JP2006515744A5 - - Google Patents
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- Publication number
- JP2006515744A5 JP2006515744A5 JP2004541534A JP2004541534A JP2006515744A5 JP 2006515744 A5 JP2006515744 A5 JP 2006515744A5 JP 2004541534 A JP2004541534 A JP 2004541534A JP 2004541534 A JP2004541534 A JP 2004541534A JP 2006515744 A5 JP2006515744 A5 JP 2006515744A5
- Authority
- JP
- Japan
- Prior art keywords
- mhc class
- epitope
- presenting
- key
- terminal element
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000043129 MHC class I family Human genes 0.000 claims 11
- 108091054437 MHC class I family Proteins 0.000 claims 11
- 102000043131 MHC class II family Human genes 0.000 claims 7
- 108091054438 MHC class II family Proteins 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 108010028930 invariant chain Proteins 0.000 claims 6
- 230000000890 antigenic effect Effects 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 3
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 claims 2
- 108010027412 Histocompatibility Antigens Class II Proteins 0.000 claims 2
- 102000018713 Histocompatibility Antigens Class II Human genes 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 2
- 210000004899 c-terminal region Anatomy 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- 102000008949 Histocompatibility Antigens Class I Human genes 0.000 claims 1
- 108010088652 Histocompatibility Antigens Class I Proteins 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000816 peptidomimetic Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000004962 physiological condition Effects 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 210000004896 polypeptide structure Anatomy 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/245,871 US20030235594A1 (en) | 1999-09-14 | 2002-09-17 | Ii-Key/antigenic epitope hybrid peptide vaccines |
| US10/253,286 US7179645B2 (en) | 2002-09-24 | 2002-09-24 | Ii-Key/antigenic epitope hybrid peptide vaccines |
| PCT/US2003/028574 WO2004030616A2 (en) | 2002-09-17 | 2003-09-12 | Ii-KEY/ANTIGENIC EPITOPE HYBRID PEPTIDE VACCINES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006515744A JP2006515744A (ja) | 2006-06-08 |
| JP2006515744A5 true JP2006515744A5 (enExample) | 2007-10-18 |
Family
ID=32072825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004541534A Pending JP2006515744A (ja) | 2002-09-17 | 2003-09-12 | Ｉｉ−Ｋｅｙ／抗原性エピトープハイブリッドペプチドワクチン |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1556072B1 (enExample) |
| JP (1) | JP2006515744A (enExample) |
| AU (1) | AU2003294220A1 (enExample) |
| CA (1) | CA2499123A1 (enExample) |
| WO (1) | WO2004030616A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601351B1 (en) | 2002-06-26 | 2009-10-13 | Human Genome Sciences, Inc. | Antibodies against protective antigen |
| US8354380B2 (en) * | 2004-06-17 | 2013-01-15 | Mannkind Corporation | NY-ESO-1 peptide analogs |
| ES2531483T3 (es) | 2005-06-15 | 2015-03-16 | The Ohio State University Research Foundation | Péptidos HER-2 |
| US20080095798A1 (en) * | 2006-10-18 | 2008-04-24 | Robert Humphreys | Ii-key enhanced vaccine potency |
| GB0706070D0 (en) * | 2007-03-28 | 2007-05-09 | Scancell Ltd | Nucleic acids |
| US20100234283A1 (en) | 2009-02-04 | 2010-09-16 | The Ohio State University Research Foundation | Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use |
| JP2012050440A (ja) * | 2011-09-16 | 2012-03-15 | Chiba Univ | ヒトＴｈ１／Ｔｈ２分化誘導の評価方法 |
| CN105120894B (zh) | 2012-10-30 | 2019-02-15 | 阿拉沃克斯有限公司 | 新颖的免疫治疗分子和其用途 |
| CN105992589A (zh) | 2013-09-25 | 2016-10-05 | 阿拉沃克斯有限公司 | 新型免疫治疗组合物及其用途 |
