JP2021530227A5 - - Google Patents
Info
- Publication number
- JP2021530227A5 JP2021530227A5 JP2021500888A JP2021500888A JP2021530227A5 JP 2021530227 A5 JP2021530227 A5 JP 2021530227A5 JP 2021500888 A JP2021500888 A JP 2021500888A JP 2021500888 A JP2021500888 A JP 2021500888A JP 2021530227 A5 JP2021530227 A5 JP 2021530227A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- composition according
- acid vector
- item
- sequence
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024079983A JP2024109708A (ja) | 2018-07-13 | 2024-05-16 | 非症候性感音性聴力喪失の治療方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862697652P | 2018-07-13 | 2018-07-13 | |
| US62/697,652 | 2018-07-13 | ||
| PCT/US2019/041625 WO2020014625A1 (en) | 2018-07-13 | 2019-07-12 | Methods of treating non-syndromic sensorineural hearing loss |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024079983A Division JP2024109708A (ja) | 2018-07-13 | 2024-05-16 | 非症候性感音性聴力喪失の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021530227A JP2021530227A (ja) | 2021-11-11 |
| JP2021530227A5 true JP2021530227A5 (https=) | 2022-07-20 |
| JPWO2020014625A5 JPWO2020014625A5 (https=) | 2022-07-20 |
Family
ID=69142651
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021500888A Pending JP2021530227A (ja) | 2018-07-13 | 2019-07-12 | 非症候性感音性聴力喪失の治療方法 |
| JP2024079983A Withdrawn JP2024109708A (ja) | 2018-07-13 | 2024-05-16 | 非症候性感音性聴力喪失の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024079983A Withdrawn JP2024109708A (ja) | 2018-07-13 | 2024-05-16 | 非症候性感音性聴力喪失の治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US12226493B2 (https=) |
| EP (1) | EP3821019A4 (https=) |
| JP (2) | JP2021530227A (https=) |
| CN (1) | CN112639108A (https=) |
| AU (1) | AU2019300045A1 (https=) |
| CA (1) | CA3106261A1 (https=) |
| WO (1) | WO2020014625A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020014625A1 (en) | 2018-07-13 | 2020-01-16 | Akouos, Inc. | Methods of treating non-syndromic sensorineural hearing loss |
| JP7846626B2 (ja) * | 2020-02-07 | 2026-04-15 | ザ チルドレンズ メディカル センター コーポレーション | 大型遺伝子ベクターならびにその送達および使用の方法 |
| US11946065B2 (en) * | 2020-07-29 | 2024-04-02 | The Board Of Regents Of The University Of Texas System | Transgene cassettes, AAV vectors, and AAV viral vectors for expression of human codon-optimized CSTB |
| JP2024517843A (ja) * | 2021-05-05 | 2024-04-23 | デシベル セラピューティクス インコーポレイテッド | ステレオシリン二重ベクター系を使用して感音性難聴を治療するための組成物及び方法 |
| IL308328A (en) * | 2021-05-14 | 2024-01-01 | Rescue Hearing Inc | Structures and methods of gene therapy to treat hearing loss |
| EP4416294A2 (en) * | 2021-10-12 | 2024-08-21 | Decibel Therapeutics, Inc. | Stereocilin promoters and uses thereof |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US5549910A (en) | 1989-03-31 | 1996-08-27 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
| US5252334A (en) | 1989-09-08 | 1993-10-12 | Cygnus Therapeutic Systems | Solid matrix system for transdermal drug delivery |
| JP3218637B2 (ja) | 1990-07-26 | 2001-10-15 | 大正製薬株式会社 | 安定なリポソーム水懸濁液 |
| JP2958076B2 (ja) | 1990-08-27 | 1999-10-06 | 株式会社ビタミン研究所 | 遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法 |
| US5795587A (en) | 1995-01-23 | 1998-08-18 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
