JP2002518321A5 - - Google Patents
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- Publication number
- JP2002518321A5 JP2002518321A5 JP2000554356A JP2000554356A JP2002518321A5 JP 2002518321 A5 JP2002518321 A5 JP 2002518321A5 JP 2000554356 A JP2000554356 A JP 2000554356A JP 2000554356 A JP2000554356 A JP 2000554356A JP 2002518321 A5 JP2002518321 A5 JP 2002518321A5
- Authority
- JP
- Japan
- Prior art keywords
- carrier
- vasodilator
- healthy humans
- atp
- enhanced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 description 8
- PQGCEDQWHSBAJP-TXICZTDVSA-N 5-O-phosphono-alpha-D-ribofuranosyl diphosphate Chemical compound O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O PQGCEDQWHSBAJP-TXICZTDVSA-N 0.000 description 6
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 6
- 239000003071 vasodilator agent Substances 0.000 description 6
- PYMYPHUHKUWMLA-LMVFSUKVSA-N aldehydo-D-ribose Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 5
- RPTUSVTUFVMDQK-UHFFFAOYSA-N Hidralazin Chemical compound C1=CC=C2C(NN)=NN=CC2=C1 RPTUSVTUFVMDQK-UHFFFAOYSA-N 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 230000002407 ATP formation Effects 0.000 description 3
- 101800000628 PDH precursor-related peptide Proteins 0.000 description 3
- 230000037147 athletic performance Effects 0.000 description 3
- 229960003624 creatine Drugs 0.000 description 3
- 239000006046 creatine Substances 0.000 description 3
- 208000037906 ischaemic injury Diseases 0.000 description 3
- 230000037081 physical activity Effects 0.000 description 3
- 210000002027 skeletal muscle Anatomy 0.000 description 3
- 229940124549 vasodilator Drugs 0.000 description 3
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 description 2
- 229930024421 Adenine Natural products 0.000 description 2
- 239000004475 Arginine Substances 0.000 description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 description 2
- 239000000006 Nitroglycerin Substances 0.000 description 2
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 2
- 229960000643 adenine Drugs 0.000 description 2
- GFFGJBXGBJISGV-UHFFFAOYSA-N adenyl group Chemical group N1=CN=C2N=CNC2=C1N GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 2
- 229960003121 arginine Drugs 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 229960003711 glyceryl trinitrate Drugs 0.000 description 2
- 229960002474 hydralazine Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229910052749 magnesium Inorganic materials 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 150000002972 pentoses Chemical class 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9000198P | 1998-06-19 | 1998-06-19 | |
| US60/090,001 | 1998-06-19 | ||
| US09/290,789 US6159942A (en) | 1998-06-19 | 1999-04-12 | Compositions for increasing energy in vivo |
| US09/290,789 | 1999-04-12 | ||
| PCT/US1999/013720 WO1999065476A2 (en) | 1998-06-19 | 1999-06-17 | COMPOSITIONS FOR INCREASING ENERGY $i(IN VIVO) |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010089732A Division JP2010168394A (ja) | 1998-06-19 | 2010-04-08 | エネルギーをインビボで増加させるための組成物 |
| JP2013162441A Division JP2013237697A (ja) | 1998-06-19 | 2013-08-05 | エネルギーをインビボで増加させるための組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002518321A JP2002518321A (ja) | 2002-06-25 |
| JP2002518321A5 true JP2002518321A5 (https=) | 2012-05-17 |
Family
ID=26781174
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000554356A Pending JP2002518321A (ja) | 1998-06-19 | 1999-06-17 | エネルギーをインビボで増加させるための組成物 |
