AU8587598A - Trans-species nuclear transfer - Google Patents

Trans-species nuclear transfer

Info

Publication number
AU8587598A
AU8587598A AU85875/98A AU8587598A AU8587598A AU 8587598 A AU8587598 A AU 8587598A AU 85875/98 A AU85875/98 A AU 85875/98A AU 8587598 A AU8587598 A AU 8587598A AU 8587598 A AU8587598 A AU 8587598A
Authority
AU
Australia
Prior art keywords
trans
nuclear transfer
species nuclear
species
transfer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU85875/98A
Inventor
Tanja Dominko
Neal L. First
Maissam Mitalipoua
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of AU8587598A publication Critical patent/AU8587598A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU85875/98A 1997-07-26 1998-07-24 Trans-species nuclear transfer Abandoned AU8587598A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5310397P 1997-07-26 1997-07-26
US60053103 1997-07-26
PCT/US1998/015387 WO1999005266A2 (en) 1997-07-26 1998-07-24 Trans-species nuclear transfer

Publications (1)

Publication Number Publication Date
AU8587598A true AU8587598A (en) 1999-02-16

Family

ID=21981947

Family Applications (1)

Application Number Title Priority Date Filing Date
AU85875/98A Abandoned AU8587598A (en) 1997-07-26 1998-07-24 Trans-species nuclear transfer

Country Status (2)

