JP2004501183A5 - - Google Patents
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- JP2004501183A5 JP2004501183A5 JP2002504979A JP2002504979A JP2004501183A5 JP 2004501183 A5 JP2004501183 A5 JP 2004501183A5 JP 2002504979 A JP2002504979 A JP 2002504979A JP 2002504979 A JP2002504979 A JP 2002504979A JP 2004501183 A5 JP2004501183 A5 JP 2004501183A5
- Authority
- JP
- Japan
- Prior art keywords
- particles
- item
- pharmaceutical composition
- excipient
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000002245 particle Substances 0.000 description 36
- 238000000034 method Methods 0.000 description 20
- 239000000546 pharmaceutical excipient Substances 0.000 description 20
- 239000000463 material Substances 0.000 description 17
- 239000008194 pharmaceutical composition Substances 0.000 description 15
- 239000002131 composite material Substances 0.000 description 10
- 238000003801 milling Methods 0.000 description 5
- 238000000227 grinding Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 229940112141 dry powder inhaler Drugs 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000001694 spray drying Methods 0.000 description 2
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00113608.4 | 2000-06-27 | ||
| EP00113608 | 2000-06-27 | ||
| GB0029263.1 | 2000-11-30 | ||
| GB0029263A GB0029263D0 (en) | 2000-11-30 | 2000-11-30 | Method of making particles for use in a pharmaceutical composition |
| PCT/GB2001/001732 WO2001078694A2 (en) | 2000-04-17 | 2001-04-17 | Formulations for use in inhaler devices |
| GBPCT/GB01/01732 | 2001-04-17 | ||
| PCT/GB2001/002860 WO2002000197A1 (en) | 2000-06-27 | 2001-06-27 | Method of making particles for use in a pharmaceutical composition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004501183A JP2004501183A (ja) | 2004-01-15 |
| JP2004501183A5 true JP2004501183A5 (enExample) | 2008-07-10 |
| JP5698423B2 JP5698423B2 (ja) | 2015-04-08 |
Family
ID=26071085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002504979A Expired - Lifetime JP5698423B2 (ja) | 2000-06-27 | 2001-06-27 | 医薬組成物で使用するための粒子の製造法 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US7744855B2 (enExample) |
| EP (3) | EP1296651B2 (enExample) |
| JP (1) | JP5698423B2 (enExample) |
| KR (1) | KR100949539B1 (enExample) |
| CN (1) | CN100551358C (enExample) |
| AT (1) | ATE378039T1 (enExample) |
| CA (1) | CA2413692C (enExample) |
| DE (1) | DE60131399T3 (enExample) |
| DK (1) | DK1913939T3 (enExample) |
| ES (2) | ES2632461T3 (enExample) |
| IL (2) | IL153705A0 (enExample) |
| PT (2) | PT1913939T (enExample) |
| WO (1) | WO2002000197A1 (enExample) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9501841D0 (en) * | 1995-01-31 | 1995-03-22 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
| GB9515182D0 (en) * | 1995-07-24 | 1995-09-20 | Co Ordinated Drug Dev | Improvements in and relating to powders for use in dry powder inhalers |
| GB0009469D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
| PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| GB0009468D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formulations for use in inhaler devices |
| PT1913939T (pt) * | 2000-06-27 | 2017-07-19 | Vectura Ltd | Formulações para utilização em dispositivos inalatórios |
| PT2283817T (pt) | 2000-11-30 | 2016-08-22 | Vectura Ltd | Método de fabrico de partículas para utilização numa composição farmacêutica |
| AU2002220857A1 (en) * | 2000-11-30 | 2002-06-11 | Vectura Limited | Particles for use in a pharmaceutical composition |
| GB0208742D0 (en) * | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| US8337816B2 (en) | 2001-09-17 | 2012-12-25 | Glaxo Group Limited | Dry powder medicament formulations |
| US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
