JP2003520288A5 - - Google Patents
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- Publication number
- JP2003520288A5 JP2003520288A5 JP2001552800A JP2001552800A JP2003520288A5 JP 2003520288 A5 JP2003520288 A5 JP 2003520288A5 JP 2001552800 A JP2001552800 A JP 2001552800A JP 2001552800 A JP2001552800 A JP 2001552800A JP 2003520288 A5 JP2003520288 A5 JP 2003520288A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- independently
- yes
- varies
- fifteen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 11
- 150000001875 compounds Chemical class 0.000 description 9
- 238000000034 method Methods 0.000 description 7
- 229910052739 hydrogen Inorganic materials 0.000 description 5
- 239000001257 hydrogen Substances 0.000 description 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 235000010469 Glycine max Nutrition 0.000 description 4
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 description 3
- 125000003545 alkoxy group Chemical group 0.000 description 3
- 125000003118 aryl group Chemical group 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 238000002405 diagnostic procedure Methods 0.000 description 3
- 150000002431 hydrogen Chemical class 0.000 description 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- 238000000149 argon plasma sintering Methods 0.000 description 2
- 230000001268 conjugating effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 208000037260 Atherosclerotic Plaque Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 125000004103 aminoalkyl group Chemical group 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 125000004093 cyano group Chemical group *C#N 0.000 description 1
- 238000001839 endoscopy Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- -1 nitro Chemical group 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/484,318 | 2000-01-18 | ||
| US09/484,318 US6180085B1 (en) | 2000-01-18 | 2000-01-18 | Dyes |
| PCT/US2001/001469 WO2001052745A1 (en) | 2000-01-18 | 2001-01-17 | Novel dyes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003520288A JP2003520288A (ja) | 2003-07-02 |
| JP2003520288A5 true JP2003520288A5 (enExample) | 2008-08-28 |
Family
ID=23923647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001552800A Pending JP2003520288A (ja) | 2000-01-18 | 2001-01-17 | 新規の染料 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6180085B1 (enExample) |
| EP (2) | EP1559374B1 (enExample) |
| JP (1) | JP2003520288A (enExample) |
| AT (2) | ATE399505T1 (enExample) |
| AU (1) | AU2001232819A1 (enExample) |
| DE (2) | DE60134680D1 (enExample) |
| ES (2) | ES2239122T3 (enExample) |
| WO (1) | WO2001052745A1 (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7255851B2 (en) * | 1994-07-01 | 2007-08-14 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive localization of a light-emitting conjugate in a mammal |
| US6133445A (en) * | 1997-12-17 | 2000-10-17 | Carnegie Mellon University | Rigidized trimethine cyanine dyes |
| US6939532B2 (en) * | 2000-01-18 | 2005-09-06 | Mallinckrodt, Inc. | Versatile hydrophilic dyes |
| US6395257B1 (en) | 2000-01-18 | 2002-05-28 | Mallinckrodt Inc. | Dendrimer precursor dyes for imaging |
| US7230088B2 (en) * | 2001-07-03 | 2007-06-12 | Mallinckrodt, Inc. | Compounds for dual photodiagnosis and therapy |
| US20030017164A1 (en) | 2001-07-03 | 2003-01-23 | Mallinckrodt Inc. | Dye-azide compounds for dual phototherapy |
| US6180085B1 (en) * | 2000-01-18 | 2001-01-30 | Mallinckrodt Inc. | Dyes |
| US7790144B2 (en) * | 2000-01-18 | 2010-09-07 | Mallinckrodt Inc. | Receptor-avid exogenous optical contrast and therapeutic agents |
| US20080233050A1 (en) * | 2000-01-18 | 2008-09-25 | Mallinckrodt Inc. | Diagnostic and therapeutic optical agents |
| US6673334B1 (en) * | 2000-10-16 | 2004-01-06 | Mallinkcrodt, Inc. | Light sensitive compounds for instant determination of organ function |
| US7556797B2 (en) * | 2000-10-16 | 2009-07-07 | Mallinckrodt Inc. | Minimally invasive physiological function monitoring agents |
| US20040180809A1 (en) * | 2000-10-16 | 2004-09-16 | Mallinckrodt Inc. | Tissue-specific exogenous optical agents |
| US20070092450A1 (en) * | 2000-10-16 | 2007-04-26 | Mallinckrodt Inc. | Tissue-specific exogenous optical agents |
| US20030105300A1 (en) * | 2001-10-17 | 2003-06-05 | Mallinckrodt Inc. | Tumor targeted photodiagnostic-phototherapeutic agents |
| US20030105299A1 (en) * | 2001-10-17 | 2003-06-05 | Mallinckrodt Inc. | Carbocyanine dyes for tandem, photodiagnostic and therapeutic applications |
| EP1525265B1 (en) | 2002-05-10 | 2011-07-20 | Carnegie Mellon University | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups |
| US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
| DE10302787A1 (de) * | 2003-01-24 | 2004-08-12 | Schering Ag | Hydrophile, Thiol-reaktive Cyaninfarbstoffe und deren Konjugate mit Biomolekülen für die Fluoreszenzdiagnostik |
| WO2004068405A2 (en) * | 2003-01-25 | 2004-08-12 | Oraevsky Alexander A | High contrast optoacoustical imaging using nanoparticles |
| JP2007518727A (ja) | 2004-01-08 | 2007-07-12 | ウニヴェルジテート・チューリッヒ | 配位子としてビタミンｂ１２を有する金属錯体 |
| DE102004002758A1 (de) * | 2004-01-20 | 2005-08-04 | Bayer Chemicals Ag | Metallkomplexe als lichtabsorbierende Verbindungen in der Informationsschicht von optischen Datenträgern |
| CN101203248A (zh) * | 2005-06-21 | 2008-06-18 | 马林克罗特公司 | 光学成像造影剂 |
| US8227621B2 (en) * | 2005-06-30 | 2012-07-24 | Li-Cor, Inc. | Cyanine dyes and methods of use |
| FR2889700B1 (fr) | 2005-08-11 | 2012-11-23 | Synthinnove Lab | Marqueurs, leur procede de fabrication et leurs applications |
| US20100022449A1 (en) * | 2006-03-09 | 2010-01-28 | Mallinckrodt Inc. | Receptor-avid exogenous optical contrast and therapeutic agents |
| WO2009012109A2 (en) * | 2007-07-13 | 2009-01-22 | Emory University | Cyanine-containing compounds for cancer imaging and treatment |
| US8088163B1 (en) | 2008-02-06 | 2012-01-03 | Kleiner Jeffrey B | Tools and methods for spinal fusion |
| US20090214436A1 (en) | 2008-02-18 | 2009-08-27 | Washington University | Dichromic fluorescent compounds |
| US20210378834A1 (en) | 2008-05-22 | 2021-12-09 | Spinal Surgical Strategies, Inc., A Nevada Corporation D/B/A Kleiner Device Labs | Spinal fusion cage system with inserter |
| USD853560S1 (en) | 2008-10-09 | 2019-07-09 | Nuvasive, Inc. | Spinal implant insertion device |
| US9717403B2 (en) | 2008-12-05 | 2017-08-01 | Jeffrey B. Kleiner | Method and apparatus for performing retro peritoneal dissection |
| US8366748B2 (en) | 2008-12-05 | 2013-02-05 | Kleiner Jeffrey | Apparatus and method of spinal implant and fusion |
| US8864654B2 (en) | 2010-04-20 | 2014-10-21 | Jeffrey B. Kleiner | Method and apparatus for performing retro peritoneal dissection |
| US9247943B1 (en) | 2009-02-06 | 2016-02-02 | Kleiner Intellectual Property, Llc | Devices and methods for preparing an intervertebral workspace |
| USD656610S1 (en) | 2009-02-06 | 2012-03-27 | Kleiner Jeffrey B | Spinal distraction instrument |
| JP2012524153A (ja) * | 2009-04-17 | 2012-10-11 | ライコア インコーポレイテッド | 置換シアニン染料を用いた蛍光イメージング |
| US9433700B2 (en) | 2009-04-27 | 2016-09-06 | Medibeacon Inc. | Tissue sealant compositions, vascular closure devices, and uses thereof |
| US9186193B2 (en) | 2009-09-18 | 2015-11-17 | Spinal Surgical Strategies, Llc | Fusion cage with combined biological delivery system |
| US8906028B2 (en) | 2009-09-18 | 2014-12-09 | Spinal Surgical Strategies, Llc | Bone graft delivery device and method of using the same |
| US9060877B2 (en) | 2009-09-18 | 2015-06-23 | Spinal Surgical Strategies, Llc | Fusion cage with combined biological delivery system |
| US9173694B2 (en) | 2009-09-18 | 2015-11-03 | Spinal Surgical Strategies, Llc | Fusion cage with combined biological delivery system |
| US20170238984A1 (en) | 2009-09-18 | 2017-08-24 | Spinal Surgical Strategies, Llc | Bone graft delivery device with positioning handle |
| US8685031B2 (en) | 2009-09-18 | 2014-04-01 | Spinal Surgical Strategies, Llc | Bone graft delivery system |
| US9629729B2 (en) | 2009-09-18 | 2017-04-25 | Spinal Surgical Strategies, Llc | Biological delivery system with adaptable fusion cage interface |
| US10973656B2 (en) | 2009-09-18 | 2021-04-13 | Spinal Surgical Strategies, Inc. | Bone graft delivery system and method for using same |
| USD750249S1 (en) | 2014-10-20 | 2016-02-23 | Spinal Surgical Strategies, Llc | Expandable fusion cage |
