AU3456099A - Methods and compositions for eliciting an immune response to a telomerase antigen - Google Patents
Methods and compositions for eliciting an immune response to a telomerase antigenInfo
- Publication number
- AU3456099A AU3456099A AU34560/99A AU3456099A AU3456099A AU 3456099 A AU3456099 A AU 3456099A AU 34560/99 A AU34560/99 A AU 34560/99A AU 3456099 A AU3456099 A AU 3456099A AU 3456099 A AU3456099 A AU 3456099A
- Authority
- AU
- Australia
- Prior art keywords
- eliciting
- compositions
- methods
- immune response
- telomerase antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108010017842 Telomerase Proteins 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4244—Enzymes
- A61K40/4246—Telomerase or [telomerase reverse transcriptase [TERT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11200698P | 1998-03-31 | 1998-03-31 | |
| US60112006 | 1998-03-31 | ||
| PCT/US1999/006898 WO1999050392A1 (en) | 1998-03-31 | 1999-03-30 | Methods and compositions for eliciting an immune response to a telomerase antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU3456099A true AU3456099A (en) | 1999-10-18 |
Family
ID=22341634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU34560/99A Abandoned AU3456099A (en) | 1998-03-31 | 1999-03-30 | Methods and compositions for eliciting an immune response to a telomerase antigen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6440735B1 (enExample) |
| EP (1) | EP1068296B1 (enExample) |
| JP (3) | JP2002509716A (enExample) |
| AU (1) | AU3456099A (enExample) |
| CA (1) | CA2347067C (enExample) |
| WO (1) | WO1999050392A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU781376B2 (en) * | 1999-04-09 | 2005-05-19 | Biomira Inc. | Telomerase-specific cancer vaccine |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6261836B1 (en) * | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
| US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
| CN1254376A (zh) * | 1996-10-01 | 2000-05-24 | 杰龙公司 | 端粒酶逆转录酶 |
| US6444650B1 (en) * | 1996-10-01 | 2002-09-03 | Geron Corporation | Antisense compositions for detecting and inhibiting telomerase reverse transcriptase |
| US6093809A (en) * | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
| US6808880B2 (en) * | 1996-10-01 | 2004-10-26 | Geron Corporation | Method for detecting polynucleotides encoding telomerase |
| US6475789B1 (en) * | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| US20050013825A1 (en) * | 1997-04-18 | 2005-01-20 | Geron Corporation | Vaccine containing the catalytic subunit of telomerase for treating cancer |
| US7413864B2 (en) * | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
| US7622549B2 (en) * | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
| US7402307B2 (en) | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
| WO1999050392A1 (en) | 1998-03-31 | 1999-10-07 | Geron Corporation | Methods and compositions for eliciting an immune response to a telomerase antigen |
| US6337200B1 (en) * | 1998-03-31 | 2002-01-08 | Geron Corporation | Human telomerase catalytic subunit variants |
| US7030211B1 (en) | 1998-07-08 | 2006-04-18 | Gemvax As | Antigenic peptides derived from telomerase |
| US20020142974A1 (en) * | 1998-09-11 | 2002-10-03 | Leonard D. Kohn | Immune activation by double-stranded polynucleotides |
| CA2344972A1 (en) * | 1998-10-29 | 2000-05-11 | Dana-Farber Cancer Institute, Inc. | Cancer immunotherapy and diagnosis using universal tumor associated antigens, including htert |
| EP1257284A4 (en) * | 2000-02-15 | 2005-12-21 | Univ California | UNIVERSAL VACCINE AND METHOD OF TREATING CANCER USING TELOMERASE REVERSE TRANSCRIPTASE |
| WO2001060391A1 (en) | 2000-02-15 | 2001-08-23 | Regents Of The University Of California | A universal vaccine and method for treating cancer employing telomerase reverse transcriptase |
| GB0031430D0 (en) * | 2000-12-22 | 2001-02-07 | Norsk Hydro As | Polypeptides |
| US7695725B2 (en) * | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| WO2004084936A2 (en) * | 2003-02-06 | 2004-10-07 | Cerus Corporation | Modified free-living microbes, vaccine compositions and methods of use thereof |
| DK1592441T3 (da) * | 2003-02-06 | 2012-05-14 | Aduro Biotech | Listeria, hvis indtrængen i ikke-phagocytiske celler er svækket, vacciner omfattende listeria og fremgangsmåder til anvendelse deraf |
| US7842289B2 (en) * | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| JP2008507282A (ja) | 2004-07-20 | 2008-03-13 | アイソジェニス・インコーポレイテッド | 自己免疫および自己抗原に関連する疾患の特異的阻害 |