| CN102688224A (zh) * | 2003-04-14 | 2012-09-26 | 维克特拉有限公司 | 用于提高剂量效率的药物组合物和装置 |
| US7094545B2 (en) | 2003-04-30 | 2006-08-22 | Ferring Bv | Pharmaceutical composition as solid dosage form and method for manufacturing thereof |
| KR20060015316A (ko) | 2003-05-28 | 2006-02-16 | 넥타르 테라퓨틱스 | 아미노산 및/또는 인지질로 부분 또는 완전 코팅된수불용성 활성제 미립자의 제조를 위한 알코올성 수용액의분무 건조법 |
| WO2005004845A1 (en) * | 2003-07-11 | 2005-01-20 | Glaxo Group Limited | Pharmaceutical formulations comprising magnesium stearate |
| ATE301990T1 (de) | 2003-07-25 | 2005-09-15 | Ferring Bv | Pharmazeutische desmopressin-zubereitung als feste darreichungsform und methode zu ihrer herstellung |
| NZ545484A (en) * | 2003-09-15 | 2009-09-25 | Vectura Ltd | Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation |
| GB0321607D0 (en) * | 2003-09-15 | 2003-10-15 | Vectura Ltd | Manufacture of pharmaceutical compositions |
| GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
| GB0324918D0 (en) * | 2003-10-24 | 2003-11-26 | Glaxo Group Ltd | Composition |
| US7018653B2 (en) | 2003-12-29 | 2006-03-28 | Ferring B.V. | Method for preparing solid dosage form of desmopressin |
| DE102004011512B4 (de) * | 2004-03-08 | 2022-01-13 | Boehringer Ingelheim Vetmedica Gmbh | Pharmazeutische Zubereitung enthaltend Pimobendan |
| US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
| EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
| GB0409703D0 (en) | 2004-04-30 | 2004-06-02 | Vectura Ltd | Pharmaceutical compositions |
| GB0425758D0 (en) * | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
| GB0426301D0 (en) * | 2004-11-30 | 2004-12-29 | Vectura Ltd | Pharmaceutical formulations |
| US8623405B2 (en) * | 2005-01-28 | 2014-01-07 | Takeda Pharmaceutical Company Limited | Finely divided composition containing poorly water soluble substance |
| RU2007133547A (ru) | 2005-02-10 | 2009-03-20 | Глаксо Груп Лимитед (GB) | Способы получения лактозы с использованием методов предварительной сортировки и приготовляемые из нее фармацевтические композиции |
| ITMI20051999A1 (it) * | 2005-10-21 | 2007-04-22 | Eratech S R L | Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita' |
| GB0613161D0 (en) | 2006-06-30 | 2006-08-09 | Novartis Ag | Organic Compounds |
| WO2008000042A1 (en) | 2006-06-30 | 2008-01-03 | Iceutica Pty Ltd | Methods for the preparation of biologically active compounds in nanoparticulate form |
| EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
| ES2572157T3 (es) * | 2007-09-03 | 2016-05-30 | Nanotherapeutics Inc | Composiciones en forma de partículas para la administración de fármacos poco solubles |
| EP2080508A1 (en) | 2008-01-15 | 2009-07-22 | CHIESI FARMACEUTICI S.p.A. | Dry powder formulation comprising an anticholinergic drug |
| EP2296628B1 (en) | 2008-05-22 | 2014-05-14 | 3M Innovative Properties Company | Process for manufacturing flowable powder drug compositions |
| WO2009158300A1 (en) | 2008-06-26 | 2009-12-30 | 3M Innovative Properties Company | Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof |
| WO2010002613A2 (en) | 2008-07-02 | 2010-01-07 | 3M Innovative Properties Company | Method of making a dry powder pharmaceutical composition |
| MX2011005444A (es) | 2008-11-25 | 2011-06-09 | Boehringer Ingelheim Vetmed | Inhibidores de la fosfodiesterasa tipo iii (pde iii) o agentes sensibilizantes a iones de ca(2+) para el tratamiento de la cardiomiopatia hipertrofica. |
| MX354829B (es) | 2009-03-26 | 2018-03-22 | Pulmatrix Operating Co Inc | Formulaciones de polvo seco y metodos para el tratamiento de enfermedades pulmonares. |
| AU2010239161B2 (en) * | 2009-04-24 | 2014-10-09 | Iceutica Pty Ltd | Production of encapsulated nanoparticles at commercial scale |
