IT1241460B - Formulazioni a cessione protratta di peptidi idrosolubili (caso 600-7110) - Google Patents

Formulazioni a cessione protratta di peptidi idrosolubili (caso 600-7110)

Info

Publication number
IT1241460B
IT1241460B IT48113A IT4811390A IT1241460B IT 1241460 B IT1241460 B IT 1241460B IT 48113 A IT48113 A IT 48113A IT 4811390 A IT4811390 A IT 4811390A IT 1241460 B IT1241460 B IT 1241460B
Authority
IT
Italy
Prior art keywords
protract
sale
formulations
case
water soluble
Prior art date
Application number
IT48113A
Other languages
English (en)
Italian (it)
Other versions
IT9048113A0 (it
IT9048113A1 (it
Inventor
David Bodmer
Jones W Fong
Thomas Kissel
Hawkins V Maulding
Oskar Nagele
Jane E Pearson
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT9048113A0 publication Critical patent/IT9048113A0/it
Publication of IT9048113A1 publication Critical patent/IT9048113A1/it
Application granted granted Critical
Publication of IT1241460B publication Critical patent/IT1241460B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT48113A 1989-07-07 1990-07-05 Formulazioni a cessione protratta di peptidi idrosolubili (caso 600-7110) IT1241460B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37702389A 1989-07-07 1989-07-07
US41134789A 1989-09-22 1989-09-22

Publications (3)

Publication Number Publication Date
IT9048113A0 IT9048113A0 (it) 1990-07-05
IT9048113A1 IT9048113A1 (it) 1992-01-05
IT1241460B true IT1241460B (it) 1994-01-17

Family

ID=27007654

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48113A IT1241460B (it) 1989-07-07 1990-07-05 Formulazioni a cessione protratta di peptidi idrosolubili (caso 600-7110)

Country Status (27)

Country Link
JP (5) JPH0832624B2 (da)
KR (2) KR100303681B1 (da)
AT (1) AT406225B (da)
AU (2) AU641407B2 (da)
BE (1) BE1004486A3 (da)
CA (1) CA2020477C (da)
CH (1) CH685230A5 (da)
CY (1) CY1965A (da)
DE (2) DE4021517B4 (da)
DK (1) DK175849B1 (da)
FI (3) FI108611B (da)
FR (1) FR2649319A1 (da)
GB (2) GB2234896B (da)
GR (1) GR1001121B (da)
HK (2) HK97695A (da)
HU (2) HU221294B1 (da)
IE (2) IE64216B1 (da)
IL (3) IL131881A (da)
IT (1) IT1241460B (da)
LU (1) LU87764A1 (da)
MY (1) MY106722A (da)
NL (1) NL195027C (da)
NO (2) NO302928B1 (da)
NZ (1) NZ234384A (da)
PT (1) PT94628B (da)
SE (1) SE512992C2 (da)
SG (1) SG26416G (da)

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CA2123144A1 (en) * 1993-05-10 1994-11-11 David Bodmer Stabilisation of pharmacologically active compounds in sustained release compositions
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US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
DE69608122T3 (de) 1995-11-09 2011-06-16 Microbiological Research Authority Camr, Salisbury Mikroverkapselte dna zur impfung und gentherapie
DE19545257A1 (de) 1995-11-24 1997-06-19 Schering Ag Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln
US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
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US6461631B1 (en) * 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
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US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
CA2432900C (en) 2000-12-21 2007-09-11 Nektar Therapeutics Induced phase transition method for the production of microparticles containing hydrophilic active agents
US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
PE20050285A1 (es) * 2003-06-24 2005-06-09 Novartis Ag Composicion farmaceutica que comprende analogos ciclicos de somatostatina
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EP1719523A4 (en) * 2004-02-26 2009-07-15 Japan Science & Tech Agency MICROPARTICULAR PROTEIN CARBIDE RETARD PREPARATION FOR INJECTION AND METHOD FOR THE PRODUCTION THEREOF
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KR100741867B1 (ko) * 2005-07-05 2007-07-24 전북대학교산학협력단 수중유적 및 용매 증발법을 이용한 이중층 미립구의제조방법
ES2492641T3 (es) * 2005-12-22 2014-09-10 Novartis Ag Formulación de liberación sostenida que comprende octreótida y dos o más polímeros de poliláctida-co-glicólido
KR100816065B1 (ko) 2006-11-27 2008-03-24 동국제약 주식회사 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐
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Also Published As