| US10245159B1 (en) | 2009-09-18 | 2019-04-02 | Spinal Surgical Strategies, Llc | Bone graft delivery system and method for using same |
| USD723682S1 (en) | 2013-05-03 | 2015-03-03 | Spinal Surgical Strategies, Llc | Bone graft delivery tool |
| US9808320B2 (en) | 2010-02-08 | 2017-11-07 | Jeffrey B. Kleiner | Method and system for identification of a center of a patient's body part |
| US8690887B2 (en) | 2010-02-08 | 2014-04-08 | Jeffrey B. Kleiner | Method and system for identification of a center of a vertebral disc space and corresponding central axis of a spinal column |
| CN102260352B (zh) * | 2010-05-28 | 2013-11-20 | 山东先声麦得津生物制药有限公司 | 靶向性白细胞介素融合蛋白及其制备方法与应用 |
| WO2012054749A1 (en) | 2010-10-20 | 2012-04-26 | Li-Cor, Inc. | Cyanine dyes and their conjugates |
| CN104470546B (zh) | 2012-07-20 | 2018-02-27 | 佳能株式会社 | 化合物和含有所述化合物的光声成像造影剂 |
| KR20150130557A (ko) | 2013-03-15 | 2015-11-23 | 글렌 레인 패밀리 리미티드 리에빌러티 리미티드 파트너쉽 | 조정 가능한 질량 분해 애퍼쳐 |
| US10806804B2 (en) * | 2015-05-06 | 2020-10-20 | Washington University | Compounds having RD targeting motifs and methods of use thereof |
| USD797290S1 (en) | 2015-10-19 | 2017-09-12 | Spinal Surgical Strategies, Llc | Bone graft delivery tool |
| US9862682B2 (en) | 2016-01-08 | 2018-01-09 | BroadPharm | Functionalized pegylated cyanine compounds, pharmaceutical compositions, and methods of use thereof |
| KR101804063B1 (ko) | 2016-08-03 | 2017-12-01 | 전남대학교산학협력단 | 종양 표적화 근적외선 형광 탐지자 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4040825A (en) * | 1975-03-18 | 1977-08-09 | Ciba-Geigy Ag | Spectral sensitization of photographic material with natural colloids containing sensitizing dye groups |
| DD256768B5 (de) * | 1984-09-27 | 1994-05-11 | Wolfen Filmfab Gmbh | Verfahren zum Einbringen von optischen Sensibilisatoren durch Dispergierung |
| US5096801A (en) * | 1989-04-03 | 1992-03-17 | Fuji Photo Film Co., Ltd. | Color image recording method |
| JPH03132654A (ja) * | 1989-10-18 | 1991-06-06 | Konica Corp | ハロゲン化銀カラー写真感光材料 |
| JPH04186342A (ja) * | 1990-11-21 | 1992-07-03 | Fuji Photo Film Co Ltd | 写真感光材料を用いるカラープルーフの作成方法 |
| JPH06102624A (ja) * | 1992-09-18 | 1994-04-15 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
| JPH0735749A (ja) * | 1993-07-19 | 1995-02-07 | Ibiden Co Ltd | Ｏ−アルキル化アミノグリカンを用いた免疫測定用標識試薬 |
| JPH09227378A (ja) * | 1996-02-20 | 1997-09-02 | Fuji Photo Film Co Ltd | 抗癌性組成物 |
| DE19649971A1 (de) * | 1996-11-19 | 1998-05-28 | Diagnostikforschung Inst | Optische Diagnostika zur Diagnostik neurodegenerativer Krankheiten mittels Nahinfrarot-Strahlung (NIR-Strahlung) |
| ATE441434T1 (de) * | 1998-04-03 | 2009-09-15 | Mallinckrodt Inc | Nichtkovalente biokonjugate für diagnose und therapie |
| DE19841985A1 (de) * | 1998-09-03 | 2000-03-09 | Schering Ag | Dialkylsulfonsäure- und Dialkylcarbonsäure-Derivate |
| JP2000098524A (ja) * | 1998-09-25 | 2000-04-07 | Konica Corp | ハロゲン化銀乳剤、ハロゲン化銀感光材料及び熱現像感光材料 |
| US6217848B1 (en) * | 1999-05-20 | 2001-04-17 | Mallinckrodt Inc. | Cyanine and indocyanine dye bioconjugates for biomedical applications |
| US6180085B1 (en) * | 2000-01-18 | 2001-01-30 | Mallinckrodt Inc. | Dyes |
-
2000
- 2000-01-18 US US09/484,318 patent/US6180085B1/en not_active Expired - Fee Related
-
2001
- 2001-01-17 EP EP05005127A patent/EP1559374B1/en not_active Expired - Lifetime
- 2001-01-17 AU AU2001232819A patent/AU2001232819A1/en not_active Abandoned
- 2001-01-17 AT AT05005127T patent/ATE399505T1/de not_active IP Right Cessation
- 2001-01-17 EP EP01904883A patent/EP1250092B1/en not_active Expired - Lifetime
- 2001-01-17 WO PCT/US2001/001469 patent/WO2001052745A1/en not_active Ceased
- 2001-01-17 DE DE60134680T patent/DE60134680D1/de not_active Expired - Lifetime
- 2001-01-17 DE DE60109740T patent/DE60109740T8/de active Active
- 2001-01-17 AT AT01904883T patent/ATE291878T1/de not_active IP Right Cessation
- 2001-01-17 ES ES01904883T patent/ES2239122T3/es not_active Expired - Lifetime
- 2001-01-17 ES ES05005127T patent/ES2309609T3/es not_active Expired - Lifetime
- 2001-01-17 JP JP2001552800A patent/JP2003520288A/ja active Pending
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