| UA106231C2 (uk) | 2009-04-24 | 2014-08-11 | Айсьютика Пти Лтд | Разова доза фармацевтичної композиції індометацину (варіанти) |
| CA2759041A1 (en) * | 2009-04-24 | 2010-10-28 | Schering Corporation | Agglomerate formulations useful in dry powder inhalers |
| GB0921481D0 (en) | 2009-12-08 | 2010-01-20 | Vectura Ltd | Process and product |
| CA2784207C (en) * | 2009-12-14 | 2018-06-05 | Chiesi Farmaceutici S.P.A. | Antibiotic microparticles for inhalation |
| HUE038555T2 (hu) * | 2010-04-21 | 2018-10-29 | Chiesi Farm Spa | Eljárás csökkentett elektrosztatikus töltéssel rendelkezõ részecskék elõállítására |
| US9228785B2 (en) | 2010-05-04 | 2016-01-05 | Alexander Poltorak | Fractal heat transfer device |
| UA107499C2 (uk) | 2010-06-22 | 2015-01-12 | Chiesi Farm Spa | Склад сухого порошку, який містить антимускариновий засіб |
| NZ606548A (en) | 2010-08-03 | 2015-02-27 | Chiesi Farma Spa | Dry powder formulation comprising a phosphodiesterase inhibitor |
| CA2809666C (en) | 2010-08-30 | 2020-09-22 | Michael M. Lipp | Dry powder formulations and methods for treating pulmonary diseases |
| EP2464346A1 (en) | 2010-08-30 | 2012-06-20 | Pulmatrix, Inc. | Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder |
| RU2640921C2 (ru) | 2010-09-29 | 2018-01-12 | Пулмэтрикс, Инк. | Катионы одновалентных металлов сухих порошков для ингаляций |
| AU2011314007B2 (en) | 2010-09-29 | 2017-01-19 | Pulmatrix, Inc. | Cationic dry powders |
| TW201304822A (zh) | 2010-11-15 | 2013-02-01 | Vectura Ltd | 組成物及用途 |
| TW201306847A (zh) | 2010-11-30 | 2013-02-16 | Vectura Ltd | 組成物及用途 |
| JP2015509788A (ja) | 2012-02-29 | 2015-04-02 | パルマトリックス，インコーポレイテッド | 吸入に適した乾燥粉末 |
| EP3167876B1 (en) | 2012-03-15 | 2021-09-08 | Boehringer Ingelheim Vetmedica GmbH | Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof |
| US9763965B2 (en) * | 2012-04-13 | 2017-09-19 | Glaxosmithkline Intellectual Property Development Limited | Aggregate particles |
| CA2907566C (en) | 2013-04-01 | 2023-08-22 | Pulmatrix, Inc. | Tiotropium dry powders |
| ITMI20130571A1 (it) * | 2013-04-10 | 2014-10-11 | Zambon Spa | Composizione farmaceutica contenente budesonide e formoterolo |
| ITMI20130572A1 (it) * | 2013-04-10 | 2014-10-11 | Eratech Srl | Composizione comprendente almeno due polveri secche ottenute per spray dry per aumentare la stabilita' della formulazione |
| SI3569222T1 (sl) * | 2013-07-11 | 2024-10-30 | Chiesi Farmaceutici S.P.A. | Formulacija suhega praška, obsegajoča antiholinergik, kortikosteroid in beta-adrenergik, za dajanje z inhalacijo |
| DK3021832T3 (da) | 2013-07-19 | 2021-05-25 | Boehringer Ingelheim Vetmedica Gmbh | Konserverede etherificerede cyclodextrinderivater indeholdende flydende vandig farmaceutisk sammensætning |
| ES2593210T3 (es) | 2013-12-04 | 2016-12-07 | Boehringer Ingelheim Vetmedica Gmbh | Composiciones farmacéuticas mejoradas de pimobendán |
| CN112656780A (zh) | 2014-02-20 | 2021-04-16 | 奥迪托皮克股份有限公司 | 用于吸入的干粉制剂 |
| US9526734B2 (en) | 2014-06-09 | 2016-12-27 | Iceutica Pty Ltd. | Formulation of meloxicam |
| PL3179986T3 (pl) | 2014-07-31 | 2023-06-26 | Vectura Inc. | Suche formulacje w proszku do inhalacji |
| JP6684275B2 (ja) * | 2014-10-08 | 2020-04-22 | ザンボン ソシエタ ペル アチオニ | ブデソニド及びホルモテロールを含有する医薬組成物 |
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| AU2015338717B2 (en) | 2014-10-31 | 2018-12-20 | Glaxosmithkline Intellectual Property Development Limited | Powder formulation |
| MA40910A (fr) * | 2014-11-07 | 2017-09-12 | Civitas Therapeutics Inc | Poudres de rapamycine pour administration pulmonaire |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| EP3340982B1 (en) | 2015-08-26 | 2021-12-15 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
| EP3455219A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | AMINE-RELATED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| CN109414441A (zh) | 2016-06-27 | 2019-03-01 | 艾其林医药公司 | 治疗医学障碍的喹唑啉和吲哚化合物 |
| US10830545B2 (en) | 2016-07-12 | 2020-11-10 | Fractal Heatsink Technologies, LLC | System and method for maintaining efficiency of a heat sink |
| KR102632860B1 (ko) | 2017-03-01 | 2024-02-02 | 아칠리온 파르마세우티칼스 인코포레이티드 | 의학적 장애의 치료를 위한 아릴, 헤테로아릴, 및 헤테로사이클릭 약학적 화합물 |
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| US12269041B2 (en) | 2019-09-19 | 2025-04-08 | New Jersey Institute Of Technology | Spherical composite powder |
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| CN115362162A (zh) | 2020-02-20 | 2022-11-18 | 艾其林医药公司 | 用于治疗补体因子d介导的障碍的杂芳基化合物 |
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| PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| GB0009468D0 (en) | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formulations for use in inhaler devices |
| GB0009469D0 (en) * | 2000-04-17 | 2000-06-07 | Vectura Ltd | Improvements in or relating to formalities for use in inhaler devices |
| PT1913939T (pt) * | 2000-06-27 | 2017-07-19 | Vectura Ltd | Formulações para utilização em dispositivos inalatórios |
| AU2002220857A1 (en) | 2000-11-30 | 2002-06-11 | Vectura Limited | Particles for use in a pharmaceutical composition |
| PT2283817T (pt) | 2000-11-30 | 2016-08-22 | Vectura Ltd | Método de fabrico de partículas para utilização numa composição farmacêutica |
| US6966990B2 (en) | 2002-10-11 | 2005-11-22 | Ferro Corporation | Composite particles and method for preparing |
| US20060147389A1 (en) | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
| US9192915B2 (en) * | 2008-05-10 | 2015-11-24 | Brigham Young University | Porous composite particulate materials, methods of making and using same, and related apparatuses |
| AU2011209276B2 (en) * | 2010-01-27 | 2015-02-12 | Basf Se | Coating means comprising composite particles |
| US8491908B2 (en) * | 2010-06-01 | 2013-07-23 | Canon Kabushiki Kaisha | Composite particle, contrast agent for photoacoustic imaging, and method for producing the composite particle |
-
2001
- 2001-06-27 PT PT71205918T patent/PT1913939T/pt unknown
- 2001-06-27 PT PT01947612T patent/PT1296651E/pt unknown
- 2001-06-27 JP JP2002504979A patent/JP5698423B2/ja not_active Expired - Lifetime
- 2001-06-27 AT AT01947612T patent/ATE378039T1/de active
- 2001-06-27 IL IL15370501A patent/IL153705A0/xx active IP Right Grant
- 2001-06-27 US US10/312,488 patent/US7744855B2/en not_active Expired - Fee Related
- 2001-06-27 ES ES07120591.8T patent/ES2632461T3/es not_active Expired - Lifetime
- 2001-06-27 ES ES01947612T patent/ES2292598T3/es not_active Expired - Lifetime
- 2001-06-27 DK DK07120591.8T patent/DK1913939T3/en active
- 2001-06-27 WO PCT/GB2001/002860 patent/WO2002000197A1/en not_active Ceased
- 2001-06-27 DE DE60131399.2T patent/DE60131399T3/de not_active Expired - Lifetime
- 2001-06-27 EP EP01947612.6A patent/EP1296651B2/en not_active Expired - Lifetime
- 2001-06-27 EP EP07120591.8A patent/EP1913939B1/en not_active Expired - Lifetime
- 2001-06-27 CA CA2413692A patent/CA2413692C/en not_active Expired - Lifetime
- 2001-06-27 CN CNB018118887A patent/CN100551358C/zh not_active Expired - Lifetime
- 2001-06-27 KR KR1020027017595A patent/KR100949539B1/ko not_active Expired - Lifetime
- 2001-06-27 EP EP10185471.9A patent/EP2266549B1/en not_active Revoked
-
2002
- 2002-12-26 IL IL153705A patent/IL153705A/en unknown
-
2010
- 2010-05-18 US US12/782,283 patent/US9351928B2/en not_active Expired - Fee Related
-
2016
- 2016-05-02 US US15/144,770 patent/US20160243039A1/en not_active Abandoned
-
2017
- 2017-10-31 US US15/799,521 patent/US10561613B2/en not_active Expired - Fee Related
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