JP2003529632A5 - - Google Patents
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- Publication number
- JP2003529632A5 JP2003529632A5 JP2001552799A JP2001552799A JP2003529632A5 JP 2003529632 A5 JP2003529632 A5 JP 2003529632A5 JP 2001552799 A JP2001552799 A JP 2001552799A JP 2001552799 A JP2001552799 A JP 2001552799A JP 2003529632 A5 JP2003529632 A5 JP 2003529632A5
- Authority
- JP
- Japan
- Prior art keywords
- och
- conh
- nhco
- independently
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 description 9
- 238000002405 diagnostic procedure Methods 0.000 description 5
- 239000002184 metal Substances 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 108090000765 processed proteins & peptides Proteins 0.000 description 4
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 150000002431 hydrogen Chemical class 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 102000002068 Glycopeptides Human genes 0.000 description 2
- 108010015899 Glycopeptides Proteins 0.000 description 2
- 238000000149 argon plasma sintering Methods 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 125000002837 carbocyclic group Chemical group 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 125000000623 heterocyclic group Chemical group 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 229920001542 oligosaccharide Polymers 0.000 description 2
- 150000002482 oligosaccharides Chemical class 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 125000004434 sulfur atom Chemical group 0.000 description 2
- 125000004008 6 membered carbocyclic group Chemical group 0.000 description 1
- 208000037260 Atherosclerotic Plaque Diseases 0.000 description 1
- 102000013585 Bombesin Human genes 0.000 description 1
- 108010051479 Bombesin Proteins 0.000 description 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 description 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- DNDCVAGJPBKION-DOPDSADYSA-N bombesin Chemical group C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC=1NC2=CC=CC=C2C=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1NC(=O)CC1)C(C)C)C1=CN=CN1 DNDCVAGJPBKION-DOPDSADYSA-N 0.000 description 1
- 150000004696 coordination complex Chemical class 0.000 description 1
- 125000004093 cyano group Chemical group *C#N 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000001839 endoscopy Methods 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- CFODQUSMSYDHBS-UHFFFAOYSA-N octreotate Chemical group O=C1NC(CC=2C=CC=CC=2)C(=O)NC(CC=2[C]3C=CC=CC3=NC=2)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(C(=O)NC(C(O)C)C(O)=O)CSSCC1NC(=O)C(N)CC1=CC=CC=C1 CFODQUSMSYDHBS-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000000816 peptidomimetic Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/484,319 US6180086B1 (en) | 2000-01-18 | 2000-01-18 | Hydrophilic cyanine dyes |
| US09/484,319 | 2000-01-18 | ||
| US09/757,332 | 2001-01-09 | ||
| US09/757,332 US7011817B2 (en) | 2000-01-18 | 2001-01-09 | Hydrophilic cyanine dyes |
| PCT/US2001/001468 WO2001052744A1 (en) | 2000-01-18 | 2001-01-17 | Hydrophilic cyanine dyes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011047019A Division JP2011116773A (ja) | 2000-01-18 | 2011-03-03 | 親水性シアニン染料 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003529632A JP2003529632A (ja) | 2003-10-07 |
| JP2003529632A5 true JP2003529632A5 (enExample) | 2008-08-21 |
Family
ID=27047953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001552799A Pending JP2003529632A (ja) | 2000-01-18 | 2001-01-17 | 親水性シアニン染料 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1250091B1 (enExample) |
| JP (1) | JP2003529632A (enExample) |
| AT (1) | ATE392183T1 (enExample) |
| AU (1) | AU2001232818A1 (enExample) |
| WO (1) | WO2001052744A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7790144B2 (en) * | 2000-01-18 | 2010-09-07 | Mallinckrodt Inc. | Receptor-avid exogenous optical contrast and therapeutic agents |
| US6663847B1 (en) * | 2000-10-13 | 2003-12-16 | Mallinckrodt Inc. | Dynamic organ function monitoring agents |
| US6733744B1 (en) * | 2000-10-16 | 2004-05-11 | Mallinckrodt Inc. | Indole compounds as minimally invasive physiological function monitoring agents |
| US7556797B2 (en) * | 2000-10-16 | 2009-07-07 | Mallinckrodt Inc. | Minimally invasive physiological function monitoring agents |
| US20030105299A1 (en) * | 2001-10-17 | 2003-06-05 | Mallinckrodt Inc. | Carbocyanine dyes for tandem, photodiagnostic and therapeutic applications |
| US20030105300A1 (en) * | 2001-10-17 | 2003-06-05 | Mallinckrodt Inc. | Tumor targeted photodiagnostic-phototherapeutic agents |
| US20030152577A1 (en) * | 2002-02-07 | 2003-08-14 | Mallinckrodt Inc. | Dye-bioconjugates for simultaneous optical diagnostic and therapeutic applications |
| EP1506402A2 (en) * | 2002-03-28 | 2005-02-16 | Rutgers, The State University of New Jersey | Bis-transition-metal-chelate-probes |
| US6919333B2 (en) * | 2002-11-12 | 2005-07-19 | Rutgers, The State University Of New Jersey | Bis-transition-metal-chelate probes |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8615995D0 (en) * | 1986-07-01 | 1986-08-06 | Glaxo Group Ltd | Veterinary preparations |
| DE3721850A1 (de) * | 1987-07-02 | 1989-01-12 | Bayer Ag | Indolin-carbocyaninfarbstoffe |
| JP3354975B2 (ja) * | 1992-10-06 | 2002-12-09 | イビデン株式会社 | 蛍光標識試薬および蛍光免疫測定法 |
| US5631364A (en) * | 1994-03-31 | 1997-05-20 | Axis Biochemicals Asa | Labelled boronic acid derivatives |
| AU3008595A (en) * | 1994-06-30 | 1996-01-25 | Biometric Imaging, Inc. | N-heteroaromatic ion and iminium ion substituted cyanine dyes for use as fluorescence labels |
| IT1276833B1 (it) * | 1995-10-09 | 1997-11-03 | Sorin Biomedica Cardio Spa | Coloranti fluorescenti della famiglia della solfo benz e indocianina |
| KR20010075107A (ko) * | 1998-09-17 | 2001-08-09 | 다께다 가즈히꼬 | 광화학 요법 치료제 |
| DE19911102A1 (de) * | 1999-03-12 | 2000-09-14 | Few Chemicals Gmbh Wolfen | Cyanin-Farbstoffe |
| JP4041613B2 (ja) * | 1999-03-12 | 2008-01-30 | 富士フイルム株式会社 | 画像形成材料 |
| US6180086B1 (en) * | 2000-01-18 | 2001-01-30 | Mallinckrodt Inc. | Hydrophilic cyanine dyes |
-
2001
- 2001-01-17 JP JP2001552799A patent/JP2003529632A/ja active Pending
- 2001-01-17 WO PCT/US2001/001468 patent/WO2001052744A1/en not_active Ceased
- 2001-01-17 EP EP01904882A patent/EP1250091B1/en not_active Expired - Lifetime
- 2001-01-17 AT AT01904882T patent/ATE392183T1/de not_active IP Right Cessation
- 2001-01-17 AU AU2001232818A patent/AU2001232818A1/en not_active Abandoned
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