IS7670A - Samsett meðferð fyrir offjölgunar sjúkdóma - Google Patents

Samsett meðferð fyrir offjölgunar sjúkdóma

Info

Publication number
IS7670A
IS7670A IS7670A IS7670A IS7670A IS 7670 A IS7670 A IS 7670A IS 7670 A IS7670 A IS 7670A IS 7670 A IS7670 A IS 7670A IS 7670 A IS7670 A IS 7670A
Authority
IS
Iceland
Prior art keywords
combination therapy
proliferative disease
proliferative
disease
therapy
Prior art date
Application number
IS7670A
Other languages
English (en)
Inventor
Saccuzzo Beebe Jean
Jean Ferrante Karen
Pranlal Jani Jitesh
Lee Schaeffer Tracy
Ingeborg Healey Diane
John O'leary James
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of IS7670A publication Critical patent/IS7670A/is

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IS7670A 2002-08-19 2005-01-27 Samsett meðferð fyrir offjölgunar sjúkdóma IS7670A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40446102P 2002-08-19 2002-08-19
PCT/IB2003/003550 WO2004017964A1 (en) 2002-08-19 2003-08-07 Combination therapy for hyperproliferative diseases

Publications (1)

Publication Number Publication Date
IS7670A true IS7670A (is) 2005-01-27

Family

ID=31946725

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7670A IS7670A (is) 2002-08-19 2005-01-27 Samsett meðferð fyrir offjölgunar sjúkdóma

Country Status (33)

Country Link
US (1) US20070197517A1 (is)
EP (1) EP1545519B1 (is)
JP (1) JP3835763B2 (is)
KR (1) KR100668539B1 (is)
CN (1) CN1681495B (is)
AP (1) AP2005003232A0 (is)
AR (1) AR040995A1 (is)
AT (1) ATE502635T1 (is)
AU (1) AU2003250483A1 (is)
BR (1) BR0313593A (is)
CA (1) CA2495962A1 (is)
CR (1) CR7693A (is)
DE (1) DE60336485D1 (is)
EA (1) EA200500234A1 (is)
EC (1) ECSP055618A (is)
ES (1) ES2362998T3 (is)
GE (1) GEP20074134B (is)
GT (1) GT200300177A (is)
HK (1) HK1079106A1 (is)
HR (1) HRP20050163A2 (is)
IL (1) IL166545A0 (is)
IS (1) IS7670A (is)
MA (1) MA27385A1 (is)
MX (1) MXPA05001958A (is)
NO (1) NO20050621L (is)
OA (1) OA12905A (is)
PA (1) PA8580201A1 (is)
PE (1) PE20040993A1 (is)
PL (1) PL375713A1 (is)
RS (1) RS20050106A (is)
TN (1) TNSN05051A1 (is)
TW (1) TW200403057A (is)
WO (1) WO2004017964A1 (is)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
WO2003101308A1 (en) 2002-06-04 2003-12-11 Office Of Technology Licensing Stanford University Device and method for rapid aspiration and collection of body tissue from within an enclosed body space
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
WO2005102327A1 (en) * 2004-04-20 2005-11-03 Pfizer Products Inc. Dosage forms and methods of treatment using vegfr inhibitors
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US8735394B2 (en) 2005-02-18 2014-05-27 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
KR101914254B1 (ko) 2005-02-18 2018-11-02 아브락시스 바이오사이언스, 엘엘씨 치료제의 조합 및 투여 방식, 및 조합 요법
CN101243093A (zh) * 2005-06-13 2008-08-13 阿斯利康(瑞典)有限公司 用于治疗心律不齐的新型氧杂双哌啶化合物
US8080534B2 (en) * 2005-10-14 2011-12-20 Phigenix, Inc Targeting PAX2 for the treatment of breast cancer
WO2009117769A1 (en) * 2008-03-25 2009-10-01 Newcastle Innovation Limited Inhibition of c-kit cancers
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
NZ717490A (en) 2010-03-29 2017-12-22 Abraxis Bioscience Llc Methods of treating cancer
MX2012011155A (es) 2010-03-29 2012-12-05 Abraxis Bioscience Llc Metodos para mejorar suministros de farmacos y efectividad de agentes terapeuticos.
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
KR20190130050A (ko) 2010-06-04 2019-11-20 아브락시스 바이오사이언스, 엘엘씨 췌장암의 치료 방법
ES2719091T3 (es) * 2010-11-12 2019-07-08 Pharma Mar Sa Terapia de combinación con un inhibidor mitótico
MX2015014701A (es) * 2013-04-24 2016-08-08 Salk Inst For Biological Studi Circuito genomico del receptor de vitamina d/smad que regula la compuerta de la respuesta fibrotica.
EP3003486A4 (en) 2013-06-05 2017-03-08 Salk Institute for Biological Studies Vitamin d receptor agonists to treat diseases involving cxcl12 activity
CN116602954A (zh) * 2015-04-22 2023-08-18 新纳特产品公司 共晶组合物及其药物用途
US10751318B2 (en) 2015-05-18 2020-08-25 Syn-Nat Products Enterprise LLC Pharmaceutical co-crystal and use thereof
WO2016205782A1 (en) 2015-06-19 2016-12-22 Syn-Nat Products Enterprise LLC Composition containing carboplatin and use
KR20180018800A (ko) 2015-06-19 2018-02-21 신-낫 프로덕츠 엔터프라이즈 엘엘씨 카보플라틴 계 공-결정의 약제학적 조성물 및 이의 용도
EP3297640A4 (en) 2015-06-25 2019-01-02 Syn-Nat Products Enterprise LLC Pharmaceutical co-crystal composition and use thereof
JP6741782B2 (ja) 2016-02-01 2020-08-19 レジェンメド システムズ,インコーポレイテッド 組織断裂用カニューレ
WO2019023149A1 (en) 2017-07-24 2019-01-31 Salk Institute For Biological Studies USE OF BROMODOMAIN-CONTAINING PROTEIN-9 ANTAGONISTS IN ASSOCIATION WITH VITAMIN D RECEPTOR AGONISTS IN THE TREATMENT OF DIABETES
US20230098628A1 (en) * 2021-08-23 2023-03-30 Ckp Therapeutics, Inc. Composition for preventing, alleviating or treating cancer
US11738021B2 (en) 2021-08-23 2023-08-29 Ckp Therapeutics, Inc. Composition and method for preventing, alleviating or treating cancer

