IT1264516B1 - Cellule dendritiche immortalizzate - Google Patents

Cellule dendritiche immortalizzate

Info

Publication number
IT1264516B1
IT1264516B1 IT93MI001118A ITMI931118A IT1264516B1 IT 1264516 B1 IT1264516 B1 IT 1264516B1 IT 93MI001118 A IT93MI001118 A IT 93MI001118A IT MI931118 A ITMI931118 A IT MI931118A IT 1264516 B1 IT1264516 B1 IT 1264516B1
Authority
IT
Italy
Prior art keywords
dendritic cells
immortalized dendritic
immortalized
vectors containing
retroviral vectors
Prior art date
Application number
IT93MI001118A
Other languages
English (en)
Inventor
Paola Paglia
Francesca Granucci
Original Assignee
Biotop Sas Di Rita Cassarin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotop Sas Di Rita Cassarin filed Critical Biotop Sas Di Rita Cassarin
Publication of ITMI931118A0 publication Critical patent/ITMI931118A0/it
Priority to IT93MI001118A priority Critical patent/IT1264516B1/it
Priority to US08/549,666 priority patent/US5856180A/en
Priority to AT94917670T priority patent/ATE173294T1/de
Priority to PCT/EP1994/001720 priority patent/WO1994028113A1/en
Priority to EP94917670A priority patent/EP0701604B1/en
Priority to DE69414572T priority patent/DE69414572T2/de
Priority to ES94917670T priority patent/ES2126118T3/es
Priority to JP50023195A priority patent/JP3834059B2/ja
Priority to KR1019950705371A priority patent/KR100353220B1/ko
Priority to HU9503414A priority patent/HUT73322A/hu
Priority to AU69299/94A priority patent/AU686636B2/en
Priority to CA002164102A priority patent/CA2164102A1/en
Priority to DK94917670T priority patent/DK0701604T3/da
Priority to ZA943782A priority patent/ZA943782B/xx
Publication of ITMI931118A1 publication Critical patent/ITMI931118A1/it
Application granted granted Critical
Publication of IT1264516B1 publication Critical patent/IT1264516B1/it
Priority to US09/002,380 priority patent/US6156307A/en
Priority to GR990400460T priority patent/GR3029374T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464452—Transcription factors, e.g. SOX or c-MYC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Cellule dendritiche sono state immortalizzate con vettori retrovirali contenenti l'oncogene v-myc.
IT93MI001118A 1993-05-31 1993-05-31 Cellule dendritiche immortalizzate IT1264516B1 (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT93MI001118A IT1264516B1 (it) 1993-05-31 1993-05-31 Cellule dendritiche immortalizzate
KR1019950705371A KR100353220B1 (ko) 1993-05-31 1994-05-26 V-myc종양형성유전자를이용한수상돌기세포의불멸화방법
AU69299/94A AU686636B2 (en) 1993-05-31 1994-05-26 Immortalization of denditric cells with V-MYC oncogene
PCT/EP1994/001720 WO1994028113A1 (en) 1993-05-31 1994-05-26 Immortalization of denditric cells with v-myc oncogene
EP94917670A EP0701604B1 (en) 1993-05-31 1994-05-26 Immortalization of denditric cells with v-myc oncogene
DE69414572T DE69414572T2 (de) 1993-05-31 1994-05-26 Immortalisierung von dendritischen zellen mit dem v-myc onkogen
ES94917670T ES2126118T3 (es) 1993-05-31 1994-05-26 Inmortalizacion de celulas dendriticas con el oncogen v-myc.
JP50023195A JP3834059B2 (ja) 1993-05-31 1994-05-26 ｖ−ｍｙｃ発癌遺伝子を用いる樹枝状細胞の固定
US08/549,666 US5856180A (en) 1993-05-31 1994-05-26 Immortalization of dendritic cells with V-MYC oncogene
HU9503414A HUT73322A (en) 1993-05-31 1994-05-26 Immortalization of denditric cells with v-myc oncogene
AT94917670T ATE173294T1 (de) 1993-05-31 1994-05-26 Immortalisierung von dendritischen zellen mit dem v-myc onkogen
CA002164102A CA2164102A1 (en) 1993-05-31 1994-05-26 Immortalization of denditric cells with v-myc oncogene
DK94917670T DK0701604T3 (da) 1993-05-31 1994-05-26 Immortalisering af dendritiske celler med V-myc-onkogenet
ZA943782A ZA943782B (en) 1993-05-31 1994-05-30 Immortalization of dendritic cells and generation of functional dendritic cell lines fully competent in antigen presentation and initiating primary T cell responses in vivo
US09/002,380 US6156307A (en) 1993-05-31 1998-01-02 Immortalization of dendritic cells with v-myc oncogene
GR990400460T GR3029374T3 (en) 1993-05-31 1999-02-11 Immortalization of denditric cells with v-myc oncogene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001118A IT1264516B1 (it) 1993-05-31 1993-05-31 Cellule dendritiche immortalizzate

Publications (3)

