IT1230441B - Eteri della serie dell'indazolo - Google Patents

Eteri della serie dell'indazolo

Info

Publication number
IT1230441B
IT1230441B IT8947620A IT4762089A IT1230441B IT 1230441 B IT1230441 B IT 1230441B IT 8947620 A IT8947620 A IT 8947620A IT 4762089 A IT4762089 A IT 4762089A IT 1230441 B IT1230441 B IT 1230441B
Authority
IT
Italy
Prior art keywords
ethers
indazole
series
indazole series
Prior art date
Application number
IT8947620A
Other languages
English (en)
Italian (it)
Other versions
IT8947620A0 (it
Inventor
Bruno Silvestrini
Leandro Baiocchi
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Priority to IT8947620A priority Critical patent/IT1230441B/it
Publication of IT8947620A0 publication Critical patent/IT8947620A0/it
Priority to IL9313290A priority patent/IL93132A/en
Priority to ES90200167T priority patent/ES2020171T3/es
Priority to EP90200167A priority patent/EP0382276B1/en
Priority to DE69021902T priority patent/DE69021902T2/de
Priority to DE199090200167T priority patent/DE382276T1/de
Priority to AT90200167T priority patent/ATE127115T1/de
Priority to DK90200167.6T priority patent/DK0382276T3/da
Priority to US07/470,118 priority patent/US4999367A/en
Priority to NZ232258A priority patent/NZ232258A/en
Priority to ZA90644A priority patent/ZA90644B/xx
Priority to PE1990164654A priority patent/PE25091A1/es
Priority to IN81/CAL/90A priority patent/IN170957B/en
Priority to AU49066/90A priority patent/AU624895B2/en
Priority to PL90283638A priority patent/PL163720B1/pl
Priority to YU20690A priority patent/YU47943B/sh
Priority to PL90285287A priority patent/PL163730B1/pl
Priority to RO144074A priority patent/RO106252B1/ro
Priority to SI9010206A priority patent/SI9010206A/sl
Priority to AR90316095A priority patent/AR247386A1/es
Priority to FI900577A priority patent/FI102678B/sv
Priority to BG091122A priority patent/BG50273A3/xx
Priority to CS90563A priority patent/CZ280121B6/cs
Priority to BG093295A priority patent/BG50274A3/xx
Priority to UA4743128A priority patent/UA26852C2/uk
Priority to PT93067A priority patent/PT93067B/pt
Priority to HU90689A priority patent/HU204793B/hu
Priority to BG093291A priority patent/BG51352A3/xx
Priority to SU904743128A priority patent/RU2066318C1/ru
Priority to PH40002A priority patent/PH26552A/en
Priority to BG093296A priority patent/BG50275A3/xx
Priority to JP2027007A priority patent/JP2870925B2/ja
Priority to EG6290A priority patent/EG19170A/xx
Priority to SK563-90A priority patent/SK278441B6/sk
Priority to DD90342349A priority patent/DD295363A5/de
Priority to KR1019900001453A priority patent/KR0145525B1/ko
Priority to DD90337657A priority patent/DD291995A5/de
Priority to CA002009503A priority patent/CA2009503C/en
Priority to CN90100599A priority patent/CN1046505C/zh
Priority to US07/632,117 priority patent/US5112986A/en
Priority to SU914895540A priority patent/RU2044729C1/ru
Priority to SU914895526A priority patent/RU2055071C1/ru
Application granted granted Critical
Publication of IT1230441B publication Critical patent/IT1230441B/it
Priority to GR91300073T priority patent/GR910300073T1/el
Priority to LVP-93-647A priority patent/LV10612B/lv
Priority to GEAP19931214A priority patent/GEP19971030B/en
Priority to LTIP872A priority patent/LT3604B/lt
Priority to CN93117740A priority patent/CN1034016C/zh
Priority to HRP-206/90A priority patent/HRP940878B1/xx
Priority to MD95-0055A priority patent/MD355C2/ro
Priority to GR950403284T priority patent/GR3018165T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IT8947620A 1989-02-07 1989-02-07 Eteri della serie dell'indazolo IT1230441B (it)

Priority Applications (50)

Application Number Priority Date Filing Date Title
IT8947620A IT1230441B (it) 1989-02-07 1989-02-07 Eteri della serie dell'indazolo
IL9313290A IL93132A (en) 1989-02-07 1990-01-22 History of N- (2) -benzylindazole-3-ilmethoxy (alkanoic acid, process for their preparation and pharmaceutical preparations containing them)
ES90200167T ES2020171T3 (es) 1989-02-07 1990-01-23 Eteres de 1-bencil-3-hidroximetilindazol con 2-hidroxiacidos alifaticos.
EP90200167A EP0382276B1 (en) 1989-02-07 1990-01-23 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids
DE69021902T DE69021902T2 (de) 1989-02-07 1990-01-23 1-Benzyl-3-hydroxymethylindazol-Äther mit aliphatischen 2-Hydroxysäuren.
DE199090200167T DE382276T1 (de) 1989-02-07 1990-01-23 1-benzyl-3-hydroxymethylindazol-aether mit aliphatischen 2-hydroxysaeuren.
AT90200167T ATE127115T1 (de) 1989-02-07 1990-01-23 1-benzyl-3-hydroxymethylindazol-äther mit aliphatischen 2-hydroxysäuren.
DK90200167.6T DK0382276T3 (da) 1989-02-07 1990-01-23 Ethere af 1-benzyl-3-hydroxymethyl-indazol med alifatiske 2-hydroxysyrer
US07/470,118 US4999367A (en) 1989-02-07 1990-01-24 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids, compositions and use
NZ232258A NZ232258A (en) 1989-02-07 1990-01-26 1-benzyl-indazol-3-yl methoxy acetic acid derivatives; preparatory processes pharmaceutical compositions and intermediates
ZA90644A ZA90644B (en) 1989-02-07 1990-01-29 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids
PE1990164654A PE25091A1 (es) 1989-02-07 1990-01-30 Eteres de 1-bencil-3-hidroximetil-indazol con 2-hidroxiacidos alifaticos
IN81/CAL/90A IN170957B (sv) 1989-02-07 1990-01-30
AU49066/90A AU624895B2 (en) 1989-02-07 1990-02-02 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids
PL90283638A PL163720B1 (pl) 1989-02-07 1990-02-05 Sposób wytwarzania nowych eterowych pochodnych 1-benzylo-3-hydroksymetyloindazolu PL PL PL PL PL PL PL PL
YU20690A YU47943B (sh) 1989-02-07 1990-02-05 Etri 1-benzil-3-hidroksimetil-indazola sa alifatičnim 2-hidroksi kiselinama i postupak dobijanja
PL90285287A PL163730B1 (pl) 1989-02-07 1990-02-05 Sposób wytwarzania 1 -benzylo-3-hydroksymetylo-Indazolu PL PL PL PL PL PL PL PL
RO144074A RO106252B1 (ro) 1989-02-07 1990-02-05 Derivati de eteri de indazol, procedee si intermediari pentru prepararea lor
SI9010206A SI9010206A (sl) 1989-02-07 1990-02-05 Etri 1-benzil-3-hidroksimetil-indazola z alifatskimi 2-hidroksi kislinami
AR90316095A AR247386A1 (es) 1989-02-07 1990-02-06 Procedimiento para la preparacion de eteres de 1-bencil-3-hidroximetil-indazol con 2-hidroxiacidos alifaticos y procedimiento para la preparacion de compuesto intermediario utilizado en el mismo
FI900577A FI102678B (sv) 1989-02-07 1990-02-06 Förfarande för framställning av terapeutiskt användbara 1-bensyl-3-hyd roximetyl-indazoletrar och mellanproduktförening
BG091122A BG50273A3 (en) 1989-02-07 1990-02-06 Method for the preparation of esters of the 1- benzyl- 3- hydroxymethylinedazol
CS90563A CZ280121B6 (cs) 1989-02-07 1990-02-06 Éter 1-benzyl-3-hydroxymetylindazolu s alifytickými 2-hydroxykyselinami, způsob jeho přípravy, meziprodukt tohoto postupu a farmaceutický prostředek, obsahující uvedený éter
BG093295A BG50274A3 (en) 1989-02-07 1990-02-06 Method for the preparation of esters of 1- benzyl- 3- hydroxymethyl- indazol
UA4743128A UA26852C2 (uk) 1989-02-07 1990-02-06 Спосіб одержаhhя похідhих 1-беhзил-3-оксиметиліhдазолу або їх солей з фармацевтичhо прийhятhими осhовами
