DE60328516D1 - Thia-epothilon derivate zur krebsbehandlung - Google Patents

Thia-epothilon derivate zur krebsbehandlung

Info

Publication number
DE60328516D1
DE60328516D1 DE60328516T DE60328516T DE60328516D1 DE 60328516 D1 DE60328516 D1 DE 60328516D1 DE 60328516 T DE60328516 T DE 60328516T DE 60328516 T DE60328516 T DE 60328516T DE 60328516 D1 DE60328516 D1 DE 60328516D1
Authority
DE
Germany
Prior art keywords
thia
cancer treatment
epothilone derivatives
epothilone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60328516T
Other languages
English (en)
Inventor
Wolfgang Richter
Lutz Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2002155681 external-priority patent/DE10255681A1/de
Priority claimed from DE10327472A external-priority patent/DE10327472A1/de
Application filed by Individual filed Critical Individual
Priority to DE60328516T priority Critical patent/DE60328516D1/de
Application granted granted Critical
Publication of DE60328516D1 publication Critical patent/DE60328516D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60328516T 2002-11-28 2003-11-28 Thia-epothilon derivate zur krebsbehandlung Expired - Lifetime DE60328516D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE60328516T DE60328516D1 (de) 2002-11-28 2003-11-28 Thia-epothilon derivate zur krebsbehandlung

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2002155681 DE10255681A1 (de) 2002-11-28 2002-11-28 Neue Makrocyclen zur Behandlung von Krebserkrankungen
DE10327472A DE10327472A1 (de) 2003-06-18 2003-06-18 Neue Makrocyclen zur Behandlung von Krebserkrankungen
PCT/EP2003/013412 WO2004048372A1 (en) 2002-11-28 2003-11-28 Thia-epothilone derivatives for the treatment of cancer
DE60328516T DE60328516D1 (de) 2002-11-28 2003-11-28 Thia-epothilon derivate zur krebsbehandlung

Publications (1)

Publication Number Publication Date
DE60328516D1 true DE60328516D1 (de) 2009-09-03

Family

ID=32395017

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60328516T Expired - Lifetime DE60328516D1 (de) 2002-11-28 2003-11-28 Thia-epothilon derivate zur krebsbehandlung

Country Status (7)

Country Link
US (1) US7645782B2 (de)
EP (1) EP1567524B1 (de)
AU (1) AU2003296242A1 (de)
DE (1) DE60328516D1 (de)
DK (1) DK1567524T3 (de)
ES (1) ES2330517T3 (de)
WO (1) WO2004048372A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE423780T1 (de) * 2002-07-15 2009-03-15 Biotechnolog Forschung Gmbh Makrozyclen zur behandlung von krebserkrankungen
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
WO2004018478A2 (en) 2002-08-23 2004-03-04 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
EP2394640A1 (de) 2010-05-21 2011-12-14 MediGene AG Verbesserte liposomale Formulierungen von lipophilen Verbindungen
EP2708243A1 (de) 2012-09-17 2014-03-19 OntoChem GmbH Rezeptor-Ligand-verbundene zytotoxische Moleküle

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605599B1 (en) * 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
US6699997B2 (en) * 2000-06-28 2004-03-02 Teva Pharmaceutical Industries Ltd. Carvedilol
ATE423780T1 (de) * 2002-07-15 2009-03-15 Biotechnolog Forschung Gmbh Makrozyclen zur behandlung von krebserkrankungen
DE10232094A1 (de) * 2002-07-15 2004-02-05 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) 5-Thiaepothilone und 15-disubstituierte Epothilone

Also Published As

Publication number Publication date
AU2003296242A1 (en) 2004-06-18
US20060128966A1 (en) 2006-06-15
WO2004048372A1 (en) 2004-06-10
DK1567524T3 (da) 2009-11-16
ES2330517T3 (es) 2009-12-11
EP1567524B1 (de) 2009-07-22
US7645782B2 (en) 2010-01-12
EP1567524A1 (de) 2005-08-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition