JP2003530088A5 - - Google Patents
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- Publication number
- JP2003530088A5 JP2003530088A5 JP2001562559A JP2001562559A JP2003530088A5 JP 2003530088 A5 JP2003530088 A5 JP 2003530088A5 JP 2001562559 A JP2001562559 A JP 2001562559A JP 2001562559 A JP2001562559 A JP 2001562559A JP 2003530088 A5 JP2003530088 A5 JP 2003530088A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- casb7439
- pharmaceutical composition
- immunogenic composition
- immunogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002163 immunogen Effects 0.000 description 10
- 239000000203 mixture Substances 0.000 description 10
- 239000008194 pharmaceutical composition Substances 0.000 description 8
- 229920001184 polypeptide Polymers 0.000 description 7
- 102000004196 processed proteins & peptides Human genes 0.000 description 7
- 108090000765 processed proteins & peptides Proteins 0.000 description 7
- 239000012634 fragment Substances 0.000 description 6
- 239000002671 adjuvant Substances 0.000 description 5
- 108091033319 polynucleotide Proteins 0.000 description 5
- 102000040430 polynucleotide Human genes 0.000 description 5
- 239000002157 polynucleotide Substances 0.000 description 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 4
- 125000003275 alpha amino acid group Chemical group 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
- 201000011510 cancer Diseases 0.000 description 3
- 239000003937 drug carrier Substances 0.000 description 3
- 210000000612 antigen-presenting cell Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 206010009944 Colon cancer Diseases 0.000 description 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009169 immunotherapy Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0004269A GB0004269D0 (en) | 2000-02-23 | 2000-02-23 | Novel compounds |
| GB0004269.7 | 2000-02-23 | ||
| GB0009905A GB0009905D0 (en) | 2000-04-20 | 2000-04-20 | Novel compounds |
| GB0009905.1 | 2000-04-20 | ||
| GB0021080A GB0021080D0 (en) | 2000-08-25 | 2000-08-25 | Novel compounds |
| GB0021080.7 | 2000-08-25 | ||
| PCT/EP2001/001779 WO2001062778A2 (en) | 2000-02-23 | 2001-02-16 | Tumour-specific animal proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003530088A JP2003530088A (ja) | 2003-10-14 |
| JP2003530088A5 true JP2003530088A5 (enExample) | 2008-03-27 |
| JP5502253B2 JP5502253B2 (ja) | 2014-05-28 |
Family
ID=27255552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001562559A Expired - Fee Related JP5502253B2 (ja) | 2000-02-23 | 2001-02-16 | 新規化合物 |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US20030157118A1 (enExample) |
| EP (2) | EP1265915B1 (enExample) |
| JP (1) | JP5502253B2 (enExample) |
| KR (3) | KR20090085697A (enExample) |
| CN (1) | CN1254541C (enExample) |
| AT (1) | ATE487733T1 (enExample) |
| AU (3) | AU5615601A (enExample) |
| BR (1) | BR0108654A (enExample) |
| CA (1) | CA2400842C (enExample) |
| CY (2) | CY1111156T1 (enExample) |
| CZ (1) | CZ303468B6 (enExample) |
| DE (1) | DE60143425D1 (enExample) |
| DK (2) | DK1265915T3 (enExample) |
| ES (1) | ES2389445T3 (enExample) |
| HU (1) | HUP0300054A3 (enExample) |
| IL (2) | IL151097A0 (enExample) |
| MX (1) | MXPA02008279A (enExample) |
| NO (1) | NO332141B1 (enExample) |
| NZ (1) | NZ520673A (enExample) |
| PL (1) | PL209127B1 (enExample) |
| PT (2) | PT1265915E (enExample) |
| SI (2) | SI1265915T1 (enExample) |
| WO (1) | WO2001062778A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60143425D1 (de) * | 2000-02-23 | 2010-12-23 | Smithkline Beecham Biolog | Neue verbindungen |
| DK2266603T3 (da) * | 2000-10-18 | 2012-11-05 | Glaxosmithkline Biolog Sa | Tumorvacciner |
| US8039602B2 (en) | 2000-10-31 | 2011-10-18 | Ryogen Llc | Isolated genomic polynucleotide fragments from the p15 region of chromosome 11 |
| GB0100756D0 (en) | 2001-01-11 | 2001-02-21 | Powderject Res Ltd | Needleless syringe |
| GB0111974D0 (en) * | 2001-05-16 | 2001-07-04 | Glaxosmithkline Biolog Sa | Novel Compounds |
| JP2006512901A (ja) * | 2002-08-29 | 2006-04-20 | ジェネンテック・インコーポレーテッド | Ａｃｈａｅｔｅ−Ｓｃｕｔｅ様−２ポリペプチドとそのコード化核酸並びに腫瘍の診断と治療のための方法 |
| CN1310033C (zh) * | 2004-03-23 | 2007-04-11 | 中国医学科学院肿瘤医院肿瘤研究所 | 一种检测血清蛋白指纹的新方法 |
| EP2390360A1 (en) | 2006-06-02 | 2011-11-30 | GlaxoSmithKline Biologicals S.A. | Method for identifying whether a patient will be responder or not to immunotherapy based on the differential expression of the IDO1 gene |
| GB0708758D0 (en) | 2007-05-04 | 2007-06-13 | Powderject Res Ltd | Particle cassettes and process thereof |
| CA2687632C (en) | 2007-05-24 | 2013-01-15 | Glaxosmithkline Biologicals S.A. | Lyophilised antigen composition |
| BRPI1012078A2 (pt) * | 2009-05-27 | 2019-09-24 | Glaxosmithkline Biologicals Sa | construto de proteína, composição imunogênica, molécula de ácido nucleico , métodos de induzir uma resposta imune a casb7439 e de tratar um animal humano ou não-humano, e, uso de uma composição imunogênica |
| GB0917457D0 (en) | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
| US20110129574A1 (en) * | 2009-11-30 | 2011-06-02 | Pathak Chandrashekhar P | Methods and compositions for filling fleshy fruits and vegetables |
| TR201808733T4 (tr) * | 2011-10-03 | 2018-07-23 | Mx Adjuvac Ab | Kanser tedavisini ve gıda ile ilgili bileşikleri içeren tıp alanlarında amfipatik veya hidrofobik moleküller için taşıyıcı olarak nano-parçacıklar, preparasyon için proses ve bunların kullanımı. |
| WO2016146143A1 (en) | 2015-03-16 | 2016-09-22 | Amal Therapeutics Sa | Cell penetrating peptides and complexes comprising the same |
| GB201520592D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| LT3429618T (lt) | 2016-03-16 | 2024-05-10 | Amal Therapeutics Sa | Imuninės sistemos patikros taško moduliatoriaus ir komplekso, apimančio į ląsteles prasiskverbiantį peptidą, krovinį ir tlr peptido agonistą, derinys, skirtas naudoti medicinoje |
| WO2018055060A1 (en) * | 2016-09-21 | 2018-03-29 | Amal Therapeutics Sa | Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer |
| US10422675B2 (en) | 2017-06-09 | 2019-09-24 | Aps Technology, Inc. | System and method for monitoring mud flow in a component of drilling system |
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| DE60143425D1 (de) * | 2000-02-23 | 2010-12-23 | Smithkline Beecham Biolog | Neue verbindungen |
| US7811574B2 (en) * | 2000-02-23 | 2010-10-12 | Glaxosmithkline Biologicals S.A. | Tumour-specific animal proteins |
| US8039602B2 (en) * | 2000-10-31 | 2011-10-18 | Ryogen Llc | Isolated genomic polynucleotide fragments from the p15 region of chromosome 11 |
| JP2006512901A (ja) | 2002-08-29 | 2006-04-20 | ジェネンテック・インコーポレーテッド | Ａｃｈａｅｔｅ−Ｓｃｕｔｅ様−２ポリペプチドとそのコード化核酸並びに腫瘍の診断と治療のための方法 |
| BRPI1012078A2 (pt) | 2009-05-27 | 2019-09-24 | Glaxosmithkline Biologicals Sa | construto de proteína, composição imunogênica, molécula de ácido nucleico , métodos de induzir uma resposta imune a casb7439 e de tratar um animal humano ou não-humano, e, uso de uma composição imunogênica |
-
2001
- 2001-02-16 DE DE60143425T patent/DE60143425D1/de not_active Expired - Lifetime
- 2001-02-16 KR KR1020097013427A patent/KR20090085697A/ko not_active Ceased
- 2001-02-16 KR KR1020027010961A patent/KR100848973B1/ko not_active Expired - Fee Related
- 2001-02-16 MX MXPA02008279A patent/MXPA02008279A/es active IP Right Grant
- 2001-02-16 AT AT01929345T patent/ATE487733T1/de active
- 2001-02-16 EP EP01929345A patent/EP1265915B1/en not_active Expired - Lifetime
- 2001-02-16 DK DK01929345.5T patent/DK1265915T3/da active
- 2001-02-16 AU AU5615601A patent/AU5615601A/xx active Pending
- 2001-02-16 BR BR0108654-5A patent/BR0108654A/pt not_active IP Right Cessation
- 2001-02-16 PT PT01929345T patent/PT1265915E/pt unknown
- 2001-02-16 CA CA2400842A patent/CA2400842C/en not_active Expired - Fee Related
- 2001-02-16 WO PCT/EP2001/001779 patent/WO2001062778A2/en not_active Ceased
- 2001-02-16 SI SI200130986T patent/SI1265915T1/sl unknown
- 2001-02-16 SI SI200131014T patent/SI1650221T1/sl unknown
- 2001-02-16 JP JP2001562559A patent/JP5502253B2/ja not_active Expired - Fee Related
- 2001-02-16 AU AU2001256156A patent/AU2001256156B2/en not_active Ceased
- 2001-02-16 CZ CZ20022874A patent/CZ303468B6/cs not_active IP Right Cessation
- 2001-02-16 PT PT06075141T patent/PT1650221E/pt unknown
- 2001-02-16 CN CNB018084117A patent/CN1254541C/zh not_active Expired - Fee Related
- 2001-02-16 DK DK06075141.9T patent/DK1650221T3/da active
- 2001-02-16 IL IL15109701A patent/IL151097A0/xx unknown
- 2001-02-16 KR KR1020087004445A patent/KR100919916B1/ko not_active Expired - Fee Related
- 2001-02-16 NZ NZ520673A patent/NZ520673A/en not_active IP Right Cessation
- 2001-02-16 PL PL362698A patent/PL209127B1/pl unknown
- 2001-02-16 ES ES06075141T patent/ES2389445T3/es not_active Expired - Lifetime
- 2001-02-16 EP EP06075141A patent/EP1650221B1/en not_active Expired - Lifetime
- 2001-02-16 HU HU0300054A patent/HUP0300054A3/hu unknown
-
2002
- 2002-08-06 IL IL151097A patent/IL151097A/en not_active IP Right Cessation
- 2002-08-22 NO NO20024002A patent/NO332141B1/no not_active IP Right Cessation
- 2002-08-23 US US10/226,872 patent/US20030157118A1/en not_active Abandoned
-
2005
- 2005-12-13 US US11/301,895 patent/US7803379B2/en not_active Expired - Fee Related
-
2006
- 2006-03-10 AU AU2006201042A patent/AU2006201042B2/en not_active Ceased
-
2009
- 2009-03-09 US US12/400,449 patent/US20100291121A1/en not_active Abandoned
-
2010
- 2010-08-20 US US12/860,020 patent/US8207123B2/en not_active Expired - Fee Related
-
2011
- 2011-01-28 CY CY20111100086T patent/CY1111156T1/el unknown
-
2012
- 2012-05-15 US US13/472,035 patent/US8535690B2/en not_active Expired - Fee Related
- 2012-09-12 CY CY20121100829T patent/CY1113109T1/el unknown
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