PT93067A PT93067B (pt) 1989-02-07 1990-02-06 Processo para a preparacao de derivados de 2-hidroxiacidos alifaticos e de eteres de 1-benzil-3-hidroximetilindazol, e de composicoes farmaceuticas que os contem
HU90689A HU204793B (en) 1989-02-07 1990-02-06 Process for producing ethers of 1-benzyl-3-hydroxymethyl indazole formed with aliphatic 2-hydroxy acids and pharmaceutical compositions comprising same
BG093291A BG51352A3 (en) 1989-02-07 1990-02-06 Process for preparation of ethers of 1-benzil-3hydroxymethyl-indasol
SU904743128A RU2066318C1 (ru) 1989-02-07 1990-02-06 Производные 1-бензил-3-оксиметилиндазола или их соли с фармацевтически приемлемыми основаниями и промежуточные вещества для их получения
PH40002A PH26552A (en) 1989-02-07 1990-02-06 Ethers of 1-benzyl-3-hydroxy-methyl-indazole with aliphatic 2-hydroxyacids
BG093296A BG50275A3 (en) 1989-02-07 1990-02-06 Method for the preparation of derivatives of 1- benzyl- indazol- 3- il
JP2027007A JP2870925B2 (ja) 1989-02-07 1990-02-06 脂肪族２‐ヒドロキシ酸と１‐ベンジル‐３‐ヒドロキシメチル‐インダゾールのエーテル
EG6290A EG19170A (en) 1989-02-07 1990-02-06 A process for preparing of ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2- hydroxyacids
SK563-90A SK278441B6 (en) 1989-02-07 1990-02-06 Ether of 1-benzyl-3-hydroxymethylindazole with aliphatic 2-hydroxy acids, preparation method and intermediate product thereof, pharmaceutical composition containing same and application
DD90342349A DD295363A5 (de) 1989-02-07 1990-02-07 Verfahren zur herstellung von 1-benzyl-indazol-3-yl-zwischenprodukten
KR1019900001453A KR0145525B1 (ko) 1989-02-07 1990-02-07 지방족 2-히드록시산을 갖는 1-벤질-3-히드록시메틸-인다졸의 에테르
DD90337657A DD291995A5 (de) 1989-02-07 1990-02-07 Verfahren zur herstellung von aethern der verbindung 1-benzyl-3-hydroxy-methyl-indazol mit aliphatischen 2-hydroxysaeuren
CA002009503A CA2009503C (en) 1989-02-07 1990-02-07 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids
CN90100599A CN1046505C (zh) 1989-02-07 1990-02-07 1－苄基－3－羟甲基－吲唑与脂族2－羟基酸的醚的制法
US07/632,117 US5112986A (en) 1989-02-07 1990-12-20 1-benzyl-3-hydroxymethyl-indazole compounds and derivatives
SU914895540A RU2044729C1 (ru) 1989-02-07 1991-06-05 Способ получения простых эфиров 1-бензил-3-гидроксиметилиндазола или их фармацевтически приемлемых солей
SU914895526A RU2055071C1 (ru) 1989-02-07 1991-06-05 Способ получения простых эфиров 1-бензил-3-гидроксиметилиндазола с алифатическими 2-гидроксикислотами
GR91300073T GR910300073T1 (en) 1989-02-07 1991-11-15 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids
LVP-93-647A LV10612B (en) 1989-02-07 1993-06-22 Method for producing of 1-benzyl-3-oxy-methylindazole, it's salts and pharmaceutically acceptable carrier
GEAP19931214A GEP19971030B (en) 1989-02-07 1993-07-26 Method for preparation of derivatives of 1-benzil-3-oximetil-indazolului or salts with pharmaceutically acceptable bases
LTIP872A LT3604B (en) 1989-02-07 1993-08-17 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids
CN93117740A CN1034016C (zh) 1989-02-07 1993-09-15 1-苄基-3-羟甲基-吲唑的制法
HRP-206/90A HRP940878B1 (en) 1989-02-07 1994-10-28 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids
MD95-0055A MD355C2 (ro) 1989-02-07 1994-12-28 Procedeu de preparare a derivaţilor 1-benzil-3-oximetilindazolului sau a sărurilor lui cu baze farmaceutic acceptabile
GR950403284T GR3018165T3 (en) 1989-02-07 1995-11-22 Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8947620A IT1230441B (it) 1989-02-07 1989-02-07 Eteri della serie dell'indazolo

Publications (2)

Publication Number Publication Date
IT8947620A0 IT8947620A0 (it) 1989-02-07
IT1230441B true IT1230441B (it) 1991-10-23

Family

ID=11261479

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8947620A IT1230441B (it) 1989-02-07 1989-02-07 Eteri della serie dell'indazolo

Country Status (36)

Country Link
US (2) US4999367A (sv)
EP (1) EP0382276B1 (sv)
JP (1) JP2870925B2 (sv)
KR (1) KR0145525B1 (sv)
CN (2) CN1046505C (sv)
AR (1) AR247386A1 (sv)
AT (1) ATE127115T1 (sv)
AU (1) AU624895B2 (sv)
BG (1) BG50273A3 (sv)
CA (1) CA2009503C (sv)
CZ (1) CZ280121B6 (sv)
DD (2) DD291995A5 (sv)
DE (2) DE382276T1 (sv)
DK (1) DK0382276T3 (sv)
EG (1) EG19170A (sv)
ES (1) ES2020171T3 (sv)
FI (1) FI102678B (sv)
GE (1) GEP19971030B (sv)
GR (2) GR910300073T1 (sv)
HU (1) HU204793B (sv)
IL (1) IL93132A (sv)
IN (1) IN170957B (sv)
IT (1) IT1230441B (sv)
LT (1) LT3604B (sv)
LV (1) LV10612B (sv)
NZ (1) NZ232258A (sv)
PE (1) PE25091A1 (sv)
PH (1) PH26552A (sv)
PL (2) PL163730B1 (sv)
PT (1) PT93067B (sv)
RO (1) RO106252B1 (sv)
RU (3) RU2066318C1 (sv)
SK (1) SK278441B6 (sv)
UA (1) UA26852C2 (sv)
YU (1) YU47943B (sv)
ZA (1) ZA90644B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1253703B (it) * 1991-04-22 1995-08-23 Angelini Francesco Ist Ricerca Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie
IT1293795B1 (it) 1997-07-28 1999-03-10 Angelini Ricerche Spa Farmaco attivo nel ridurre la produzione di proteina mcp-1
US5943270A (en) * 1997-11-26 1999-08-24 Intel Corporation Two-transistor DRAM cell for logic process technology
US7514463B2 (en) * 2004-08-20 2009-04-07 University Of Kansas Lonidamine analogues and their use in male contraception and cancer treatment
ITMI20062254A1 (it) 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
PL2254869T3 (pl) * 2008-03-07 2017-10-31 Acraf Nowe pochodne 1-benzylo-3-hydroksymetyloindazolu i ich zastosowanie w leczeniu chorób bazujących na ekspresji CX3CR1 i p40
HUE026910T2 (en) 2008-03-07 2016-07-28 Acraf 1-Benzyl-3-hydroxymethylindazole derivatives and their use in the treatment of MCP-1 and CX3CR1 expression-based diseases
PL2262778T3 (pl) 2008-03-07 2020-02-28 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Pochodne 1-benzylo-3-hydroksymetyloindazolu i ich zastosowanie w leczeniu chorób opartych na ekspresji MCP-1, CXCR1 i p40
KR101736301B1 (ko) * 2009-08-03 2017-05-29 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 1-벤질-3-하이드록시메틸-1ｈ-인다졸 및 이의 유도체 및 필요한 마그네슘 중간체들의 제조 방법
UA108742C2 (uk) * 2009-09-23 2015-06-10 Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
AU2013255050B2 (en) 2012-05-01 2016-07-28 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
AU2013261718B2 (en) 2012-05-18 2017-10-19 Sanofi Pyrazole derivatives and their use as LPAR5 antagonists
JP2015521183A (ja) 2012-05-18 2015-07-27 サノフイ ピリジン誘導体および病理学的血栓形成に関連する状態の治療へのその使用
CN108047136B (zh) * 2017-12-20 2021-07-09 长春普华制药股份有限公司 一种苄达酸的精制方法
CA3144861A1 (en) 2019-06-25 2020-12-30 Translatum Medicus, Inc. Processes of making 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives
CN113929627A (zh) * 2021-10-19 2022-01-14 吕梁学院 一种宾达利的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL28032A (en) * 1966-08-29 1971-08-25 Acraf Indazol-3-yl-oxyalkanoic acids and process for the preparation thereof
US3470298A (en) * 1969-01-29 1969-09-30 Acraf Topical anti-inflammatory composition containing (indazole-3-yl)-oxyalkanoic acids
IT1131779B (it) 1980-07-29 1986-06-25 Acraf Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione
IT1189052B (it) 1981-11-27 1988-01-28 Acraf Trattamento della cataratta
IT1194564B (it) 1983-04-18 1988-09-22 Acraf Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa
IT1197805B (it) 1986-08-01 1988-12-06 Acraf Metodo per il tratamento di lenti a contatto