Family Cites Families (219)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2802005A (en) 1957-08-06 S-eluorourace
US437201A (en) 1890-09-30 Mechanism for testing reed-organs
US2809194A (en) 1957-10-08 Thiadiazine type natriuretic agents
US3262852A (en) 1966-07-26 Vasodilator and anti-anginose com- pounds containing methoxy benzyl piperazines and method of using the same
US3009911A (en) 1961-11-21 Derivatives of j
DE55956C (de) CH. GROOMBRIDGE und W. A. SOUTH in London, 40 New Bond Street Bremskurbel für Pferdebahn- und andere Wagen
US338899A (en) 1886-03-30 Sun-shield for horses
US3108097A (en) 1963-10-22 Ehnojs
US3254076A (en) 1966-05-31 Sulfamyl hydro
US2937169A (en) 1960-05-17 Toiutf alrtqn of h
US2661372A (en) 1953-12-01 Pharmacologically valuable stereo
US2882271A (en) 1959-04-14 Xcixcxh
US2783241A (en) 1957-02-26 S-acylimino-x-substituted-az-i
US3164588A (en) 1965-01-05 Hjnsoj
SE168308C1 (is)
US2976289A (en) 1961-03-21 X-tetrahydro -
US2161938A (en) 1934-07-31 1939-06-13 Soc Of Chemical Ind Imidazolines
DE905738C (de) 1943-06-11 1954-11-02 Diwag Chemische Fabriken Ag Verfahren zur Herstellung basischer Thymoldimethylaminoaethylaether
US2500444A (en) 1944-10-10 1950-03-14 Polaroid Corp Uramidohomomeroquinene
AT168063B (de) 1948-11-23 1951-04-10 Richter Gedeon Vegyeszet Verfahren zur Herstellung von neuen asymmetrischen Substitutionsprodukten des 2,4-Diamino-1,3,5-Triazins
US2554816A (en) 1950-04-04 1951-05-29 American Cyanamid Co Heterocyclic sulfonamides and methods of preparation thereof
DE860217C (de) 1950-10-28 1952-12-18 Albert Ag Chem Werke Verfahren zur Herstellung von 1-Hexyl-3, 7-dimethylxanthin
GB740932A (en) 1952-08-01 1955-11-23 Rhone Poulenc Sa Improvements in or relating to phenthiazine derivatives
US2661373A (en) 1953-03-02 1953-12-01 Kulz Ida Certain amino alcohols and ketones
US2816118A (en) 1953-11-12 1957-12-10 S B Penick & Company Inc Isolation of crystalline components from visnagan
US2909194A (en) 1954-02-15 1959-10-20 Goodyear Tire & Rubber Relay valve
FR1103113A (fr) 1954-04-15 1955-10-31 Triméthylol-alcanes et leur procédé de préparation
GB769757A (en) 1954-05-13 1957-03-13 American Cyanamid Co Improvements in or relating to the manufacture of sulfonamides
US2769015A (en) 1954-10-06 1956-10-30 Lab Laroche Navarron Process of preparing 3-methyl-chromone
GB795174A (en) 1954-10-13 1958-05-21 Upjohn Co Heterocyclic sulphonamides
GB807826A (en) 1955-03-14 1959-01-21 Thomae Gmbh Dr K Derivatives of pyrimido[5,4-d] pyrimidine and production thereof
FR1165845A (fr) 1955-05-28 1958-10-29 Philips Nv Amines secondaires portant des substituants et leur préparation
GB803372A (en) 1955-11-02 1958-10-22 Recordati Lab Farmacologico S Hydroxychromone derivatives and methods of preparing the same
US3012042A (en) 1956-12-21 1961-12-05 Belge Produits Chimiques Sa Benzofurans
BE564542A (is) 1957-02-05
GB824547A (en) 1957-05-07 1959-12-02 Recordati Lab Farmacologico S Process for preparing flavone-7-ethyl oxyacetate
US3055904A (en) 1957-11-04 1962-09-25 Geigy Chem Corp New isoindoline derivatives
US2965655A (en) 1957-11-07 1960-12-20 Merck & Co Inc Process for preparing substituted 1-amino 2, 4-benzene-disulfonamides
US2965656A (en) 1957-11-07 1960-12-20 Merck & Co Inc Process for preparing substituted 1-amino-2, 4-benzene-disulfonamides
US2980699A (en) 1957-12-20 1961-04-18 S B Penick And Company Dihydropyranocoumarin derivatives and process for their production
US3440244A (en) 1958-02-17 1969-04-22 Pfizer & Co C 3,6-disubstituted-7-sulfamyl-1,2,4-benzthiazide-1,1-dioxides
FR1217929A (fr) 1958-03-03 1960-05-06 Ciba Geigy Procédé de préparation du 1,1-dioxyde de la 6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine et de ses sels
CH366523A (de) 1958-04-14 1963-01-15 Eprova Ag Verfahren zur Herstellung der neuen 1,3,4,6- und 1,3,4,5-Tetranicotinoyl-fructose
SU115905A1 (ru) 1958-04-19 1958-11-30 Н.Е. Акопян Препарат ганглерон
NL238796A (is) 1958-05-07
GB851287A (en) 1958-07-10 1960-10-12 British Drug Houses Ltd 5-chlorotoluene-2:4-disulphonamide and alkali metal salts thereof
DE1102750B (de) 1958-07-17 1961-03-23 Wuelfing J A Fa Verfahren zur Herstellung eines Salzes von Theophyllinbasen
GB856409A (en) 1958-07-26 1960-12-14 Chime Et Atomistique Improvements in and relating to a new pyridazine derivative and its process of preparation
GB862248A (en) 1958-08-04 1961-03-08 Italseber S P A Di-isopropylammonium salts of chloroacetic and chloropropionic acids
GB863474A (en) 1958-08-13 1961-03-22 Knud Abildgaard Benzothiadiazine derivatives and their preparation
US2970082A (en) 1958-10-07 1961-01-31 Walker Lab Inc Aluminum nicotinate compositions for hypercholesteremia
GB885078A (en) 1959-01-12 1961-12-20 Ciba Ltd 3:4-dihydro-1:2:4-benzothiadiazine-1:1-dioxides and process for their manufacture
ES255386A1 (es) 1959-02-04 1960-09-16 Ciba Geigy Procedimiento para preparar derivados del 3,4-dihidro-1,2,4-benzotiadiazina-1,1,-diëxido
US3058882A (en) 1959-12-28 1962-10-16 Hoechst Ag N'-substituted-3-carboxy-6-halo-sulfanilamide and derivatives thereof
DE1102973B (de) 1960-03-25 1961-03-23 Bayer Ag Verfahren zur Herstellung von hoch gereinigten Kallikrein-Praeparaten
NL291944A (is) 1960-05-04
DE1265758B (de) 1960-05-25 1968-04-11 Guidotti & C Spa Labor Verfahren zur Herstellung von o-(beta-Dialkylaminoaethoxy)-phenylketonen und deren Saeureadditionssalzen und quartaeren Salzen
US3081230A (en) 1960-09-08 1963-03-12 Smith Kline French Lab Diuretic and antihypertensive triaminoarylpteridines
DE1302648B (is) 1960-09-27
DE1170417B (de) 1960-11-08 1964-05-21 Recip Ab Verfahren zur Herstellung eines Diphenyl-butylamins mit die Coronargefaesse erweiternder Wirkung
NL270803A (is) 1960-11-09
US3255241A (en) 1961-01-19 1966-06-07 Merck & Co Inc (2-alkylidene acyl)phenoxy-and (2-alkylidene acyl)phenylmercaptocarboxylic acids
US3072653A (en) 1961-03-06 1963-01-08 Warner Lamber Pharmaceutical C 5-amino derivatives of 4-thiazolidinones and process therefor
DE1154810B (de) 1961-04-01 1963-09-26 Knoll Ag Verfahren zur Herstellung basisch substituierter Phenylacetonitrile
FR1312427A (fr) 1961-04-12 1962-12-21 Science Union Et Compagnie Soc Nouveaux dérivés de la pipérazine et leurs préparations
GB979994A (en) 1961-07-28 1965-01-06 May & Baker Ltd Isoindolinone derivatives
US3160641A (en) 1961-08-07 1964-12-08 Atlas Chem Ind Purification of isosorbide
NL281975A (is) 1961-08-12
DE1518133B1 (de) 1961-10-05 1970-08-20 Farmaceutici Italia Verfahren zur Herstellung eines neuen hypotensiv wirkenden Hendekapeptids
DE1236523C2 (de) 1962-02-15 1975-06-12 Sanol-Arzneimittel Dr. Schwarz Gmbh, 4019 Monheim Verfahren zur herstellung von basischen phenylaethern und deren salzen
US3262977A (en) 1962-03-10 1966-07-26 Chinoin Gyogyszer Es Vegyeszet N-aralkyl-1, 1-diphenyl-propylamine derivatives
BE629910A (is) 1962-03-22
US3188329A (en) 1962-04-10 1965-06-08 Colgate Palmolive Co Diuretic anils
US3228943A (en) 1962-06-11 1966-01-11 Lumilysergol derivatives
BE639386A (is) 1962-10-30
NL300886A (is) 1962-11-23
NL301580A (is) 1962-12-11
NL142872C (is) 1963-03-28
FR2790M (fr) 1963-05-24 1964-10-16 Soc Ind Fab Antibiotiques Sifa Nouveaux dérivés des thiachromanes.
GB1069343A (en) 1963-09-10 1967-05-17 Ici Ltd Propanolamine derivatives
US3238215A (en) 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
NL127996C (is) 1963-11-19
BR6464291D0 (pt) 1963-11-26 1973-07-26 Merrell Inc Richardson Processo para preparar o novo composto quimico 1-1-di cloro-hexil-2-(2-piperidil)-etina
DE1278443C2 (de) 1963-11-30 1975-07-24 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4-disulfonamid-1-chlorbenzolen
NL128190C (is) 1964-02-07
FR1390056A (fr) 1964-04-21 1965-02-19 Holding Ceresia S A Procédé de préparation de nouveaux dérivés du tétrahydronaphtalène et produits conformes à ceux obtenus par le présent procédé ou procédé similaire
NL127065C (is) 1964-04-22
NL137318C (is) 1964-06-09
US3422107A (en) 1964-09-05 1969-01-14 Albert Ag Chem Werke Certain oxoalkyldimethylxanthines and a process for the preparation thereof
NL130749C (is) 1964-09-10
GB1078852A (en) 1964-09-30 1967-08-09 Ici Ltd Alkanolamine derivatives
NL6514807A (is) 1964-11-18 1966-05-20
NL128191C (is) 1965-01-12
US3466325A (en) 1965-04-30 1969-09-09 Haessle Ab 1-(ortho-alkenyl phenoxy) - 2-hydroxy-3-isopropylaminopropanes and the salts thereof
US3929836A (en) 1965-05-11 1975-12-30 Hoffmann La Roche 2-(2-Lower alkylamino-1-hydroxy-ethyl)-substituted benzofurans
FR1460571A (fr) 1965-06-10 1966-03-04 Innothera Lab Sa Composés thiényl acétiques et leur préparation
DE1270544B (de) 1965-06-19 1968-06-20 Beiersdorf Ag 4-Chlor-5-sulfamylsalicylsaeure-(2', 6'-dimethyl)-anilid und dessen Alkali- oder Ammonium-Salze sowie Verfahren zu deren Herstellung
DE1545575C2 (de) 1965-12-16 1970-09-10 Asta-Werke Ag, Chemische Fabrik, 4812 Brackwede N, N'-Bis- eckige Klammer auf 3"(3', 4', 5'-trimethoxybenzoyloxy)-propyl eckige Klammer zu -homopiperazin
US3360518A (en) 1966-01-03 1967-12-26 Wallace & Tiernan Inc Tetrahydro-halo-sulfamyl quinazolinones
CH472404A (de) 1966-03-04 1969-05-15 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
CH469002A (de) 1966-06-21 1969-02-28 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
FR5733M (is) 1966-09-27 1968-01-22
FR6087M (is) 1967-01-10 1968-06-04
US3541130A (en) 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
GB1160925A (en) 1967-02-08 1969-08-06 Menarini Sas 2-Substituted Benzofuran Derivatives
DE1668055B2 (de) 1967-03-10 1973-09-06 Farbwerke Hoechst AG, vormals Mei ster Lucius & Bruning, 6000 Frankfurt Basisch substituierte cyclopentylphenolaether, deren salze mit physiologisch vertraeglichen saeuren und verfahren zu deren herstellung
DE1670827C3 (de) 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
US3562257A (en) 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3857952A (en) 1967-12-22 1974-12-31 May & Baker Ltd Certain benzene derivatives useful in treating cardiac disorders
FR2003097A1 (en) 1968-03-02 1969-11-07 Takeda Chemical Industries Ltd Cpds. of general formula (I) A=CH or N Spasmolytics and peripheral vasodilators. Dose: 100-200 mg/d. (p.o). Z and X are OH or reactive
GB1203691A (en) 1968-03-06 1970-09-03 Science Union & Cie New disubstituted n-amino indoline derivatives and process for preparing them
