CN112639108A - 治疗非综合征性感觉神经性听力损失的方法 - Google Patents

治疗非综合征性感觉神经性听力损失的方法 Download PDF

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CN112639108A
CN112639108A CN201980057626.7A CN201980057626A CN112639108A CN 112639108 A CN112639108 A CN 112639108A CN 201980057626 A CN201980057626 A CN 201980057626A CN 112639108 A CN112639108 A CN 112639108A
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nucleotides
amino acids
amino acid
acid substitutions
amino
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E.J.西蒙斯
R.恩格
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Akus Co ltd
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CN201980057626.7A 2018-07-13 2019-07-12 治疗非综合征性感觉神经性听力损失的方法 Pending CN112639108A (zh)

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US201862697652P 2018-07-13 2018-07-13
US62/697,652 2018-07-13
PCT/US2019/041625 WO2020014625A1 (en) 2018-07-13 2019-07-12 Methods of treating non-syndromic sensorineural hearing loss

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US (2) US12226493B2 (https=)
EP (1) EP3821019A4 (https=)
JP (2) JP2021530227A (https=)
CN (1) CN112639108A (https=)
AU (1) AU2019300045A1 (https=)
CA (1) CA3106261A1 (https=)
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WO2020014625A1 (en) 2018-07-13 2020-01-16 Akouos, Inc. Methods of treating non-syndromic sensorineural hearing loss
JP7846626B2 (ja) * 2020-02-07 2026-04-15 ザ チルドレンズ メディカル センター コーポレーション 大型遺伝子ベクターならびにその送達および使用の方法
US11946065B2 (en) * 2020-07-29 2024-04-02 The Board Of Regents Of The University Of Texas System Transgene cassettes, AAV vectors, and AAV viral vectors for expression of human codon-optimized CSTB
JP2024517843A (ja) * 2021-05-05 2024-04-23 デシベル セラピューティクス インコーポレイテッド ステレオシリン二重ベクター系を使用して感音性難聴を治療するための組成物及び方法
IL308328A (en) * 2021-05-14 2024-01-01 Rescue Hearing Inc Structures and methods of gene therapy to treat hearing loss
EP4416294A2 (en) * 2021-10-12 2024-08-21 Decibel Therapeutics, Inc. Stereocilin promoters and uses thereof

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US12226493B2 (en) 2025-02-18
CA3106261A1 (en) 2020-01-16
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US20260000787A1 (en) 2026-01-01
US20210330814A1 (en) 2021-10-28
EP3821019A4 (en) 2022-10-05
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JP2024109708A (ja) 2024-08-14
WO2020014625A1 (en) 2020-01-16

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