JP2003535057A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003535057A5 JP2003535057A5 JP2001585719A JP2001585719A JP2003535057A5 JP 2003535057 A5 JP2003535057 A5 JP 2003535057A5 JP 2001585719 A JP2001585719 A JP 2001585719A JP 2001585719 A JP2001585719 A JP 2001585719A JP 2003535057 A5 JP2003535057 A5 JP 2003535057A5
- Authority
- JP
- Japan
- Prior art keywords
- omega
- pharmaceutical composition
- weight
- water
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 14
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000003921 oil Substances 0.000 description 6
- 235000019198 oils Nutrition 0.000 description 6
- 239000002904 solvent Substances 0.000 description 5
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000006014 omega-3 oil Substances 0.000 description 4
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 description 4
- 229960004134 propofol Drugs 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 description 3
- 229940009662 edetate Drugs 0.000 description 3
- 235000020673 eicosapentaenoic acid Nutrition 0.000 description 3
- 229960005135 eicosapentaenoic acid Drugs 0.000 description 3
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 description 3
- 239000007764 o/w emulsion Substances 0.000 description 3
- 238000007911 parenteral administration Methods 0.000 description 3
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 description 2
- 235000020669 docosahexaenoic acid Nutrition 0.000 description 2
- 239000000932 sedative agent Substances 0.000 description 2
- 230000001624 sedative effect Effects 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 description 1
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 229940090949 docosahexaenoic acid Drugs 0.000 description 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 description 1
- 230000007760 free radical scavenging Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0012597.1 | 2000-05-25 | ||
| GBGB0012597.1A GB0012597D0 (en) | 2000-05-25 | 2000-05-25 | Formulation |
| PCT/GB2001/002259 WO2001089474A2 (en) | 2000-05-25 | 2001-05-22 | O/w emulsion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003535057A JP2003535057A (ja) | 2003-11-25 |
| JP2003535057A5 true JP2003535057A5 (https=) | 2008-05-08 |
Family
ID=9892262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001585719A Pending JP2003535057A (ja) | 2000-05-25 | 2001-05-22 | 処方物 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20030144356A1 (https=) |
| EP (1) | EP1289503B1 (https=) |
| JP (1) | JP2003535057A (https=) |
| KR (1) | KR20030009501A (https=) |
| CN (1) | CN1430503A (https=) |
| AT (1) | ATE365538T1 (https=) |
| AU (2) | AU2001258588B2 (https=) |
| BR (1) | BR0111136A (https=) |
| CA (1) | CA2407764A1 (https=) |
| DE (1) | DE60129134T2 (https=) |
| ES (1) | ES2287128T3 (https=) |
| GB (1) | GB0012597D0 (https=) |
| IL (1) | IL152773A0 (https=) |
| MX (1) | MXPA02011532A (https=) |
| NO (1) | NO20025629L (https=) |
| NZ (1) | NZ522365A (https=) |
| WO (1) | WO2001089474A2 (https=) |
| ZA (1) | ZA200208853B (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1166368C (zh) * | 2003-02-26 | 2004-09-15 | 刘威 | 海狗油脂肪乳注射液、其制备方法及其在制备静脉注射剂中的应用 |
| US7780873B2 (en) * | 2004-02-23 | 2010-08-24 | Texas A&M University System | Bioactive complexes compositions and methods of use thereof |
| AU2005262392A1 (en) * | 2004-07-01 | 2006-01-19 | Johnson & Johnson Vision Care, Inc. | Compositions and methods for treating eye disorders and conditions |
| CN100358513C (zh) * | 2005-04-07 | 2008-01-02 | 常州市第四制药厂有限公司 | 一种丙泊酚注射液的制备工艺 |
| ATE420625T1 (de) * | 2005-08-05 | 2009-01-15 | Bharat Serums & Vaccines Ltd | Intravenöse propofol-emulsionszusammensetzungen mit konservierendem effekt |