| JP2010089732A Pending JP2010168394A (ja) | 1998-06-19 | 2010-04-08 | エネルギーをインビボで増加させるための組成物 |
| JP2013162441A Pending JP2013237697A (ja) | 1998-06-19 | 2013-08-05 | エネルギーをインビボで増加させるための組成物 |
| JP2013229436A Pending JP2014043453A (ja) | 1998-06-19 | 2013-11-05 | エネルギーをインビボで増加させるための組成物 |
| JP2016089312A Pending JP2016153421A (ja) | 1998-06-19 | 2016-04-27 | エネルギーをインビボで増加させるための組成物 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010089732A Pending JP2010168394A (ja) | 1998-06-19 | 2010-04-08 | エネルギーをインビボで増加させるための組成物 |
| JP2013162441A Pending JP2013237697A (ja) | 1998-06-19 | 2013-08-05 | エネルギーをインビボで増加させるための組成物 |
| JP2013229436A Pending JP2014043453A (ja) | 1998-06-19 | 2013-11-05 | エネルギーをインビボで増加させるための組成物 |
| JP2016089312A Pending JP2016153421A (ja) | 1998-06-19 | 2016-04-27 | エネルギーをインビボで増加させるための組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6159942A (https=) |
| EP (1) | EP1087779B1 (https=) |
| JP (5) | JP2002518321A (https=) |
| CN (1) | CN1306431A (https=) |
| AT (1) | ATE534393T1 (https=) |
| AU (1) | AU4575299A (https=) |
| CA (1) | CA2334415C (https=) |
| ES (1) | ES2374260T3 (https=) |
| NZ (1) | NZ508478A (https=) |
| WO (1) | WO1999065476A2 (https=) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020119933A1 (en) * | 2000-07-28 | 2002-08-29 | Butler Terri L. | Compositions and methods for improving cardiovascular function |
| US6511964B2 (en) | 1999-09-24 | 2003-01-28 | Bioenergy, Inc. | Method for treating acute mountain sickness |
| US6159943A (en) * | 1999-09-24 | 2000-12-12 | Bioenergy, Inc. | Use of ribose to prevent cramping and soreness in muscles |
| US6339716B1 (en) * | 1999-09-24 | 2002-01-15 | Bioenergy Inc. | Method for determining viability of a myocardial segment |
| US6703370B1 (en) * | 1999-10-27 | 2004-03-09 | Bioenergy, Inc. | Use of ribose to treat fibromyalgia |
| GB2353217B (en) * | 1999-10-27 | 2001-07-18 | Bioenergy Inc | Use of ribose to treat fibromyalgia |
| AU1800801A (en) * | 1999-11-17 | 2001-05-30 | Eric H. Kuhrts | Exercise and muscle enhancement formulations |
| DE10085291T1 (de) | 1999-12-21 | 2003-05-08 | Bioenergy Inc | Zusammensetzungen für die Lagerung von Blutplättchen |
| CA2397707A1 (en) * | 2000-01-07 | 2001-07-19 | Susan S. Percival | Compositions for enhancing the immune response |
| WO2001052831A1 (en) | 2000-01-20 | 2001-07-26 | Bioenergy Inc. | Use of ribose supplementation for increasing muscle mass and decreasing body fat in humans |
| US6553254B1 (en) * | 2000-04-07 | 2003-04-22 | Keith E. Kenyon | Combination of non-living-source physical energy and living-source chemical energy to maximize the salvage of ATP |
| US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
| US6420342B1 (en) | 2000-05-08 | 2002-07-16 | N.V. Nutricia | Nutritional preparation comprising ribose and medical use thereof |
| IT1317043B1 (it) * | 2000-06-14 | 2003-05-26 | Sigma Tau Healthscience Spa | Integratore alimentare potenziante il metabolismo energeticomuscolare, comprendente una alcanoil l-carnitina e ribosio. |
| CN1299690C (zh) * | 2000-07-28 | 2007-02-14 | 生物能量公司 | 用于提高心血管功能的组合物 |
| US6855727B2 (en) * | 2000-12-04 | 2005-02-15 | Yaizu Suisankagaku Industry Co., Ltd. | Muscular fatigue-controlling composition and method for providing muscular fatigue-controlling effect |
| EP1247525A1 (en) * | 2001-04-02 | 2002-10-09 | Bioenergy Inc. | Use of a monosaccharide in the manufacture of a medicament against acute mountain sickness |