Publication Number Publication Date
ITMI931118A0 ITMI931118A0 (it) 1993-05-31
ITMI931118A1 ITMI931118A1 (it) 1994-12-01
IT1264516B1 true IT1264516B1 (it) 1996-09-24

Family

ID=11366291

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI001118A IT1264516B1 (it) 1993-05-31 1993-05-31 Cellule dendritiche immortalizzate

Country Status (15)

Country Link
US (2) US5856180A (it)
EP (1) EP0701604B1 (it)
JP (1) JP3834059B2 (it)
KR (1) KR100353220B1 (it)
AT (1) ATE173294T1 (it)
AU (1) AU686636B2 (it)
CA (1) CA2164102A1 (it)
DE (1) DE69414572T2 (it)
DK (1) DK0701604T3 (it)
ES (1) ES2126118T3 (it)
GR (1) GR3029374T3 (it)
HU (1) HUT73322A (it)
IT (1) IT1264516B1 (it)
WO (1) WO1994028113A1 (it)
ZA (1) ZA943782B (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4337396A1 (de) 1993-10-26 1995-04-27 Beiersdorf Ag Humane Zellinien mit Langerhans-Zell-Charakteristik
US5648219A (en) * 1995-06-07 1997-07-15 Zymogenetics, Inc. Immortalized dendritic cells
US5648248A (en) * 1994-12-30 1997-07-15 Boehringer Ingelheim International Gmbh Methods for producing differentiated cells from immature hematopoietic cells
BR9607081A (pt) * 1995-02-10 1997-11-11 Univ California Vetor célula célula de ocorréncia não natural vetor de retrovirus e métodos para a produção de uma célula geneticamente modificada para a produção de uma célula de ocorréncia não natural e para a terapia de transplante de células humanas
US5723333A (en) * 1995-02-10 1998-03-03 Regents Of The University Of California Human pancreatic cell lines: developments and uses
WO1996025664A1 (en) * 1995-02-17 1996-08-22 Immunotherapy, Inc. Immunotherapy screening, prognosis, and treatment methods and compositions
US5849589A (en) * 1996-03-11 1998-12-15 Duke University Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells
US6017527A (en) * 1996-07-10 2000-01-25 Immunex Corporation Activated dendritic cells and methods for their activation
EP0961824A4 (en) * 1996-07-10 2003-01-29 Immunex Corp DENDRITIC CELL ACTIVATION PROCESS
US20050169898A1 (en) 1997-04-15 2005-08-04 Jianlin Gong Cell fusions and methods of making and using the same
AU744042B2 (en) 1997-04-15 2002-02-14 Dana-Farber Cancer Institute, Inc. Dendritic cell hybrids
US7014848B1 (en) 1998-03-20 2006-03-21 Genzyme Corporation Enhanced anti-tumor immunity
AU3102799A (en) * 1998-03-20 1999-10-11 Genzyme Corporation Enhanced anti-tumor immunity
US7402307B2 (en) 1998-03-31 2008-07-22 Geron Corporation Method for identifying and killing cancer cells
WO1999050392A1 (en) 1998-03-31 1999-10-07 Geron Corporation Methods and compositions for eliciting an immune response to a telomerase antigen
US6387888B1 (en) 1998-09-30 2002-05-14 American Foundation For Biological Research, Inc. Immunotherapy of cancer through expression of truncated tumor or tumor-associated antigen
EP1351969A4 (en) * 2000-12-13 2006-04-05 Immunex Corp PROCESS RELATING TO THE PRODUCTION OF IMMORTAL DENDRITIC CELL LINES
EP1417229B1 (en) 2001-08-17 2011-06-15 Exothera L.L.C. Methods and compounds for the targeting of protein to exosomes
US8095735B2 (en) 2008-08-05 2012-01-10 Convey Computer Memory interleave for heterogeneous computing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648219A (en) * 1995-06-07 1997-07-15 Zymogenetics, Inc. Immortalized dendritic cells
US5648248A (en) * 1994-12-30 1997-07-15 Boehringer Ingelheim International Gmbh Methods for producing differentiated cells from immature hematopoietic cells

Also Published As

Publication number Publication date
ZA943782B (en) 1995-02-09
EP0701604B1 (en) 1998-11-11
AU6929994A (en) 1994-12-20
GR3029374T3 (en) 1999-05-28
EP0701604A1 (en) 1996-03-20
ES2126118T3 (es) 1999-03-16
KR100353220B1 (ko) 2003-12-31
AU686636B2 (en) 1998-02-12
DK0701604T3 (da) 1999-07-26
WO1994028113A1 (en) 1994-12-08
US6156307A (en) 2000-12-05
JPH09500523A (ja) 1997-01-21
CA2164102A1 (en) 1994-12-08
DE69414572T2 (de) 1999-07-29
ITMI931118A0 (it) 1993-05-31
HUT73322A (en) 1996-07-29
ATE173294T1 (de) 1998-11-15
ITMI931118A1 (it) 1994-12-01
DE69414572D1 (de) 1998-12-17
JP3834059B2 (ja) 2006-10-18
US5856180A (en) 1999-01-05
HU9503414D0 (en) 1996-01-29

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970529