CA2280997C - Dna-based transposon system for the introduction of nucleic acid into dna of a cell - Google Patents
Dna-based transposon system for the introduction of nucleic acid into dna of a cell Download PDFInfo
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- CA2280997C CA2280997C CA2280997A CA2280997A CA2280997C CA 2280997 C CA2280997 C CA 2280997C CA 2280997 A CA2280997 A CA 2280997A CA 2280997 A CA2280997 A CA 2280997A CA 2280997 C CA2280997 C CA 2280997C
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
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- Life Sciences & Earth Sciences (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
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Applications Claiming Priority (7)
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| US4066497P | 1997-03-11 | 1997-03-11 | |
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| US5386897P | 1997-07-28 | 1997-07-28 | |
| US60/053,868 | 1997-07-28 | ||
| US6530397P | 1997-11-13 | 1997-11-13 | |
| US60/065,303 | 1997-11-13 | ||
| PCT/US1998/004687 WO1998040510A1 (en) | 1997-03-11 | 1998-03-11 | Dna-based transposon system for the introduction of nucleic acid into dna of a cell |
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| CA2280997A1 CA2280997A1 (en) | 1998-09-17 |
| CA2280997C true CA2280997C (en) | 2013-05-28 |
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| DE (1) | DE69841648D1 (https=) |
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|---|---|---|---|---|
| US4631259A (en) | 1983-05-04 | 1986-12-23 | Board Of Regents Of The University Of Michigan | Transposon in cloning DNA |
| WO1988001646A1 (en) | 1986-08-26 | 1988-03-10 | Allelix Inc. | Universal system for transposon mutagenesis |
| FR2627508B1 (fr) | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
| EP0485701A1 (en) | 1990-09-28 | 1992-05-20 | American Cyanamid Company | Insertion of DNA by modified transposons |
| ES2121794T3 (es) | 1990-10-25 | 1998-12-16 | Clague Pitman Hodgson | Procedimiento de transferencia de genes por medio de retrotransposones. |
| WO1993004701A1 (en) | 1991-09-05 | 1993-03-18 | University Of Connecticut | Targeted delivery of poly- or oligonucleotides to cells |
| WO1993025239A1 (en) | 1992-06-17 | 1993-12-23 | Advanced Magnetics Inc. | Arabinogalactan derivatives and uses thereof |
| US6225121B1 (en) | 1992-09-14 | 2001-05-01 | Institute Of Molecular Biology And Biotechnology/Forth | Eukaryotic transposable element |
| US5866755A (en) | 1993-06-14 | 1999-02-02 | Basf Aktiengellschaft | Animals transgenic for a tetracycline-regulated transcriptional inhibitor |
| US5464758A (en) | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| US5814618A (en) | 1993-06-14 | 1998-09-29 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| US5589362A (en) | 1993-06-14 | 1996-12-31 | Basf Aktiengesellschaft | Tetracycline regulated transcriptional modulators with altered DNA binding specificities |
| WO1995001095A1 (en) | 1993-06-30 | 1995-01-12 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Transformed eukaryotic cells, and transposon-based transformation vectors |
| US5677170A (en) | 1994-03-02 | 1997-10-14 | The Johns Hopkins University | In vitro transposition of artificial transposons |
| FR2722506B1 (fr) | 1994-07-13 | 1996-08-14 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucleiques, preparation et utilisations |
| CA2180202A1 (en) | 1995-06-30 | 1996-12-31 | Mika Moriya | Method of amplifying gene using artificial transposon |
| WO1997015679A1 (en) | 1995-10-27 | 1997-05-01 | The Trustees Of The University Of Pennsylvania | Recombinant viruses containing mobile genetic elements and methods of use in gene therapy |
| JP2001503962A (ja) | 1996-02-09 | 2001-03-27 | ヘット ネーデルランツ カンケル インスティチュート | 細胞のゲノム中に組込まれる付加核酸物質を細胞に付与するためのベクターおよび方法 |
| US5948681A (en) | 1996-08-14 | 1999-09-07 | Children's Hospital Of Philadelphia | Non-viral vehicles for use in gene transfer |
| US5928888A (en) | 1996-09-26 | 1999-07-27 | Aurora Biosciences Corporation | Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and secondary screening capabilities |
| AU5588298A (en) | 1996-12-02 | 1998-06-29 | Cell Genesys, Inc. | Adeno-associated viral vector-mediated delivery of dna to cells of the liver |
| US6489458B2 (en) | 1997-03-11 | 2002-12-03 | Regents Of The University Of Minnesota | DNA-based transposon system for the introduction of nucleic acid into DNA of a cell |
| WO1998056903A1 (en) | 1997-06-13 | 1998-12-17 | President And Fellows Of Harvard College | Methods and uses for transposon-based gene targeting |
| EP1034258A2 (en) | 1997-11-13 | 2000-09-13 | The Regents Of The University Of Minnesota | Nucleic acid transfer vector for the introduction of nucleic acid into the dna of a cell |
| MXPA00011312A (es) | 1998-05-20 | 2003-04-22 | Expression Genetics Inc | Un vehiculo de gen polimerico de poli-l.lisina injertada con polietilenglicol con porcion de enfoque hepatocitos. |
| US6303362B1 (en) | 1998-11-19 | 2001-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Adenoviral vector and methods for making and using the same |
| JP2002543792A (ja) | 1999-05-11 | 2002-12-24 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | ベクターによるトランスポゾン配列の供給及び組込み |
| AU1100201A (en) | 1999-10-28 | 2001-05-08 | Board Of Trustees Of The Leland Stanford Junior University | Methods of in vivo gene transfer using a sleeping beauty transposon system |
| CA2407651C (en) | 2000-04-27 | 2013-07-02 | Max-Delbruck-Centrum Fur Molekulare Medizin | Sleeping beauty, a transposon vector with a broad host range for the genetic transformation in vertebrates |
| US20020115216A1 (en) | 2000-05-19 | 2002-08-22 | Steer Clifford J. | Composition for delivery of compounds to cells |
| AU2001265187A1 (en) | 2000-05-30 | 2001-12-11 | Baylor College Of Medicine | Chimeric viral vectors for gene therapy |
| JP2004267001A (ja) | 2000-08-16 | 2004-09-30 | Kansai Tlo Kk | トランスジェニック哺乳動物及びその作製方法並びにこれを用いた遺伝子機能の解明方法 |
| US7985739B2 (en) | 2003-06-04 | 2011-07-26 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced sleeping beauty transposon system and methods for using the same |
-
1998
- 1998-03-11 US US09/142,593 patent/US6489458B2/en not_active Expired - Lifetime
- 1998-03-11 DK DK98910289.2T patent/DK0973928T3/da active
- 1998-03-11 EP EP98910289A patent/EP0973928B1/en not_active Expired - Lifetime
- 1998-03-11 WO PCT/US1998/004687 patent/WO1998040510A1/en not_active Ceased
- 1998-03-11 CA CA2280997A patent/CA2280997C/en not_active Expired - Lifetime
- 1998-03-11 AT AT98910289T patent/ATE466948T1/de not_active IP Right Cessation
- 1998-03-11 JP JP53972098A patent/JP2002511741A/ja not_active Withdrawn
- 1998-03-11 KR KR1019997008248A patent/KR20000076157A/ko not_active Withdrawn
- 1998-03-11 DE DE69841648T patent/DE69841648D1/de not_active Expired - Lifetime
- 1998-03-11 AU AU64569/98A patent/AU745049B2/en not_active Expired
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2002
- 2002-10-02 US US10/263,159 patent/US7148203B2/en not_active Expired - Fee Related
-
2008
- 2008-05-28 JP JP2008140004A patent/JP2008271981A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20030124668A1 (en) | 2003-07-03 |
| EP0973928A1 (en) | 2000-01-26 |
| WO1998040510A1 (en) | 1998-09-17 |
| JP2008271981A (ja) | 2008-11-13 |
| AU6456998A (en) | 1998-09-29 |
| DE69841648D1 (de) | 2010-06-17 |
| ATE466948T1 (de) | 2010-05-15 |
| KR20000076157A (ko) | 2000-12-26 |
| US7148203B2 (en) | 2006-12-12 |
| US6489458B2 (en) | 2002-12-03 |
| EP0973928B1 (en) | 2010-05-05 |
| JP2002511741A (ja) | 2002-04-16 |
| CA2280997A1 (en) | 1998-09-17 |
| DK0973928T3 (da) | 2010-08-09 |
| AU745049B2 (en) | 2002-03-07 |
| US20020016975A1 (en) | 2002-02-07 |
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