| CA2504451A1 (en) * | 2004-08-10 | 2006-02-10 | Geron Corporation | Dendritic cell vaccines for treating cancer made from embryonic stem cells |
| WO2006025525A1 (ja) * | 2004-09-03 | 2006-03-09 | Medical And Biological Laboratories Co., Ltd. | 樹状細胞において抗原提示されやすいタンパク質の選択方法 |
| US20080194020A1 (en) * | 2004-09-03 | 2008-08-14 | Medical And Biological Laboratories Co., Ltd. | Methods For Producing Dendritic Cells That Have Acquired Ctl-Inducing Ability |
| WO2006072625A2 (en) | 2005-01-06 | 2006-07-13 | Novo Nordisk A/S | Anti-kir combination treatments and methods |
| EP3312196B1 (en) | 2005-03-23 | 2019-07-17 | Genmab A/S | Antibodies against cd38 for treatment of multiple myeloma |
| EP1748067A1 (en) * | 2005-07-29 | 2007-01-31 | Institut Pasteur | Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes |
| RU2309753C1 (ru) * | 2006-05-05 | 2007-11-10 | ЗАО "РеМеТэкс" | Комбинированный клеточный трансплантат на основе лимфокинактивированных киллеров и дендритных клеток, способ его получения и способ лечения и профилактики онкологических, инфекционных заболеваний и иммунодефицитных состояний |
| AU2007302448C1 (en) | 2006-09-26 | 2019-02-14 | Genmab A/S | Combination treatment of CD38-expressing tumors |
| UA109633C2 (uk) | 2008-12-09 | 2015-09-25 | Антитіло людини проти тканинного фактора | |
| WO2010096693A2 (en) * | 2009-02-19 | 2010-08-26 | Mayo Foundation For Medical Education And Research | Methods and materials for generating t cells |
| US8563307B2 (en) | 2009-02-24 | 2013-10-22 | James Wang | Treatment of immunosuppression-related disorders |
| EP3581649A1 (en) | 2010-02-16 | 2019-12-18 | Ultimovacs ASA | Polypeptides |
| WO2011110642A2 (en) | 2010-03-10 | 2011-09-15 | Genmab A/S | Monoclonal antibodies against c-met |
| CA3051311A1 (en) | 2010-05-27 | 2011-12-01 | Genmab A/S | Monoclonal antibodies against her2 |
| NZ604007A (en) | 2010-05-27 | 2015-03-27 | Genmab As | Monoclonal antibodies against her2 epitope |
| EP2580243B1 (en) | 2010-06-09 | 2019-10-16 | Genmab A/S | Antibodies against human cd38 |
| SMT201700547T1 (it) | 2010-06-15 | 2018-01-11 | Genmab As | Coniugati di farmaco anticorpo umano contro il fattore tissutale |
| US8679474B2 (en) * | 2010-08-04 | 2014-03-25 | StemBios Technologies, Inc. | Somatic stem cells |
| WO2012143523A1 (en) | 2011-04-20 | 2012-10-26 | Genmab A/S | Bispecifc antibodies against her2 |
| EP4520771A3 (en) | 2011-04-20 | 2025-07-16 | Genmab A/S | Bispecifc antibodies against her2 |
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| US11020465B2 (en) | 2016-03-04 | 2021-06-01 | The Trustees Of Columbia University In The City Of New York | Development of dual whole cell-based vaccine against pancreatic cancer |
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| BR112020000118A2 (pt) | 2017-07-07 | 2020-07-07 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | receptores de antígenos quiméricos com domínios coestimulatórios cd28 mutados |
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| EP4687959A1 (en) | 2023-03-24 | 2026-02-11 | Cornell University | Utilizing t cells derived from tumor draining lymph nodes for chimeric antigen receptor (car) t cell therapy for the treatment of cancer |
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-
1999
- 1999-03-30 WO PCT/US1999/006898 patent/WO1999050392A1/en not_active Ceased
- 1999-03-30 CA CA2347067A patent/CA2347067C/en not_active Expired - Lifetime
- 1999-03-30 EP EP99916193A patent/EP1068296B1/en not_active Expired - Lifetime
- 1999-03-30 AU AU34560/99A patent/AU3456099A/en not_active Abandoned
- 1999-03-30 JP JP2000541280A patent/JP2002509716A/ja not_active Withdrawn
-
2000
- 2000-09-29 US US09/675,321 patent/US6440735B1/en not_active Expired - Lifetime
-
2005
- 2005-09-16 JP JP2005271209A patent/JP2006020648A/ja not_active Withdrawn
-
2006
- 2006-12-27 JP JP2006353532A patent/JP2007137889A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU781376B2 (en) * | 1999-04-09 | 2005-05-19 | Biomira Inc. | Telomerase-specific cancer vaccine |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006020648A (ja) | 2006-01-26 |
| JP2007137889A (ja) | 2007-06-07 |
| CA2347067A1 (en) | 1999-10-07 |
| JP2002509716A (ja) | 2002-04-02 |
| US6440735B1 (en) | 2002-08-27 |
| EP1068296B1 (en) | 2011-08-10 |
| EP1068296A4 (en) | 2003-06-04 |
| WO1999050392A1 (en) | 1999-10-07 |
| CA2347067C (en) | 2013-09-17 |
| EP1068296A1 (en) | 2001-01-17 |
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