GB1218591A (en) 1968-04-03 1971-01-06 Delalande Sa Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation
US4045482A (en) 1968-11-12 1977-08-30 Yamanouchi Pharmaceutical Co. Ltd. 4-(3-Isopropylamino-2-hydroxypropoxy indene
DE1815922C3 (de) 1968-12-20 1979-04-26 Boehringer Mannheim Gmbh, 6800 Mannheim 5-Phenyltetrazol-Derivate
GB1249490A (en) 1968-12-24 1971-10-13 Leo Pharm Prod Ltd New sulphamyl-benzoic acid derivatives
FR8120M (is) 1968-12-26 1970-08-03
US3836671A (en) 1969-02-21 1974-09-17 Ici Ltd Alkanolamine derivatives for producing beta-adrenergic blockade
GB1285038A (en) 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives
US3655663A (en) 1969-04-21 1972-04-11 Burton K Wasson 4-(3-secondary amino-2-hydroxy-proxy) 1 2 5-thiadiazoles
US3663570A (en) 1969-04-28 1972-05-16 Sankyo Co Coumarin derivatives
GB1262785A (en) 1969-04-29 1972-02-09 Orsymonde Improvements in or relating to phloroglucinol derivatives
CA956632A (en) 1969-05-16 1974-10-22 Yoshitomi Pharmaceutical Industries Phenoxy-aminopropanol derivatives
US4012444A (en) 1969-07-08 1977-03-15 Allen & Hanburys Limited 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof
BE757001A (fr) 1969-10-10 1971-03-16 Cerpha Derives heterocycliques d'acides phenoxy acetique et leur preparation
US4018824A (en) 1969-11-28 1977-04-19 Teikoku Hormone Mfg. Co., Ltd. 1-Aryloxy-3-aminopropane derivatives
US4038313A (en) 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
US3935259A (en) 1970-01-08 1976-01-27 Ciba-Geigy Corporation New amines and processes for their manufacture
SE354851B (is) 1970-02-18 1973-03-26 Haessle Ab
US3770724A (en) 1970-03-31 1973-11-06 Roussel Uclaf Process for preparing pentacyclic alkaloids
GB1308191A (en) 1970-04-06 1973-02-21 Science Union & Cie Thiochroman derivatives and a process for preparing them
US3663597A (en) 1970-05-05 1972-05-16 American Home Prod Process for the purification of cyclandelate
FR2092133B1 (is) 1970-05-06 1974-03-22 Orsymonde
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
US4059622A (en) 1970-05-27 1977-11-22 Imperial Chemical Industries Limited Alkanolamine derivatives
DE2130393C3 (de) 1970-06-22 1981-02-26 E.R. Squibb & Sons Inc., New York, N.Y. (V.St.A.) 6,7-Dihydroxy -5,6,7,8-tetrahydronaphthyloxyaminopropanole und ihre Salze mit Säuren sowie ihre Verwendung bei der Bekämpfung von Herzerkrankungen
FR2092895B1 (is) 1970-06-29 1973-07-13 Lafon Victor
AT308089B (de) 1970-10-14 1973-06-25 Degussa Verfahren zur Herstellung von neuen Thienylalkanderivaten und ihren Salzen
DE2117571C3 (de) 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
CA989411A (en) 1971-05-13 1976-05-18 Kakenyaku Kako Co. Benzofuran derivatives and preparation thereof
DE2815926A1 (de) 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US3773939A (en) 1971-11-24 1973-11-20 Janssen Pharmaceutica Nv N-arallyl-n'-aralkyl piperazine pharmaceutical compositions
BE790165A (fr) 1971-12-14 1973-02-15 Parke Davis & Co Nouveaux aminoalcanols et procede pour les preparer
BE795735A (fr) 1972-03-06 1973-06-18 Cerm Cent Europ Rech Mauvernay Nouvelles ethylenediamines substituees a activite cardiovasculaire
JPS5229318B2 (is) 1972-03-30 1977-08-01
US3910924A (en) 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
ZA732937B (en) 1972-05-05 1974-03-27 Maggioni & C Spa Non mercurial diuretics
GB1435139A (en) 1972-08-17 1976-05-12 Sumitomo Chemical Co Thiazole derivatives