| US5697899A (en) | 1995-02-07 | 1997-12-16 | Gensia | Feedback controlled drug delivery system |
| US5738868A (en) | 1995-07-18 | 1998-04-14 | Lipogenics Ltd. | Liposome compositions and kits therefor |
| US5656016A (en) | 1996-03-18 | 1997-08-12 | Abbott Laboratories | Sonophoretic drug delivery system |
| US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
| US5783208A (en) | 1996-07-19 | 1998-07-21 | Theratech, Inc. | Transdermal drug delivery matrix for coadministering estradiol and another steroid |
| US5779708A (en) | 1996-08-15 | 1998-07-14 | Cyberdent, Inc. | Intraosseous drug delivery device and method |
| CA2553676A1 (en) | 2004-01-28 | 2005-08-11 | Research Development Foundation | Human soluble neuropilin-1 primary polyadenylation signal and uses thereof |
| US20060040354A1 (en) | 2004-07-20 | 2006-02-23 | O'keefe Theresa L | Novel polyadenylation signal for use in expression vectors |
| CA2909733C (en) * | 2013-04-18 | 2023-10-17 | Fondazione Telethon | Effective delivery of large genes by dual aav vectors |
| WO2015048577A2 (en) * | 2013-09-27 | 2015-04-02 | Editas Medicine, Inc. | Crispr-related methods and compositions |
| SG11201804814YA (en) | 2015-12-11 | 2018-07-30 | Massachusetts Eye & Ear Infirmary | Materials and methods for delivering nucleic acids to cochlear and vestibular cells |
| JP2019530737A (ja) * | 2016-08-23 | 2019-10-24 | アコーオス インコーポレイテッド | ヒト対象において非加齢性聴力障害を治療するための組成物および方法 |
| WO2020014625A1 (en) | 2018-07-13 | 2020-01-16 | Akouos, Inc. | Methods of treating non-syndromic sensorineural hearing loss |
| EP4054653A4 (en) | 2019-11-04 | 2023-11-29 | Decibel Therapeutics, Inc. | PROMOTERS OF COCHLEAR EXTERNAL HAIR CELLS AND THEIR USES |
| JP7846626B2 (ja) | 2020-02-07 | 2026-04-15 | ザ チルドレンズ メディカル センター コーポレーション | 大型遺伝子ベクターならびにその送達および使用の方法 |
| US20240016955A1 (en) | 2020-09-14 | 2024-01-18 | President And Fellows Of Harvard College | Dual-aav vector delivery of pcdh15 and uses thereof |
| JP2024517843A (ja) | 2021-05-05 | 2024-04-23 | デシベル セラピューティクス インコーポレイテッド | ステレオシリン二重ベクター系を使用して感音性難聴を治療するための組成物及び方法 |
| IL308328A (en) | 2021-05-14 | 2024-01-01 | Rescue Hearing Inc | Structures and methods of gene therapy to treat hearing loss |
| EP4416294A2 (en) | 2021-10-12 | 2024-08-21 | Decibel Therapeutics, Inc. | Stereocilin promoters and uses thereof |
| JP2025504263A (ja) | 2021-12-23 | 2025-02-10 | ユニバーシティ オブ ロチェスター | 内耳への薬剤の送達のためのｃｓｆ輸送経路 |
| WO2024151703A2 (en) | 2023-01-12 | 2024-07-18 | Ohio State Innovation Foundation | Gene therapy for treating hearing loss disorders |
-
2019
- 2019-07-12 WO PCT/US2019/041625 patent/WO2020014625A1/en not_active Ceased
- 2019-07-12 CA CA3106261A patent/CA3106261A1/en active Pending
- 2019-07-12 AU AU2019300045A patent/AU2019300045A1/en not_active Abandoned
- 2019-07-12 US US17/259,661 patent/US12226493B2/en active Active
- 2019-07-12 EP EP19833536.6A patent/EP3821019A4/en active Pending
- 2019-07-12 JP JP2021500888A patent/JP2021530227A/ja active Pending
- 2019-07-12 CN CN201980057626.7A patent/CN112639108A/zh active Pending
-
2024
- 2024-05-16 JP JP2024079983A patent/JP2024109708A/ja not_active Withdrawn
-
2025
- 2025-01-09 US US19/015,387 patent/US20260000787A1/en active Pending
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