (no)
ES (1) ES2315640T3 (no)
HK (1) HK1084037A1 (no)
MX (1) MXPA05001623A (no)
MY (1) MY143740A (no)
NO (1) NO335369B1 (no)
PL (2) PL404315A1 (no)
PT (1) PT1596868E (no)
RU (2) RU2346689C2 (no)
SI (1) SI1596868T1 (no)
TW (1) TWI322689B (no)
WO (1) WO2004073716A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7468390B2 (en) * 2002-01-17 2008-12-23 Novartis Ag Methods of treatment and pharmaceutical composition
TWI322689B (en) * 2003-02-24 2010-04-01 Otsuka Pharma Co Ltd Method for treating severe heart failure and medicament therefor
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US20100004206A1 (en) 2005-12-27 2010-01-07 Makoto Komatsu Water-soluble benzoazepine compound and its pharmaceutical composition
JP5076327B2 (ja) * 2006-02-01 2012-11-21 味の素株式会社 分岐鎖アミノ酸の心不全適応
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
DK2146721T3 (da) * 2007-05-15 2013-07-22 Otsuka Pharma Co Ltd Fremgangsmåder til anvendelse af vasopressinantagonister med anthracyclin-kemoterapi-midler til reduktion af kardiotoksicitet og/eller forbedring af overlevelse
TWI405574B (zh) * 2007-06-21 2013-08-21 Otsuka Pharma Co Ltd 藥學固體製劑及其製造方法
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
ES2903231T3 (es) 2008-02-26 2022-03-31 Jenavalve Tech Inc Stent para el posicionamiento y anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente
JP2013526388A (ja) 2010-05-25 2013-06-24 イエナバルブ テクノロジー インク 人工心臓弁、及び人工心臓弁とステントを備える経カテーテル搬送体内プロテーゼ
JP5477413B2 (ja) * 2012-04-24 2014-04-23 味の素株式会社 分岐鎖アミノ酸の心不全適応
CN105491978A (zh) 2013-08-30 2016-04-13 耶拿阀门科技股份有限公司 用于假体瓣膜的径向可折叠框架及其制造方法
WO2016177562A1 (en) 2015-05-01 2016-11-10 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
JP7081749B2 (ja) 2016-05-13 2022-06-07 イエナバルブ テクノロジー インク 心臓弁プロテーゼ送達システム
CN110392557A (zh) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 心脏瓣膜模拟
CN110174474B (zh) * 2019-05-24 2022-02-18 石家庄四药有限公司 复方电解质注射液(ⅱ)中l-苹果酸异构体的检测方法
CN112121051B (zh) * 2020-09-30 2021-06-18 郑州大学 莫扎伐坦在制备抗消化道肿瘤药物中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5258510A (en) * 1989-10-20 1993-11-02 Otsuka Pharma Co Ltd Benzoheterocyclic compounds
US5753677A (en) 1989-10-20 1998-05-19 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
EP0450097B1 (en) 1989-10-20 1996-04-24 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
WO1994001113A1 (en) 1992-07-02 1994-01-20 Otsuka Pharmaceutical Company, Limited Oxytocin antagonist
JPH0680641A (ja) 1992-09-01 1994-03-22 Otsuka Pharmaceut Co Ltd 光学活性な５−ヒドロキシベンゾアゼピン誘導体の製造法
TW354762B (en) * 1993-02-23 1999-03-21 Otsuka Pharma Co Ltd Agent for prophylaxis or treatment of cataract
JP2694319B2 (ja) 1993-12-24 1997-12-24 大塚製薬株式会社 抗潰瘍剤
JP3002766B2 (ja) 1994-12-09 2000-01-24 大塚製薬株式会社 脳浮腫治療剤
JPH10120592A (ja) 1996-10-22 1998-05-12 Otsuka Pharmaceut Co Ltd メニエール病乃至メニエール症候群治療剤
JP4210355B2 (ja) * 1997-07-03 2009-01-14 大塚製薬株式会社 固形製剤組成物
US20030103983A1 (en) * 2002-05-09 2003-06-05 Pressler Milton Lethan Ace inhibitor-vasopressin antagonist combinations
BR0017074A (pt) 2000-01-26 2002-12-03 Warner Lambert Co Combinações de inibidor de ace-antagonista de vasopressina
US20030008860A1 (en) * 2002-05-09 2003-01-09 Bakker-Arkema Rebecca Guggemos Treatment of congestive heart failure
ATE367815T1 (de) * 2000-10-04 2007-08-15 Astellas Pharma Inc Verwendung von einem vasopressin-antagonisten wie conivaptan zur herstellung eines medikaments für die behandlung der pulmonalen hypertension
TWI322689B (en) * 2003-02-24 2010-04-01 Otsuka Pharma Co Ltd Method for treating severe heart failure and medicament therefor

Also Published As

Publication number Publication date
CN1700919A (zh) 2005-11-23
PL218069B1 (pl) 2014-10-31
MXPA05001623A (es) 2005-04-25
EP1596868A4 (en) 2006-03-29
RU2005102110A (ru) 2005-09-20
EP1596868B1 (en) 2008-10-22
CY1108583T1 (el) 2014-04-09
TW200418489A (en) 2004-10-01
NO20050569D0 (no) 2005-02-02
US7749993B2 (en) 2010-07-06
JP2011148806A (ja) 2011-08-04
RU2346689C2 (ru) 2009-02-20
TWI322689B (en) 2010-04-01
EP2000142A1 (en) 2008-12-10
AR043259A1 (es) 2005-07-20
KR20050105972A (ko) 2005-11-08
DE602004017283D1 (de) 2008-12-04
HK1084037A1 (en) 2006-07-21
EP1596868A1 (en) 2005-11-23
BRPI0405657A (pt) 2005-07-19
CN100577171C (zh) 2010-01-06
PL404315A1 (pl) 2013-08-05
US7423032B2 (en) 2008-09-09
AU2004212842B2 (en) 2009-01-08
ES2315640T3 (es) 2009-04-01
AU2004212842A1 (en) 2004-09-02
RU2008133654A (ru) 2010-02-20
WO2004073716A1 (en) 2004-09-02
MY143740A (en) 2011-07-15
US20080214523A1 (en) 2008-09-04
DK1596868T3 (da) 2008-12-08
PT1596868E (pt) 2009-01-14
PL373432A1 (en) 2005-08-22
NO335369B1 (no) 2014-12-01
AU2009201109A1 (en) 2009-04-09
US20050187210A1 (en) 2005-08-25
ATE411803T1 (de) 2008-11-15
AU2004212842B9 (en) 2009-03-05
KR100706727B1 (ko) 2007-04-12
CA2493475A1 (en) 2004-09-02
SI1596868T1 (sl) 2008-12-31
JP4771937B2 (ja) 2011-09-14
JP2006518731A (ja) 2006-08-17

Similar Documents

Publication Publication Date Title
NO20050569L (no) Fremgangsmate for behandling av alvorlig hjertesvikt og medikament for dette
IN2015DN01132A (no)
EA200300776A1 (ru) Производные фенэтаноламина для лечения респираторных заболеваний
BR0212078A (pt) Método de tratar ou prevenir uma doença relacionada com amilóide em um paciente, composição farmacêutica, composto quìmico, e, uso de um composto
MY142551A (en) Substituted diaryl heterocycles, process for their preparation and their use as medicaments
EA200601846A1 (ru) Содержащие бензоксазины лекарственные комбинации для лечения заболеваний дыхательных путей
EP1803721A4 (en) INNOVATIVE GLUCITOL DERIVATIVE, PRECURSOR OF THE MEDICINAL PRODUCT AND SALT THEREOF, AND A THERAPEUTIC AGENT FOR DIABETES CONTAINING THE SAME
NO20065904L (no) Terapeutiske forbindelser
IL165264A (en) Protein kinase inhibitors, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for treating protein kinase-associated diseases
RU95102778A (ru) Применение 2-фенил-3-ароилбензотиофенов для ингибирования потерь костной ткани и снижения уровня холестерина в сыворотке, фармацевтический препарат, содержащий 2-фенил-3-ароилбензотиофен
DE50311898D1 (de) Fredericamycin-derivate als arzneimittel zur tumorbehandlung
NO20060981L (no) Pyridazinderivater og deres anvendelse som terapeutiske midler
NO20073831L (no) Medikamenter for behandling eller forebygging av fibrotiske sykdommer
MXPA05007857A (es) Moduladores derivados de indol de receptores nucleares de hormonas esteroideas.
UA107578C2 (uk) Комбінована терапія при лікуванні діабету
RU2008119454A (ru) Лекарственное средство для защиты моторного нейрона у пациентов с боковым амиотрофическим склерозом
NO20064811L (no) 4-(5-aminometyl-2-fluor-fenyl)-piperidin-1-yl]-(4-brom-3-metyl-5-propoksy-tiofen-2-yl)-metanonhydroklorid som en inhibitor av mastcelletryptase
HK1079526A1 (en) A novel pyrazine compound and its use in the manufacture of a medicament for treating diseases related to serotonin
MY128014A (en) Thiol and thiocarbonyl derivatives which are useful as carboxypeptidase u inhibitors
RU2008126389A (ru) Производные 1,1- диоксотиоморфолинилиндолилметанона для применения в качестве модуляторов гистаминаз(н3)
MXPA05005790A (es) Aminoalcoxiindoles como ligandos del receptor 5-ht6 para el tratamiento de enfermedades del sistema nervioso central.
ATE366107T1 (de) Verwendung von sulfodehydroabietinsäure zur behandlung entzündlicher darmerkrankungen
ID29025A (id) Fenilalkenoilguanidina-fenilalkenoilguanidina yang disubstitusi asam empedu, proses pembuatannya, penggunaannya sebagai obat atau diaknostik dan obat-obat yang mengandungnya
AU2001246999A1 (en) New neurokinin antagonists for use as medicaments
SE9901572D0 (sv) New compounds