IT1168389B - Derivati di alcandioli con attivita' ipolipidemizzante,metodi per la loro preparazione e composizioni farmaceutiche che li contengono - Google Patents

Derivati di alcandioli con attivita' ipolipidemizzante,metodi per la loro preparazione e composizioni farmaceutiche che li contengono

Info

Publication number
IT1168389B
IT1168389B IT03423/81A IT342381A IT1168389B IT 1168389 B IT1168389 B IT 1168389B IT 03423/81 A IT03423/81 A IT 03423/81A IT 342381 A IT342381 A IT 342381A IT 1168389 B IT1168389 B IT 1168389B
Authority
IT
Italy
Prior art keywords
hypolipidemizing
alcandiol
derivatives
activity
contain
Prior art date
Application number
IT03423/81A
Other languages
English (en)
Other versions
IT8103423A0 (it
Inventor
Manlio Cristofori
Valerio Borzatta
Mauro Morotti
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Priority to IT03423/81A priority Critical patent/IT1168389B/it
Publication of IT8103423A0 publication Critical patent/IT8103423A0/it
Priority to US06/369,579 priority patent/US4454145A/en
Priority to EP82103725A priority patent/EP0064286A3/en
Priority to JP57075060A priority patent/JPS57192364A/ja
Application granted granted Critical
Publication of IT1168389B publication Critical patent/IT1168389B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18Polyhydroxylic acyclic alcohols
    • C07C31/20Dihydroxylic alcohols
IT03423/81A 1981-05-06 1981-05-06 Derivati di alcandioli con attivita' ipolipidemizzante,metodi per la loro preparazione e composizioni farmaceutiche che li contengono IT1168389B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT03423/81A IT1168389B (it) 1981-05-06 1981-05-06 Derivati di alcandioli con attivita' ipolipidemizzante,metodi per la loro preparazione e composizioni farmaceutiche che li contengono
US06/369,579 US4454145A (en) 1981-05-06 1982-04-19 Nicotinates of alkanediols having hypolipidaemic activity and pharmaceutical compositions containing them
EP82103725A EP0064286A3 (en) 1981-05-06 1982-04-30 New derivatives of alkanediols having hypolipidaemic activity, methods for their preparation and pharmaceutical compositions containing them
JP57075060A JPS57192364A (en) 1981-05-06 1982-05-04 Alkanediol derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03423/81A IT1168389B (it) 1981-05-06 1981-05-06 Derivati di alcandioli con attivita' ipolipidemizzante,metodi per la loro preparazione e composizioni farmaceutiche che li contengono

Publications (2)

Publication Number Publication Date
IT8103423A0 IT8103423A0 (it) 1981-05-06
IT1168389B true IT1168389B (it) 1987-05-20

Family

ID=11107069

Family Applications (1)

Application Number Title Priority Date Filing Date
IT03423/81A IT1168389B (it) 1981-05-06 1981-05-06 Derivati di alcandioli con attivita' ipolipidemizzante,metodi per la loro preparazione e composizioni farmaceutiche che li contengono

Country Status (4)

Country Link
US (1) US4454145A (it)
EP (1) EP0064286A3 (it)
JP (1) JPS57192364A (it)
IT (1) IT1168389B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199652B (it) * 1985-01-28 1988-12-30 Boehringer Biochemia Srl Composti ad attivita'antiiperlipidemica,loro preparazione e composizioni farmaceutiche che li contengono
US5648387A (en) * 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
CA2735688A1 (en) * 2008-09-22 2010-03-25 The Procter & Gamble Company Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon
US8232431B2 (en) * 2008-09-22 2012-07-31 The Procter & Gamble Company Specific branched surfactants and consumer products
JP7164081B2 (ja) * 2019-01-18 2022-11-01 三井化学株式会社 エステル化合物及びその製造方法、熱可塑性樹脂用可塑剤、並びに、熱可塑性樹脂組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB910762A (en) * 1960-03-09 1962-11-21 Tmm Research Ltd Improvements relating to apparatus for packaging textile slivers in coiled formation
GB910262A (en) * 1960-06-11 1962-11-14 Bofors Ab New nicotinic acid esters and methods of producing them
FR3678M (fr) * 1964-01-16 1965-11-15 Rech S Pharma Erphar Soc Et Le nicotinate de 2-méthyl, 2-propylpropane diol-1,3 comme nouveau médicament des douleurs musculaires, des affections artérielles et veineuses et les compositions pharmaceutiques pour son utilisation.
GB1213162A (en) * 1966-11-16 1970-11-18 Astra Ab Serum lipid lowering pyridine derivatives and their preparation
FR2035754A1 (it) * 1969-02-21 1970-12-24 Roussel Uclaf
US3930024A (en) * 1969-09-02 1975-12-30 Parke Davis & Co Pharmaceutical compositions and methods
US3857884A (en) * 1970-04-17 1974-12-31 Parke Davis & Co Tetramethylalkane derivatives
US3742068A (en) * 1970-04-17 1973-06-26 G Moersch Ethers of 2,2,9,9-tetramethyl-1,10-decanediol
ES469531A1 (es) * 1978-05-05 1978-12-01 Alter Lab Un procedimiento de preparacion de ciertos diesteres de eti-lenglicol.
JPS5959844U (ja) * 1982-10-15 1984-04-19 株式会社クボタ 脱穀選別装置

Also Published As

Publication number Publication date
EP0064286A2 (en) 1982-11-10
JPS57192364A (en) 1982-11-26
EP0064286A3 (en) 1983-03-02
IT8103423A0 (it) 1981-05-06
US4454145A (en) 1984-06-12

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