Publication number Publication date
GB2265311B (en) 1994-02-09
IT9048113A0 (it) 1990-07-05
HU903974D0 (en) 1990-11-28
NO983923D0 (no) 1998-08-26
LU87764A1 (fr) 1992-03-11
FI20000059A (fi) 2000-01-12
NL195027B (nl) 2003-08-01
GB2234896A (en) 1991-02-20
DK162590A (da) 1991-01-08
FR2649319A1 (fr) 1991-01-11
NO903001D0 (no) 1990-07-05
KR100303681B1 (ko) 2002-05-16
NL195027C (nl) 2003-12-02
AU641407B2 (en) 1993-09-23
NO983923L (no) 1991-01-08
GB2234896B (en) 1994-01-19
GB9014704D0 (en) 1990-08-22
IT9048113A1 (it) 1992-01-05
CA2020477A1 (en) 1991-01-08
GR1001121B (el) 1993-04-28
NO903001L (no) 1991-01-08
CA2020477C (en) 2000-11-21
PT94628A (pt) 1991-03-20
NL9001537A (nl) 1991-02-01
FI109543B (fi) 2002-08-30
NO302928B1 (no) 1998-05-11
HU211602A9 (en) 1995-12-28
AU2332195A (en) 1995-09-07
CH685230A5 (de) 1995-05-15
IL131880A (en) 2001-12-23
PT94628B (pt) 1997-06-30
NZ234384A (en) 1994-05-26
HK97695A (en) 1995-06-23
DE4021517B4 (de) 2009-04-09
MY106722A (en) 1995-07-31
GB9306204D0 (en) 1993-05-19
FR2649319B1 (da) 1994-12-09
SE9002364L (sv) 1991-01-08
HK197496A (en) 1996-11-08
HUT54037A (en) 1991-01-28
GR900100513A (en) 1991-12-10
KR100442931B1 (ko) 2004-08-02
KR910002430A (ko) 1991-02-25
ATA144090A (de) 1999-08-15
CY1965A (en) 1997-07-04
SG26416G (en) 1995-09-01
HU221294B1 (en) 2002-09-28
IE64411B1 (en) 1995-08-09
SE9002364D0 (sv) 1990-07-05
DE4042752B4 (de) 2009-05-07
JPH07309897A (ja) 1995-11-28
JP2001233897A (ja) 2001-08-28
SE512992C2 (sv) 2000-06-12
DK175849B1 (da) 2005-03-29
IE902435A1 (en) 1991-02-13
FI903429A0 (fi) 1990-07-06
GB2265311A (en) 1993-09-29
DK162590D0 (da) 1990-07-05
FI109334B (fi) 2002-07-15
FI20000060A (fi) 2000-01-12
JP2931773B2 (ja) 1999-08-09
IL94983A0 (en) 1991-06-10
AT406225B (de) 2000-03-27
AU687553B2 (en) 1998-02-26
BE1004486A3 (fr) 1992-12-01
NO320444B1 (no) 2005-12-05
JPH0832624B2 (ja) 1996-03-29
IL94983A (en) 1999-08-17
FI108611B (fi) 2002-02-28
DE4021517A1 (de) 1991-01-17
IE64216B1 (en) 1995-07-26
IL131881A (en) 2001-12-23
JPH07285853A (ja) 1995-10-31
AU5874690A (en) 1991-01-10
JPH08198771A (ja) 1996-08-06
JPH0368511A (ja) 1991-03-25

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BR9006934A (pt) Formulacoes aquosas estabilizadas de pequenos peptidios
DK111489D0 (da) Peptider
DK375789A (da) Peptidderivater
PT87350A (pt) Peptide mit phospholipase a2-hemmender wirkung
DK183090A (da) Renininhiberende peptid
DK197989A (da) Peptidanaloger
DK380288D0 (da) Hidtil ukendet peptider
DK301889D0 (da) Peptidderivater
FI930022A0 (fi) Kemiskt foerfarande
KR900700503A (ko) 펩티드
DK177789D0 (da) Peptidderivater
BR8907638A (pt) Preparados de fiacao contendo poliuretano
NO177858C (no) Peptid
FI925259A0 (fi) Kemiskt foerfarande
FI101474B1 (fi) Peptidisynteesi kiinteässä faasissa
KR900701833A (ko) 맥관형성 인자를 조력하는 맥관형성 조력 펩타이드(angiogenic potentiationg peptide)
SE8802429D0 (sv) Peptide analogues
DK154191A (da) Peptidpiller

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