IT1261471B - Composizione farmaceutica per somministrazione rettale nel trattamentodi cefalea e relativo metodo di preparazione ed impiego. - Google Patents

Composizione farmaceutica per somministrazione rettale nel trattamentodi cefalea e relativo metodo di preparazione ed impiego.

Info

Publication number
IT1261471B
IT1261471B ITRM930286A ITRM930286A IT1261471B IT 1261471 B IT1261471 B IT 1261471B IT RM930286 A ITRM930286 A IT RM930286A IT RM930286 A ITRM930286 A IT RM930286A IT 1261471 B IT1261471 B IT 1261471B
Authority
IT
Italy
Prior art keywords
treatment
pharmaceutical composition
rectal administration
headache
preparation
Prior art date
Application number
ITRM930286A
Other languages
English (en)
Inventor
Isabelle Richard
Isabelle Thielemans
Original Assignee
Glaxo Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Sa filed Critical Glaxo Lab Sa
Publication of ITRM930286A0 publication Critical patent/ITRM930286A0/it
Publication of ITRM930286A1 publication Critical patent/ITRM930286A1/it
Application granted granted Critical
Publication of IT1261471B publication Critical patent/IT1261471B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

La invenzione si riferisce ad una composizione farmaceutica per somministrazione rettale comprendente un composto che agisce come agonista di recettore 5HTL-simile sotto forma di sua base libera o di un suo solvato fisiologicamente accettabile come ingrediente attivo, insieme con uno o più veicoli od eccipienti farmaceuticamente accettabili.Sono descritti anche metodi per la produzione di tali composizioni e per il loro impiego nel trattamento di dolore cefalico.
ITRM930286A 1992-05-07 1993-05-06 Composizione farmaceutica per somministrazione rettale nel trattamentodi cefalea e relativo metodo di preparazione ed impiego. IT1261471B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929209882A GB9209882D0 (en) 1992-05-07 1992-05-07 Compositions

Publications (3)

Publication Number Publication Date
ITRM930286A0 ITRM930286A0 (it) 1993-05-06
ITRM930286A1 ITRM930286A1 (it) 1994-11-06
IT1261471B true IT1261471B (it) 1996-05-23

Family

ID=10715158

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM930286A IT1261471B (it) 1992-05-07 1993-05-06 Composizione farmaceutica per somministrazione rettale nel trattamentodi cefalea e relativo metodo di preparazione ed impiego.

Country Status (33)

Country Link
US (1) US5705506A (it)
EP (1) EP0639072B1 (it)
JP (1) JPH07506570A (it)
KR (1) KR100253111B1 (it)
AT (1) ATE163850T1 (it)
AU (1) AU670083B2 (it)
BE (1) BE1007024A5 (it)
BG (1) BG62120B1 (it)
BR (1) BR1100108A (it)
CA (1) CA2135179C (it)
CH (1) CH685920A5 (it)
CY (1) CY2039B1 (it)
CZ (1) CZ283512B6 (it)
DE (1) DE69317418T2 (it)
ES (1) ES2113533T3 (it)
FR (1) FR2690847B1 (it)
GB (2) GB9209882D0 (it)
GR (1) GR3026584T3 (it)
HK (1) HK95697A (it)
HU (2) HU227338B1 (it)
IE (1) IE75203B1 (it)
IL (1) IL105468A (it)
IT (1) IT1261471B (it)
NO (1) NO306700B1 (it)
NZ (1) NZ252132A (it)
OA (1) OA10109A (it)
RO (1) RO112993B1 (it)
RU (1) RU2118527C1 (it)
SG (1) SG46649A1 (it)
TW (1) TW231970B (it)
UA (1) UA37206C2 (it)
WO (1) WO1993021916A1 (it)
ZA (1) ZA933178B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2434297A (en) * 1996-05-23 1997-12-09 Alcon Laboratories, Inc. The use of 5-ht1b/1d agonists to treat ocular pain
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
ES2367294T3 (es) * 1998-03-26 2011-11-02 Astellas Pharma Inc. Preparación de liberación sostenida de un compuesto macrólido como tacrolimus.
WO2000051624A2 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Methods and compositions useful in inhibiting apoptosis
PL2124556T3 (pl) 2006-10-09 2015-02-27 Charleston Laboratories Inc Kompozycje farmaceutyczne
JP5714910B2 (ja) 2008-01-09 2015-05-07 チャールストン ラボラトリーズ,インコーポレイテッド 薬学的組成物
WO2011006012A1 (en) 2009-07-08 2011-01-13 Charleston Laboratories Inc. Pharmaceutical compositions
KR101825972B1 (ko) 2010-10-15 2018-02-06 콘테라 파르마 에이피에스 운동 장애 치료를 위한 세로토닌 수용체 작용제의 조합
US10561618B2 (en) 2012-04-18 2020-02-18 Contera Pharma Aps Orally available pharmaceutical formulation suitable for improved management of movement disorders
JP2019507181A (ja) 2016-03-04 2019-03-14 チャールストン ラボラトリーズ,インコーポレイテッド 医薬組成物
KR102443161B1 (ko) 2016-07-11 2022-09-14 콘테라 파르마 에이/에스 아침 운동 불능을 치료하기 위한 박동성 약물 전달 시스템

