JP2003535057A5 - - Google Patents
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- JP2003535057A5 JP2003535057A5 JP2001585719A JP2001585719A JP2003535057A5 JP 2003535057 A5 JP2003535057 A5 JP 2003535057A5 JP 2001585719 A JP2001585719 A JP 2001585719A JP 2001585719 A JP2001585719 A JP 2001585719A JP 2003535057 A5 JP2003535057 A5 JP 2003535057A5
- Authority
- JP
- Japan
- Prior art keywords
- omega
- pharmaceutical composition
- weight
- water
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 14
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000003921 oil Substances 0.000 description 6
- 235000019198 oils Nutrition 0.000 description 6
- 239000002904 solvent Substances 0.000 description 5
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000006014 omega-3 oil Substances 0.000 description 4
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 description 4
- 229960004134 propofol Drugs 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 description 3
- 229940009662 edetate Drugs 0.000 description 3
- 235000020673 eicosapentaenoic acid Nutrition 0.000 description 3
- 229960005135 eicosapentaenoic acid Drugs 0.000 description 3
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 description 3
- 239000007764 o/w emulsion Substances 0.000 description 3
- 238000007911 parenteral administration Methods 0.000 description 3
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 description 2
- 235000020669 docosahexaenoic acid Nutrition 0.000 description 2
- 239000000932 sedative agent Substances 0.000 description 2
- 230000001624 sedative effect Effects 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 description 1
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 229940090949 docosahexaenoic acid Drugs 0.000 description 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 description 1
- 230000007760 free radical scavenging Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0012597.1A GB0012597D0 (en) | 2000-05-25 | 2000-05-25 | Formulation |
| GB0012597.1 | 2000-05-25 | ||
| PCT/GB2001/002259 WO2001089474A2 (en) | 2000-05-25 | 2001-05-22 | O/w emulsion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003535057A JP2003535057A (ja) | 2003-11-25 |
| JP2003535057A5 true JP2003535057A5 (https=) | 2008-05-08 |
Family
ID=9892262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001585719A Pending JP2003535057A (ja) | 2000-05-25 | 2001-05-22 | 処方物 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20030144356A1 (https=) |
| EP (1) | EP1289503B1 (https=) |
| JP (1) | JP2003535057A (https=) |
| KR (1) | KR20030009501A (https=) |
| CN (1) | CN1430503A (https=) |
| AT (1) | ATE365538T1 (https=) |
| AU (2) | AU5858801A (https=) |
| BR (1) | BR0111136A (https=) |
| CA (1) | CA2407764A1 (https=) |
| DE (1) | DE60129134T2 (https=) |
| ES (1) | ES2287128T3 (https=) |
| GB (1) | GB0012597D0 (https=) |
| IL (1) | IL152773A0 (https=) |
| MX (1) | MXPA02011532A (https=) |
| NO (1) | NO20025629L (https=) |
| NZ (1) | NZ522365A (https=) |
| WO (1) | WO2001089474A2 (https=) |
| ZA (1) | ZA200208853B (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1166368C (zh) * | 2003-02-26 | 2004-09-15 | 刘威 | 海狗油脂肪乳注射液、其制备方法及其在制备静脉注射剂中的应用 |
| US7780873B2 (en) * | 2004-02-23 | 2010-08-24 | Texas A&M University System | Bioactive complexes compositions and methods of use thereof |
| BRPI0512864B8 (pt) * | 2004-07-01 | 2021-05-25 | Johnson & Johnson Vision Care | composição oftálmica, uso de pelo menos um ácido graxo ômega-6 e pelo menos um ácido graxo ômega-3 e método para preparar a referida composição |
| CN100358513C (zh) * | 2005-04-07 | 2008-01-02 | 常州市第四制药厂有限公司 | 一种丙泊酚注射液的制备工艺 |
| KR20080043793A (ko) * | 2005-08-05 | 2008-05-19 | 바라트 쎄럼스 앤드 백신스 리미티드 | 방부 효능을 갖는 정맥 프로포폴 에멀젼 조성물 |
| US20070149617A1 (en) * | 2005-11-14 | 2007-06-28 | Deckelbaum Richard J | Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs |
| WO2008036353A2 (en) * | 2006-09-19 | 2008-03-27 | The Trustees Of Columbia University In The City Of New York | Omega-3 diglyceride emulsions |
| CN101411685B (zh) * | 2007-10-19 | 2011-04-20 | 上海医药工业研究院 | 一种静脉麻醉药2,6-二异丙基苯酚微乳组合物及其制备方法 |
| US20110071090A1 (en) * | 2009-03-11 | 2011-03-24 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle |
| US9034389B2 (en) | 2009-03-11 | 2015-05-19 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| US8993625B2 (en) | 2009-03-11 | 2015-03-31 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle |
| US8241672B2 (en) * | 2009-03-11 | 2012-08-14 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| US8496976B2 (en) | 2009-06-05 | 2013-07-30 | Allergan, Inc. | Artificial tears and therapeutic uses |
| US20110086914A1 (en) * | 2009-10-13 | 2011-04-14 | Bailes Julian E | Methods for Treating Traumatic Brain Injury |
| WO2011103514A1 (en) * | 2010-02-18 | 2011-08-25 | Martek Biosciences Corporation | Dha triglyceride emulsions |
| US20110200644A1 (en) * | 2010-02-18 | 2011-08-18 | Martek Biosciences Corporation | DHA Ester Emulsions |
| WO2011103512A1 (en) * | 2010-02-18 | 2011-08-25 | Martek Biosciences Corporation | Dha free fatty acid emulsions |
| US9675572B2 (en) | 2010-04-23 | 2017-06-13 | The United States Of America As Represented By The Secretary Of The Army | Intravenous omega-3 fatty acid compositions and method of use |
| US11236351B2 (en) | 2010-05-17 | 2022-02-01 | Dow Agrosciences Llc | Production of DHA and other LC PUFAs in plants |
| WO2011149854A2 (en) * | 2010-05-25 | 2011-12-01 | Eric Kuhrts | Stable formulations of fatty acids |
| EP2590625B1 (en) * | 2010-07-06 | 2017-09-20 | GlaxoSmithKline Biologicals SA | Cationic oil-in-water emulsions |
| US8658676B2 (en) | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
| EP2627173B2 (en) | 2010-10-12 | 2018-07-04 | Chiesi Farmaceutici S.p.A. | Clevidipine emulsion formulations containing antimicrobial agents |
| US20120251685A1 (en) * | 2011-04-04 | 2012-10-04 | Martek Biosciences Corporation | Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same |
| HRP20171431T1 (hr) * | 2011-06-15 | 2017-12-15 | Stable Solutions Llc | Terapijska parenteralna primjena krilovog ulja |
| US10052352B2 (en) | 2011-06-15 | 2018-08-21 | Stable Solutions Llc | Therapeutic application of parenteral krill oil |
| TW201307553A (zh) * | 2011-07-26 | 2013-02-16 | Dow Agrosciences Llc | 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術 |
| CN102366404B (zh) * | 2011-10-20 | 2015-10-07 | 四川百利药业有限责任公司 | 一种丙泊酚中/长链脂肪乳剂 |
| WO2014033751A2 (en) * | 2012-08-16 | 2014-03-06 | Emcure Pharmaceuticals Limited | Pharmaceutical composition of propofol |
| EP2978307B1 (en) | 2013-03-28 | 2018-12-26 | The Trustees of Columbia University in the City of New York | Reperfusion with omega-3 glycerides promotes donor organ protection for transplantation |
| ES2607715B1 (es) * | 2015-10-01 | 2018-01-17 | Solutex Na, Lcc | Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5637404A (en) * | 1992-01-31 | 1997-06-10 | Aluminum Company Of America | Reflective aluminum strip |
| US5478414A (en) * | 1992-01-31 | 1995-12-26 | Aluminum Company Of America | Reflective aluminum strip, protected with fluoropolymer coating and a laminate of the strip with a thermoplastic polymer |
| BR9506681A (pt) * | 1994-02-04 | 1997-11-18 | Scotia Lipidteknik Ab | Emulsão oleo em água e composição farmacêutica |
| GB9405593D0 (en) * | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
| ES2211151T3 (es) * | 1998-08-19 | 2004-07-01 | Skyepharma Canada Inc. | Dispersiones acuosas inyectables de propofol. |
| US6140374A (en) * | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
| US6582723B2 (en) * | 2001-05-03 | 2003-06-24 | Wayne F. Gorsek | Cancer immune composition for prevention and treatment of individuals |
-
2000
- 2000-05-25 GB GBGB0012597.1A patent/GB0012597D0/en not_active Ceased
-
2001
- 2001-05-22 IL IL15277301A patent/IL152773A0/xx unknown
- 2001-05-22 MX MXPA02011532A patent/MXPA02011532A/es active IP Right Grant
- 2001-05-22 DE DE60129134T patent/DE60129134T2/de not_active Expired - Fee Related
- 2001-05-22 CN CN01810092A patent/CN1430503A/zh active Pending
- 2001-05-22 JP JP2001585719A patent/JP2003535057A/ja active Pending
- 2001-05-22 CA CA002407764A patent/CA2407764A1/en not_active Abandoned
- 2001-05-22 KR KR1020027015889A patent/KR20030009501A/ko not_active Ceased
- 2001-05-22 EP EP01931897A patent/EP1289503B1/en not_active Expired - Lifetime
- 2001-05-22 ES ES01931897T patent/ES2287128T3/es not_active Expired - Lifetime
- 2001-05-22 BR BR0111136-1A patent/BR0111136A/pt not_active Application Discontinuation
- 2001-05-22 US US10/275,912 patent/US20030144356A1/en not_active Abandoned
- 2001-05-22 AU AU5858801A patent/AU5858801A/xx active Pending
- 2001-05-22 NZ NZ522365A patent/NZ522365A/en unknown
- 2001-05-22 AU AU2001258588A patent/AU2001258588B2/en not_active Ceased
- 2001-05-22 AT AT01931897T patent/ATE365538T1/de not_active IP Right Cessation
- 2001-05-22 WO PCT/GB2001/002259 patent/WO2001089474A2/en not_active Ceased
-
2002
- 2002-10-31 ZA ZA200208853A patent/ZA200208853B/en unknown
- 2002-11-22 NO NO20025629A patent/NO20025629L/no not_active Application Discontinuation
-
2006
- 2006-03-30 US US11/392,934 patent/US20060257433A1/en not_active Abandoned
-
2008
- 2008-04-11 US US12/081,240 patent/US20080312338A1/en not_active Abandoned
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