CY1111499T1 - Συνθεσεις και μεθοδοι για τη θεραπευτικη χρηση μιας συνδεομενης με atonal αλληλουχιας - Google Patents

Συνθεσεις και μεθοδοι για τη θεραπευτικη χρηση μιας συνδεομενης με atonal αλληλουχιας

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Publication number
CY1111499T1
CY1111499T1 CY20111100232T CY111100232T CY1111499T1 CY 1111499 T1 CY1111499 T1 CY 1111499T1 CY 20111100232 T CY20111100232 T CY 20111100232T CY 111100232 T CY111100232 T CY 111100232T CY 1111499 T1 CY1111499 T1 CY 1111499T1
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Cyprus
Prior art keywords
atonal
nucleic acid
compositions
methods
sequence
Prior art date
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CY20111100232T
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English (en)
Inventor
Huda Y Zoghbi
Hugo Bellen
Nessan Birmingham
Bassem Hassan
Nissim Ben-Arie
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Baylor College Of Medicine
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Publication date
Application filed by Baylor College Of Medicine filed Critical Baylor College Of Medicine
Publication of CY1111499T1 publication Critical patent/CY1111499T1/el

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    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
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Abstract

Εδώ περιγράφονται συνθέσεις και μέθοδοι για τη θεραπευτική χρήση μιας συνδεόμενης με atonal αλληλουχίας νουκλεϊκών οξέων ή αμινοξέων. Επίσης περιγράφεται ένα ζώο ετερόζυγο για μια απενεργοποίηση συνδεόμενου με atonal γονιδίου που έχει τουλάχιστον μία συνδεόμενη με atonal αλληλουχία νουκλεϊκών οξέων αντικατεστημένη με ένθεση μιας ετερόλογης αλληλουχίας νουκλεϊκών οξέων η οποία χρησιμοποιείται για την ανίχνευση της έκφρασης που ωθείται από μια συνδεόμενη με atonal αλληλουχία προαγωγέα, όπου η απενεργοποίηση της συνδεόμενης με atonal αλληλουχίας νουκλεϊκών οξέων παρεμποδίζει την έκφραση του συνδεόμενου με atonal νουκλεϊκού οξέος.
CY20111100232T 1999-06-01 2011-02-28 Συνθεσεις και μεθοδοι για τη θεραπευτικη χρηση μιας συνδεομενης με atonal αλληλουχιας CY1111499T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13706099P 1999-06-01 1999-06-01
US17699300P 2000-01-19 2000-01-19
EP00941220A EP1471926B8 (en) 1999-06-01 2000-06-01 Compositions and methods for the therapeutic use of an atonal-associated sequence

Publications (1)

Publication Number Publication Date
CY1111499T1 true CY1111499T1 (el) 2015-08-05

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US (3) US6838444B1 (el)
EP (2) EP2325198A1 (el)
JP (4) JP2003530817A (el)
AT (1) ATE490777T1 (el)
AU (1) AU781802B2 (el)
CA (1) CA2375106C (el)
CY (1) CY1111499T1 (el)
DE (1) DE60045350D1 (el)
DK (1) DK1471926T3 (el)
PT (1) PT1471926E (el)
WO (1) WO2000073764A2 (el)

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CA2375106C (en) 2014-08-19
US20040237127A1 (en) 2004-11-25
WO2000073764A3 (en) 2004-05-27
US7470673B2 (en) 2008-12-30
US6838444B1 (en) 2005-01-04
AU5595900A (en) 2000-12-18
PT1471926E (pt) 2011-03-11
AU781802B2 (en) 2005-06-16
DE60045350D1 (de) 2011-01-20
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EP1471926A4 (en) 2004-11-03
US7442688B2 (en) 2008-10-28
ATE490777T1 (de) 2010-12-15
EP2325198A1 (en) 2011-05-25
DK1471926T3 (da) 2011-02-28
EP1471926A2 (en) 2004-11-03
US20040231009A1 (en) 2004-11-18
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