US4167581A (en) 1972-12-15 1979-09-11 Imperial Chemical Industries Limited Alkanolamine derivatives and pharmaceutical compositions and uses thereof
US3985758A (en) 1973-02-20 1976-10-12 Yamanouchi Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives
GB1390748A (en) 1973-04-09 1975-04-16 Continental Pharma Alkyl and cycloalkylthiophenylalkylaminoalkanols their salts and the preparation thereof
DE2319278C2 (de) 1973-04-17 1986-02-20 Bayer Ag, 5090 Leverkusen Pharmazeutisches Mittel
US4146643A (en) 1973-12-18 1979-03-27 Sandoz Ltd. Increasing vigilance or treating cerebral insufficiency with substituted vincamines
AT334385B (de) 1973-12-20 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen
NL175059C (nl) 1974-02-23 Boehringer Mannheim Gmbh Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.
GB1501632A (en) 1974-06-28 1978-02-22 Cm Ind Aromatic ketones having cardiovascular activity
GB1477664A (en) 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
DE2419970C3 (de) 1974-04-25 1980-06-12 Hoechst Ag, 6000 Frankfurt 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung
DE2521113A1 (de) 1974-05-15 1976-03-18 Maggioni & C Spa Cycloaliphatische derivate von 3.3-diphenylpropylamin
US4338322A (en) 1975-07-02 1982-07-06 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same
US4129565A (en) 1975-07-11 1978-12-12 Nisshin Flour Milling Co., Ltd. Isocarbostyril derivatives
US4340541A (en) 1975-08-15 1982-07-20 Sandoz Ltd. 4-(2-Benzoyloxy-3-tert.-butylaminopropoxy-2-methyl indole
US4035750A (en) 1975-10-14 1977-07-12 Eastman Kodak Company Electrophotographic apparatus having improved photoconductor regenerative structure and procedure
US4105776A (en) 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4154839A (en) 1975-11-05 1979-05-15 Bayer Aktiengesellschaft 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
FR2330383A1 (fr) 1975-11-06 1977-06-03 Synthelabo Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment
US4046889A (en) 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
GB1544872A (en) 1976-06-25 1979-04-25 Sterling Drug Inc 4-hydroxyphenylalkanolamine derivatives and preparation thereof
DE2645710C2 (de) 1976-10-09 1985-06-27 Merck Patent Gmbh, 6100 Darmstadt Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung
US4466972A (en) 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
CA1147342A (en) 1977-10-12 1983-05-31 Kazuo Imai Process of producing novel phenylethanolamine derivatives
US4188390A (en) 1977-11-05 1980-02-12 Pfizer Inc. Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
IT1088554B (it) 1977-11-17 1985-06-10 F I D I A Spa Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina
JPS55301A (en) 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
IT1094076B (it) 1978-04-18 1985-07-26 Acraf Cicloalchiltriazoli
SE429652B (sv) 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
JPS559058A (en) 1978-07-06 1980-01-22 Dainippon Pharmaceut Co Ltd 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative
DE2845770A1 (de) 1978-10-19 1980-04-30 Schering Ag Neue prostacyclin-derivate und verfahren zu ihrer herstellung
IL58849A (en) 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4508729A (en) 1979-12-07 1985-04-02 Adir Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
JPS56110665A (en) 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
US4394382A (en) 1980-06-17 1983-07-19 Kowa Company, Ltd. Dihydrobenzopyran compounds and pharmaceutical composition comprising said compounds
