IT1188916B - Composti chinolonici composizioni terapeutiche che li contengono e procedimento per prepararli - Google Patents

Composti chinolonici composizioni terapeutiche che li contengono e procedimento per prepararli

Info

Publication number
IT1188916B
IT1188916B IT48262/80A IT4826280A IT1188916B IT 1188916 B IT1188916 B IT 1188916B IT 48262/80 A IT48262/80 A IT 48262/80A IT 4826280 A IT4826280 A IT 4826280A IT 1188916 B IT1188916 B IT 1188916B
Authority
IT
Italy
Prior art keywords
quinolonic
prepare
procedure
compositions containing
therapeutic compositions
Prior art date
Application number
IT48262/80A
Other languages
English (en)
Other versions
IT8048262A0 (it
IT8048262A1 (it
Inventor
Roy Victor Davies
Original Assignee
Boots Co Ltd
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Ltd, Boots Co Plc filed Critical Boots Co Ltd
Publication of IT8048262A0 publication Critical patent/IT8048262A0/it
Publication of IT8048262A1 publication Critical patent/IT8048262A1/it
Application granted granted Critical
Publication of IT1188916B publication Critical patent/IT1188916B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT48262/80A 1979-03-27 1980-03-26 Composti chinolonici composizioni terapeutiche che li contengono e procedimento per prepararli IT1188916B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7910558 1979-03-27
GB7939505 1979-11-15

Publications (3)

Publication Number Publication Date
IT8048262A0 IT8048262A0 (it) 1980-03-26
IT8048262A1 IT8048262A1 (it) 1981-09-26
IT1188916B true IT1188916B (it) 1988-01-28

Family

ID=26271029

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48262/80A IT1188916B (it) 1979-03-27 1980-03-26 Composti chinolonici composizioni terapeutiche che li contengono e procedimento per prepararli

Country Status (34)

Country Link
US (1) US4302460A (it)
KR (1) KR840001612B1 (it)
AT (1) AT379390B (it)
AU (1) AU536616B2 (it)
BG (2) BG37993A3 (it)
CA (1) CA1151652A (it)
CH (1) CH644366A5 (it)
CS (1) CS221906B2 (it)
DD (1) DD149608A5 (it)
DE (2) DE3051205C2 (it)
DK (1) DK151252C (it)
EG (1) EG16606A (it)
FI (1) FI77026C (it)
FR (2) FR2452484A1 (it)
GR (1) GR68007B (it)
HK (1) HK94986A (it)
HU (1) HU179845B (it)
IE (1) IE49562B1 (it)
IL (1) IL59710A (it)
IT (1) IT1188916B (it)
KE (1) KE3649D (it)
LU (1) LU82295A1 (it)
MX (1) MX6816E (it)
MY (1) MY8600668A (it)
NL (1) NL191306C (it)
NO (1) NO156787C (it)
NZ (1) NZ193167A (it)
PH (1) PH16758A (it)
PL (1) PL124037B1 (it)
PT (1) PT71006A (it)
RO (1) RO79397A (it)
SE (1) SE455422B (it)
SG (1) SG60886G (it)
YU (1) YU42332B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
US4552884A (en) * 1984-01-13 1985-11-12 The Boots Company Plc Method of treating heart disease
EP0172004B1 (en) * 1984-08-15 1990-03-21 The Boots Company PLC Quinolinones, process for their preparation and pharmaceutical compositions containing them
GB8515207D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8627698D0 (en) * 1986-11-20 1986-12-17 Boots Co Plc Therapeutic agents
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
GB8804016D0 (en) * 1988-02-22 1988-03-23 Boots Co Plc Therapeutic agents
GB8918952D0 (en) * 1989-08-19 1989-10-04 Boots Co Plc Therapeutic agents
FR2680511B1 (fr) * 1991-08-20 1995-05-19 Roussel Uclaf Derives n-substitues de la quinoleine, leur procede de preparation, intermediaires obtenus, leur application comme medicaments et les compositions les renfermant.
IL100555A (en) * 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
FR2684671B1 (fr) * 1991-11-20 1995-05-19 Roussel Uclaf Nouveaux derives de la quinoleine, leur procede de preparation et intermediaires et leur application a titre de medicaments.
FR2672597B1 (fr) * 1991-02-07 1995-05-19 Roussel Uclaf Nouveaux derives n-substitues de la quinoleine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
WO2000007595A1 (en) * 1998-08-03 2000-02-17 Basf Corporation Pyridinones for the treatment of sexual dysfunction
US6307050B1 (en) * 2000-08-29 2001-10-23 R. T. Alamo Venture I Llc Method of synthesizing flosequinan from 4-fluoroanthranilic acid
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6458804B1 (en) 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6649764B2 (en) * 2001-10-25 2003-11-18 R. T. Alamo Ventures I, Llc Stereospecific enrichment of heterocyclic enantiomers
US6730790B2 (en) * 2002-03-01 2004-05-04 R.T. Alamo Ventures I. Llc Chlorinated heterocyclic compounds and methods of synthesis

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3178348A (en) * 1961-02-08 1965-04-13 Norwich Pharma Co Hypotensive quinolines
GB1066919A (en) 1964-04-03 1967-04-26 Hoffmann La Roche Novel benzyl amine derivatives
DE1770482A1 (de) * 1968-05-22 1971-11-11 Basf Ag Verfahren zur Herstellung von 2,4-Dioxychinolinen
US3798219A (en) * 1971-10-18 1974-03-19 Warner Lambert Co 3-(methylsulfinyl)cinnolinones and their derivatives
US3772301A (en) * 1971-11-22 1973-11-13 Warner Lambert Co (4-substituted)4-(methylsulfinyl)methylcarbostyrils
CH607848A5 (it) * 1974-06-04 1978-11-30 Bayer Ag
GB1488411A (en) * 1975-01-16 1977-10-12 Wyeth John & Brother Ltd 3,4-dihydro-4-arylquinolin-4-ol derivatives
US4127574A (en) * 1976-03-01 1978-11-28 Sandoz, Inc. 4-Hydroxy-3-sulfonyl-quinolin-2(1H)-ones
US4124587A (en) * 1976-03-01 1978-11-07 Sandoz, Inc. 4-Hydroxy-3-sulfinyl-quinolin-2(1H)-ones
DE2616991A1 (de) 1976-04-17 1977-10-27 Bayer Ag Heterocyclisch-substituierte schwefelhaltige dihydropyridine, mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2616995A1 (de) 1976-04-17 1977-10-27 Bayer Ag 1.4-dihydropyridine mit schwefelhaltigen substituenten mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2639257A1 (de) 1976-09-01 1978-03-02 Bayer Ag Aminoalkylidenamino-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2639498A1 (de) 1976-09-02 1978-03-09 Bayer Ag Neue schwefelhaltige amino-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2641746C2 (de) 1976-09-16 1986-11-06 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-Zuckerderivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2658183A1 (de) 1976-12-22 1978-07-06 Bayer Ag In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2658804A1 (de) 1976-12-24 1978-07-06 Bayer Ag Kreislaufbeeinflussende mittel
US4177278A (en) * 1977-04-05 1979-12-04 Bayer Aktiengesellschaft 2-Alkyleneaminodihydropyridines compounds, their production and their medicinal use
DE2715182A1 (de) 1977-04-05 1978-10-19 Bayer Ag 2-alkylenaminodihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS5424882A (en) * 1977-07-22 1979-02-24 Yamanouchi Pharmaceut Co Ltd Novel heterocyclic compounds and their preparation
DE2747513A1 (de) 1977-10-22 1979-05-03 Bayer Ag Dihydropyridine mit schwefelhaltigen estergruppierungen

Also Published As

Publication number Publication date
FR2468367B1 (it) 1983-09-30
DD149608A5 (de) 1981-07-22
KE3649D (en) 1986-08-01
ATA161880A (de) 1985-05-15
NL191306B (nl) 1994-12-16
PH16758A (en) 1984-02-15
AU536616B2 (en) 1984-05-17
YU42332B (en) 1988-08-31
NL8001771A (nl) 1980-09-30
IE49562B1 (en) 1985-10-30
GR68007B (it) 1981-10-26
LU82295A1 (fr) 1981-04-17
SE8002345L (sv) 1980-11-14
CH644366A5 (fr) 1984-07-31
NO156787B (no) 1987-08-17
YU84980A (en) 1983-09-30
US4302460A (en) 1981-11-24
BG37836A3 (en) 1985-08-15
RO79397A (ro) 1982-06-25
NO800881L (no) 1980-09-29
NO156787C (no) 1987-11-25
IE800567L (en) 1980-09-27
NZ193167A (en) 1984-08-24
IT8048262A0 (it) 1980-03-26
FI77026B (fi) 1988-09-30
HK94986A (en) 1986-12-12
AT379390B (de) 1985-12-27
AU5670280A (en) 1980-10-02
MX6816E (es) 1986-08-05
HU179845B (en) 1982-12-28
PL124037B1 (en) 1982-12-31
KR840001612B1 (ko) 1984-10-11
DK130180A (da) 1980-09-28
DK151252C (da) 1988-05-16
IT8048262A1 (it) 1981-09-26
DE3051205C2 (de) 1991-01-24
FR2452484A1 (fr) 1980-10-24
PL223050A1 (it) 1981-01-30
CS221906B2 (en) 1983-04-29
NL191306C (nl) 1995-05-16
CA1151652A (en) 1983-08-09
IL59710A (en) 1984-01-31
MY8600668A (en) 1986-12-31
SG60886G (en) 1987-03-27
SE455422B (sv) 1988-07-11
FI77026C (fi) 1989-01-10
DE3011994C2 (it) 1991-06-27
KR830001898A (ko) 1983-05-19
EG16606A (en) 1989-01-30
DK151252B (da) 1987-11-16
PT71006A (en) 1980-04-01
FI800923A (fi) 1980-09-28
FR2468367A1 (fr) 1981-05-08
FR2452484B1 (it) 1983-08-12
BG37993A3 (en) 1985-09-16
DE3011994A1 (de) 1980-10-16

Similar Documents

Publication Publication Date Title
IT1188916B (it) Composti chinolonici composizioni terapeutiche che li contengono e procedimento per prepararli
IT1170387B (it) Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
IT1171646B (it) Composti benzoeterociclici e procedimento per prepararli
DE2860546D1 (en) Nitroimidazoles and pharmaceutical compositions containing them as well as their preparation
IT1104842B (it) Composti di cefalosporina composizioni antibiotiche che li contengono e procedimento per prepararli
IT1171335B (it) Derivato di piperazina procedimento per prepararlo e composizione analgesica che lo contiene
IT1079395B (it) Alchilammidi n-alchinil-(fenossi-sostituite)composizioni che le contengono e procedimento per produrle
PH14660A (en) Analgesic compounds and compositions containing same
IT1188985B (it) Fenossiammine eterocicliche sostituite procedimento per prepararle e composizioni farmaceutiche che le contengono
IT1105426B (it) Ciclopropilmetossianilidi composizioni erbicide che le contengono e procedimento per produrle ed applicarle
IT1109281B (it) N-benzil-antracicline procedimento per prepararle e composizioni farmaceutiche che le contengono
IT1133022B (it) Composti perfluoroalchilici e procedimento per prepararli
IT7851723A0 (it) Per prepararli composti antibatterici composizioni che li contengono e procedimento
IT1106924B (it) Derivato di tiazolidina procedimento per prepararlo e composizione farmaceutica che lo contiene
IT7950714A0 (it) Ariltrifluoroetanoli procedimento per prepararli e composizioni farmaceutiche che li contengono
IT1109207B (it) Composti b-lattamici composizioni antibiotiche che li contengono e procedimento per prepararli
IT1145356B (it) Antibiotici cefalosporinici procedimento per prepararli e composizioni che li contengono
IT1189449B (it) Composti chinolonici antiipertensivi composizioni farmaceutiche che li contengono e procedimento per produrli
IT1143081B (it) Antibiotici cefalosporinici composizioni che li contengono e procedimento per produrli ed applicarli
NZ186722A (en) Therapeutic compositions containing transbroparestrol
IT1121507B (it) Composti organo-metallici complessi e composizioni che li contengono
IT1101867B (it) Poliidrossicomposti contenenti gruppi acilureici e procedimento per produrli
IT1207006B (it) Antibiotici cefalosporinici composizioni che li contengono e procedimento per produrli
IT1171389B (it) Composti amminosteroidi composizioni farmaceutiche che li contengono e procentimento per prepararli
IT1111383B (it) Composizione farmaceutica antidiarroica e procedimento per prepararla

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970329