JP2002511741A - 細胞のdnaに核酸を導入するためのdna系トランスポゾンシステム - Google Patents
細胞のdnaに核酸を導入するためのdna系トランスポゾンシステムInfo
- Publication number
- JP2002511741A JP2002511741A JP53972098A JP53972098A JP2002511741A JP 2002511741 A JP2002511741 A JP 2002511741A JP 53972098 A JP53972098 A JP 53972098A JP 53972098 A JP53972098 A JP 53972098A JP 2002511741 A JP2002511741 A JP 2002511741A
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- protein
- cell
- dna
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Mycology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4066497P | 1997-03-11 | 1997-03-11 | |
| US60/040,664 | 1997-03-11 | ||
| US5386897P | 1997-07-28 | 1997-07-28 | |
| US60/053,868 | 1997-07-28 | ||
| US6530397P | 1997-11-13 | 1997-11-13 | |
| US60/065,303 | 1997-11-13 | ||
| PCT/US1998/004687 WO1998040510A1 (en) | 1997-03-11 | 1998-03-11 | Dna-based transposon system for the introduction of nucleic acid into dna of a cell |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008140004A Division JP2008271981A (ja) | 1997-03-11 | 2008-05-28 | 細胞のdnaに核酸を導入するためのdna系トランスポゾンシステム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002511741A true JP2002511741A (ja) | 2002-04-16 |
| JP2002511741A5 JP2002511741A5 (https=) | 2005-11-10 |
Family
ID=27365765
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53972098A Withdrawn JP2002511741A (ja) | 1997-03-11 | 1998-03-11 | 細胞のdnaに核酸を導入するためのdna系トランスポゾンシステム |
| JP2008140004A Pending JP2008271981A (ja) | 1997-03-11 | 2008-05-28 | 細胞のdnaに核酸を導入するためのdna系トランスポゾンシステム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008140004A Pending JP2008271981A (ja) | 1997-03-11 | 2008-05-28 | 細胞のdnaに核酸を導入するためのdna系トランスポゾンシステム |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6489458B2 (https=) |
| EP (1) | EP0973928B1 (https=) |
| JP (2) | JP2002511741A (https=) |
| KR (1) | KR20000076157A (https=) |
| AT (1) | ATE466948T1 (https=) |
| AU (1) | AU745049B2 (https=) |
| CA (1) | CA2280997C (https=) |
| DE (1) | DE69841648D1 (https=) |
| DK (1) | DK0973928T3 (https=) |
| WO (1) | WO1998040510A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008271981A (ja) * | 1997-03-11 | 2008-11-13 | Regents Of The Univ Of Minnesota | 細胞のdnaに核酸を導入するためのdna系トランスポゾンシステム |
| JP2022093564A (ja) * | 2014-04-23 | 2022-06-23 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | キメラ抗原受容体(car)並びにその製造及び使用方法 |
Families Citing this family (238)
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| EP1034258A2 (en) * | 1997-11-13 | 2000-09-13 | The Regents Of The University Of Minnesota | Nucleic acid transfer vector for the introduction of nucleic acid into the dna of a cell |
| US7160682B2 (en) | 1998-11-13 | 2007-01-09 | Regents Of The University Of Minnesota | Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell |
| EP1155131B1 (en) * | 1999-02-19 | 2008-07-23 | ABT Holding Company | Vector comprising a splice acceptor trap and a poly a trap and the corresponding eukaryotic host cells |
| US6299850B1 (en) | 1999-03-16 | 2001-10-09 | The United States Of America As Represented By The Department Of Energy | Carbon activation process for increased surface accessibility in electrochemical capacitors |
| US6562624B2 (en) | 1999-03-17 | 2003-05-13 | Paradigm Genetics, Inc. | Methods and materials for the rapid and high volume production of a gene knock-out library in an organism |
| JP2002543792A (ja) * | 1999-05-11 | 2002-12-24 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | ベクターによるトランスポゾン配列の供給及び組込み |
| US7196244B1 (en) * | 1999-06-01 | 2007-03-27 | University Of Utah | Method of transposon-mediated mutagenesis in the nematode caenorhabditis elegans |
| WO2001029205A2 (en) * | 1999-10-19 | 2001-04-26 | Minos Biosystems Limited | Method for genetic manipulation |
| AU7900300A (en) * | 1999-10-26 | 2001-05-08 | Shanghai Bio Road Gene Development Ltd. | A novel polypeptide - human pogo transposase 14 and a polynucleotide encoding the same |
| AU1100201A (en) * | 1999-10-28 | 2001-05-08 | Board Of Trustees Of The Leland Stanford Junior University | Methods of in vivo gene transfer using a sleeping beauty transposon system |
| CN1300827A (zh) * | 1999-12-22 | 2001-06-27 | 上海博德基因开发有限公司 | 一种新的多肽—人水手转座酶19和编码这种多肽的多核苷酸 |
| JP2001231567A (ja) * | 2000-02-18 | 2001-08-28 | Inst Of Physical & Chemical Res | テロメア長の調節方法 |
| JP4751556B2 (ja) * | 2000-02-28 | 2011-08-17 | ジーンシーグス, インコーポレイテッド | ナノカプセルカプセル化システムおよび方法 |
| CA2407651C (en) * | 2000-04-27 | 2013-07-02 | Max-Delbruck-Centrum Fur Molekulare Medizin | Sleeping beauty, a transposon vector with a broad host range for the genetic transformation in vertebrates |
| WO2002086074A2 (en) * | 2001-04-20 | 2002-10-31 | Regents Of The University Of Minnesota | Compositions for delivery of compounds to cells and methods of use |
| EP1308516A1 (en) * | 2001-10-24 | 2003-05-07 | ADEREGEM (Association pour le Développement de la Recherche en Génétique Moléculaire | Site-directed recombinase fusion proteins and corresponding polynucleotides, vectors and kits, and their uses for site-directed DNA recombination |
