|
US4879236A
(en)
|
1984-05-16 |
1989-11-07 |
The Texas A&M University System |
Method for producing a recombinant baculovirus expression vector
|
|
US4957858A
(en)
|
1986-04-16 |
1990-09-18 |
The Salk Instute For Biological Studies |
Replicative RNA reporter systems
|
|
EP0232967B1
(en)
|
1986-01-10 |
1993-04-28 |
Amoco Corporation |
Competitive homogeneous assay
|
|
EP0266032A1
(en)
|
1986-08-29 |
1988-05-04 |
Beecham Group Plc |
Modified fibrinolytic enzyme
|
|
AU622104B2
(en)
|
1987-03-11 |
1992-04-02 |
Sangtec Molecular Diagnostics Ab |
Method of assaying of nucleic acids, a reagent combination and kit therefore
|
|
IL86724A
(en)
|
1987-06-19 |
1995-01-24 |
Siska Diagnostics Inc |
Methods and kits for amplification and testing of nucleic acid sequences
|
|
AU622426B2
(en)
|
1987-12-11 |
1992-04-09 |
Abbott Laboratories |
Assay using template-dependent nucleic acid probe reorganization
|
|
WO1989006700A1
(en)
|
1988-01-21 |
1989-07-27 |
Genentech, Inc. |
Amplification and detection of nucleic acid sequences
|
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
|
EP0365627B1
(en)
|
1988-03-24 |
1993-12-22 |
University Of Iowa Research Foundation |
Catalytic hybridization systems for the detection of nucleic acid sequences based on their activity as cofactors in catalytic reactions in which a complementary labeled nucleic acid probe is cleaved
|
|
US5932413A
(en)
|
1988-04-01 |
1999-08-03 |
Celebuski; Joseph Eugene |
DNA probe assay using neutrally charged probe strands
|
|
US5858652A
(en)
|
1988-08-30 |
1999-01-12 |
Abbott Laboratories |
Detection and amplification of target nucleic acid sequences
|
|
US4932207A
(en)
|
1988-12-28 |
1990-06-12 |
Sundstrand Corporation |
Segmented seal plate for a turbine engine
|
|
US5856092A
(en)
|
1989-02-13 |
1999-01-05 |
Geneco Pty Ltd |
Detection of a nucleic acid sequence or a change therein
|
|
US5925525A
(en)
|
1989-06-07 |
1999-07-20 |
Affymetrix, Inc. |
Method of identifying nucleotide differences
|
|
US5849481A
(en)
|
1990-07-27 |
1998-12-15 |
Chiron Corporation |
Nucleic acid hybridization assays employing large comb-type branched polynucleotides
|
|
US5645987A
(en)
|
1990-09-21 |
1997-07-08 |
Amgen Inc. |
Enzymatic synthesis of oligonucleotides
|
|
US5846717A
(en)
|
1996-01-24 |
1998-12-08 |
Third Wave Technologies, Inc. |
Detection of nucleic acid sequences by invader-directed cleavage
|
|
US5849486A
(en)
|
1993-11-01 |
1998-12-15 |
Nanogen, Inc. |
Methods for hybridization analysis utilizing electrically controlled hybridization
|
|
US5846708A
(en)
|
1991-11-19 |
1998-12-08 |
Massachusetts Institiute Of Technology |
Optical and electrical methods and apparatus for molecule detection
|
|
WO1993020235A1
(en)
|
1992-04-01 |
1993-10-14 |
The Johns Hopkins University School Of Medicine |
Methods of detecting mammalian nucleic acids isolated from stool specimen and reagents therefor
|
|
US5792751A
(en)
|
1992-04-13 |
1998-08-11 |
Baylor College Of Medicine |
Tranformation of cells associated with fluid spaces
|
|
US5843640A
(en)
|
1992-06-19 |
1998-12-01 |
Northwestern University |
Method of simultaneously detecting amplified nucleic acid sequences and cellular antigens in cells
|
|
DE4228457A1
(de)
|
1992-08-27 |
1994-04-28 |
Beiersdorf Ag |
Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
|
|
US5861244A
(en)
|
1992-10-29 |
1999-01-19 |
Profile Diagnostic Sciences, Inc. |
Genetic sequence assay using DNA triple strand formation
|
|
US5707863A
(en)
|
1993-02-25 |
1998-01-13 |
General Hospital Corporation |
Tumor suppressor gene merlin
|
|
US5658751A
(en)
|
1993-04-13 |
1997-08-19 |
Molecular Probes, Inc. |
Substituted unsymmetrical cyanine dyes with selected permeability
|
|
GB9311386D0
(en)
|
1993-06-02 |
1993-07-21 |
Pna Diagnostics As |
Nucleic acid analogue assay procedures
|
|
US5846709A
(en)
|
1993-06-15 |
1998-12-08 |
Imclone Systems Incorporated |
Chemical process for amplifying and detecting nucleic acid sequences
|
|
FR2708288B1
(fr)
|
1993-07-26 |
1995-09-01 |
Bio Merieux |
Procédé d'amplification d'acides nucléiques par transcription utilisant le déplacement, réactifs et nécessaire pour la mise en Óoeuvre de ce procédé.