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1171450B (it) * 1980-08-12 1987-06-10 Glaxo Group Ltd Composti eterociclici indolici, procedimento per produrli e composizioni farmaceutiche che li contengono
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
GR79215B (it) * 1982-06-07 1984-10-22 Glaxo Group Ltd
GB8332435D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
FR2574077A1 (fr) * 1984-12-04 1986-06-06 Glaxo Group Ltd Derives d'indoles, leur preparation et les compositions pharmaceutiques les contenant
GB8431426D0 (en) * 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds
DE3678805D1 (de) * 1985-11-08 1991-05-23 Glaxo Group Ltd Indolderivate.
PT88255B (pt) * 1987-08-13 1995-03-01 Glaxo Group Ltd Processo para a preparacao de derivados do indole
PT97888B (pt) * 1990-06-07 1998-12-31 Zeneca Ltd Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem

Also Published As

Publication number Publication date
US5705506A (en) 1998-01-06
BG62120B1 (bg) 1999-03-31
BE1007024A5 (fr) 1995-02-21
NZ252132A (en) 1996-09-25
IE75203B1 (en) 1997-08-27
NO306700B1 (no) 1999-12-13
GB2266665A (en) 1993-11-10
FR2690847B1 (fr) 1995-06-09
RO112993B1 (ro) 1998-03-30
ITRM930286A1 (it) 1994-11-06
CZ283512B6 (cs) 1998-04-15
NO944214L (no) 1994-11-07
DE69317418D1 (de) 1998-04-16
CY2039B1 (en) 1998-04-30
HUT71418A (en) 1995-11-28
AU670083B2 (en) 1996-07-04
OA10109A (en) 1996-12-18
HU227338B1 (en) 2011-04-28
CA2135179A1 (en) 1993-11-11
BG99167A (bg) 1995-06-30
EP0639072A1 (en) 1995-02-22
SG46649A1 (en) 1998-02-20
FR2690847A1 (fr) 1993-11-12
HU211638A9 (en) 1995-12-28
TW231970B (it) 1994-10-11
GB9209882D0 (en) 1992-06-24
GR3026584T3 (en) 1998-07-31
RU2118527C1 (ru) 1998-09-10
JPH07506570A (ja) 1995-07-20
EP0639072B1 (en) 1998-03-11
BR1100108A (pt) 1999-12-07
ATE163850T1 (de) 1998-03-15
IE930339A1 (en) 1993-11-17
CA2135179C (en) 2000-12-05
ITRM930286A0 (it) 1993-05-06
WO1993021916A1 (en) 1993-11-11
ES2113533T3 (es) 1998-05-01
CH685920A5 (fr) 1995-11-15
IL105468A0 (en) 1993-08-18
CZ272394A3 (en) 1995-10-18
NO944214D0 (no) 1994-11-04
DE69317418T2 (de) 1998-07-30
UA37206C2 (uk) 2001-05-15
ZA933178B (en) 1994-01-10
GB2266665B (en) 1996-05-22
HK95697A (en) 1997-08-08
AU4064093A (en) 1993-11-29
KR100253111B1 (en) 2000-07-01
IL105468A (en) 1998-09-24
GB9309209D0 (en) 1993-06-16

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970530