| AU2003231048A1 (en) * | 2002-04-22 | 2003-11-03 | Regents Of The University Of Minnesota | Transposon system and methods of use |
| US7164056B2 (en) | 2002-05-03 | 2007-01-16 | Pioneer Hi-Bred International, Inc. | Gene targeting using replicating DNA molecules |
| DE10224242A1 (de) * | 2002-05-29 | 2003-12-11 | Max Delbrueck Centrum | Frog Prince, ein Transposonvektor für den Gentransfer bei Wirbeltieren |
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| US7985739B2 (en) | 2003-06-04 | 2011-07-26 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced sleeping beauty transposon system and methods for using the same |
| WO2005003359A1 (ja) * | 2003-07-08 | 2005-01-13 | Japan Science And Technology Corporation | トランスジェニック生物を作製する方法およびシステム |
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| DE102007048134A1 (de) * | 2007-10-05 | 2009-04-09 | Evocatal Gmbh | Verfahren und Gen-Kassetten zur Klonierung, Integration und Expression mehrerer Gene eines Genclusters |
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| WO1997015679A1 (en) | 1995-10-27 | 1997-05-01 | The Trustees Of The University Of Pennsylvania | Recombinant viruses containing mobile genetic elements and methods of use in gene therapy |
| JP2001503962A (ja) | 1996-02-09 | 2001-03-27 | ヘット ネーデルランツ カンケル インスティチュート | 細胞のゲノム中に組込まれる付加核酸物質を細胞に付与するためのベクターおよび方法 |
| US5948681A (en) | 1996-08-14 | 1999-09-07 | Children's Hospital Of Philadelphia | Non-viral vehicles for use in gene transfer |
| US5928888A (en) | 1996-09-26 | 1999-07-27 | Aurora Biosciences Corporation | Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and secondary screening capabilities |
| AU5588298A (en) | 1996-12-02 | 1998-06-29 | Cell Genesys, Inc. | Adeno-associated viral vector-mediated delivery of dna to cells of the liver |
| US6489458B2 (en) | 1997-03-11 | 2002-12-03 | Regents Of The University Of Minnesota | DNA-based transposon system for the introduction of nucleic acid into DNA of a cell |
| WO1998056903A1 (en) | 1997-06-13 | 1998-12-17 | President And Fellows Of Harvard College | Methods and uses for transposon-based gene targeting |
| EP1034258A2 (en) | 1997-11-13 | 2000-09-13 | The Regents Of The University Of Minnesota | Nucleic acid transfer vector for the introduction of nucleic acid into the dna of a cell |
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| AU1100201A (en) | 1999-10-28 | 2001-05-08 | Board Of Trustees Of The Leland Stanford Junior University | Methods of in vivo gene transfer using a sleeping beauty transposon system |
| CA2407651C (en) | 2000-04-27 | 2013-07-02 | Max-Delbruck-Centrum Fur Molekulare Medizin | Sleeping beauty, a transposon vector with a broad host range for the genetic transformation in vertebrates |
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| US7985739B2 (en) | 2003-06-04 | 2011-07-26 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced sleeping beauty transposon system and methods for using the same |
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1998
- 1998-03-11 US US09/142,593 patent/US6489458B2/en not_active Expired - Lifetime
- 1998-03-11 DK DK98910289.2T patent/DK0973928T3/da active
- 1998-03-11 EP EP98910289A patent/EP0973928B1/en not_active Expired - Lifetime
- 1998-03-11 WO PCT/US1998/004687 patent/WO1998040510A1/en not_active Ceased
- 1998-03-11 CA CA2280997A patent/CA2280997C/en not_active Expired - Lifetime
- 1998-03-11 AT AT98910289T patent/ATE466948T1/de not_active IP Right Cessation
- 1998-03-11 JP JP53972098A patent/JP2002511741A/ja not_active Withdrawn
- 1998-03-11 KR KR1019997008248A patent/KR20000076157A/ko not_active Withdrawn
- 1998-03-11 DE DE69841648T patent/DE69841648D1/de not_active Expired - Lifetime
- 1998-03-11 AU AU64569/98A patent/AU745049B2/en not_active Expired
-
2002
- 2002-10-02 US US10/263,159 patent/US7148203B2/en not_active Expired - Fee Related
-
2008
- 2008-05-28 JP JP2008140004A patent/JP2008271981A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008271981A (ja) * | 1997-03-11 | 2008-11-13 | Regents Of The Univ Of Minnesota | 細胞のdnaに核酸を導入するためのdna系トランスポゾンシステム |
| JP2022093564A (ja) * | 2014-04-23 | 2022-06-23 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | キメラ抗原受容体(car)並びにその製造及び使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20030124668A1 (en) | 2003-07-03 |
| CA2280997C (en) | 2013-05-28 |
| EP0973928A1 (en) | 2000-01-26 |
| WO1998040510A1 (en) | 1998-09-17 |
| JP2008271981A (ja) | 2008-11-13 |
| AU6456998A (en) | 1998-09-29 |
| DE69841648D1 (de) | 2010-06-17 |
| ATE466948T1 (de) | 2010-05-15 |
| KR20000076157A (ko) | 2000-12-26 |
| US7148203B2 (en) | 2006-12-12 |
| US6489458B2 (en) | 2002-12-03 |
| EP0973928B1 (en) | 2010-05-05 |
| CA2280997A1 (en) | 1998-09-17 |
| DK0973928T3 (da) | 2010-08-09 |
| AU745049B2 (en) | 2002-03-07 |
| US20020016975A1 (en) | 2002-02-07 |
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