JP2006515744A - Ii−Key/抗原性エピトープハイブリッドペプチドワクチン - Google Patents

Ii−Key/抗原性エピトープハイブリッドペプチドワクチン Download PDF

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Publication number
JP2006515744A
JP2006515744A JP2004541534A JP2004541534A JP2006515744A JP 2006515744 A JP2006515744 A JP 2006515744A JP 2004541534 A JP2004541534 A JP 2004541534A JP 2004541534 A JP2004541534 A JP 2004541534A JP 2006515744 A JP2006515744 A JP 2006515744A
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Japan
Prior art keywords
mhc class
epitope
presented
amino acid
peptide
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Pending
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JP2004541534A
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English (en)
Japanese (ja)
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JP2006515744A5 (enExample
Inventor
ハンフリーズ,ロバート・イー
スー,ミンツエン
Original Assignee
アンテイジエン・エクスプレス・インコーポレーテツド
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Priority claimed from US10/245,871 external-priority patent/US20030235594A1/en
Priority claimed from US10/253,286 external-priority patent/US7179645B2/en
Application filed by アンテイジエン・エクスプレス・インコーポレーテツド filed Critical アンテイジエン・エクスプレス・インコーポレーテツド
Publication of JP2006515744A publication Critical patent/JP2006515744A/ja
Publication of JP2006515744A5 publication Critical patent/JP2006515744A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2004541534A 2002-09-17 2003-09-12 Ii−Key/抗原性エピトープハイブリッドペプチドワクチン Pending JP2006515744A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/245,871 US20030235594A1 (en) 1999-09-14 2002-09-17 Ii-Key/antigenic epitope hybrid peptide vaccines
US10/253,286 US7179645B2 (en) 2002-09-24 2002-09-24 Ii-Key/antigenic epitope hybrid peptide vaccines
PCT/US2003/028574 WO2004030616A2 (en) 2002-09-17 2003-09-12 Ii-KEY/ANTIGENIC EPITOPE HYBRID PEPTIDE VACCINES

Publications (2)

Publication Number Publication Date
JP2006515744A true JP2006515744A (ja) 2006-06-08
JP2006515744A5 JP2006515744A5 (enExample) 2007-10-18

Family

ID=32072825

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004541534A Pending JP2006515744A (ja) 2002-09-17 2003-09-12 Ii−Key/抗原性エピトープハイブリッドペプチドワクチン

Country Status (5)

Country Link
EP (1) EP1556072B1 (enExample)
JP (1) JP2006515744A (enExample)
AU (1) AU2003294220A1 (enExample)
CA (1) CA2499123A1 (enExample)
WO (1) WO2004030616A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015533837A (ja) * 2012-10-30 2015-11-26 モナッシュ ユニバーシティ 新規免疫療法用分子およびその使用
JP2016533341A (ja) * 2013-09-25 2016-10-27 アラヴァックス ピーティーワイ リミテッド 新規免疫療法組成物およびその使用
JP2024069322A (ja) * 2015-04-24 2024-05-21 イマティクス バイオテクノロジーズ ゲーエムベーハー Nsclcをはじめとする肺がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチド組み合わせ
JP2024147612A (ja) * 2015-03-27 2024-10-16 イマティクス バイオテクノロジーズ ゲーエムベーハー 様々な腫瘍に対する免疫療法で使用される新規ペプチドおよびペプチドの組み合わせ

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601351B1 (en) 2002-06-26 2009-10-13 Human Genome Sciences, Inc. Antibodies against protective antigen
US8354380B2 (en) * 2004-06-17 2013-01-15 Mannkind Corporation NY-ESO-1 peptide analogs
ES2531483T3 (es) 2005-06-15 2015-03-16 The Ohio State University Research Foundation Péptidos HER-2
US20080095798A1 (en) * 2006-10-18 2008-04-24 Robert Humphreys Ii-key enhanced vaccine potency
GB0706070D0 (en) * 2007-03-28 2007-05-09 Scancell Ltd Nucleic acids
US20100234283A1 (en) 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
JP2012050440A (ja) * 2011-09-16 2012-03-15 Chiba Univ ヒトTh1/Th2分化誘導の評価方法
JP7320947B2 (ja) * 2016-04-19 2023-08-04 アンシス・エスア 新規な免疫原性CD1d結合ペプチド
CN108129558B (zh) * 2017-12-21 2021-10-12 中国医学科学院北京协和医院 一种桦树花粉主要致敏蛋白Bet v 8的提取和分离纯化方法及应用
US20230000908A1 (en) * 2019-09-11 2023-01-05 Ohio State Innovation Foundation Engineered cells and uses thereof
EP4536244A2 (en) * 2022-06-10 2025-04-16 Ayass Bioscience LLC Food allergen processing and desensitization by aptamers

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021193A1 (en) * 1999-09-14 2001-03-29 Antigen Express, Inc. Hybrid peptides modulate the immune response

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NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
JPS60500673A (ja) 1983-03-08 1985-05-09 コモンウエルス セラム ラボラトリ−ズ コミツシヨン 抗原活性を有するアミノ酸配列
US4650764A (en) 1983-04-12 1987-03-17 Wisconsin Alumni Research Foundation Helper cell
CA1255586A (en) 1984-07-24 1989-06-13 Hendrik M. Geysen Method of determining mimotopes
US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US6133029A (en) 1988-03-21 2000-10-17 Chiron Corporation Replication defective viral vectors for infecting human cells
US5194425A (en) 1988-06-23 1993-03-16 Anergen, Inc. Mhc-mediated toxic conjugates useful in ameliorating autoimmunity
AU642403B2 (en) 1989-02-17 1993-10-21 Coselco Mimotopes Pty Ltd Method for the use and synthesis of peptides
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5126132A (en) 1989-08-21 1992-06-30 The United States Of America As Represented By The Department Of Health And Human Services Tumor infiltrating lymphocytes as a treatment modality for human cancer
EP0497922B1 (en) 1989-10-24 2002-01-30 Chiron Corporation Infective protein delivery system
US5747334A (en) 1990-02-15 1998-05-05 The University Of North Carolina At Chapel Hill Random peptide library
DE69130831T2 (de) 1990-11-21 1999-09-16 Iterex Pharmaceuticals Ltd. Partnership, San Diego Synthese äquimolarer mischungen vielzähliger oligomere, speziell oligopeptidmischungen
US5270170A (en) 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
JPH07501942A (ja) 1991-11-29 1995-03-02 カイロン コーポレイション 抗ガン免疫療法用ベクター構成体
US5679527A (en) 1992-03-25 1997-10-21 Antigen Express, Inc. Modification of polypeptide structure
WO1994012520A1 (en) 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
US5559028A (en) * 1993-05-19 1996-09-24 Antigen Express, Inc. Methods of enhancing or antigen presentation to T cells inhibiting
AU7478394A (en) 1993-08-06 1995-02-28 Cytel Corporation Methods for (ex vivo) therapy using peptide-loaded antigen presenting cells for the activation of ctl
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
DE69628731T3 (de) 1995-11-01 2012-09-20 Bracco Suisse S.A. Gezielte magnetisch markierte molekularmarkersysteme als nmr-bilderzeugungsmittel
WO1997049430A1 (en) 1996-06-26 1997-12-31 Antigen Express, Inc. Immunotherapy by modulation of antigen presentation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021193A1 (en) * 1999-09-14 2001-03-29 Antigen Express, Inc. Hybrid peptides modulate the immune response

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015533837A (ja) * 2012-10-30 2015-11-26 モナッシュ ユニバーシティ 新規免疫療法用分子およびその使用
JP2018184447A (ja) * 2012-10-30 2018-11-22 アラヴァックス ピーティーワイ リミテッド 新規免疫療法用分子およびその使用
US11096994B2 (en) 2012-10-30 2021-08-24 Aravax Pty Ltd Immunotherapeutic molecules and uses thereof
JP2021185162A (ja) * 2012-10-30 2021-12-09 アラヴァックス ピーティーワイ リミテッド 新規免疫療法用分子およびその使用
US11980658B2 (en) 2012-10-30 2024-05-14 Aravax Pty Ltd Immunotherapeutic molecules and uses thereof
JP2016533341A (ja) * 2013-09-25 2016-10-27 アラヴァックス ピーティーワイ リミテッド 新規免疫療法組成物およびその使用
US11266737B2 (en) 2013-09-25 2022-03-08 Aravax Pty Ltd Immunotherapeutic composition and uses thereof
US11986522B2 (en) 2013-09-25 2024-05-21 Ara Vax Pty Ltd Immunotherapeutic composition and uses thereof
JP2024147612A (ja) * 2015-03-27 2024-10-16 イマティクス バイオテクノロジーズ ゲーエムベーハー 様々な腫瘍に対する免疫療法で使用される新規ペプチドおよびペプチドの組み合わせ
JP2024069322A (ja) * 2015-04-24 2024-05-21 イマティクス バイオテクノロジーズ ゲーエムベーハー Nsclcをはじめとする肺がんおよびその他のがんに対する免疫療法において使用するための新規ペプチドおよびペプチド組み合わせ

Also Published As

Publication number Publication date
EP1556072B1 (en) 2010-05-19
AU2003294220A1 (en) 2004-04-23
EP1556072A2 (en) 2005-07-27
WO2004030616A3 (en) 2004-10-07
AU2003294220A8 (en) 2004-04-23
CA2499123A1 (en) 2004-04-15
EP1556072A4 (en) 2005-12-21
WO2004030616A2 (en) 2004-04-15

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