JP2003500464A5 - - Google Patents

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Publication number
JP2003500464A5
JP2003500464A5 JP2000621320A JP2000621320A JP2003500464A5 JP 2003500464 A5 JP2003500464 A5 JP 2003500464A5 JP 2000621320 A JP2000621320 A JP 2000621320A JP 2000621320 A JP2000621320 A JP 2000621320A JP 2003500464 A5 JP2003500464 A5 JP 2003500464A5
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JP
Japan
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alkenyl
alkyl
compound
substituted
hydrogen
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JP2000621320A
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English (en)
Japanese (ja)
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JP5059996B2 (ja
JP2003500464A (ja
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Priority claimed from PCT/US2000/013202 external-priority patent/WO2000073253A1/en
Publication of JP2003500464A publication Critical patent/JP2003500464A/ja
Publication of JP2003500464A5 publication Critical patent/JP2003500464A5/ja
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Publication of JP5059996B2 publication Critical patent/JP5059996B2/ja
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JP2000621320A 1999-05-14 2000-05-12 新規インターロイキン−１および腫瘍壊死因子−αモジュレーター、前記モジュレーターの合成、ならびに前記モジュレーターの使用方法 Expired - Lifetime JP5059996B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13429599P 1999-05-14 1999-05-14
US60/134,295 1999-05-14
US18685300P 2000-03-03 2000-03-03
US60/186,853 2000-03-03
PCT/US2000/013202 WO2000073253A1 (en) 1999-05-14 2000-05-12 NOVEL INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR-α MODULATORS, SYNTHESES OF SAID MODULATORS AND METHODS OF USING SAID MODULATORS

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012137825A Division JP2012211162A (ja) 1999-05-14 2012-06-19 新規インターロイキン−１および腫瘍壊死因子−αモジュレーター、前記モジュレーターの合成、ならびに前記モジュレーターの使用方法

Publications (3)

Publication Number Publication Date
JP2003500464A JP2003500464A (ja) 2003-01-07
JP2003500464A5 true JP2003500464A5 (https=) 2007-07-05
JP5059996B2 JP5059996B2 (ja) 2012-10-31

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ID=26832188

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JP2000621320A Expired - Lifetime JP5059996B2 (ja) 1999-05-14 2000-05-12 新規インターロイキン−１および腫瘍壊死因子−αモジュレーター、前記モジュレーターの合成、ならびに前記モジュレーターの使用方法
JP2012137825A Withdrawn JP2012211162A (ja) 1999-05-14 2012-06-19 新規インターロイキン−１および腫瘍壊死因子−αモジュレーター、前記モジュレーターの合成、ならびに前記モジュレーターの使用方法

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JP2012137825A Withdrawn JP2012211162A (ja) 1999-05-14 2012-06-19 新規インターロイキン−１および腫瘍壊死因子−αモジュレーター、前記モジュレーターの合成、ならびに前記モジュレーターの使用方法

Country Status (17)

Country Link
US (3) US6365768B1 (https=)
EP (2) EP1591437B1 (https=)
JP (2) JP5059996B2 (https=)
KR (3) KR100856353B1 (https=)
CN (1) CN1361760A (https=)
AT (2) ATE449754T1 (https=)
AU (2) AU783372B2 (https=)
BR (1) BR0011522A (https=)
CA (1) CA2372962C (https=)
DE (2) DE60036101T2 (https=)
DK (1) DK1178952T5 (https=)
ES (2) ES2337264T3 (https=)
IL (3) IL146221A0 (https=)
MX (1) MXPA01011613A (https=)
NZ (3) NZ515675A (https=)
PT (2) PT1178952E (https=)
WO (1) WO2000073253A1 (https=)

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US7714012B2 (en) 2006-11-17 2010-05-11 Trustees Of Dartmouth University Synthesis and biological activities of new tricyclic-bis-enones (TBEs)
US8299046B2 (en) 2006-11-17 2012-10-30 Trustees Of Dartmouth College Synthetic triterpenoids and tricyclic-bis-enones for use in stimulating bone and cartilage growth
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US7875853B2 (en) * 2007-07-23 2011-01-25 Honeywell International Inc. Low-cost PIR scanning mechanism
PL2252283T3 (pl) 2008-01-11 2019-09-30 Reata Pharmaceuticals, Inc. Syntetyczne triterpenoidy i sposoby zastosowania w leczeniu choroby
CN102164941B (zh) 2008-04-18 2015-05-27 里亚塔医药公司 抗氧化剂炎症调节剂:具有饱和c环的齐墩果酸衍生物
WO2009146216A2 (en) 2008-04-18 2009-12-03 Reata Pharmaceuticals. Inc. Antioxidant inflammation modulators: novel derivatives of oleanolic acid
WO2009129546A1 (en) 2008-04-18 2009-10-22 Reata Pharmaceuticals, Inc. Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at c-17
RS55631B1 (sr) 2008-04-18 2017-06-30 Reata Pharmaceuticals Inc Antioksidansni modulatori upale: c-17 homologisani derivati oleanolinske kiseline
CA2721665C (en) 2008-04-18 2017-01-24 Reata Pharmaceuticals, Inc. Compounds including an anti-inflammatory pharmacore and methods of use
ES2449396T3 (es) 2008-07-22 2014-03-19 Trustees Of Dartmouth College Cianoenonas monocíclicas y métodos de uso de las mismas
US20110293653A1 (en) * 2010-03-11 2011-12-01 University Of Massachusetts Antagonists of mir-155 for the treatment of inflammatory liver disease
MX357596B (es) 2010-04-12 2018-07-16 Reata Pharmaceuticals Inc Método para tratar obesidad utilizando moduladores de inflamación con antioxidantes.
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WO2012078667A2 (en) * 2010-12-06 2012-06-14 The Penn State Research Foundation Compositions and methods relating to proliferative diseases
PL2651902T3 (pl) 2010-12-17 2018-04-30 Reata Pharmaceuticals, Inc. Pirazolilowe i pirymidynylowe tricykliczne enony jako modulatory zapalenia o działaniu przeciwutleniającym
SI2683731T1 (sl) 2011-03-11 2019-07-31 Reata Pharmaceuticals, Inc. C4-monometil triterpenoidni derivati in postopki njihove uporabe
JP6410710B2 (ja) 2012-04-27 2018-10-24 リアタ ファーマシューティカルズ インコーポレイテッド バルドキソロンメチルの２，２−ジフルオロプロピオンアミド誘導体、その多形体および使用方法
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WO2014040060A1 (en) 2012-09-10 2014-03-13 Reata Pharmaceuticals, Inc. C17-alkanediyl and alkenediyl derivatives of oleanolic acid and methods of use thereof
US9278912B2 (en) 2012-09-10 2016-03-08 Reata Pharmaceuticals, Inc. C13-hydroxy derivatives of oleanolic acid and methods of use thereof
BR112018005861B1 (pt) 2015-09-23 2022-11-22 Reata Pharmaceuticals, Inc Compostos derivados de ácido oleanólico modificado com c4 para a inibição de il-17, composição farmacêutica e usos terapêuticos dos ditos compostos
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