| ES2986555T3 (es) * | 2015-03-27 | 2024-11-11 | Immatics Biotechnologies Gmbh | Péptidos novedosos y combinación de péptidos para usarse en inmunoterapia contra diferentes tumores (SEQ ID 243 SPC25-001) |
| GB201507030D0 (en) * | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
| JP7320947B2 (ja) * | 2016-04-19 | 2023-08-04 | アンシス・エスア | 新規な免疫原性ＣＤ１ｄ結合ペプチド |
| CN108129558B (zh) * | 2017-12-21 | 2021-10-12 | 中国医学科学院北京协和医院 | 一种桦树花粉主要致敏蛋白Bet v 8的提取和分离纯化方法及应用 |
| US20230000908A1 (en) * | 2019-09-11 | 2023-01-05 | Ohio State Innovation Foundation | Engineered cells and uses thereof |
| EP4536244A2 (en) * | 2022-06-10 | 2025-04-16 | Ayass Bioscience LLC | Food allergen processing and desensitization by aptamers |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
| JPS60500673A (ja) | 1983-03-08 | 1985-05-09 | コモンウエルス セラム ラボラトリ−ズ コミツシヨン | 抗原活性を有するアミノ酸配列 |
| US4650764A (en) | 1983-04-12 | 1987-03-17 | Wisconsin Alumni Research Foundation | Helper cell |
| CA1255586A (en) | 1984-07-24 | 1989-06-13 | Hendrik M. Geysen | Method of determining mimotopes |
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US6133029A (en) | 1988-03-21 | 2000-10-17 | Chiron Corporation | Replication defective viral vectors for infecting human cells |
| US5194425A (en) | 1988-06-23 | 1993-03-16 | Anergen, Inc. | Mhc-mediated toxic conjugates useful in ameliorating autoimmunity |
| AU642403B2 (en) | 1989-02-17 | 1993-10-21 | Coselco Mimotopes Pty Ltd | Method for the use and synthesis of peptides |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5126132A (en) | 1989-08-21 | 1992-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor infiltrating lymphocytes as a treatment modality for human cancer |
| EP0497922B1 (en) | 1989-10-24 | 2002-01-30 | Chiron Corporation | Infective protein delivery system |
| US5747334A (en) | 1990-02-15 | 1998-05-05 | The University Of North Carolina At Chapel Hill | Random peptide library |
| DE69130831T2 (de) | 1990-11-21 | 1999-09-16 | Iterex Pharmaceuticals Ltd. Partnership, San Diego | Synthese äquimolarer mischungen vielzähliger oligomere, speziell oligopeptidmischungen |
| US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
| JPH07501942A (ja) | 1991-11-29 | 1995-03-02 | カイロン コーポレイション | 抗ガン免疫療法用ベクター構成体 |
| US5679527A (en) | 1992-03-25 | 1997-10-21 | Antigen Express, Inc. | Modification of polypeptide structure |
| WO1994012520A1 (en) | 1992-11-20 | 1994-06-09 | Enzon, Inc. | Linker for linked fusion polypeptides |
| US5559028A (en) * | 1993-05-19 | 1996-09-24 | Antigen Express, Inc. | Methods of enhancing or antigen presentation to T cells inhibiting |
| AU7478394A (en) | 1993-08-06 | 1995-02-28 | Cytel Corporation | Methods for (ex vivo) therapy using peptide-loaded antigen presenting cells for the activation of ctl |
| US5874214A (en) | 1995-04-25 | 1999-02-23 | Irori | Remotely programmable matrices with memories |
| DE69628731T3 (de) | 1995-11-01 | 2012-09-20 | Bracco Suisse S.A. | Gezielte magnetisch markierte molekularmarkersysteme als nmr-bilderzeugungsmittel |
| WO1997049430A1 (en) | 1996-06-26 | 1997-12-31 | Antigen Express, Inc. | Immunotherapy by modulation of antigen presentation |
| US6432409B1 (en) | 1999-09-14 | 2002-08-13 | Antigen Express, Inc. | Hybrid peptides modulate the immune response |
-
2003
- 2003-09-12 JP JP2004541534A patent/JP2006515744A/ja active Pending
- 2003-09-12 CA CA002499123A patent/CA2499123A1/en not_active Abandoned
- 2003-09-12 WO PCT/US2003/028574 patent/WO2004030616A2/en not_active Ceased
- 2003-09-12 AU AU2003294220A patent/AU2003294220A1/en not_active Abandoned
- 2003-09-12 EP EP03789700A patent/EP1556072B1/en not_active Expired - Lifetime
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