JP2006020648A5 - - Google Patents
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- JP2006020648A5 JP2006020648A5 JP2005271209A JP2005271209A JP2006020648A5 JP 2006020648 A5 JP2006020648 A5 JP 2006020648A5 JP 2005271209 A JP2005271209 A JP 2005271209A JP 2005271209 A JP2005271209 A JP 2005271209A JP 2006020648 A5 JP2006020648 A5 JP 2006020648A5
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- JP
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- Prior art keywords
- trt
- polypeptide
- antigen
- leukocytes
- consecutive amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 229920001184 polypeptide Polymers 0.000 claims 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims 11
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 claims 8
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 6
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 5
- 210000000265 leukocyte Anatomy 0.000 claims 3
- 101000655352 Homo sapiens Telomerase reverse transcriptase Proteins 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 2
- 102000043129 MHC class I family Human genes 0.000 claims 1
- 108091054437 MHC class I family Proteins 0.000 claims 1
- 102000043131 MHC class II family Human genes 0.000 claims 1
- 108091054438 MHC class II family Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 108010017842 Telomerase Proteins 0.000 claims 1
- 102100032938 Telomerase reverse transcriptase Human genes 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 210000002433 mononuclear leukocyte Anatomy 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11200698P | 1998-03-31 | 1998-03-31 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000541280A Division JP2002509716A (ja) | 1998-03-31 | 1999-03-30 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006353532A Division JP2007137889A (ja) | 1998-03-31 | 2006-12-27 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006020648A JP2006020648A (ja) | 2006-01-26 |
| JP2006020648A5 true JP2006020648A5 (enExample) | 2007-02-15 |
Family
ID=22341634
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000541280A Withdrawn JP2002509716A (ja) | 1998-03-31 | 1999-03-30 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
| JP2005271209A Withdrawn JP2006020648A (ja) | 1998-03-31 | 2005-09-16 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
| JP2006353532A Pending JP2007137889A (ja) | 1998-03-31 | 2006-12-27 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000541280A Withdrawn JP2002509716A (ja) | 1998-03-31 | 1999-03-30 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006353532A Pending JP2007137889A (ja) | 1998-03-31 | 2006-12-27 | テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6440735B1 (enExample) |
| EP (1) | EP1068296B1 (enExample) |
| JP (3) | JP2002509716A (enExample) |
| AU (1) | AU3456099A (enExample) |
| CA (1) | CA2347067C (enExample) |
| WO (1) | WO1999050392A1 (enExample) |
Families Citing this family (61)
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| US6444650B1 (en) * | 1996-10-01 | 2002-09-03 | Geron Corporation | Antisense compositions for detecting and inhibiting telomerase reverse transcriptase |
| US6475789B1 (en) * | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
| US6093809A (en) * | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
| US20050013825A1 (en) * | 1997-04-18 | 2005-01-20 | Geron Corporation | Vaccine containing the catalytic subunit of telomerase for treating cancer |
| US7413864B2 (en) * | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
| US7622549B2 (en) * | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
| US7402307B2 (en) | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
| US6337200B1 (en) * | 1998-03-31 | 2002-01-08 | Geron Corporation | Human telomerase catalytic subunit variants |
| CA2347067C (en) | 1998-03-31 | 2013-09-17 | Geron Corporation | Dendritic cell vaccine containing telomerase reverse transcriptase for the treatment of cancer |
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| US20020142974A1 (en) * | 1998-09-11 | 2002-10-03 | Leonard D. Kohn | Immune activation by double-stranded polynucleotides |
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| EP1257284A4 (en) * | 2000-02-15 | 2005-12-21 | Univ California | UNIVERSAL VACCINE AND METHOD OF TREATING CANCER USING TELOMERASE REVERSE TRANSCRIPTASE |
| JP2004527449A (ja) | 2000-02-15 | 2004-09-09 | リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | テロメラーゼ逆転写酵素を用いる癌を治療するための万能ワクチンと方法 |
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| PT1592441E (pt) * | 2003-02-06 | 2012-05-21 | Aduro Biotech | Listeria atenuada relativamente à entrada em células não patogénicas, vacinas compreendendo a listeria e métodos para sua utilização |
| US7695725B2 (en) * | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| WO2004084936A2 (en) * | 2003-02-06 | 2004-10-07 | Cerus Corporation | Modified free-living microbes, vaccine compositions and methods of use thereof |
| US7842289B2 (en) * | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| US20090053249A1 (en) | 2004-07-20 | 2009-02-26 | Yan Qi | Specific Inhibition of Autoimmunity and Diseases Associated With Autoantigens |
| CA2504451A1 (en) * | 2004-08-10 | 2006-02-10 | Geron Corporation | Dendritic cell vaccines for treating cancer made from embryonic stem cells |
| JPWO2006025526A1 (ja) * | 2004-09-03 | 2008-05-08 | 株式会社医学生物学研究所 | Ｃｔｌ誘導能を獲得した樹状細胞の製造方法 |
| JPWO2006025525A1 (ja) * | 2004-09-03 | 2008-05-08 | 株式会社医学生物学研究所 | 樹状細胞において抗原提示されやすいタンパク質の選択方法 |
| US20090196850A1 (en) | 2005-01-06 | 2009-08-06 | Novo Nordisk A/S | Anti-Kir Combination Treatments and Methods |
| EA015584B1 (ru) | 2005-03-23 | 2011-10-31 | Генмаб А/С | Антитело к cd38 человека и его применение |
| EP1748067A1 (en) * | 2005-07-29 | 2007-01-31 | Institut Pasteur | Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes |
| RU2309753C1 (ru) * | 2006-05-05 | 2007-11-10 | ЗАО "РеМеТэкс" | Комбинированный клеточный трансплантат на основе лимфокинактивированных киллеров и дендритных клеток, способ его получения и способ лечения и профилактики онкологических, инфекционных заболеваний и иммунодефицитных состояний |
| HRP20191115T1 (hr) | 2006-09-26 | 2019-09-20 | Genmab A/S | Anti-cd38 u kombinaciji s kortikosteroidima zajedno s jednim ne-kortikosteroidnim kemoterapeutikom za liječenje tumora |
| UA109633C2 (uk) | 2008-12-09 | 2015-09-25 | Антитіло людини проти тканинного фактора | |
| WO2010096693A2 (en) * | 2009-02-19 | 2010-08-26 | Mayo Foundation For Medical Education And Research | Methods and materials for generating t cells |
| US8563307B2 (en) | 2009-02-24 | 2013-10-22 | James Wang | Treatment of immunosuppression-related disorders |
| US9657068B2 (en) | 2010-02-16 | 2017-05-23 | Ultimovacs As | Telomerase polypeptide vaccine for treating cancer |
| RS66008B1 (sr) | 2010-03-10 | 2024-10-31 | Genmab As | Monoklonska antitela protiv c-met |
| EP2575880B1 (en) | 2010-05-27 | 2019-01-16 | Genmab A/S | Monoclonal antibodies against her2 epitope |
| CA3051311A1 (en) | 2010-05-27 | 2011-12-01 | Genmab A/S | Monoclonal antibodies against her2 |
| EP2580243B1 (en) | 2010-06-09 | 2019-10-16 | Genmab A/S | Antibodies against human cd38 |
| SMT201700547T1 (it) | 2010-06-15 | 2018-01-11 | Genmab As | Coniugati di farmaco anticorpo umano contro il fattore tissutale |
| US8679474B2 (en) | 2010-08-04 | 2014-03-25 | StemBios Technologies, Inc. | Somatic stem cells |
| JP6177231B2 (ja) | 2011-04-20 | 2017-08-09 | ゲンマブ エー／エス | Ｈｅｒ２に対する二重特異性抗体 |
| EP4520771A3 (en) | 2011-04-20 | 2025-07-16 | Genmab A/S | Bispecifc antibodies against her2 |
| JP2014514314A (ja) | 2011-04-20 | 2014-06-19 | ゲンマブ エー／エス | Ｈｅｒ２およびｃｄ３に対する二重特異性抗体 |
| TWI614340B (zh) | 2011-09-28 | 2018-02-11 | 幹細胞生物科技股份有限公司 | 體幹細胞及其製備方法 |
| CN104822827B (zh) | 2012-12-06 | 2020-01-21 | 干细胞生物科技公司 | Lgr5+体干细胞 |
| EP2746770A1 (en) | 2012-12-21 | 2014-06-25 | Stembios Technologies, Inc. | Method for evaluating effect of action on subject based on stem celldynamics |
| US20170058043A1 (en) | 2014-12-06 | 2017-03-02 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Bispecific antibody for cancer immunotherapy |
| WO2017152008A1 (en) | 2016-03-04 | 2017-09-08 | The Trustees Of Columbia University In The City Of New York | Development of dual whole cell-based vaccine against pancreatic cancer |
| US20190167722A1 (en) * | 2016-08-02 | 2019-06-06 | Nant Holdings Ip, Llc | Transfection of dendritic cells and methods therefor |
| US11464841B2 (en) * | 2016-09-30 | 2022-10-11 | The Trustees Of The University Of Pennsylvania | TERT immunogenic compositions and methods of treatment using the same |
| WO2018156434A1 (en) | 2017-02-22 | 2018-08-30 | H. Lee Moffitt Cancer Center And Research Institute Inc. | Tim3-binding chimeric antigen receptors |
| MX2019015484A (es) | 2017-07-07 | 2020-07-28 | H Lee Moffitt Cancer Ct & Res | Receptores quiméricos de antígeno con dominios coestimuladores cd28 mutados. |
| CN112040957A (zh) | 2018-01-08 | 2020-12-04 | H·李·莫菲特癌症中心和研究所公司 | 靶向表达cd99的癌症的组合物和方法 |
| WO2019139888A1 (en) | 2018-01-09 | 2019-07-18 | H. Lee Moffitt Cancer Center And Research Institute Inc. | Compositions and methods for targeting clec12a-expressing cancers |
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| EP4110319A4 (en) | 2020-02-27 | 2024-02-14 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | TUMOR-INFILTING LYMPHOCYTES WITH INCREASED TUMOR REACTIVITY |
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| WO2024206155A1 (en) | 2023-03-24 | 2024-10-03 | Cornell University | Utilizing t cells derived from tumor draining lymph nodes for chimeric antigen receptor (car) t cell therapy for the treatment of cancer |
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| ATE347904T1 (de) | 1998-10-29 | 2007-01-15 | Dana Farber Cancer Inst Inc | Krebsimmuntherapie und krebsdiagnose unter verwendung universeller tumorassoziierter antigene einschliesslich htert |
| GB9824306D0 (en) | 1998-11-05 | 1998-12-30 | Isis Innovation | Method for producing dendritic dells |
| EP1171612A2 (en) * | 1999-04-09 | 2002-01-16 | Biomira, Inc. | Telomerase-specific cancer vaccine |
-
1999
- 1999-03-30 CA CA2347067A patent/CA2347067C/en not_active Expired - Lifetime
- 1999-03-30 WO PCT/US1999/006898 patent/WO1999050392A1/en not_active Ceased
- 1999-03-30 EP EP99916193A patent/EP1068296B1/en not_active Expired - Lifetime
- 1999-03-30 JP JP2000541280A patent/JP2002509716A/ja not_active Withdrawn
- 1999-03-30 AU AU34560/99A patent/AU3456099A/en not_active Abandoned
-
2000
- 2000-09-29 US US09/675,321 patent/US6440735B1/en not_active Expired - Lifetime
-
2005
- 2005-09-16 JP JP2005271209A patent/JP2006020648A/ja not_active Withdrawn
-
2006
- 2006-12-27 JP JP2006353532A patent/JP2007137889A/ja active Pending
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