| US7629329B2 (en) * | 2001-06-04 | 2009-12-08 | Tsi Health Sciences, Inc. | Method for increasing muscle mass and strength through administration of adenosine triphosphate |
| GB2381451A (en) * | 2001-11-01 | 2003-05-07 | New Technology Res Ltd | Pharmaco-dietary preparation having nutrition-supplementing and nutrition-enhancing effect |
| DE10215007A1 (de) * | 2002-04-05 | 2003-10-16 | Degussa Bioactives Deutschland | Verwendung von Kreatinpyruvat zur Steigerung der Ausdauer bei hochintensiven körperlichen Intervallbelastungen |
| US7547450B2 (en) * | 2002-10-24 | 2009-06-16 | Nestec Ltd. | Senior feline food |
| US6838562B2 (en) * | 2003-04-01 | 2005-01-04 | Sal Abraham | Process for preparing a creatine heterocyclic acid salt and method of use |
| US8759315B2 (en) * | 2003-05-14 | 2014-06-24 | Viacell, Llc | Methods for rejuvenating |
| US7687468B2 (en) * | 2003-05-14 | 2010-03-30 | Viacell, LLC. | Rejuvenation of stored blood |
| US20040229205A1 (en) * | 2003-05-16 | 2004-11-18 | Ericson Daniel G. | Compositions for the storage of platelets |
| BRPI0506485A (pt) * | 2004-01-14 | 2007-02-13 | Bioenergy Inc | método para reduzir o tempo de recuperação de um mamìfero submetido a uma anestesia geral, método para aumentar a recuperação de sepsia e uma composição adequada para administração intravenosa |
| JP4754484B2 (ja) * | 2004-03-18 | 2011-08-24 | 田辺三菱製薬株式会社 | うつ様症状改善剤 |
| JP2005336176A (ja) * | 2004-04-28 | 2005-12-08 | Tanabe Seiyaku Co Ltd | 肉体疲労改善剤 |
| EP1786436B1 (en) * | 2004-04-29 | 2012-11-14 | RiboCor, Inc. | Method for improving ventilatory efficiency |
| US20100099630A1 (en) * | 2004-04-29 | 2010-04-22 | Maccarter Dean J | Method for improving ventilatory efficiency |
| US7968138B2 (en) * | 2004-07-23 | 2011-06-28 | Arnold Nerenberg | Food sweetener |
| US20060029644A1 (en) * | 2004-08-06 | 2006-02-09 | Kenyon Keith E | In vitro biochemical reactions with free anhydrous D-ribose |
| WO2007001883A2 (en) * | 2005-06-20 | 2007-01-04 | Accera, Inc. | Method to reduce oxidative damage and improve mitochondrial efficiency |
| US7566463B2 (en) | 2006-05-03 | 2009-07-28 | C. B. Fleet Company | Oral rehydration compositions |
| US20080146579A1 (en) * | 2006-12-15 | 2008-06-19 | N.V. Nutricia | Treatment of patients with chronic pulmonary diseases and nutritional compositions therefore |
| CA2674717C (en) * | 2007-01-23 | 2015-10-13 | Bioenergy, Inc. | Use of d-ribose to treat cardiac arrhythmias |
| US20080312169A1 (en) * | 2007-03-20 | 2008-12-18 | Clarence Albert Johnson | Cosmetic use of D-ribose |
| US20090197819A1 (en) * | 2007-03-20 | 2009-08-06 | Clarence Albert Johnson | Compositions for improving and repairing skin |
| CN101356971B (zh) * | 2007-07-30 | 2012-11-07 | 石药集团中奇制药技术（石家庄）有限公司 | 一种用于抗疲劳耐缺氧的保健食品组合物 |
| CA2853992C (en) | 2007-07-31 | 2020-06-23 | Cerecin Inc. | Use of genomic testing and ketogenic compounds for treatment of reduced cognitive function |
| US20090061016A1 (en) * | 2007-09-05 | 2009-03-05 | Selzer Jonathan A | Seawater Based Dietary Supplement Product for Energy and Electrolyte Replacement |
| US20090232750A1 (en) * | 2008-03-13 | 2009-09-17 | St Cyr John A | Compositions for indoor tanning |
| EP2413942A1 (en) * | 2008-04-02 | 2012-02-08 | Bioenergy Inc. | Use of ribose in first response to acute myocardial infarction |
| ES2422596T3 (es) | 2008-05-16 | 2013-09-12 | Robert V Kasubick | Uso de ribosa en el tratamiento del síndrome de las piernas inquietas |