Country Link
AU (1) AU8587598A (en)
WO (1) WO1999005266A2 (en)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
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GB9517780D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US7696404B2 (en) 1996-08-19 2010-04-13 Advanced Cell Technology, Inc. Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
JP2001500725A (en) * 1996-08-19 2001-01-23 ユニヴァーシティー オヴ マサチューセッツ Embryonic or stem cell-like cell lines produced by interspecies nuclear transfer
CN1299408A (en) * 1998-03-02 2001-06-13 马萨诸塞大学 Embryonic or stem-like cell links produced by cross-species nuclear transplantation
CA2324009A1 (en) * 1998-03-16 1999-09-23 Relag Pty Ltd. Porcine nuclear transfer
AU753207B2 (en) * 1999-06-30 2002-10-10 Seoul National University Industry Foundation Method for producing cloned cows
EP1117763A4 (en) * 1999-06-30 2004-12-01 Hwang Woo Suk Method for producing cloned tigers by employing inter-species nuclear transplantation technique
WO2001000650A1 (en) * 1999-06-30 2001-01-04 Advanced Cell Technology, Inc. Cytoplasmic transfer to de-differentiate recipient cells
EP1109890A4 (en) * 1999-06-30 2004-12-29 Hwang Woo Suk Method for producing human cloned embryos by employing inter-species nuclear transplantation technique
EP1214404A4 (en) * 1999-09-14 2003-09-03 Univ Massachusetts Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
EP1240318A4 (en) * 1999-12-20 2004-12-08 Univ Massachusetts Embryonic or stem-like cells produced by cross species nuclear transplantation
WO2003018767A2 (en) 2001-08-27 2003-03-06 Advanced Cell Technology, Inc. Trans-differentiation and re-differentiation of somatic cells and production of cells for cell therapies
CA2659945C (en) 2005-08-03 2014-12-16 Advanced Cell Technology, Inc. Improved methods of reprogramming animal somatic cells
US10865383B2 (en) 2011-07-12 2020-12-15 Lineage Cell Therapeutics, Inc. Methods and formulations for orthopedic cell therapy
AU2014253942B9 (en) 2013-04-16 2020-08-13 Regeneron Pharmaceuticals, Inc. Targeted modification of rat genome
DK3080279T3 (en) 2013-12-11 2018-11-05 Regeneron Pharma METHODS AND COMPOSITIONS FOR TARGETED MODIFICATION OF A GENOM
RU2725520C2 (en) 2013-12-11 2020-07-02 Регенерон Фармасьютикалс, Инк. Methods and compositions for genome targeted modification
KR102374379B1 (en) 2014-06-06 2022-03-17 리제너론 파마슈티칼스 인코포레이티드 Methods and compositions for modifying a targeted locus
SG11201610633QA (en) 2014-06-26 2017-01-27 Regeneron Pharma Methods and compositions for targeted genetic modifications and methods of use
KR102531016B1 (en) 2014-11-21 2023-05-10 리제너론 파마슈티칼스 인코포레이티드 METHODS AND COMPOSITIONS FOR TARGETED GENETIC MODIFICATION USING PAIRED GUIDE RNAs
CA2971213C (en) 2014-12-19 2023-09-26 Regeneron Pharmaceuticals, Inc. Methods and compositions for targeted genetic modification through single-step multiple targeting
KR102616160B1 (en) 2015-03-16 2023-12-22 리제너론 파마슈티칼스 인코포레이티드 Non-human animal exhibiting diminished upper and lower motor neuron function and sensory perception
US10285388B2 (en) 2015-05-29 2019-05-14 Regeneron Pharmaceuticals, Inc. Non-human animals having a disruption in a C9ORF72 locus
AU2017221425A1 (en) 2016-02-16 2018-08-23 Regeneron Pharmaceuticals, Inc. Non-human animals having a mutant kynureninase gene
RU2745563C2 (en) 2016-05-20 2021-03-29 Регенерон Фармасьютикалс, Инк. Ways to overcome immunological tolerance using multiple guide rnas
US10548302B2 (en) 2016-07-29 2020-02-04 Regeneron Pharmaceuticals, Inc. Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy
WO2018064600A1 (en) 2016-09-30 2018-04-05 Regeneron Pharmaceuticals, Inc. Non-human animals having a hexanucleotide repeat expansion in a c9orf72 locus
EP3585158B1 (en) 2017-02-27 2023-07-05 Regeneron Pharmaceuticals, Inc. Rodent models of retinoschisis
CA3066945A1 (en) 2017-06-27 2019-01-03 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a humanized asgr1 locus
SG11201911619YA (en) 2017-07-31 2020-01-30 Regeneron Pharma Assessment of crispr/cas-induced recombination with an exogenous donor nucleic acid in vivo
CN111182790A (en) 2017-07-31 2020-05-19 瑞泽恩制药公司 CRISPR reporter non-human animals and uses thereof
US11130999B2 (en) 2017-07-31 2021-09-28 Regeneron Pharmaceuticals, Inc. Cas-ready mouse embryonic stem cells and mice and uses thereof
AU2018338790B2 (en) 2017-09-29 2022-09-15 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a humanized TTR locus and methods of use
KR102444458B1 (en) 2017-11-10 2022-09-19 리제너론 파마슈티칼스 인코포레이티드 Non-Human Animals Containing the SLC30A8 Mutation and Methods of Use
IL274740B2 (en) 2017-11-30 2024-06-01 Regeneron Pharma Non-human animals comprising a humanized trkb locus
CN111885915B (en) 2018-03-19 2023-04-28 瑞泽恩制药公司 Transcription modulation of animals using CRISPR/CAS systems
JP7222075B2 (en) 2018-09-13 2023-02-14 リジェネロン・ファーマシューティカルズ・インコーポレイテッド Complement factor H gene knockout rats as a model of C3 glomerulopathy
WO2020131632A1 (en) 2018-12-20 2020-06-25 Regeneron Pharmaceuticals, Inc. Nuclease-mediated repeat expansion
CN114206108B (en) 2019-04-04 2023-09-29 瑞泽恩制药公司 Non-human animals comprising a humanized clotting factor 12 locus
WO2020247452A1 (en) 2019-06-04 2020-12-10 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a humanized ttr locus with a beta-slip mutation and methods of use
SG11202111256XA (en) 2019-06-07 2021-11-29 Regeneron Pharma Non-human animals comprising a humanized albumin locus
KR20220024134A (en) 2019-06-27 2022-03-03 리제너론 파마슈티칼스 인코포레이티드 Modeling of TDP-43 protein abnormalities
WO2021108363A1 (en) 2019-11-25 2021-06-03 Regeneron Pharmaceuticals, Inc. Crispr/cas-mediated upregulation of humanized ttr allele
AU2021212668A1 (en) 2020-01-28 2022-08-18 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a humanized PNPLA3 locus and methods of use
WO2021158883A1 (en) 2020-02-07 2021-08-12 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a humanized klkb1 locus and methods of use
WO2021195079A1 (en) 2020-03-23 2021-09-30 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a humanized ttr locus comprising a v30m mutation and methods of use
EP4171215A2 (en) 2020-06-26 2023-05-03 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a humanized ace2 locus
AU2022381205A1 (en) 2021-11-04 2024-03-28 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a modified cacng1 locus
CA3238939A1 (en) 2021-12-08 2023-06-15 Gaurang Patel Mutant myocilin disease model and uses thereof
WO2023122506A1 (en) 2021-12-20 2023-06-29 Regeneron Pharmaceuticals, Inc. Non-human animals comprising humanized ace2 and tmprss loci
CN113943712B (en) * 2021-12-20 2022-03-22 南京岚轩生物科技有限公司 Electrofusion buffer solution, preparation method thereof and electrofusion method
WO2023150798A1 (en) 2022-02-07 2023-08-10 Regeneron Pharmaceuticals, Inc. Compositions and methods for defining optimal treatment timeframes in lysosomal disease
US20230257432A1 (en) 2022-02-11 2023-08-17 Regeneron Pharmaceuticals, Inc. Compositions and methods for screening 4r tau targeting agents
WO2023235677A1 (en) 2022-05-31 2023-12-07 Regeneron Pharmaceuticals, Inc. Animal model of tdp-43 proteinopathy
WO2024026488A2 (en) 2022-07-29 2024-02-01 Regeneron Pharmaceuticals, Inc. Non-human animals comprising a modified transferrin receptor locus
WO2024031053A1 (en) 2022-08-05 2024-02-08 Regeneron Pharmaceuticals, Inc. Aggregation-resistant variants of tdp-43
US20240224964A9 (en) 2022-09-29 2024-07-11 Regeneron Pharmaceuticals, Inc. Correction of hepatosteatosis in humanized liver animals through restoration of il6/il6r/gp130 signaling in human hepatocytes
WO2024163650A1 (en) 2023-02-01 2024-08-08 Regeneron Pharmaceuticals, Inc. Animals comprising a modified klhdc7b locus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496720A (en) * 1993-02-10 1996-03-05 Susko-Parrish; Joan L. Parthenogenic oocyte activation
GB9517780D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
JP2001500725A (en) * 1996-08-19 2001-01-23 ユニヴァーシティー オヴ マサチューセッツ Embryonic or stem cell-like cell lines produced by interspecies nuclear transfer
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells

Also Published As

Publication number Publication date
WO1999005266A2 (en) 1999-02-04
WO1999005266A3 (en) 1999-04-15
WO1999005266B1 (en) 1999-09-23

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase