ATE392183T1 - Hydrophile zyaninfarbstoffe - Google Patents
Hydrophile zyaninfarbstoffeInfo
- Publication number
- ATE392183T1 ATE392183T1 AT01904882T AT01904882T ATE392183T1 AT E392183 T1 ATE392183 T1 AT E392183T1 AT 01904882 T AT01904882 T AT 01904882T AT 01904882 T AT01904882 T AT 01904882T AT E392183 T1 ATE392183 T1 AT E392183T1
- Authority
- AT
- Austria
- Prior art keywords
- therapy
- compounds
- imaging
- detection
- useful
- Prior art date
Links
- 239000000975 dye Substances 0.000 title abstract 5
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 title abstract 3
- 238000002560 therapeutic procedure Methods 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000002059 diagnostic imaging Methods 0.000 abstract 2
- 238000003384 imaging method Methods 0.000 abstract 2
- 230000005856 abnormality Effects 0.000 abstract 1
- 239000012867 bioactive agent Substances 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 229940077731 carbohydrate nutrients Drugs 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000012216 imaging agent Substances 0.000 abstract 1
- NFHFRUOZVGFOOS-UHFFFAOYSA-N palladium;triphenylphosphane Chemical compound [Pd].C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 NFHFRUOZVGFOOS-UHFFFAOYSA-N 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0056—Peptides, proteins, polyamino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/484,319 US6180086B1 (en) | 2000-01-18 | 2000-01-18 | Hydrophilic cyanine dyes |
| US09/757,332 US7011817B2 (en) | 2000-01-18 | 2001-01-09 | Hydrophilic cyanine dyes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE392183T1 true ATE392183T1 (de) | 2008-05-15 |
Family
ID=27047953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01904882T ATE392183T1 (de) | 2000-01-18 | 2001-01-17 | Hydrophile zyaninfarbstoffe |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1250091B1 (de) |
| JP (1) | JP2003529632A (de) |
| AT (1) | ATE392183T1 (de) |
| AU (1) | AU2001232818A1 (de) |
| WO (1) | WO2001052744A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7790144B2 (en) * | 2000-01-18 | 2010-09-07 | Mallinckrodt Inc. | Receptor-avid exogenous optical contrast and therapeutic agents |
| US6663847B1 (en) * | 2000-10-13 | 2003-12-16 | Mallinckrodt Inc. | Dynamic organ function monitoring agents |
| US6733744B1 (en) * | 2000-10-16 | 2004-05-11 | Mallinckrodt Inc. | Indole compounds as minimally invasive physiological function monitoring agents |
| US7556797B2 (en) | 2000-10-16 | 2009-07-07 | Mallinckrodt Inc. | Minimally invasive physiological function monitoring agents |
| US20030105299A1 (en) * | 2001-10-17 | 2003-06-05 | Mallinckrodt Inc. | Carbocyanine dyes for tandem, photodiagnostic and therapeutic applications |
| US20030105300A1 (en) * | 2001-10-17 | 2003-06-05 | Mallinckrodt Inc. | Tumor targeted photodiagnostic-phototherapeutic agents |
| US20030152577A1 (en) * | 2002-02-07 | 2003-08-14 | Mallinckrodt Inc. | Dye-bioconjugates for simultaneous optical diagnostic and therapeutic applications |
| US6919333B2 (en) * | 2002-11-12 | 2005-07-19 | Rutgers, The State University Of New Jersey | Bis-transition-metal-chelate probes |
| WO2003091689A2 (en) * | 2002-03-28 | 2003-11-06 | Rutgers, The State Of University Of New Jersey | Bis-transition-metal-chelate-probes |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8615995D0 (en) * | 1986-07-01 | 1986-08-06 | Glaxo Group Ltd | Veterinary preparations |
| DE3721850A1 (de) * | 1987-07-02 | 1989-01-12 | Bayer Ag | Indolin-carbocyaninfarbstoffe |
| JP3354975B2 (ja) * | 1992-10-06 | 2002-12-09 | イビデン株式会社 | 蛍光標識試薬および蛍光免疫測定法 |
| US5631364A (en) * | 1994-03-31 | 1997-05-20 | Axis Biochemicals Asa | Labelled boronic acid derivatives |
| EP0769145A1 (de) * | 1994-06-30 | 1997-04-23 | Biometric Imaging Inc. | Durch ein n-heteroaromatisches ion oder ein iminiumion substituierte cyaninfarbstoffe zur verwendung als fluoreszenzmarker |
| IT1276833B1 (it) * | 1995-10-09 | 1997-11-03 | Sorin Biomedica Cardio Spa | Coloranti fluorescenti della famiglia della solfo benz e indocianina |
| AU5651799A (en) * | 1998-09-17 | 2000-04-10 | Nippon Kayaku Kabushiki Kaisha | Remedies for photochemotherapy |
| JP4041613B2 (ja) * | 1999-03-12 | 2008-01-30 | 富士フイルム株式会社 | 画像形成材料 |
| DE19911102A1 (de) * | 1999-03-12 | 2000-09-14 | Few Chemicals Gmbh Wolfen | Cyanin-Farbstoffe |
| US6180086B1 (en) * | 2000-01-18 | 2001-01-30 | Mallinckrodt Inc. | Hydrophilic cyanine dyes |
-
2001
- 2001-01-17 AU AU2001232818A patent/AU2001232818A1/en not_active Abandoned
- 2001-01-17 WO PCT/US2001/001468 patent/WO2001052744A1/en active Application Filing
- 2001-01-17 JP JP2001552799A patent/JP2003529632A/ja active Pending
- 2001-01-17 AT AT01904882T patent/ATE392183T1/de not_active IP Right Cessation
- 2001-01-17 EP EP01904882A patent/EP1250091B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003529632A (ja) | 2003-10-07 |
| AU2001232818A1 (en) | 2001-07-31 |
| EP1250091B1 (de) | 2008-04-16 |
| EP1250091A4 (de) | 2003-05-07 |
| WO2001052744A1 (en) | 2001-07-26 |
| EP1250091A1 (de) | 2002-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |