IT1193529B - Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo - Google Patents

Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Info

Publication number
IT1193529B
IT1193529B IT21550/80A IT2155080A IT1193529B IT 1193529 B IT1193529 B IT 1193529B IT 21550/80 A IT21550/80 A IT 21550/80A IT 2155080 A IT2155080 A IT 2155080A IT 1193529 B IT1193529 B IT 1193529B
Authority
IT
Italy
Prior art keywords
adenosinic
inflammatory
derivatives
contain
active principle
Prior art date
Application number
IT21550/80A
Other languages
English (en)
Italian (it)
Other versions
IT8021550A0 (it
Inventor
Giorgio Stramentioli
Original Assignee
Bioresearch Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Srl filed Critical Bioresearch Srl
Publication of IT8021550A0 publication Critical patent/IT8021550A0/it
Priority to IT21550/80A priority Critical patent/IT1193529B/it
Priority to BE0/204529A priority patent/BE888472A/fr
Priority to ES501539A priority patent/ES501539A0/es
Priority to JP5930181A priority patent/JPS56166117A/ja
Priority to AR285020A priority patent/AR231144A1/es
Priority to NO811346A priority patent/NO150515C/no
Priority to SE8102489A priority patent/SE460198B/sv
Priority to LU83307A priority patent/LU83307A1/fr
Priority to CA000375784A priority patent/CA1198105A/en
Priority to DK176481A priority patent/DK159453C/da
Priority to NL8101984A priority patent/NL192111C/nl
Priority to CH4716/84A priority patent/CH650514A5/de
Priority to FR8107992A priority patent/FR2491761A1/fr
Priority to CH263281A priority patent/CH645544A5/de
Priority to MX10149781U priority patent/MX6553E/es
Priority to GB8112428A priority patent/GB2074446B/en
Priority to FI811249A priority patent/FI70227C/fi
Priority to DE19813116067 priority patent/DE3116067A1/de
Priority to ES511039A priority patent/ES8306378A1/es
Priority to GB08321947A priority patent/GB2144409B/en
Priority to FI834113A priority patent/FI68629C/fi
Priority to DK25184A priority patent/DK163518C/da
Priority to NO840343A priority patent/NO157863C/no
Priority to GB08413454A priority patent/GB2144038B/en
Priority to CA000490761A priority patent/CA1209915A/en
Priority to SE8700913A priority patent/SE466238B/sv
Priority to SE8700914A priority patent/SE464635B/sv
Application granted granted Critical
Publication of IT1193529B publication Critical patent/IT1193529B/it
Priority to JP1022771A priority patent/JPH01301692A/ja
Priority to MX9203630A priority patent/MX9203630A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT21550/80A 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo IT1193529B (it)

Priority Applications (29)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo
BE0/204529A BE888472A (fr) 1980-04-22 1981-04-17 Compositions pharmaceutiques a base de derives d'adenosine et leur preparation,
ES501539A ES501539A0 (es) 1980-04-22 1981-04-21 Un procedimiento para la preparacion de derivados de adeno- sina
JP5930181A JPS56166117A (en) 1980-04-22 1981-04-21 Antiinflammatory and analgesic adenosine derivative and therapeutical composition containing it as effective component
AR285020A AR231144A1 (es) 1980-04-22 1981-04-21 Procedimiento para la preparacion de 5'-desoxi-5'-metilticadenosina con actividad antiinflamatoria y analgesica
NO811346A NO150515C (no) 1980-04-22 1981-04-21 Fremgangsmaate ved fremstilling av 5`-deoxy-5`-methylthioadenosin
SE8102489A SE460198B (sv) 1980-04-22 1981-04-21 Foerfarande foer framstaellning av 5'-deoxi-5'-metyltioadenosin
LU83307A LU83307A1 (fr) 1980-04-22 1981-04-21 Derives d'adenosine a activite anti-inflammatoire et analgesique,ainsi que des compositions therapeutiques contenant ces derives comme principe actif
CA000375784A CA1198105A (en) 1980-04-22 1981-04-21 Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle
DK176481A DK159453C (da) 1980-04-22 1981-04-21 Fremgangsmaade til fremstilling af 5'-deoxy-5'-methylthioadenosin
MX10149781U MX6553E (es) 1980-04-22 1981-04-22 Procedimiento para preparar 5'-desoxi-5'-metiltioadenosina
CH4716/84A CH650514A5 (de) 1980-04-22 1981-04-22 Verfahren zur herstellung von 5'-desoxy-5'-methylthioadenosin.
FR8107992A FR2491761A1 (fr) 1980-04-22 1981-04-22 Derives de l'adenosine a activite anti-inflammatoire et analgesique et compositions therapeutiques qui les contiennent en tant que principe actif
CH263281A CH645544A5 (de) 1980-04-22 1981-04-22 Therapeutisches, adenosin-derivate mit entzuendungshemmender, analgetischer und antipyretischer wirksamkeit enthaltendes mittel.
NL8101984A NL192111C (nl) 1980-04-22 1981-04-22 Geneesmiddelpreparaat met anti-inflammatoire werking.
GB8112428A GB2074446B (en) 1980-04-22 1981-04-22 Adenosine derivatives of antiinflammatory and analgesic activity and therapeutic compositions containing them
FI811249A FI70227C (fi) 1980-04-22 1981-04-22 Foerfarande foer framstaellning av terapeutiskt anvaendbara adnosinderivat
DE19813116067 DE3116067A1 (de) 1980-04-22 1981-04-22 Therapeutische zusammensetzungen mit schmerzstillenden und entzuendungshemmenden eigenschaften, die als wirkstoffe adenosinderivate enthalten
ES511039A ES8306378A1 (es) 1980-04-22 1982-04-01 "un procedimiento para la preparacion de derivados de adenosina".
GB08321947A GB2144409B (en) 1980-04-22 1983-08-15 Preparation of 5'-deoxy-5'-methylthioadenosine
FI834113A FI68629C (fi) 1980-04-22 1983-11-09 Foerfarande foer framstaellning av 5'-deoxy-5'-metyltioadenosin
DK25184A DK163518C (da) 1980-04-22 1984-01-20 Analogifremgangsmaade til fremstilling af terapeutisk virksomme adenosinderivater
NO840343A NO157863C (no) 1980-04-22 1984-01-30 Analogifremgangsmaate ved fremstilling av terapeutisk aktive adenosinderivater.
GB08413454A GB2144038B (en) 1980-04-22 1984-05-25 Adenosine derivatives of anti-inflammatory and analgesic activity and therapeutic compositions containing them
CA000490761A CA1209915A (en) 1980-04-22 1985-09-13 Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle
SE8700913A SE466238B (sv) 1980-04-22 1987-03-04 Terapeutisk komposition innehaallande adenosinderivat
SE8700914A SE464635B (sv) 1980-04-22 1987-03-04 Anvaendning av ett adenosinderivat foer framstaellning av ett laekemedel foer behandling av inflammation, smaerta och feber
JP1022771A JPH01301692A (ja) 1980-04-22 1989-02-02 ５’―デオキシ―５’―メチルチオアデノシンの新規な製造方法
MX9203630A MX9203630A (es) 1980-04-22 1992-06-26 Derivados de adenosina y composiciones terapeuticas que los contienen como principio activo de actividad analgesica y antiinflamatoria.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Publications (2)

Publication Number Publication Date
IT8021550A0 IT8021550A0 (it) 1980-04-22
IT1193529B true IT1193529B (it) 1988-07-08

Family

ID=11183457

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Country Status (17)

Country Link
JP (2) JPS56166117A (US07413550-20080819-C00001.png)
AR (1) AR231144A1 (US07413550-20080819-C00001.png)
BE (1) BE888472A (US07413550-20080819-C00001.png)
CA (1) CA1198105A (US07413550-20080819-C00001.png)
CH (2) CH645544A5 (US07413550-20080819-C00001.png)
DE (1) DE3116067A1 (US07413550-20080819-C00001.png)
DK (1) DK159453C (US07413550-20080819-C00001.png)
ES (2) ES501539A0 (US07413550-20080819-C00001.png)
FI (1) FI70227C (US07413550-20080819-C00001.png)
FR (1) FR2491761A1 (US07413550-20080819-C00001.png)
GB (3) GB2074446B (US07413550-20080819-C00001.png)
IT (1) IT1193529B (US07413550-20080819-C00001.png)
LU (1) LU83307A1 (US07413550-20080819-C00001.png)
MX (1) MX9203630A (US07413550-20080819-C00001.png)
NL (1) NL192111C (US07413550-20080819-C00001.png)
NO (1) NO150515C (US07413550-20080819-C00001.png)
SE (3) SE460198B (US07413550-20080819-C00001.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (it) * 1984-12-06 1987-08-26 Bioresearch Spa Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica
IT1227049B (it) * 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
JPH0497287A (ja) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd 画像表示集積回路
ES2259552B1 (es) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
RS51122B (sr) * 2005-03-17 2010-10-31 Proyecto De Biomedicina Cima S.L. Primena 5`-metiltioadenozina(mta) kod prevencije i/ili lečenja autoimunih bolesti i/ili pri odbacivanju transplantata
DE102010027595A1 (de) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Vermeidung von Ischämie- oder Degenerations-Schäden im Gehirn bei Anwendung von Adenosin-Derivaten
DE102011005232A1 (de) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosin und seine Derivate zur Verwendung in der Schmerztherapie
WO2014163152A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 ノンレム睡眠促進剤、深睡眠促進剤および自然睡眠誘発剤
WO2014163151A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 酵母培養物及び内服組成物
KR102245628B1 (ko) * 2013-04-05 2021-04-28 라이온 가부시키가이샤 내복 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (de) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 5'-Sulfoxyde von Nucleosiden
DE1545645A1 (de) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Verfahren zur Herstellung von disubstituierten Adenosin-Derivaten
FR2252405B1 (US07413550-20080819-C00001.png) * 1973-11-27 1978-04-28 Ajinomoto Kk
FR2313937A1 (fr) * 1975-06-09 1977-01-07 Anvar Medicament a base de 5' thioethers de l'adenosine
FR2424027A1 (fr) * 1978-04-28 1979-11-23 Merieux Inst Nouveau medicament, notamment sedatif et inducteur de sommeil et compositions pharmaceutiques la renfermant

Also Published As

Publication number Publication date
GB2144409B (en) 1985-09-11
JPH0246599B2 (US07413550-20080819-C00001.png) 1990-10-16
FR2491761B1 (US07413550-20080819-C00001.png) 1984-01-06
GB8321947D0 (en) 1983-09-14
SE466238B (sv) 1992-01-20
CH650514A5 (de) 1985-07-31
ES8206551A1 (es) 1982-08-16
JPS56166117A (en) 1981-12-21
NO811346L (no) 1981-10-23
NO150515B (no) 1984-07-23
SE8700914D0 (sv) 1987-03-04
CA1198105A (en) 1985-12-17
NL192111B (nl) 1996-10-01
GB2144038A (en) 1985-02-27
SE8700913L (sv) 1987-03-04
DE3116067C2 (US07413550-20080819-C00001.png) 1992-12-17
DK159453C (da) 1991-03-18
JPH01301692A (ja) 1989-12-05
SE8700914L (sv) 1987-03-04
GB2074446A (en) 1981-11-04
FI70227C (fi) 1986-09-15
NL8101984A (nl) 1981-11-16
IT8021550A0 (it) 1980-04-22
SE8102489L (sv) 1981-10-23
SE464635B (sv) 1991-05-27
GB8413454D0 (en) 1984-07-04
FR2491761A1 (fr) 1982-04-16
SE8700913D0 (sv) 1987-03-04
SE460198B (sv) 1989-09-18
ES501539A0 (es) 1982-08-16
DE3116067A1 (de) 1982-03-11
BE888472A (fr) 1981-08-17
GB2074446B (en) 1985-04-11
AR231144A1 (es) 1984-09-28
ES511039A0 (es) 1983-06-01
DK159453B (da) 1990-10-15
CH645544A5 (de) 1984-10-15
ES8306378A1 (es) 1983-06-01
LU83307A1 (fr) 1981-07-24
GB2144409A (en) 1985-03-06
NL192111C (nl) 1997-02-04
DK176481A (da) 1981-10-23
JPH0249288B2 (US07413550-20080819-C00001.png) 1990-10-29
MX9203630A (es) 1992-09-01
FI70227B (fi) 1986-02-28
NO150515C (no) 1984-10-31
GB2144038B (en) 1985-08-29
FI811249L (fi) 1981-10-23

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960429