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
ZA817261B (en) 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
US4470972A (en) 1981-04-28 1984-09-11 Schering Corporation 7-Carboxyalkylaminoacyl-1,4-dithia-7-azaspiro[4.4]-nonane-8-carboxylic acids
JPS57209270A (en) 1981-06-19 1982-12-22 Chugai Pharmaceut Co Ltd Proline derivative
GB2111978B (en) 1981-10-19 1985-05-01 Maruko Pharmaceutical Co 1 4-dihydropyridine compounds
US4410520A (en) 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
GR78413B (is) 1981-12-29 1984-09-27 Hoechst Ag
US4555502A (en) 1982-09-30 1985-11-26 Merck & Co., Inc. Aminoacyl-containing dipeptide derivatives useful as antihypertensives
DK161312C (da) 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
EP0094159B1 (en) 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dihydropyridine derivatives, their production and use
JPS6058233B2 (ja) 1982-05-24 1985-12-19 田辺製薬株式会社 2−オキソイミダゾリジン誘導体及びその製法
US4452790A (en) 1982-06-23 1984-06-05 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
US4463176A (en) 1982-09-13 1984-07-31 Mead Johnson & Company Process for resolution of optical isomers
EP0106275B1 (en) 1982-10-15 1991-03-13 Kyowa Hakko Kogyo Co., Ltd. 1,4-dihydropyridine derivatives
US4567175A (en) 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
US4678783B1 (en) 1983-11-04 1995-04-04 Asahi Chemical Ind Substituted isoquinolinesulfonyl compounds
US4654362A (en) 1983-12-05 1987-03-31 Janssen Pharmaceutica, N.V. Derivatives of 2,2'-iminobisethanol
GB8403866D0 (en) 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
JPS60222472A (ja) 1984-03-30 1985-11-07 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
US4699905A (en) 1984-04-10 1987-10-13 Sankyo Company, Limited Perhydrothiazepine derivatives, their preparation and their therapeutic use
US4672068A (en) 1984-05-04 1987-06-09 Fujirebio Kabushiki Kaisha Antihypertensive 1,4-dihydropyridines having a conjugated ester
NZ212895A (en) 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
DE3683483D1 (de) 1985-07-29 1992-02-27 Santen Pharmaceutical Co Ltd Neue benzothiazinabkoemmlinge.
US4885284A (en) 1986-01-22 1989-12-05 Nissan Chemical Industries Ltd. Dihydropyridine-5-phosphonic acid cyclic propylene ester
US5138069A (en) 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
CA1319144C (en) 1986-11-14 1993-06-15 Quirico Branca Tetrahydronaphthalene derivatives
ATE61588T1 (de) 1987-08-03 1991-03-15 Delagrange Lab 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
US5185351A (en) 1989-06-14 1993-02-09 Smithkline Beecham Corporation Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
DE122007000050I1 (de) 1990-02-19 2007-11-08 Novartis Ag Acylverbindungen
US5270317A (en) 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
US5196444A (en) 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
US5440056A (en) 1992-04-17 1995-08-08 Abbott Laboratories 9-deoxotaxane compounds
US6177401B1 (en) 1992-11-13 2001-01-23 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
KR20010110310A (ko) * 1998-12-23 2001-12-12 로저 에이. 윌리암스 종양 치료에 사이클로옥시게나제-2 억제제와 하나 이상의항종양제를 조합치료법으로서 사용하는 방법
EP1303283B1 (en) * 2000-07-27 2004-11-17 Nucryst Pharmaceuticals Corp. Use of noble metals for the manufacture of a medicament to treat hyperproliferative skin disorders and diseases
SK5862003A3 (en) * 2000-11-28 2004-05-04 Pfizer Prod Inc Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents

Also Published As

Publication number Publication date
MXPA05001958A (es) 2005-04-28
JP3835763B2 (ja) 2006-10-18
ATE502635T1 (de) 2011-04-15
EA200500234A1 (ru) 2005-08-25
TW200403057A (en) 2004-03-01
PL375713A1 (en) 2005-12-12
HK1079106A1 (en) 2006-03-31
US20070197517A1 (en) 2007-08-23
CA2495962A1 (en) 2004-03-04
CN1681495B (zh) 2010-05-12
EP1545519B1 (en) 2011-03-23
JP2006500374A (ja) 2006-01-05
ES2362998T3 (es) 2011-07-18
PE20040993A1 (es) 2004-12-29
HRP20050163A2 (en) 2005-06-30
WO2004017964A1 (en) 2004-03-04
AP2005003232A0 (en) 2005-03-31
GT200300177A (es) 2004-04-19
KR20050058351A (ko) 2005-06-16
MA27385A1 (fr) 2005-06-01
GEP20074134B (en) 2007-06-25
RS20050106A (en) 2007-11-15
KR100668539B1 (ko) 2007-01-16
NO20050621L (no) 2005-05-18
ECSP055618A (es) 2005-04-18
PA8580201A1 (es) 2004-08-31
TNSN05051A1 (fr) 2007-05-14
AU2003250483A1 (en) 2004-03-11
CN1681495A (zh) 2005-10-12
EP1545519A1 (en) 2005-06-29
OA12905A (en) 2006-10-13
AR040995A1 (es) 2005-04-27
DE60336485D1 (de) 2011-05-05
IL166545A0 (en) 2006-01-15
BR0313593A (pt) 2005-07-12
CR7693A (es) 2005-06-15

Similar Documents

Publication Publication Date Title
IS7670A (is) Samsett meðferð fyrir offjölgunar sjúkdóma
NO20052914D0 (no) Terapeutiske forbindelser
ATE465180T1 (de) Therapeutische anti-igfr1-antikörper- kombinationen
DE60308332D1 (de) Chinazolinverbindungen mit therapeutischem nutzen
DE50311558D1 (de) Inhalationstherapievorrichtung
NO20050689L (no) Terapeutisk anvendelse
NO20033205D0 (no) Terapeutiske kromanforbindelser
IS7825A (is) Meðferðarfræðileg meðhöndlun
DK1597171T3 (da) Terapeutisk mikroskum
NL1024677A1 (nl) Therapeutische prolinederivaten.
NO20044188L (no) Kontrollerte frigjoringsdoseformer
NO20053189D0 (no) HVC-kombinasjonsterapi.
DK1618130T3 (da) Terapeutisk cancervaccine
DE60328516D1 (de) Thia-epothilon derivate zur krebsbehandlung
ATA15642003A (de) Orthopädische liege
DE10240912B4 (de) Strahlentherapiegerät
NO20030716D0 (no) Stimulator for vagina
NO20042850L (no) Kreftbehandling
SE0200450D0 (sv) Therapeutic agents
SE0203826D0 (sv) Therapeutic agents
SE0203451D0 (sv) Therapeutic Heterocycles
SE0203450D0 (sv) Therapeutic heterocycles
SE0403119D0 (sv) Therapeutic agents
SE0400718D0 (sv) Therapeutic agents
SE0302428D0 (sv) Therapeutic heterocycles