| US20070149617A1 (en) * | 2005-11-14 | 2007-06-28 | Deckelbaum Richard J | Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs |
| WO2008036353A2 (en) * | 2006-09-19 | 2008-03-27 | The Trustees Of Columbia University In The City Of New York | Omega-3 diglyceride emulsions |
| CN101411685B (zh) * | 2007-10-19 | 2011-04-20 | 上海医药工业研究院 | 一种静脉麻醉药2,6-二异丙基苯酚微乳组合物及其制备方法 |
| US9034389B2 (en) | 2009-03-11 | 2015-05-19 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| US8993625B2 (en) | 2009-03-11 | 2015-03-31 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle |
| US20110071090A1 (en) * | 2009-03-11 | 2011-03-24 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle |
| US8241672B2 (en) * | 2009-03-11 | 2012-08-14 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| MX358504B (es) | 2009-06-05 | 2018-08-21 | Allergan Inc | Lagrimas artificiales y usos terapeuticos. |
| WO2011047091A1 (en) * | 2009-10-13 | 2011-04-21 | Martek Biosciences Corporation | Methods for treating traumatic brain injury |
| US20110206741A1 (en) * | 2010-02-18 | 2011-08-25 | Martek Biosciences Corporation | DHA Triglyceride Emulsions |
| US20110200645A1 (en) * | 2010-02-18 | 2011-08-18 | Martek Biosciences Corporation | DHA Free Fatty Acid Emulsions |
| US20110200644A1 (en) * | 2010-02-18 | 2011-08-18 | Martek Biosciences Corporation | DHA Ester Emulsions |
| WO2011133841A2 (en) * | 2010-04-23 | 2011-10-27 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Intravenous omega-3 fatty acid compositions & method of use |
| US11236351B2 (en) | 2010-05-17 | 2022-02-01 | Dow Agrosciences Llc | Production of DHA and other LC PUFAs in plants |
| JP2013526605A (ja) * | 2010-05-25 | 2013-06-24 | エリック カーツ， | 脂肪酸の安定な処方物 |
| NZ606591A (en) * | 2010-07-06 | 2015-02-27 | Novartis Ag | Cationic oil-in-water emulsions |
| PL2627173T5 (pl) | 2010-10-12 | 2019-11-29 | Chiesi Farm Spa | Formulacje emulsyjne klewidypiny zawierające środki przeciw mikrobom |
| US8658676B2 (en) | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
| US20120251685A1 (en) * | 2011-04-04 | 2012-10-04 | Martek Biosciences Corporation | Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same |
| US10052352B2 (en) | 2011-06-15 | 2018-08-21 | Stable Solutions Llc | Therapeutic application of parenteral krill oil |
| EP2720701B1 (en) * | 2011-06-15 | 2017-08-09 | Stable Solutions Llc | Therapeutic application of parenteral krill oil |
| TW201307553A (zh) | 2011-07-26 | 2013-02-16 | Dow Agrosciences Llc | 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術 |
| CN102366404B (zh) * | 2011-10-20 | 2015-10-07 | 四川百利药业有限责任公司 | 一种丙泊酚中/长链脂肪乳剂 |
| WO2014033751A2 (en) * | 2012-08-16 | 2014-03-06 | Emcure Pharmaceuticals Limited | Pharmaceutical composition of propofol |
| HK1221119A1 (zh) | 2013-03-28 | 2017-05-26 | The Trustees Of Columbia University In The City Of New York | 用omega-3甘油酯再灌注促进对用於移植的供体器官的保护 |
| ES2607715B1 (es) * | 2015-10-01 | 2018-01-17 | Solutex Na, Lcc | Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478414A (en) * | 1992-01-31 | 1995-12-26 | Aluminum Company Of America | Reflective aluminum strip, protected with fluoropolymer coating and a laminate of the strip with a thermoplastic polymer |
| US5637404A (en) * | 1992-01-31 | 1997-06-10 | Aluminum Company Of America | Reflective aluminum strip |
| WO1995020943A1 (en) * | 1994-02-04 | 1995-08-10 | Scotia Lipidteknik Ab | Oil-in-water emulsions |
| GB9405593D0 (en) * | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
| DE69912441T2 (de) * | 1998-08-19 | 2004-08-19 | Skyepharma Canada Inc., Verdun | Injizierbare wässerige propofoldispersionen |
| US6140374A (en) * | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
| US6582723B2 (en) * | 2001-05-03 | 2003-06-24 | Wayne F. Gorsek | Cancer immune composition for prevention and treatment of individuals |
-
2000
- 2000-05-25 GB GBGB0012597.1A patent/GB0012597D0/en not_active Ceased
-
2001
- 2001-05-22 NZ NZ522365A patent/NZ522365A/en unknown
- 2001-05-22 WO PCT/GB2001/002259 patent/WO2001089474A2/en not_active Ceased
- 2001-05-22 AT AT01931897T patent/ATE365538T1/de not_active IP Right Cessation
- 2001-05-22 CN CN01810092A patent/CN1430503A/zh active Pending
- 2001-05-22 DE DE60129134T patent/DE60129134T2/de not_active Expired - Fee Related
- 2001-05-22 AU AU2001258588A patent/AU2001258588B2/en not_active Ceased
- 2001-05-22 KR KR1020027015889A patent/KR20030009501A/ko not_active Ceased
- 2001-05-22 EP EP01931897A patent/EP1289503B1/en not_active Expired - Lifetime
- 2001-05-22 ES ES01931897T patent/ES2287128T3/es not_active Expired - Lifetime
- 2001-05-22 US US10/275,912 patent/US20030144356A1/en not_active Abandoned
- 2001-05-22 MX MXPA02011532A patent/MXPA02011532A/es active IP Right Grant
- 2001-05-22 CA CA002407764A patent/CA2407764A1/en not_active Abandoned
- 2001-05-22 AU AU5858801A patent/AU5858801A/xx active Pending
- 2001-05-22 JP JP2001585719A patent/JP2003535057A/ja active Pending
- 2001-05-22 BR BR0111136-1A patent/BR0111136A/pt not_active Application Discontinuation
- 2001-05-22 IL IL15277301A patent/IL152773A0/xx unknown
-
2002
- 2002-10-31 ZA ZA200208853A patent/ZA200208853B/en unknown
- 2002-11-22 NO NO20025629A patent/NO20025629L/no not_active Application Discontinuation
-
2006
- 2006-03-30 US US11/392,934 patent/US20060257433A1/en not_active Abandoned
-
2008
- 2008-04-11 US US12/081,240 patent/US20080312338A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2003535057A5 (https=) | ||
| ES2181662T3 (es) | Nanoemulsion a base de polimeros anionicos, y sus usos especialmente en los campos cosmetico, dermatologico, farmaceutio, y/u optalmologico. | |
| US20220202768A1 (en) | Dihydromyricetin nanoemulsion formulations and methods for forming them | |
| ES2881885T3 (es) | Composiciones que comprenden una mezcla de aceites de ácidos grasos que comprende EPA y DHA en forma de ácido libre y un tensioactivo, y procedimientos y usos de las mismas | |
| WO2001089474A3 (en) | O/w emulsion | |
| Inapurapu et al. | Development and characterization of ω-3 fatty acid nanoemulsions with improved physicochemical stability and bioaccessibility | |
| JP2002541086A5 (https=) | ||
| JP2010524992A5 (https=) | ||
| ATE380541T1 (de) | Herstellung von vitaminemulsionen und konzentrate davon | |
| JPS5793910A (en) | Preparation of emulsion for intravenous injection | |
| JP2016512828A (ja) | ラセカドトリル脂質組成物 | |
| CA2937167C (en) | Composition comprising epa and dha triglycerides for parenteral administration | |
| JP2015522031A (ja) | ラセカドトリル脂質組成物 | |
| JP2003505424A5 (https=) | ||
| US8895074B2 (en) | Therapeutic application of parenteral krill oil | |
| JP2019085349A (ja) | 難溶性物質を含有する経口摂取用組成物、難溶性物質の消化管吸収性の向上方法及び難溶性物質を含有する水中油型乳化物の胃内での乳化安定化方法 | |
| RU2839882C1 (ru) | Микроэмульсионная лекарственная форма для перорального введения | |
| JPH10330250A (ja) | メナテトレノン油性製剤 | |
| JPH04338333A (ja) | プロスタグランジンｅ１脂肪乳剤 | |
| JPH01113315A (ja) | ビタミンｋ↓２含有脂肪乳剤 | |
| PL210178B1 (pl) | Sposób wytwarzania mikroemulsji stabilizowanej surfaktantami | |
| Costa et al. | Control of Lipid Oxidation in Oil-in Water | |
| JPH04108732A (ja) | Ｐａｆ拮抗剤含有脂肪乳剤 | |
| JP2006248928A (ja) | メナテトレノン含有医薬組成物 | |
| JP2004210688A (ja) | 脂肪乳剤のプレフィルドシリンジ製剤およびその製造方法 |