|
|
US5925517A
(en)
|
1993-11-12 |
1999-07-20 |
The Public Health Research Institute Of The City Of New York, Inc. |
Detectably labeled dual conformation oligonucleotide probes, assays and kits
|
|
GB2284208A
(en)
|
1993-11-25 |
1995-05-31 |
Pna Diagnostics As |
Nucleic acid analogues with a chelating functionality for metal ions
|
|
EP0663447B1
(en)
|
1993-12-28 |
2003-07-09 |
Eiken Chemical Co., Ltd. |
Method of detecting a specific polynucleotide
|
|
US5928905A
(en)
|
1995-04-18 |
1999-07-27 |
Glaxo Group Limited |
End-complementary polymerase reaction
|
|
US5851770A
(en)
|
1994-04-25 |
1998-12-22 |
Variagenics, Inc. |
Detection of mismatches by resolvase cleavage using a magnetic bead support
|
|
NZ287118A
(en)
|
1994-05-28 |
1999-01-28 |
Tepnel Medical Ltd |
Method of detecting and amplifying oligonucleotides
|
|
US5942391A
(en)
|
1994-06-22 |
1999-08-24 |
Mount Sinai School Of Medicine |
Nucleic acid amplification method: ramification-extension amplification method (RAM)
|
|
FR2722208B1
(fr)
|
1994-07-05 |
1996-10-04 |
Inst Nat Sante Rech Med |
Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique
|
|
US5849483A
(en)
|
1994-07-28 |
1998-12-15 |
Ig Laboratories, Inc. |
High throughput screening method for sequences or genetic alterations in nucleic acids
|
|
JP3102800B2
(ja)
|
1994-08-19 |
2000-10-23 |
パーキン−エルマー コーポレイション |
増幅及び連結反応の共役法
|
|
US5599668A
(en)
|
1994-09-22 |
1997-02-04 |
Abbott Laboratories |
Light scattering optical waveguide method for detecting specific binding events
|
|
US5871986A
(en)
|
1994-09-23 |
1999-02-16 |
The General Hospital Corporation |
Use of a baculovirus to express and exogenous gene in a mammalian cell
|
|
EP0709466B1
(en)
|
1994-10-28 |
2006-09-27 |
Gen-Probe Incorporated |
Compositions and methods for the simultaneous detection and quantification of multiple specific nucleic acid sequences
|
|
US5935825A
(en)
|
1994-11-18 |
1999-08-10 |
Shimadzu Corporation |
Process and reagent for amplifying nucleic acid sequences
|
|
US5866337A
(en)
|
1995-03-24 |
1999-02-02 |
The Trustees Of Columbia University In The City Of New York |
Method to detect mutations in a nucleic acid using a hybridization-ligation procedure
|
|
US5843650A
(en)
|
1995-05-01 |
1998-12-01 |
Segev; David |
Nucleic acid detection and amplification by chemical linkage of oligonucleotides
|
|
US5929227A
(en)
|
1995-07-12 |
1999-07-27 |
The Regents Of The University Of California |
Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores
|
|
US5916779A
(en)
|
1995-09-21 |
1999-06-29 |
Becton, Dickinson And Company |
Strand displacement amplification of RNA targets
|
|
US5866331A
(en)
|
1995-10-20 |
1999-02-02 |
University Of Massachusetts |
Single molecule detection by in situ hybridization
|
|
JP2000505781A
(ja)
|
1995-11-13 |
2000-05-16 |
ケンブリッジ ニューロサイエンス インコーポレイテッド |
非視覚性感覚上皮の疾患の治療方法
|
|
US5612473A
(en)
|
1996-01-16 |
1997-03-18 |
Gull Laboratories |
Methods, kits and solutions for preparing sample material for nucleic acid amplification
|
|
US5851772A
(en)
|
1996-01-29 |
1998-12-22 |
University Of Chicago |
Microchip method for the enrichment of specific DNA sequences
|
|
US5837681A
(en)
|
1996-02-23 |
1998-11-17 |
Amgen Inc. |
Method for treating sensorineural hearing loss using glial cell line-derived neurotrophic factor (GDNF) protein product
|
|
US5929041A
(en)
|
1996-02-23 |
1999-07-27 |
Amgen Inc. |
Method for preventing and treating sensorineural hearing loss and vestibular disorders using glial cell line-derived neurotrophic factor(GDNF) protein product
|
|
US5928906A
(en)
|
1996-05-09 |
1999-07-27 |
Sequenom, Inc. |
Process for direct sequencing during template amplification
|
|
US5939291A
(en)
|
1996-06-14 |
1999-08-17 |
Sarnoff Corporation |
Microfluidic method for nucleic acid amplification
