IT1264516B1 - Cellule dendritiche immortalizzate - Google Patents
Cellule dendritiche immortalizzateInfo
- Publication number
- IT1264516B1 IT1264516B1 IT93MI001118A ITMI931118A IT1264516B1 IT 1264516 B1 IT1264516 B1 IT 1264516B1 IT 93MI001118 A IT93MI001118 A IT 93MI001118A IT MI931118 A ITMI931118 A IT MI931118A IT 1264516 B1 IT1264516 B1 IT 1264516B1
- Authority
- IT
- Italy
- Prior art keywords
- dendritic cells
- immortalized dendritic
- immortalized
- vectors containing
- retroviral vectors
- Prior art date
Links
- 210000004443 dendritic cell Anatomy 0.000 abstract 1
- 108700024542 myc Genes Proteins 0.000 abstract 1
- 230000001177 retroviral effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464452—Transcription factors, e.g. SOX or c-MYC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Cellule dendritiche sono state immortalizzate con vettori retrovirali contenenti l'oncogene v-myc.
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001118A IT1264516B1 (it) | 1993-05-31 | 1993-05-31 | Cellule dendritiche immortalizzate |
KR1019950705371A KR100353220B1 (ko) | 1993-05-31 | 1994-05-26 | V-myc종양형성유전자를이용한수상돌기세포의불멸화방법 |
AU69299/94A AU686636B2 (en) | 1993-05-31 | 1994-05-26 | Immortalization of denditric cells with V-MYC oncogene |
PCT/EP1994/001720 WO1994028113A1 (en) | 1993-05-31 | 1994-05-26 | Immortalization of denditric cells with v-myc oncogene |
EP94917670A EP0701604B1 (en) | 1993-05-31 | 1994-05-26 | Immortalization of denditric cells with v-myc oncogene |
DE69414572T DE69414572T2 (de) | 1993-05-31 | 1994-05-26 | Immortalisierung von dendritischen zellen mit dem v-myc onkogen |
ES94917670T ES2126118T3 (es) | 1993-05-31 | 1994-05-26 | Inmortalizacion de celulas dendriticas con el oncogen v-myc. |
JP50023195A JP3834059B2 (ja) | 1993-05-31 | 1994-05-26 | v−myc発癌遺伝子を用いる樹枝状細胞の固定 |
US08/549,666 US5856180A (en) | 1993-05-31 | 1994-05-26 | Immortalization of dendritic cells with V-MYC oncogene |
HU9503414A HUT73322A (en) | 1993-05-31 | 1994-05-26 | Immortalization of denditric cells with v-myc oncogene |
AT94917670T ATE173294T1 (de) | 1993-05-31 | 1994-05-26 | Immortalisierung von dendritischen zellen mit dem v-myc onkogen |
CA002164102A CA2164102A1 (en) | 1993-05-31 | 1994-05-26 | Immortalization of denditric cells with v-myc oncogene |
DK94917670T DK0701604T3 (da) | 1993-05-31 | 1994-05-26 | Immortalisering af dendritiske celler med V-myc-onkogenet |
ZA943782A ZA943782B (en) | 1993-05-31 | 1994-05-30 | Immortalization of dendritic cells and generation of functional dendritic cell lines fully competent in antigen presentation and initiating primary T cell responses in vivo |
US09/002,380 US6156307A (en) | 1993-05-31 | 1998-01-02 | Immortalization of dendritic cells with v-myc oncogene |
GR990400460T GR3029374T3 (en) | 1993-05-31 | 1999-02-11 | Immortalization of denditric cells with v-myc oncogene |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001118A IT1264516B1 (it) | 1993-05-31 | 1993-05-31 | Cellule dendritiche immortalizzate |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI931118A0 ITMI931118A0 (it) | 1993-05-31 |
ITMI931118A1 ITMI931118A1 (it) | 1994-12-01 |
IT1264516B1 true IT1264516B1 (it) | 1996-09-24 |
Family
ID=11366291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT93MI001118A IT1264516B1 (it) | 1993-05-31 | 1993-05-31 | Cellule dendritiche immortalizzate |
Country Status (15)
Country | Link |
---|---|
US (2) | US5856180A (it) |
EP (1) | EP0701604B1 (it) |
JP (1) | JP3834059B2 (it) |
KR (1) | KR100353220B1 (it) |
AT (1) | ATE173294T1 (it) |
AU (1) | AU686636B2 (it) |
CA (1) | CA2164102A1 (it) |
DE (1) | DE69414572T2 (it) |
DK (1) | DK0701604T3 (it) |
ES (1) | ES2126118T3 (it) |
GR (1) | GR3029374T3 (it) |
HU (1) | HUT73322A (it) |
IT (1) | IT1264516B1 (it) |
WO (1) | WO1994028113A1 (it) |
ZA (1) | ZA943782B (it) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4337396A1 (de) | 1993-10-26 | 1995-04-27 | Beiersdorf Ag | Humane Zellinien mit Langerhans-Zell-Charakteristik |
US5648219A (en) * | 1995-06-07 | 1997-07-15 | Zymogenetics, Inc. | Immortalized dendritic cells |
US5648248A (en) * | 1994-12-30 | 1997-07-15 | Boehringer Ingelheim International Gmbh | Methods for producing differentiated cells from immature hematopoietic cells |
BR9607081A (pt) * | 1995-02-10 | 1997-11-11 | Univ California | Vetor célula célula de ocorréncia não natural vetor de retrovirus e métodos para a produção de uma célula geneticamente modificada para a produção de uma célula de ocorréncia não natural e para a terapia de transplante de células humanas |
US5723333A (en) * | 1995-02-10 | 1998-03-03 | Regents Of The University Of California | Human pancreatic cell lines: developments and uses |
WO1996025664A1 (en) * | 1995-02-17 | 1996-08-22 | Immunotherapy, Inc. | Immunotherapy screening, prognosis, and treatment methods and compositions |
US5849589A (en) * | 1996-03-11 | 1998-12-15 | Duke University | Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells |
US6017527A (en) * | 1996-07-10 | 2000-01-25 | Immunex Corporation | Activated dendritic cells and methods for their activation |
EP0961824A4 (en) * | 1996-07-10 | 2003-01-29 | Immunex Corp | DENDRITIC CELL ACTIVATION PROCESS |
US20050169898A1 (en) | 1997-04-15 | 2005-08-04 | Jianlin Gong | Cell fusions and methods of making and using the same |
AU744042B2 (en) | 1997-04-15 | 2002-02-14 | Dana-Farber Cancer Institute, Inc. | Dendritic cell hybrids |
US7014848B1 (en) | 1998-03-20 | 2006-03-21 | Genzyme Corporation | Enhanced anti-tumor immunity |
AU3102799A (en) * | 1998-03-20 | 1999-10-11 | Genzyme Corporation | Enhanced anti-tumor immunity |
US7402307B2 (en) | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
WO1999050392A1 (en) | 1998-03-31 | 1999-10-07 | Geron Corporation | Methods and compositions for eliciting an immune response to a telomerase antigen |
US6387888B1 (en) | 1998-09-30 | 2002-05-14 | American Foundation For Biological Research, Inc. | Immunotherapy of cancer through expression of truncated tumor or tumor-associated antigen |
EP1351969A4 (en) * | 2000-12-13 | 2006-04-05 | Immunex Corp | PROCESS RELATING TO THE PRODUCTION OF IMMORTAL DENDRITIC CELL LINES |
EP1417229B1 (en) | 2001-08-17 | 2011-06-15 | Exothera L.L.C. | Methods and compounds for the targeting of protein to exosomes |
US8095735B2 (en) | 2008-08-05 | 2012-01-10 | Convey Computer | Memory interleave for heterogeneous computing |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648219A (en) * | 1995-06-07 | 1997-07-15 | Zymogenetics, Inc. | Immortalized dendritic cells |
US5648248A (en) * | 1994-12-30 | 1997-07-15 | Boehringer Ingelheim International Gmbh | Methods for producing differentiated cells from immature hematopoietic cells |
-
1993
- 1993-05-31 IT IT93MI001118A patent/IT1264516B1/it active IP Right Grant
-
1994
- 1994-05-26 US US08/549,666 patent/US5856180A/en not_active Expired - Fee Related
- 1994-05-26 DE DE69414572T patent/DE69414572T2/de not_active Expired - Fee Related
- 1994-05-26 KR KR1019950705371A patent/KR100353220B1/ko not_active IP Right Cessation
- 1994-05-26 AU AU69299/94A patent/AU686636B2/en not_active Ceased
- 1994-05-26 AT AT94917670T patent/ATE173294T1/de not_active IP Right Cessation
- 1994-05-26 ES ES94917670T patent/ES2126118T3/es not_active Expired - Lifetime
- 1994-05-26 WO PCT/EP1994/001720 patent/WO1994028113A1/en active IP Right Grant
- 1994-05-26 HU HU9503414A patent/HUT73322A/hu unknown
- 1994-05-26 DK DK94917670T patent/DK0701604T3/da active
- 1994-05-26 EP EP94917670A patent/EP0701604B1/en not_active Expired - Lifetime
- 1994-05-26 JP JP50023195A patent/JP3834059B2/ja not_active Expired - Fee Related
- 1994-05-26 CA CA002164102A patent/CA2164102A1/en not_active Abandoned
- 1994-05-30 ZA ZA943782A patent/ZA943782B/xx unknown
-
1998
- 1998-01-02 US US09/002,380 patent/US6156307A/en not_active Expired - Fee Related
-
1999
- 1999-02-11 GR GR990400460T patent/GR3029374T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ZA943782B (en) | 1995-02-09 |
EP0701604B1 (en) | 1998-11-11 |
AU6929994A (en) | 1994-12-20 |
GR3029374T3 (en) | 1999-05-28 |
EP0701604A1 (en) | 1996-03-20 |
ES2126118T3 (es) | 1999-03-16 |
KR100353220B1 (ko) | 2003-12-31 |
AU686636B2 (en) | 1998-02-12 |
DK0701604T3 (da) | 1999-07-26 |
WO1994028113A1 (en) | 1994-12-08 |
US6156307A (en) | 2000-12-05 |
JPH09500523A (ja) | 1997-01-21 |
CA2164102A1 (en) | 1994-12-08 |
DE69414572T2 (de) | 1999-07-29 |
ITMI931118A0 (it) | 1993-05-31 |
HUT73322A (en) | 1996-07-29 |
ATE173294T1 (de) | 1998-11-15 |
ITMI931118A1 (it) | 1994-12-01 |
DE69414572D1 (de) | 1998-12-17 |
JP3834059B2 (ja) | 2006-10-18 |
US5856180A (en) | 1999-01-05 |
HU9503414D0 (en) | 1996-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970529 |