Also Published As

Publication number Publication date
ZA90644B (en) 1991-01-30
PT93067B (pt) 1995-12-29
CN1046505C (zh) 1999-11-17
YU47943B (sh) 1996-07-24
YU20690A (sh) 1992-07-20
HUT53088A (en) 1990-09-28
FI900577A0 (fi) 1990-02-06
CN1034016C (zh) 1997-02-12
CZ56390A3 (en) 1995-06-14
IL93132A0 (en) 1990-11-05
HU204793B (en) 1992-02-28
HU900689D0 (en) 1990-04-28
LV10612A (lv) 1995-04-20
RU2055071C1 (ru) 1996-02-27
EP0382276B1 (en) 1995-08-30
KR900012913A (ko) 1990-09-03
NZ232258A (en) 1991-06-25
PE25091A1 (es) 1991-08-17
PL163730B1 (pl) 1994-04-29
JPH02240065A (ja) 1990-09-25
DD291995A5 (de) 1991-07-18
GR3018165T3 (en) 1996-02-29
JP2870925B2 (ja) 1999-03-17
ES2020171A4 (es) 1991-08-01
EP0382276A3 (en) 1990-12-12
CA2009503C (en) 2000-04-11
DD295363A5 (de) 1991-10-31
PL163720B1 (pl) 1994-04-29
AR247386A1 (es) 1994-12-29
CZ280121B6 (cs) 1995-11-15
UA26852C2 (uk) 1999-12-29
CA2009503A1 (en) 1990-08-07
KR0145525B1 (ko) 1998-08-17
CN1044810A (zh) 1990-08-22
SK56390A3 (en) 1997-05-07
CN1088201A (zh) 1994-06-22
AU624895B2 (en) 1992-06-25
IL93132A (en) 1994-05-30
PT93067A (pt) 1990-08-31
FI102678B1 (sv) 1999-01-29
GEP19971030B (en) 1997-06-13
FI102678B (sv) 1999-01-29
ATE127115T1 (de) 1995-09-15
EP0382276A2 (en) 1990-08-16
US4999367A (en) 1991-03-12
DE382276T1 (de) 1991-11-28
ES2020171T3 (es) 1995-12-01
DK0382276T3 (da) 1996-01-15
US5112986A (en) 1992-05-12
GR910300073T1 (en) 1991-11-15
EG19170A (en) 1994-11-30
BG50273A3 (en) 1992-06-15
LT3604B (en) 1995-12-27
LTIP872A (en) 1995-03-27
IN170957B (sv) 1992-06-20
LV10612B (en) 1995-08-20
SK278441B6 (en) 1997-05-07
RU2044729C1 (ru) 1995-09-27
AU4906690A (en) 1990-08-16
IT8947620A0 (it) 1989-02-07
RO106252B1 (ro) 1993-03-31
DE69021902D1 (de) 1995-10-05
PH26552A (en) 1992-08-19
RU2066318C1 (ru) 1996-09-10
DE69021902T2 (de) 1996-05-23

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