JP2001512964A - 分化した胎仔および成体ドナー細胞による核移植 - Google Patents

分化した胎仔および成体ドナー細胞による核移植

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Publication number
JP2001512964A
JP2001512964A JP53095898A JP53095898A JP2001512964A JP 2001512964 A JP2001512964 A JP 2001512964A JP 53095898 A JP53095898 A JP 53095898A JP 53095898 A JP53095898 A JP 53095898A JP 2001512964 A JP2001512964 A JP 2001512964A
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cell
cells
disease
differentiated
cicm
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JP2001512964A5 (https=
Inventor
スティーヴン エル スティース
ホセ シーベリー
ジェームズ ローブル
ポール ゴルーク
デ リーオン エフ エイベル ポンセ
ディー ジョセフ ジェリー
Original Assignee
ユニヴァーシティー オヴ マサチューセッツ ア パブリック インスティテューション オヴ ハイアー エデュケイション オヴ ザ コモンウェルス オヴ マサチューセッツ
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25123802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2001512964(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ユニヴァーシティー オヴ マサチューセッツ ア パブリック インスティテューション オヴ ハイアー エデュケイション オヴ ザ コモンウェルス オヴ マサチューセッツ filed Critical ユニヴァーシティー オヴ マサチューセッツ ア パブリック インスティテューション オヴ ハイアー エデュケイション オヴ ザ コモンウェルス オヴ マサチューセッツ
Publication of JP2001512964A publication Critical patent/JP2001512964A/ja
Publication of JP2001512964A5 publication Critical patent/JP2001512964A5/ja
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
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    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8778—Swine embryos
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/101—Bovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/106—Primate
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

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  • Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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JP53095898A 1997-01-10 1998-01-05 分化した胎仔および成体ドナー細胞による核移植 Ceased JP2001512964A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/781,752 US5945577A (en) 1997-01-10 1997-01-10 Cloning using donor nuclei from proliferating somatic cells
US08/781,752 1997-01-10
PCT/US1998/000002 WO1998030683A2 (en) 1997-01-10 1998-01-05 Nuclear transfer with differentiated fetal and adult donor cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007084406A Division JP2007167078A (ja) 1997-01-10 2007-03-28 分化した胎仔および成体ドナー細胞による核移植

Publications (2)

Publication Number Publication Date
JP2001512964A true JP2001512964A (ja) 2001-08-28
JP2001512964A5 JP2001512964A5 (https=) 2006-01-05

Family

ID=25123802

Family Applications (2)

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JP53095898A Ceased JP2001512964A (ja) 1997-01-10 1998-01-05 分化した胎仔および成体ドナー細胞による核移植
JP2007084406A Pending JP2007167078A (ja) 1997-01-10 2007-03-28 分化した胎仔および成体ドナー細胞による核移植

Family Applications After (1)

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JP2007084406A Pending JP2007167078A (ja) 1997-01-10 2007-03-28 分化した胎仔および成体ドナー細胞による核移植

Country Status (13)

Country Link
US (4) US5945577A (https=)
EP (2) EP1015572B1 (https=)
JP (2) JP2001512964A (https=)
CN (1) CN1248288B (https=)
AT (1) ATE356203T1 (https=)
AU (1) AU742363C (https=)
BR (1) BR9806872A (https=)
CA (1) CA2277192C (https=)
DE (1) DE69837270T2 (https=)
ES (1) ES2284197T3 (https=)
IL (2) IL130829A0 (https=)
NZ (1) NZ336612A (https=)
WO (1) WO1998030683A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000512159A (ja) * 1998-01-16 2000-09-19 アグロバイオジェン ゲーエムベーハー 胎仔線維芽細胞による効率的な核移入
JP2002500864A (ja) * 1998-01-21 2002-01-15 ユニバーシティ・オブ・ハワイ 成体の体細胞核を再構成した被核除去卵母細胞からの動物の満期の成長
JP2006522609A (ja) * 2003-04-09 2006-10-05 マギー−ウイメンズ・ヘルス・コーポレイション 動物の体細胞核移植と関係する紡錘体欠損を修正するための方法
JPWO2016140353A1 (ja) * 2015-03-04 2018-01-25 株式会社医療実験用大動物供給事業準備会社 安定した表現型を示す疾患モデルブタおよびその作製方法

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GB9517779D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517780D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US20090092588A1 (en) * 1997-01-10 2009-04-09 University Of Massachusetts As Represented By Its Amherst Campus Cloned ungulate embryos and animals, use of cells, tissues and organs thereof for transplantation therapies including parkinson's disease
US6235969B1 (en) 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
US6215041B1 (en) * 1997-01-10 2001-04-10 University Of Mmassachusetts Cloning using donor nuclei from a non-quiesecent somatic cells
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
NZ337495A (en) * 1997-03-06 2001-06-29 Infigen Inc Bovine primordial germ cells and their use in cloning
US6011197A (en) 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
IL133786A0 (en) 1997-07-03 2001-04-30 Univ Massachusetts Cloning using donor nuclei from non-serum starved, differentiated cells
AU8587598A (en) * 1997-07-26 1999-02-16 Wisconsin Alumni Research Foundation Trans-species nuclear transfer
CA2324009A1 (en) * 1998-03-16 1999-09-23 Relag Pty Ltd. Porcine nuclear transfer
AUPP294898A0 (en) * 1998-04-15 1998-05-07 Monash University Method of nuclear transfer
GB9808325D0 (en) * 1998-04-20 1998-06-17 Ltr Ciz Di Associazione Italia Source of nuclei for nuclear transfer
GB9811859D0 (en) * 1998-06-02 1998-07-29 Biotech & Biolog Scien Res Biological manipulation
CA2340242A1 (en) * 1998-08-11 2000-02-24 Teruhiko Wakayama Method of performing transgenesis
AU3881499A (en) * 1998-09-01 2000-03-21 Wisconsin Alumni Research Foundation Primate embryonic stem cells with compatible histocompatibility genes
US6580017B1 (en) * 1998-11-02 2003-06-17 Genzyme Transgenics Corporation Methods of reconstructed goat embryo transfer
US6781030B1 (en) 1998-11-02 2004-08-24 Trustee Of Tufts College, Ballou Hall Methods for cloning mammals using telophase oocytes
US20030177513A1 (en) * 1998-11-02 2003-09-18 Yann Echelard Transgenic and cloned mammals
EP1127112B1 (en) * 1998-11-02 2007-03-21 Trustees Of Tufts College Methods for cloning animals
US6700037B2 (en) 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
US7531715B1 (en) 1999-01-13 2009-05-12 Ppl Therapeutics (Scotland) Double nuclear transfer method and results thereof
US20020012660A1 (en) * 1999-03-04 2002-01-31 Alan Colman Method of preparing a somatic cells for nuclear transfer
DK1159415T3 (da) * 1999-03-04 2010-05-03 Revivicor Inc Genetisk modifikation af somatiske celler og anvendelse deraf
EP1198169B1 (en) * 1999-05-06 2008-05-07 Stem Cell Sciences (Australia) Pty Ltd A process of cell reprogramming through production of a heterokaryon
WO2001000795A1 (en) * 1999-06-30 2001-01-04 Hwang, Woo-Suk A method for producing cloned cows
AU753209B2 (en) * 1999-06-30 2002-10-10 Seoul National University Industry Foundation Method for producing cloned tigers by employing inter-species nuclear transplantation technique
AU5577600A (en) * 1999-06-30 2001-01-31 Woo-Suk Hwang A method for producing human embryonic skin cells by employing an inter-species nuclear transplantation technique
US20050255596A1 (en) * 1999-09-07 2005-11-17 West Michael D Methods of repairing tandemly repeated DNA sequences and extending cell life-span nuclear transfer
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US20040180430A1 (en) * 1999-09-07 2004-09-16 West Michael D. Methods of restoring telomere length and extending cell lifespan using nuclear transfer
AU7372500A (en) * 1999-09-13 2001-04-17 University Of Massachusetts Cloning pigs using donor cells or nuclei from differentiated cells and production of pluripotent porcine.
WO2002064799A2 (en) 1999-09-28 2002-08-22 Transkaryotic Therapies, Inc. Optimized messenger rna
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WO2001029206A1 (en) * 1999-10-15 2001-04-26 Advanced Cell Technology, Inc. Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells
JP2003514516A (ja) 1999-10-28 2003-04-22 ユニバーシティ オブ マサチューセッツ 多能性細胞と細胞株の雌性発生的または雄性発生的産生および分化した細胞と組織を産生するためのその使用
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US7074983B2 (en) 1999-11-19 2006-07-11 Kirin Beer Kabushiki Kaisha Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin
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US7820878B2 (en) * 1999-11-19 2010-10-26 Kyowa Hakko Kirin Co., Ltd. Production of ungulates, preferably bovines that produce human immunoglobulins
KR100417566B1 (ko) * 1999-11-19 2004-02-05 한국생명공학연구원 체세포 핵치환 복제수정란의 대량생산방법
AU2766401A (en) * 2000-01-04 2001-07-16 University Of Connecticut, The Method for cloning animals with targetted genetic alterations by transfer of long-term cultured male or female somatic cell nuclei, comprising artificially-induced genetic alterations, to enucleated recipient cells
CA2396219A1 (en) 2000-01-04 2001-07-12 Xiangzhong Yang Oocyte vitrification technique
US20060174358A1 (en) * 2001-01-04 2006-08-03 Xiangzhong Yang Method for cloning animals with targetted genetic alterations by transfer of long-term cultured male or female somatic cell nuclei, comprising artificially-induced genetic alterations, to enucleated recipient cells
US6635802B1 (en) * 2000-01-10 2003-10-21 The Texas A&M University System Nuclear transfer using cells cultured in serum starvation media containing apoptosis inhibitors
GB0001401D0 (en) * 2000-01-22 2000-03-08 Univ Edinburgh Methods for amplifying genetic material and use thereof
ATE517990T1 (de) * 2000-03-15 2011-08-15 Univ Georgia Effektive kernumprogrammierung in säugetieren
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US20020010949A1 (en) 2002-01-24
US20050108785A1 (en) 2005-05-19
DE69837270T2 (de) 2008-01-24
CA2277192A1 (en) 1998-07-16
AU742363B2 (en) 2002-01-03
IL130829A (en) 2008-11-26
EP1808484A1 (en) 2007-07-18
ES2284197T3 (es) 2007-11-01
WO1998030683A2 (en) 1998-07-16
ATE356203T1 (de) 2007-03-15
WO1998030683A3 (en) 1998-09-17
EP1015572B1 (en) 2007-03-07
AU742363C (en) 2007-06-28
IL130829A0 (en) 2001-01-28
BR9806872A (pt) 2000-04-18
US5945577A (en) 1999-08-31
AU6014598A (en) 1998-08-03
CN1248288B (zh) 2011-11-09
CN1248288A (zh) 2000-03-22
US6235970B1 (en) 2001-05-22
DE69837270D1 (de) 2007-04-19
JP2007167078A (ja) 2007-07-05

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