| AU2009266869B2 (en) | 2008-07-03 | 2016-07-07 | Cerecin Inc. | Monoglyceride of acetoacetate and derivatives for the treatment of neurological disorders |
| AU2009283215B2 (en) * | 2008-08-20 | 2014-12-04 | Bioenergy, Inc. | Use of D-ribose for fatigued subjects |
| IT1391588B1 (it) * | 2008-10-15 | 2012-01-11 | Giellepi Chemicals S P A | Composizione sinergica per il recupero e la riduzione del danno ischemico lieve |
| US8255453B2 (en) | 2009-09-14 | 2012-08-28 | International Business Machines Corporation | Public BOT management in private networks |
| US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| JP5823985B2 (ja) | 2010-02-16 | 2015-11-25 | ビアセル，リミティド ライアビリティ カンパニー | 赤血球を治療するためのアルギニン含有組成物および方法 |
| US20110229871A1 (en) * | 2010-02-16 | 2011-09-22 | Ericson Daniel G | Nucleoside-containing compositions and methods for treating red blood cells |
| CN102058045B (zh) * | 2010-10-26 | 2012-09-19 | 开平牵牛生化制药有限公司 | 一种用于补充人体能量和恢复疲劳的饮品 |
| JP6463361B2 (ja) | 2013-09-08 | 2019-01-30 | コディアック サイエンシーズ インコーポレイテッドＫｏｄｉａｋ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． | 第ｖｉｉｉ因子両性イオンポリマーコンジュゲート |
| CA2951567C (en) | 2014-06-12 | 2023-10-31 | Lonza, Inc. | Method for decreasing skeletal muscle damage and/or oxidative stress in mammals |
| CA2966628C (en) * | 2014-11-03 | 2023-08-29 | Bioenergy Life Science, Inc. | Use of d-ribose to enhance adaptation to physical stress |
| BR112018012410B1 (pt) | 2015-12-18 | 2022-12-20 | Lonza Consumer Health Inc | Composição para o aumento da síntese de proteína e/ou força funcional musculares em mamíferos |
| EP4241838A3 (en) | 2016-02-01 | 2023-12-20 | Bioenergy Life Science, Inc. | Use of ribose for treatment of subjects having congestive heart failure |
| CN108433106A (zh) * | 2017-11-07 | 2018-08-24 | 付少才 | 一种耐缺氧活性果糖粉(液)组合物 |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| WO2023135827A1 (ja) * | 2022-01-13 | 2023-07-20 | ＮｅＳＡ合同会社 | 神経変性疾患の進行遅延及び防御剤 |
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| JPS6049764A (ja) * | 1983-08-29 | 1985-03-19 | Ajinomoto Co Inc | 食品組成物 |
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| DE19650755A1 (de) * | 1996-12-06 | 1998-06-10 | Wolfgang Dr Pliml | Anwendung von Ribose zur Leistungssteigerung |
| GB9715340D0 (en) * | 1997-07-22 | 1997-09-24 | Cerestar Holding Bv | Beverages for enhanced physical performance |
-
1999
- 1999-04-12 US US09/290,789 patent/US6159942A/en not_active Expired - Lifetime
- 1999-06-17 WO PCT/US1999/013720 patent/WO1999065476A2/en not_active Ceased
- 1999-06-17 AT AT99928759T patent/ATE534393T1/de active
- 1999-06-17 NZ NZ508478A patent/NZ508478A/en unknown
- 1999-06-17 ES ES99928759T patent/ES2374260T3/es not_active Expired - Lifetime
- 1999-06-17 CA CA002334415A patent/CA2334415C/en not_active Expired - Lifetime
- 1999-06-17 JP JP2000554356A patent/JP2002518321A/ja active Pending
- 1999-06-17 EP EP99928759A patent/EP1087779B1/en not_active Expired - Lifetime
- 1999-06-17 CN CN99807560A patent/CN1306431A/zh active Pending
- 1999-06-17 AU AU45752/99A patent/AU4575299A/en not_active Abandoned
-
2010
- 2010-04-08 JP JP2010089732A patent/JP2010168394A/ja active Pending
-
2013
- 2013-08-05 JP JP2013162441A patent/JP2013237697A/ja active Pending
- 2013-11-05 JP JP2013229436A patent/JP2014043453A/ja active Pending
-
2016
- 2016-04-27 JP JP2016089312A patent/JP2016153421A/ja active Pending
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