|
|
US5912124A
(en)
|
1996-06-14 |
1999-06-15 |
Sarnoff Corporation |
Padlock probe detection
|
|
AU3591597A
(en)
|
1996-06-28 |
1998-01-21 |
Regents Of The University Of California, The |
Transformation and genetherapy of cells of the inner ear
|
|
US5866336A
(en)
|
1996-07-16 |
1999-02-02 |
Oncor, Inc. |
Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
|
|
US5853990A
(en)
|
1996-07-26 |
1998-12-29 |
Edward E. Winger |
Real time homogeneous nucleotide assay
|
|
US5928870A
(en)
|
1997-06-16 |
1999-07-27 |
Exact Laboratories, Inc. |
Methods for the detection of loss of heterozygosity
|
|
US5849546A
(en)
|
1996-09-13 |
1998-12-15 |
Epicentre Technologies Corporation |
Methods for using mutant RNA polymerases with reduced discrimination between non-canonical and canonical nucleoside triphosphates
|
|
WO1998013048A1
(en)
|
1996-09-27 |
1998-04-02 |
Trustees Of The University Of Pennsylvania |
Novel methods for inducing proliferation in auditory receptor epithelium
|
|
US5853992A
(en)
|
1996-10-04 |
1998-12-29 |
The Regents Of The University Of California |
Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels
|
|
US5853993A
(en)
|
1996-10-21 |
1998-12-29 |
Hewlett-Packard Company |
Signal enhancement method and kit
|
|
US6593290B1
(en)
|
1996-11-01 |
2003-07-15 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
US5900481A
(en)
|
1996-11-06 |
1999-05-04 |
Sequenom, Inc. |
Bead linkers for immobilizing nucleic acids to solid supports
|
|
US5905024A
(en)
|
1996-12-17 |
1999-05-18 |
University Of Chicago |
Method for performing site-specific affinity fractionation for use in DNA sequencing
|
|
US5846729A
(en)
|
1997-02-27 |
1998-12-08 |
Lorne Park Research, Inc. |
Assaying nucleotides in solution using a fluorescent intensity quenching effect
|
|
US5849497A
(en)
|
1997-04-03 |
1998-12-15 |
The Research Foundation Of State University Of New York |
Specific inhibition of the polymerase chain reaction using a non-extendable oligonucleotide blocker
|
|
US5846726A
(en)
|
1997-05-13 |
1998-12-08 |
Becton, Dickinson And Company |
Detection of nucleic acids by fluorescence quenching
|
|
US5928869A
(en)
|
1997-05-30 |
1999-07-27 |
Becton, Dickinson And Company |
Detection of nucleic acids by fluorescence quenching
|
|
US5919626A
(en)
|
1997-06-06 |
1999-07-06 |
Orchid Bio Computer, Inc. |
Attachment of unmodified nucleic acids to silanized solid phase surfaces
|
|
US6043221A
(en)
|
1997-07-30 |
2000-03-28 |
Amgen Inc. |
Method for preventing and treating hearing loss using a neuturin protein product
|
|
WO1999006034A1
(en)
|
1997-08-01 |
1999-02-11 |
Baylor College Of Medicine |
Coup-tfi directed therapies in the treatment of disease
|
|
US5916776A
(en)
|
1997-08-27 |
1999-06-29 |
Sarnoff Corporation |
Amplification method for a polynucleotide
|
|
US5935791A
(en)
|
1997-09-23 |
1999-08-10 |
Becton, Dickinson And Company |
Detection of nucleic acids by fluorescence quenching
|
|
US5932451A
(en)
|
1997-11-19 |
1999-08-03 |
Incyte Pharmaceuticals, Inc. |
Method for unbiased mRNA amplification
|
|
DE19807426A1
(de)
|
1998-02-23 |
1999-10-14 |
Otogene Biotechnologische Fors |
Verfahren zur Behandlung von Erkrankungen oder Störungen des Innenohrs
|
|
AU1223500A
(en)
|
1998-10-21 |
2000-05-08 |
Jonathan Kil |
Methods for stimulating the regeneration of inner ear cells
|
|
KR100627754B1
(ko)
|
1998-11-07 |
2006-09-26 |
제넨테크, 인크. |
Ｈｅｒ2 및(또는) ｈｅｒ3 수용체에 대한 리간드를 이용한내이 모 세포 증식의 향상 방법
|
|
US8312249B1
(en)
|
2008-10-10 |
2012-11-13 |
Apple Inc. |
Dynamic trampoline and structured code generation in a signed code environment
|
|
FR2957821B1
(fr)
|
2010-03-24 |
2014-08-29 |
Inst Francais Du Petrole |
Nouvelle zone de regeneration du catalyseur divisee en secteurs pour unites catalytiques regeneratives
|